15 completed, 8 recruiting, 8 unknown, 3 active not recruiting. 22 Not applicable, 3 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 22 | Completed 7, Unknown 6, Enrolling by invitation 3, Recruiting 3, Active not recruiting 2, Not yet recruiting 1 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
| Phase 3 | 1 | Completed 1 |
Follow Dentofacial Deformities: new trials by email Literature Review of Dentofacial Deformities trials Research Report on Dentofacial Deformities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Orthognathic Surgery and Obstructive Sleep Apnea Assessed by Mandibular Jaw Movement Monitoring (SUNRISE-ORTHO) Orthognathic surgery (BSSO with or without Le Fort I osteotomy), Sunrise mandibular jaw movement monitoring, Facial multidetector CT in natural head position - Obstructive Sleep Apnea, Sleep Apnea, Obstructive | Not yet recruiting | CHR Sambre et Meuse Site Meuse | 25 | 2026-11-04 | 2026-11-03 | |
| Comparing 3D-Printed and Milled Titanium Plates in Jaw Surgery (Le Fort I): Accuracy and Operative Time 3D-Printed Patient-Specific Titanium Plates, Milled Patient-Specific Titanium Plates - Malocclusion, Angle Class II, Malocclusion, Angle Class III | Not applicable | Recruiting | Future University in Egypt | 12 | 2026-10-01 | 2026-09-25 |
| Clinical and Radiographic Evaluation of Low Sagittal Medial Ramus Osteotomy for Treatment of Skeletal Class II and Class III Malocclusion Low Sagittal Medial Ramus Osteotomy - Skeletal Class II Malocclusion, Skeletal Class III Malocclusion | Not applicable | Not yet recruiting | Al-Azhar University | 11 | 2026-09-01 | 2026-08-05 |
| Changes in Depression and Esthetic Perception After Orthognathic Surgery Dentofacial Deformities, Malocclusions | Recruiting | Kırıkkale University | 18 | 2026-06-20 | 2026-07-16 | |
| Research on Deep Learning-Based Intelligent Diagnosis and Treatment Malocclusion, Craniofacial Morphology | Not yet recruiting | Xi'an Jiaotong University | 2000 | 2026-05-01 | 2026-04-27 | |
| Evaluation of Emotional Responses Using the I-Motions System and Self-assessment Questionnaires, and Assessment of Postoperative Anatomical and Structural Units (TMJ and Masticatory Muscles) in Orthognathic Surgery Patients Observational Assessment - Orthognathic Surgery, Malocclusions | Not applicable | Enrolling by invitation | Lithuanian University of Health Sciences | 100 | 2026-03-03 | 2026-03-17 |
| Effects of Local Ketamine in Orthognathic Procedures Ketamine, Articaine Hydrochloride + Epinephrine - Dentofacial Deformities, Analgesia | Not applicable | Active not recruiting | Bezmialem Vakif University | 40 | 2025-06-21 | 2026-03-27 |
| Lymphatic Drainage Massage and Melatonin in Post-Orthognathic Surgery Pain and Edema no intervention, lymphatic drainage massage, oral melatonin tablet - Dentofacial Deformities, Edema | Not applicable | Enrolling by invitation | Bezmialem Vakif University | 40 | 2025-03-30 | 2025-07-14 |
| Effect of Proximal Segment Positioning on Postoperative Condylar Remodeling in Bimaxillary Orthognathic Surgery manuel positioning group, mandibular basis osteotomy - Dentofacial Deformities, Dentofacial Anomalies [Including Malocclusion] and Other Disorders of Jaw (M26-M27) | Not applicable | Enrolling by invitation | Bezmialem Vakif University | 40 | 2025-03-30 | 2025-06-24 |
| Preoperative Anxiety and Its Impact on Intraoperative Hemodynamics and Postoperative Pain, Edema, and Trismus in Orthognathic Surgery Dentofacial Deformities | Recruiting | Istanbul Medipol University Hospital | 45 | 2025-02-01 | 2026-02-27 | |
| Quantitative Evaluation of Attention to Faces After Orthognathic Surgery With Eye-tracking photographs - Dentofacial Deformities, Orthognathic Surgery | Not applicable | Recruiting | Centre Hospitalier Universitaire, Amiens | 60 | 2024-07-02 | 2026-09-08 |
| Frenuloplasty for Speech and Myofunctional Outcomes Lingual frenuloplasty - Ankyloglossia, Speech Delay | Not applicable | Unknown | The Oregon Clinic | 50 | 2024-07-01 | 2024-04-03 |
| Splintless Virtual Surgical Plan with Mandible-first Technique: 3D Accuracy Analysis Bimaxillary Osteotomy - Dentofacial Deformities | Unknown | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | 28 | 2024-04-24 | 2025-04-02 | |
| Patient-Specific vs. Conventional Positioning in Sagittal Split Ramus Osteotomy Custom-made positioning appliance-assisted mandibular segment repositioning, Conventional Manual Positioning - Dentofacial Deformities | Not applicable | Recruiting | Sümer Münevveroğlu | 30 | 2024-01-25 | 2025-08-15 |
| Augmented Reality for Orthognatic Surgery Patient Education Patient consultation - Malocclusion, Dentofacial Deformities | Phase 2 / Phase 3 | Completed | University Medical Center Groningen | 60 | 2023-10-01 | 2025-03-30 |
| Custom Titanium Plates vs. 3D Splints in LeFort I Osteotomy Patient-Specific Titanium Plates, 3D-Printed Intermediate Splint - Dentofacial Deformities | Not applicable | Completed | Al-Azhar University | 12 | 2023-01-10 | 2025-04-25 |
| 3D Photogrammetry Versus Commercial Scanners for Accurate Repositioning of the Maxilla for Correction of the Dentofacial Deformity. Maxillary Segment Repositioning - Dentofacial Deformities | Not applicable | Unknown | Cairo University | 24 | 2023-01-09 | 2023-03-06 |
| Comparison Between Two Techniques to Reposition the Maxilla After le Fort 1 Orthognathic surgery (lefort1) - Dentofacial Deformities, Le Fort; I | Not applicable | Completed | Alexandria University | 14 | 2022-11-15 | 2023-11-15 |
| Stability of Two Designs of Patient Specific Osteosynthesis For Fixation of LeFort 1 Osteotomy in Orthognathic Surgery Stability of a two piece PSI deign in splintless maxillary orthognathic surgery, Stability of a one piece PSI deign in splintless maxillary orthognathic surgery - Dentofacial Deformities | Not applicable | Unknown | Cairo University | 34 | 2022-09-05 | 2022-09-02 |
| Skeletal Stability of Le Fort I Osteotomy Using Patient-specific Osteosynthesis Compared to Mini-plate Fixation for Patients With Dentofacial Disharmony Bimaxillary orthognathic surgery using conventional plates, Bimaxillary orthognathic surgery using patient specific plates - Dentofacial Deformities | Not applicable | Unknown | Hassan Fahmy Hassan Alnimr | 30 | 2022-05-26 | 2022-06-01 |
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Malocclusion (6) · Retrognathia (3) · Edema (2) · Jaw Abnormalities (2) · Malocclusion, Angle Class III (2) · Mandibular Neoplasms (2) · Maxillary Neoplasms (2) · Maxillofacial Abnormalities (2) · Pain (2) · Prognathism (2) · Agnosia (1) · Ankyloglossia (1) · Anxiety Disorders (1) · Congenital Abnormalities (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (40) · Musculoskeletal Abnormalities (40) · Musculoskeletal Diseases (40) · Stomatognathic Diseases (40) · Stomatognathic System Abnormalities (40) · Congenital Abnormalities (39) · Craniofacial Abnormalities (39) · Maxillofacial Abnormalities (38) · Tooth Diseases (9) · Nervous System Diseases (7) · Pathological Conditions, Signs and Symptoms (7) · Jaw Diseases (6) · Neurologic Manifestations (6) · Signs and Symptoms (6) · Mandibular Diseases (5)
Orthognathic Surgery (6) · Melatonin (2) · Anesthetics, Local (1) · Carticaine (1) · Cefazolin (1) · Cephalexin (1) · Clindamycin (1) · Epinephrine (1) · Ketamine (1) · Manual Lymphatic Drainage (1) · Moire Topography (1) · Orthodontics (1) · Ropivacaine (1) · beta-sitosterol oleate (1)
Bezmialem Vakif University (3) · Cairo University (3) · The University of Hong Kong (3) · Al-Azhar University (2) · Alexandria University (2) · Istanbul Medipol University Hospital (2) · Servei Central d'Anestesiologia (2) · Assistance Publique - Hôpitaux de Paris (1) · Atlantic Center for Oral and Maxillofacial Surgery (1) · CHR Sambre et Meuse Site Meuse (1) · Centre Hospitalier Universitaire, Amiens (1) · Future University in Egypt (1) · Hassan Fahmy Hassan Alnimr (1) · Hospital Carlos Van Buren (1) · I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio (1)
Egypt (8) · Turkey (Türkiye) (7) · France (3) · Hong Kong (3) · Brazil (2) · Canada (2) · Italy (2) · Spain (2) · United States (2) · Belgium (1) · Chile (1) · Germany (1) · Lithuania (1) · Netherlands (1) · Sweden (1)
Alexandre M Borba, DDS, MSc (1) · Claudio Marchetti, MD (1) · Crystal TY Lee, BDS (HKU) (1) · Dina Y Girgis, Master (1) · Giovanni Gasperini, master (1) · Gloria Molins (1) · Hassan Alnimr (1) · Hesham O Morsi, MDSc (1) · J Kraeima, dr. (1) · Konstantinia Almpani, D.D.S. (1) · Laura A Jacox, PhD, DMD, MS (1) · Martin Bengtsson, DDS, PhD (1)
PMID 24011464, PMID 24679851, PMID 26606321, PMID 29496055, PMID 31230767, PMID 31892445, PMID 32572853, PMID 37858599, PMID 38253318, PMID 41460808, PMID 42069961