350 completed, 149 unknown, 53 recruiting, 40 withdrawn. 351 Not applicable, 126 Phase 2, 71 Phase 1, 48 Phase 4, 36 Phase 3.
Follow Cicatrix: new trials by email Literature Review of Cicatrix trials Research Report on Cicatrix
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Post-Operative Use of FS2 to Mitigate Scarring in Burn Patients IP1 control cream (Vehicle base), IP2 - 0.5% w/w FS2 - Burn Scar, Burn Wound | Phase 2 / Phase 3 | Recruiting | Birch BioMed Inc | 70 | 2027-03-01 | 2026-09-30 |
| Phase II Clinical Study on Preliminary Efficacy and Safety of ETD-001 Gel for Hypertrophic Scars ETD-001 gel, Placebo - Hypertrophic Scars | Phase 2 | Not yet recruiting | Etern Therapeutics Wuxi Limited | 90 | 2027-02-28 | 2026-10-23 |
| Dermabrasion for Free Flap Aesthetic Enhancement Dermabrasion - Scar Conditions and Fibrosis of Skin | Not applicable | Not yet recruiting | Milton S. Hershey Medical Center | 40 | 2027-01-01 | 2026-08-24 |
| The Effects of Timolol On Healing and Cosmesis of Mohs Scalp Wounds: An Open Label Trial Topical Timolol, Normal Saline - Surgical Wounds, Mohs Surgery | Phase 2 | Not yet recruiting | Geisinger Clinic | 45 | 2026-12-01 | 2026-10-14 |
| Effect of an Intraoperative Polynucleotide Injection on Scar Quality After Thyroidectomy Polynucleotide (PN-HPT), Sterile 0.9% Sodium Chloride - Postoperative Surgical Scar, Scar | Not applicable | Not yet recruiting | Dr. Lutfi Kirdar Kartal Training and Research Hospital | 80 | 2026-11-20 | 2026-09-23 |
| Surgical Dressing Study Comparing SYLKE vs Other Common Incisional Dressings Following Abdominoplasty/Panniculectomy Patients SYLKE, Dermabond Prineo, Paper Tape - Hypertrophic Surgical Scar, Medical Adhesive Related Skin Injury | Not applicable | Not yet recruiting | University of Missouri-Columbia | 100 | 2026-11-01 | 2026-10-16 |
| Pre-marketing Trial to Assess Safety and Efficacy of 'Volumizing Filler Based on Hyaluronic Acid and Recombinant Collagen' Karisma - Wrinkle, Scar | Not applicable | Recruiting | Taumedika s.r.l. | 40 | 2026-11-01 | 2026-10-02 |
| Autologous Skin Cell Suspension (RECELL®) for Accelerated Healing of Split-Thickness Skin Graft Donor Sites: A Randomized, Intra-Patient (Split-Site) Controlled Trial RECELL® Autologous Cell Harvesting Device, Standard Transparent Film Dressing - Skin Graft Donor Site, Wound Healing | Not applicable | Not yet recruiting | University of California, Davis | 50 | 2026-11-01 | 2026-10-22 |
| Reducing Wound Complications in Breast Surgery Using hACM Dehydrated Human Amnion Chorion Membrane - Surgical Wound Healing, Scar Tissue | Phase 4 | Not yet recruiting | Rutgers, The State University of New Jersey | 200 | 2026-11-01 | 2026-10-20 |
| Lipofilling in Operative Hand Fracture Treatment Lipofilling in Operative Treatment of Proximal Phalanx Fractures and Related Tenolysis - Adhesions, Hand Fractures | Not applicable | Not yet recruiting | Jeroen Bosch Ziekenhuis | 130 | 2026-10-19 | 2026-09-11 |
| Recurrence of Extremity Joint Contracture After Z-Plasty Versus Full-Thickness Skin Graft Z-Plasty, Full-Thickness Skin Graft - Joint Contracture, Contracture | Not yet recruiting | Universitas Sebelas Maret | 300 | 2026-10-13 | 2026-10-21 | |
| Disposable Noninvasive Skin Closure for Promoting Postoperative Wound Healing and Preventing Surgical Skin Scarring Disposable Noninvasive Skin Closure Device (Shanghai Zhizhong Medical Technology Co., Ltd. Catalog No.: 240430PFF) - Scar | Not applicable | Recruiting | Peking University Third Hospital | 25 | 2026-10-08 | 2026-10-09 |
| SCARFREE-001: Verteporfin for Scar Prevention Verteporfin Injection, Saline injection - Surgical Scar | Phase 2 | Not yet recruiting | Odense University Hospital | 12 | 2026-10-01 | 2026-10-05 |
| Hypertrophic Scar Prosthetic Pressure in Burn Amputee Skin assessment of prothesis interface and control area, Interface pressure - Amputation Stump, Burn Injury | Not yet recruiting | Centre hospitalier de l'Université de Montréal (CHUM) | 12 | 2026-09-01 | 2026-09-30 | |
| Carbon Dioxide Laser-Assisted Delivery of Triamcinolone With or Without 5-Fluorouracil for Hypertrophic Burn Scars Fractional Ablative CO₂ Laser, Triamcinolone Acetonide, Fluorouracil (5-FU) - Burn, Hypertrophic Scars | Not applicable | Not yet recruiting | University of California, Davis | 65 | 2026-08-22 | 2026-08-24 |
| The Study Examines the Efficacy of Treating Limb Scars Using a Combined Pressure Garment and Silicone Sheet Compared to Treatment With a Pressure Garment Alone. The Study Aims to Develop a Comprehensive Scar Assessment Framework, Integrating Objective and Subjective Tools to Evaluate Treatment Pressure Garment and Silicone Sheet Therapy, Pressure Garment Therapy - Scars, Scars Formation | Not applicable | Not yet recruiting | Sheba Medical Center | 60 | 2026-08-15 | 2026-08-04 |
| Polidocanol 1% and Steroid in Keloids and Hypertrophic Scars Group 1 (polidocanol 1% group):, Group 2 (Triamcinolone acetonide group):, Group 3 (combined Triamcinolone acetonide and polidocanol 1% group): - Keloid and Hypertrophic Scars | Not applicable | Not yet recruiting | Sohag University | 90 | 2026-08-01 | 2026-05-26 |
| A Clinical Study on the Safety and Efficacy of Wide-Band Ultrasound Combined With Traditional Chinese Medicine Preparations in the Prevention and Treatment of Keloids Wide-Band Ultrasound, traditional Chinese medicine - Keloid | Phase 1 / Phase 2 | Not yet recruiting | Fujian Medical University Union Hospital | 120 | 2026-08-01 | 2026-07-01 |
| Intralesional Cryosurgery Alone Versus Combined With 5-FU and Triamcinolone for Keloids Intralesional Cryotherapy + Saline Injection, Intralesional Cryotherapy + TAC/5-FU Injection - Keloid | Not applicable | Not yet recruiting | Assiut University | 32 | 2026-07-01 | 2026-04-13 |
| Scar Gel Product Family Clinical Investigation Dermatix, Dermatix Ultra - Hypertrophic Scars, Keloids | Not yet recruiting | Hanson Medical, Inc. | 150 | 2026-07-01 | 2026-07-06 |
Showing 20 of 690. Sign in to see all of them.
Keloid (134) · Cicatrix, Hypertrophic (128) · Tissue Adhesions (121) · Burns (45) · Surgical Wound (21) · Fibrosis (19) · Acne Vulgaris (17) · Hypertrophy (14) · Pain (12) · Wounds and Injuries (11) · Gynatresia (9) · Cutis Laxa (7) · Infections (7) · Pain, Postoperative (7)
Pathological Conditions, Signs and Symptoms (690) · Pathologic Processes (688) · Fibrosis (671) · Skin and Connective Tissue Diseases (198) · Connective Tissue Diseases (146) · Collagen Diseases (134) · Wounds and Injuries (73) · Skin Diseases (65) · Neoplasms (39) · Signs and Symptoms (39) · Pathological Conditions, Anatomical (30) · Neurologic Manifestations (28) · Urogenital Diseases (25) · Neoplasms by Histologic Type (24)
TGFB3 protein, human (20) · Sodium Chloride (16) · Triamcinolone Acetonide (16) · Botulinum Toxins, Type A (15) · Saline Solution (15) · Lasers, Solid-State (8) · Percutaneous Collagen Induction (8) · Botulinum Toxins (7) · Laser Therapy (7) · Lasers (7) · Lasers, Dye (6) · Silicone Gels (6) · Dermabrasion (5) · Fluorouracil (5) · Lidocaine (5)
Renovo (25) · Cairo University (16) · University of California, Davis (14) · Massachusetts General Hospital (9) · Radboud University Medical Center (9) · Tirgan, Michael H., M.D. (8) · Chang Gung Memorial Hospital (7) · Henry Ford Health System (6) · Pfizer (6) · University Hospital, Ghent (6) · University of British Columbia (6) · University of Miami (6) · Alexandria University (5) · Assiut University (5) · Cutera Inc. (5)
United States (238) · China (43) · Egypt (39) · United Kingdom (32) · Canada (28) · Netherlands (26) · Taiwan (20) · Turkey (Türkiye) (20) · Germany (19) · South Korea (19) · Italy (18) · France (17) · Belgium (13) · Brazil (11) · Denmark (11)
Michael H Tirgan, MD (7) · Daniel Eisen, MD (6) · Jonathan Duncan (6) · David Ozog, MD (4) · Mihaela Fratila (4) · Harry van Goor, MD, PhD (3) · Herbert B Slade, MD (3) · James Bush (3) · Jeremy Bond (3) · Keyvan Nouri, MD (3) · Michael J Davies (3) · Murad Alam, MD (3) · Pamela Pavco, PhD (3) · Patricia Krantz (3)
PMID 39115183, PMID 19362676, PMID 10924629, PMID 12028528, PMID 12834941, PMID 15105384, PMID 15113289, PMID 15253184, PMID 16079683, PMID 20927486, PMID 27173082, PMID 27420903, PMID 28007752, PMID 29499740, PMID 30087573, PMID 35426735, PMID 8706941, PMID 8730623, PMID 9418714, PMID 1003586, PMID 10077078, PMID 10432121, PMID 10635174, PMID 10808705, PMID 10927682, PMID 11242330, PMID 11348456, PMID 11525858, PMID 11735062, PMID 11807470, PMID 11887386, PMID 12028527, PMID 12032371, PMID 12140476, PMID 12142678, PMID 12423299, PMID 12534517, PMID 12699951, PMID 12711943, PMID 12845617, PMID 12877429, PMID 15001284, PMID 15119583, PMID 15140214, PMID 15209788, PMID 15216537, PMID 15365369, PMID 15545541, PMID 15996419, PMID 16009415
2016 (2), 1KM1CA156708-01 (1), 2009 (1), 2014 (1), 2025 (1), I21RX004110 (1), K01HL096434 (1), R01EY018184 (1), R21HL096123 (1), U01DK111510 (1)