18 completed, 2 terminated, 1 not yet recruiting, 1 recruiting. 23 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 23 | Completed 18, Terminated 2, Not yet recruiting 1, Recruiting 1, Withdrawn 1 |
Follow Spinal Curvatures: new trials by email Literature Review of Spinal Curvatures trials Research Report on Spinal Curvatures
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tegileridine for Postoperative Pain After Adolescent Scoliosis Surgery Tegileridine, morphine - Scoliosis; Adolescence, Pain After Surgery | Phase 4 | Recruiting | Peking Union Medical College Hospital | 171 | 2026-04-08 | 2026-10-13 |
| Postoperative Steroid Use in Adolescent Idiopathic Scoliosis and Neuromuscular Scoliosis Patients Dexamethasone - Neuromuscular Scoliosis, Adolescent Idiopathic Scoliosis | Phase 4 | Not yet recruiting | Children's Hospital Los Angeles | 100 | 2025-11-01 | 2025-03-05 |
| The Effect of Dexamethasone Administration Route and Local Anesthetic Concentration on Pain, Inflammatory Response, and Neuromonitoring in Children Undergoing Scoliosis Correction perineural Dexamethasone, intravenous Dexamethasone - Scoliosis Idiopathic Adolescent | Phase 4 | Completed | Poznan University of Medical Sciences | 60 | 2025-02-01 | 2026-10-19 |
| Dexmedetomidine for ESPB in Pain Management After Pediatric Idiopathic Scoliosis Surgery Dexmedetomidine, 0.9%NaCl - Scoliosis Idiopathic, Scoliosis | Phase 4 | Completed | Poznan University of Medical Sciences | 60 | 2025-02-01 | 2026-04-13 |
| A Comparison Between Palonosetron Versus Granisetron as PONV Prophylaxis in Scoliotic Patients Undergoing Spine Surgery Palonosetron (Group P), Granisetron (Group G) - Postoperative Nausea and Vomiting, Scoliosis | Phase 4 | Completed | University of Malaya | 74 | 2025-01-06 | 2026-08-20 |
| Dexamethasone for ESPB in Pain Management After Pediatric Idiopathic Scoliosis Surgery Dexamethasone, 0.9%NaCl - Scoliosis, Scoliosis Idiopathic | Phase 4 | Completed | Poznan University of Medical Sciences | 60 | 2024-10-01 | 2025-11-24 |
| Dexamethasone Vs. Dexmedetomidine for ESPB in Pain Management After Pediatric Idiopathic Scoliosis Surgery 0.9% sodium chloride, Dexamethasone, Dexmedetomidine - Scoliosis Idiopathic, Scoliosis; Adolescence | Phase 4 | Completed | Poznan University of Medical Sciences | 90 | 2023-10-17 | 2025-01-21 |
| Palonosetron vs Ondansetron In PONV Prophylaxis Among Idiopathic Scoliosis Patients Palonosetron, Ondansetron - Idiopathic Scoliosis, Postoperative Nausea and Vomiting | Phase 4 | Completed | University of Malaya | 92 | 2023-06-01 | 2024-12-10 |
| IV Methadone Vs EXPAREL Erector Spinae Plane Blockade in Pediatric Subjects Undergoing Idiopathic Scoliosis Correction Methadone, Liposomal bupivacaine (LB, Exparel) - Adolescent Idiopathic Scoliosis, Juvenile Idiopathic Scoliosis | Phase 4 | Completed | Dr. Casey Stondell, MD | 30 | 2022-10-19 | 2024-10-04 |
| Effect of Prophylactic Fibrinogen Concentrate In Scoliosis Surgery Fibrinogen Concentrate Human - Fibrinogen, Spine Deformity | Phase 4 | Completed | Brno University Hospital | 32 | 2022-06-06 | 2026-10-16 |
| Bacterial Contamination: Iodine vs Saline Irrigation in Pediatric Spine Surgery Povidone-Iodine, Normal Saline - Surgical Site Infection | Phase 4 | Completed | Boston Children's Hospital | 173 | 2017-07-13 | 2021-05-10 |
| The Effects of Fibrinogen Concentrate Infusion on Blood Loss and Allogeneic Blood Conservation in Scoliosis Surgery Fibrinogen Concentrate Human, Normal saline - Scoliosis; Adolescence, Bleeding | Phase 4 | Completed | Peking Union Medical College Hospital | 102 | 2017-06-14 | 2020-03-02 |
| Effect of Pregabalin on Immediate Post-operative and Longterm Pain Pregabalin, Sugar pill, Oxycodone - Scoliosis, Spondylolisthesis | Phase 4 | Completed | Turku University Hospital | 64 | 2015-08-01 | 2020-10-19 |
| Posterior Spinal Fusion With Two Energy Dissection Techniques Ultrasonic Dissection (UD), Electrocautery Dissection (ED) - Scoliosis | Phase 4 | Terminated | Ethicon Endo-Surgery | 64 | 2015-06-01 | 2018-02-19 |
| Effect of Sugammadex for Muscle Motor Response and Awareness in Intraoperative Wakeup Sugammadex, Neostigmine - Spinal Curvatures | Phase 4 | Completed | Cukurova University | 60 | 2015-03-01 | 2018-03-05 |
| Comparison of Actifuse ABX and Local Bone in Spinal Surgery Multilevel Spinal fusion with Actifuse ABX® - Scoliosis, Kyphosis | Phase 4 | Terminated | Ohio State University | 14 | 2013-03-01 | 2017-04-28 |
| Effects of Dexmedetomidine on the Postoperative Experience in Children dexmedetomidine, Midazolam, fentanyl - Failed Moderate Sedation During Procedure | Phase 4 | Completed | Inonu University | 42 | 2012-02-01 | 2012-12-12 |
| Low Dose Ketamine Study on Opioid Tolerance and Hyperalgesia Ketamine, Normal Saline - Idiopathic Scoliosis, Spondylolisthesis | Phase 4 | Completed | Julia Finkel | 54 | 2010-01-01 | 2016-01-14 |
| Intrathecal Morphine Versus Epidural Extended Release Morphine for Pediatric Patients Undergoing Spinal Fusion Intrathecal morphine, Extended Release Epidural Morphine - Pain Management, Spinal Fusion | Phase 4 | Completed | University of Colorado, Denver | 84 | 2008-12-01 | 2020-04-22 |
| Tranexamic Acid (TXA) Versus Epsilon Aminocaproic Acid (EACA) Versus Placebo for Spine Surgery Tranexamic Acid, Normal Saline, Epsilon aminocaproic acid - Scoliosis | Phase 4 | Completed | NYU Langone Health | 177 | 2008-12-01 | 2018-01-17 |
Showing 20 of 23. Sign in to see all of them.
Scoliosis (22) · Agnosia (2) · Hemorrhage (2) · Pain (2) · Postoperative Nausea and Vomiting (2) · Spondylolisthesis (2) · Disseminated Intravascular Coagulation (1) · Hemostatic Disorders (1) · Hyperalgesia (1) · Kyphosis (1) · Lordosis (1) · Pain, Postoperative (1) · Surgical Wound Infection (1)
Bone Diseases (23) · Musculoskeletal Diseases (23) · Spinal Diseases (23) · Pathological Conditions, Signs and Symptoms (9) · Pathologic Processes (6) · Signs and Symptoms (6) · Neurologic Manifestations (4) · Postoperative Complications (4) · Nervous System Diseases (3) · Nausea (2) · Neurobehavioral Manifestations (2) · Perceptual Disorders (2) · Signs and Symptoms, Digestive (2) · Spondylolysis (2)
Saline Solution (5) · Dexamethasone (3) · Dexmedetomidine (3) · Sodium Chloride (3) · Fibrinogen (2) · Palonosetron (2) · Aminocaproic Acid (1) · Antiemetics (1) · Bupivacaine (1) · Fentanyl (1) · Granisetron (1) · Ketamine (1) · Methadone (1) · Midazolam (1) · Morphine (1)
Poznan University of Medical Sciences (4) · Peking Union Medical College Hospital (2) · Shriners Hospitals for Children (2) · University of Malaya (2) · Boston Children's Hospital (1) · Brno University Hospital (1) · Children's Hospital Los Angeles (1) · Cukurova University (1) · Dr. Casey Stondell, MD (1) · Ethicon Endo-Surgery (1) · Inonu University (1) · Julia Finkel (1) · NYU Langone Health (1) · Ohio State University (1) · Queen's University (1)
United States (10) · Poland (4) · China (2) · Malaysia (2) · Turkey (Türkiye) (2) · Canada (1) · Czechia (1) · Finland (1)
Anthony Scaduto, MD (1) · Baron S Lonner, MD (1) · Casey Stondell, MD (1) · Daniel Borschneck, MD (1) · Ebru Biricik (1) · Edmund Kassis, M.D. (1) · Finkel C Julie, MD (1) · Lindsay Andras, MD (1) · Ling Lan, Doctor (1) · Michael Glotzbecker, MD (1) · Mindy Cohen, MD (1) · Mohd Shahnaz Hasan, MAnaes, MBBS (1) · Nantni Kumaran, MBBS (1) · Pestieau Sophie, MD (1)
PMID 15915040, PMID 16306743, PMID 20370916, PMID 24809838, PMID 27188385, PMID 27454663, PMID 28455599, PMID 30409186, PMID 32467512, PMID 32500569, PMID 34086350, PMID 37236666, PMID 41062134
2015 (1)