11 completed, 4 terminated, 4 unknown, 2 active not recruiting. 10 Phase 2, 8 Not applicable, 5 Phase 1, 4 Phase 4.
Follow Antiemetics: new trials by email Literature Review of Antiemetics trials Research Report on Antiemetics
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| TRANSCUTANEOUS ELECTRICAL ACUPOINT STIMULATION FOR CISPLATIN- CHEMOTHERAPY INDUCED NAUSEA AND VOMITING Transcutaneous electrical nerve stimulation, Antiemetic - Nausea Post Chemotherapy, Vomiting | Not applicable | Completed | Cairo University | 34 | 2025-10-15 | 2026-04-03 |
| Sacituzumab Govitecan for Relapsed Ovarian, Endometrial, and Cervical Carcinomas Sacituzumab Govitecan, EKG, Brain MRI - Recurrent Platinum Resistant Epithelial Ovarian Carcinoma, Recurrent Epithelial Endometrial Carcinoma | Phase 2 | Terminated | National Cancer Institute (NCI) | 2 | 2025-06-09 | 2026-01-21 |
| A Comparison Between Palonosetron Versus Granisetron as PONV Prophylaxis in Scoliotic Patients Undergoing Spine Surgery Palonosetron (Group P), Granisetron (Group G) - Postoperative Nausea and Vomiting, Scoliosis | Phase 4 | Completed | University of Malaya | 74 | 2025-01-06 | 2026-08-20 |
| Effect of Kinesiotape on Emesis in Pregnant Women Antiemetic Drug, Vitamin B6, Home care advice - Emesis Pregnancy | Not applicable | Not yet recruiting | Cairo University | 50 | 2024-10-07 | 2024-10-08 |
| NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer. [68Ga]Ga-PSMA-11, [68Ga]GA-DOTA-TATE, [68Ga]Ga-NeoB - Metastatic Neuroendocrine Prostate Cancer | Phase 1 | Active not recruiting | Novartis Pharmaceuticals | 31 | 2024-07-29 | 2026-10-15 |
| Safety and Efficacy of MK-1200 in Participants With Advanced Solid Tumors (MK-1200-002) MK-1200, Antiemetic - Advanced Solid Tumors | Phase 1 / Phase 2 | Completed | Merck Sharp & Dohme LLC | 13 | 2024-02-28 | 2026-06-05 |
| Clinical Study Protocol of Maintenance Therapy With Venetoclax in Elderly Patients With AML in First Complete Remission Venclexta 100 MG Oral Tablet - Acute Myeloid Leukemia | Not applicable | Recruiting | The First Affiliated Hospital with Nanjing Medical University | 100 | 2023-04-12 | 2023-06-18 |
| 131I-Omburtamab, in Recurrent Medulloblastoma and Ependymoma Irinotecan, Temozolomide, Bevacizumab - Recurrent Medulloblastoma, Recurrent Ependymoma | Phase 2 | Active not recruiting | Pediatric Brain Tumor Consortium | 62 | 2022-04-04 | 2026-07-28 |
| Influence of Hypnoacupuncture on Early Perioperative Recovery ACUPUNCTURE, ANTIEMETICS, NOTHING - Postoperative Nausea and Vomiting, Acute Postoperative Pain | Not applicable | Completed | University Medical Centre Ljubljana | 60 | 2021-05-01 | 2022-11-08 |
| A Trial of the Safety and Immunogenicity of the COVID-19 Vaccine (mRNA-1273) in Participants With Hematologic Malignancies and Various Regimens of Immunosuppression, and in Participants With Solid Tumors on PD1/PDL1 Inhibitor Therapy Messenger ribonucleic acid (mRNA)-1273 Vaccine, Messenger ribonucleic acid (mRNA)-1273 Vaccine Booster, ECG - Solid Tumor Malignancy, Hematologic Malignancy | Phase 2 | Completed | National Cancer Institute (NCI) | 19 | 2021-04-28 | 2024-08-27 |
| The Effects of Acupuncture Against Postoperative Nausea and Vomit After Laparoscopic Cholecystectomy Acupuncture Needles, Antiemetic Drug - Postoperative Nausea, Postoperative Vomiting | Not applicable | Completed | University of West Attica | 100 | 2020-10-07 | 2021-02-18 |
| Induction Chemotherapy for MRF-negative, Moderate-risk, Resectable Middle and Low Rectal Cancer Oxaliplatin and capecitabine, Total Mesorectal Excision - Rectal Cancer | Phase 2 | Unknown | Peking University Cancer Hospital & Institute | 119 | 2019-03-01 | 2020-03-05 |
| Does Low Flow Anesthesia Reduce Postanaesthetic Emergence Agitation? Analgesics, Antiemetics - Agitated; State, Acute Reaction to Stress | Phase 4 | Completed | Sakarya University | 60 | 2018-06-01 | 2020-03-18 |
| CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies CD19/CD22 CAR T-Cells, Fludarabine, Cyclophosphamide - Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, B Cell | Phase 1 | Completed | National Cancer Institute (NCI) | 54 | 2018-03-26 | 2025-06-04 |
| Selinexor Plus High-Dose Melphalan (HDM) Before Autologous Hematopoietic Cell Transplantation for Multiple Myeloma Selinexor, Melphalan, Dexamethasone - Multiple Myeloma | Phase 1 / Phase 2 | Completed | H. Lee Moffitt Cancer Center and Research Institute | 22 | 2017-07-20 | 2022-11-04 |
| Study to Evaluate the Safety and Preliminary Efficacy of 177Lu-OPS201 in NETs Satoreotide tetraxetan, Amino acid solution, Antiemetic - Neuroendocrine Tumors | Phase 1 / Phase 2 | Terminated | Ipsen | 40 | 2017-03-06 | 2023-07-19 |
| Cabazitaxel in mCRPC Patients With AR-V7 Positive Circulating Tumor Cells (CTCs) Cabazitaxel, Antihistamine, Corticosteroid - Circulating Tumor Cell, Metastatic Prostate Cancer | Phase 2 | Unknown | Erasmus Medical Center | 140 | 2017-02-21 | 2021-08-20 |
| Acupuncture for Postoperative Nausea and Vomiting in Patients Undergoing Colorectal Surgery High-dose acupuncture with intravenous infusion of ramosetron, P6 stimulation with intravenous infusion of ramosetron, Intravenous infusion of ramosetron - Postoperative Nausea and Vomiting, Colorectal Neoplasms | Not applicable | Completed | Pusan National University Yangsan Hospital | 60 | 2015-07-01 | 2024-08-12 |
| Post-operative Nausea Vomiting in Laparoscopic Cholecystectomy ramosetron, ondansetron, dexamethasone - Postoperative Nausea and Vomiting | Phase 4 | Unknown | Government Medical College, Haldwani | 100 | 2015-07-01 | 2016-06-17 |
| Comparative Effect Study Between Distal-proximal Point Association and Local Distribution Point Association in Chemotherapy-induced Nausea and Vomiting only antiemetic (Ramosetron, Tropisetron and dexamethasone), Matching points ST36+CV12 plus antiemetic drug, Matching points PC6+CV12 plus antiemetic drug - Chemotherapy-induced Nausea and Vomiting | Not applicable | Unknown | Tianjin University of Traditional Chinese Medicine | 240 | 2015-06-01 | 2015-06-23 |
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Postoperative Nausea and Vomiting (5) · Lymphoma (3) · Vomiting (3) · Lymphoma, Non-Hodgkin (2) · Multiple Myeloma (2) · Bulbo-Spinal Atrophy, X-Linked (1) · Burkitt Lymphoma (1) · Carcinoma, Non-Small-Cell Lung (1) · Chondrosarcoma (1) · Colorectal Neoplasms (1) · Ependymoma (1) · Hematologic Neoplasms (1) · Leukemia (1) · Leukemia, B-Cell (1) · Leukemia, Myeloid, Acute (1)
National Cancer Institute (NCI) (3) · Cairo University (2) · AEterna Zentaris (1) · Australasian Leukaemia and Lymphoma Group (1) · Erasmus Medical Center (1) · Government Medical College, Haldwani (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · Indiana University (1) · Ipsen (1) · Merck Sharp & Dohme LLC (1) · Novartis Pharmaceuticals (1) · Pediatric Brain Tumor Consortium (1) · Peking University Cancer Hospital & Institute (1) · Pusan National University Yangsan Hospital (1) · Sakarya University (1)
United States (10) · China (4) · Australia (2) · Egypt (2) · France (2) · South Korea (2) · United Kingdom (2) · Austria (1) · Canada (1) · Chile (1) · Denmark (1) · Germany (1) · Greece (1) · India (1) · Israel (1)
Ahmad Tarhini, MD (1) · Aiwen Wu (1) · Ali Fuat Erdem, Professor (1) · Andrew Grigg, Professor (1) · Azza Barmoud Nashed Kassab, PhD (1) · Dejka Araujo, MD (1) · Hee Young Kim, PhD (1) · James Gulley, M.D. (1) · Kevin C Conlon, M.D. (1) · Malik Nouri, MD (1) · Matthias Karajannis, MD, MS (1) · Mohd Shahnaz Hasan, MAnaes, MBBS (1)
PMID 15915040, PMID 16306743, PMID 27188385, PMID 27454663, PMID 27821107, PMID 28052910, PMID 28455599, PMID 30409186, PMID 32467512, PMID 33023948, PMID 34086350, PMID 34687939, PMID 34889384, PMID 35605184, PMID 37486616, PMID 37721581, PMID 38376944, PMID 38528164, PMID 42248607
2023 (2), 2015 (1), UM1CA081457 (1)