6818 completed, 1397 unknown, 778 recruiting, 608 terminated. 3453 Not applicable, 1443 Phase 2, 1289 Phase 3, 937 Phase 4, 817 Phase 1.
Follow Lung Diseases, Obstructive: new trials by email Literature Review of Lung Diseases, Obstructive trials Research Report on Lung Diseases, Obstructive
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Developing an Intervention to Optimize Virtual Care Adoption for COPD Management VC-OPTIONS - Chronic Obstructive Pulmonary Disease | Not applicable | Not yet recruiting | VA Office of Research and Development | 40 | 2027-09-02 | 2026-09-29 |
| Remote Intervention Versus Routine Monitoring in COPD Patients With Chronic Hypercapnia Receiving Home Non-invasive Respiratory Support Remote Management, Remote Monitoring Only - COPD (Chronic Obstructive Pulmonary Disease), Acute Exacerbation of COPD | Not applicable | Not yet recruiting | Sir Run Run Shaw Hospital | 236 | 2027-08-01 | 2026-08-06 |
| RSV Vaccination to Reduce Recurrent AECOPD RSV vaccination (Arexvy, GlaxoSmithKline) - COPD, RSV | Phase 4 | Not yet recruiting | Chinese University of Hong Kong | 320 | 2027-07-01 | 2026-04-13 |
| cfMSC Stem Cell Therapy Targeting COPD clonal fetal MSCs - Chronic Obstructive Pulmonary Disease (COPD) | Phase 1 / Phase 2 | Not yet recruiting | Shenzhen Geno-Immune Medical Institute | 30 | 2027-06-30 | 2026-08-27 |
| Effect of Linvemastat in Patients With Partially Controlled Asthma (syMMPonia) linvemastat, Placebo - Asthma (Diagnosis), Pulmonary Function | Phase 2 | Not yet recruiting | Foresee Pharmaceuticals Co., Ltd. | 135 | 2027-03-01 | 2026-07-20 |
| Mindfulness Intervention to Reduce Patient Reported Symptoms in Patients With Chronic Graft-Versus-Host Disease Biospecimen Collection, Mindfulness Relaxation, Survey Administration - Chronic Graft Versus Host Disease, Hematopoietic and Lymphatic System Neoplasm | Not applicable | Recruiting | City of Hope Medical Center | 17 | 2027-03-01 | 2026-10-16 |
| Preventing Childhood Asthma Using Prophylactic House Dust Mite Allergen Immunotherapy HDM sublingual Immunotherapy, Placebo - Asthma, Allergy | Phase 2 | Withdrawn | Boston Children's Hospital | 2027-02-01 | 2024-11-26 | |
| Prevent Wheeze Trial Dexamethasone 0.6 mg/kilogram body weight single dose, Placebo - Lower Respiratory Tract Infection (LRTI), Recurrent Wheezing | Phase 4 | Not yet recruiting | Norwegian University of Science and Technology | 486 | 2027-02-01 | 2026-10-05 |
| Comparative Effectiveness of Roflumilast and Azithromycin in Reducing Exacerbations in Severe Chronic Obstructive Pulmonary Disease ( COPD ) Patients With Chronic Bronchitis Phenotype Roflumilast Oral Tablet, Azithromycin 250 mg - Chronic Obstructive Pulmonary Disease With Exacerbation | Phase 4 | Not yet recruiting | Sidra Aziz | 70 | 2027-02-01 | 2026-08-31 |
| Study of Fluticasone/Formoterol/Glycopyrronium for the Treatment Chronic Obstructive Pulmonary Disease (TRIPLAR) Fluticasone 250mcg/Formoterol 12mcg/Glycopyrronium 25mcg, Comparator - Trimbow® - Chronic Obstructive Pulmonary Disease | Phase 3 | Not yet recruiting | Eurofarma Laboratorios S.A. | 1252 | 2027-01-30 | 2026-10-26 |
| Educational Needs of Patients With Severe Asthma on Targeted Immunotherapies Initial assesment interwiew, Intake Interview with the Patient - Severe Asthma | Not yet recruiting | University Hospital, Angers | 20 | 2027-01-04 | 2026-10-02 | |
| Repeat Treatment With Metered Cryospray in Patients With Chronic Obstructive Pulmonary Disease With Chronic Bronchitis Metered cryospray (MCS) - COPD (Chronic Obstructive Pulmonary Disease), Chronic Bronchitis | Not applicable | Not yet recruiting | CSA Medical, Inc. | 10 | 2027-01-02 | 2026-10-05 |
| Pulmonary Rehabilitation Frequency in COPD Patients Pulmonary Rehabilitation - COPD, COPD (Chronic Obstructive Pulmonary Disease) | Not applicable | Not yet recruiting | Hospital Universitario Fundación Alcorcón | 158 | 2027-01-01 | 2026-05-08 |
| Efficacy and Safety of Slow Release Dehydroepiandrosterone (DHEA ) Slow Release DHEA, Placebo - Asthma | Phase 2 | Not yet recruiting | Indiana University | 30 | 2027-01-01 | 2026-02-27 |
| A Study of the Effect of a Nurse Navigator Program on High Risk Patients Nurse Navigator Program - Patient Readmission, Arthroplasty, Replacement, Knee | Not applicable | Not yet recruiting | Mayo Clinic | 300 | 2027-01-01 | 2026-03-19 |
| Nebulized Ketamine for Severe Asthma Attacks in Children Ketamine (1 mg/kg), Placebo - Asthma Acute, Exacerbation of Allergic Asthma | Phase 2 | Not yet recruiting | Sultan Qaboos University | 60 | 2027-01-01 | 2026-07-27 |
| Multimodal Stewardship Programme to Improve Antibiotic Prescribing for Children With Lower Respiratory Tract Infections PRACTICE-LRTI multimodal antimicrobial stewardship programme - Bronchitis, Acute, Community-acquired Pneumonia | Not applicable | Not yet recruiting | Tampere University | 50000 | 2027-01-01 | 2026-10-26 |
| Sustained Asthma Remission and Reduced Relapse Using a Comprehensive Management Strategy (SARRE-COMS) Comprehensive Biomarker-Guided Management Strategy, Standard of Care - Asthma (Diagnosis) | Not applicable | Not yet recruiting | Hana Serajeddini | 50 | 2026-12-02 | 2026-09-25 |
| Allergy, Asthma, and Atopic Eczema in Finland No intervention, No Intervention: Observational Cohort - Asthma, Asthma in Children | Not yet recruiting | Tampere University | 1200000 | 2026-12-01 | 2026-10-15 | |
| The Effect of Inhaled Nitric Oxide on Pulmonary Gas-exchange in COPD Inhaled Nitric Oxide, Placebo - Chronic Obstructive Pulmonary Disease | Phase 1 / Phase 2 | Not yet recruiting | University of Alberta | 80 | 2026-12-01 | 2026-07-08 |
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Pulmonary Disease, Chronic Obstructive (5328) · Asthma (4460) · Bronchiolitis Obliterans Syndrome (703) · Lung Diseases (341) · Emphysema (301) · Dyspnea (296) · Motor Activity (287) · Bronchiolitis (261) · Heart Failure (223) · Bronchitis, Chronic (201) · Hypersensitivity (190) · Bronchitis (146) · Diabetes Mellitus (143) · Inflammation (137)
Respiratory Tract Diseases (10459) · Lung Diseases (10220) · Pathological Conditions, Signs and Symptoms (6237) · Bronchial Diseases (5770) · Pathologic Processes (5760) · Disease Attributes (5549) · Chronic Disease (5441) · Immune System Diseases (5208) · Hypersensitivity, Immediate (4471) · Respiratory Hypersensitivity (4444) · Hypersensitivity (4314) · Bronchitis (1222) · Infections (966) · Signs and Symptoms (956)
Tiotropium Bromide (274) · Formoterol Fumarate (236) · Fluticasone (234) · Budesonide (229) · Albuterol (227) · Salmeterol Xinafoate (172) · montelukast (153) · Fluticasone-Salmeterol Drug Combination (134) · Budesonide, Formoterol Fumarate Drug Combination (107) · Exercise (103) · Beclomethasone (97) · Glycopyrrolate (91) · indacaterol (90) · Standard of Care (71) · Omalizumab (70)
AstraZeneca (528) · GlaxoSmithKline (522) · Boehringer Ingelheim (292) · Novartis Pharmaceuticals (178) · Chiesi Farmaceutici S.p.A. (117) · National Heart, Lung, and Blood Institute (NHLBI) (102) · Riphah International University (91) · Imperial College London (85) · Organon and Co (66) · Assistance Publique - Hôpitaux de Paris (64) · Sanofi (62) · Laval University (57) · Pfizer (56) · Johns Hopkins University (54) · Brigham and Women's Hospital (52)
United States (3147) · United Kingdom (1133) · Germany (953) · Canada (872) · France (781) · China (645) · Spain (572) · Italy (499) · Poland (446) · Netherlands (437) · Turkey (Türkiye) (403) · Belgium (377) · Denmark (363) · South Korea (324) · Russia (311)
Louis-Philippe Boulet, MD (21) · Dave Singh, MD (19) · Esther Garcia, MD (19)
PMID 36472162, PMID 33511633, PMID 27881132, PMID 34495549, PMID 37010196, PMID 32943047, PMID 35815359, PMID 42149813, PMID 37542951, PMID 39393433, PMID 31319851, PMID 29400693, PMID 35691614, PMID 42551404, PMID 17507545, PMID 24314123, PMID 33217063, PMID 35514131, PMID 38127464, PMID 39423760, PMID 12091180, PMID 19720809, PMID 24127811, PMID 26704701, PMID 30954640, PMID 32816215, PMID 33124005, PMID 33305842, PMID 10377201, PMID 16055882, PMID 1759018, PMID 17951621, PMID 20102307, PMID 22329608, PMID 23497334, PMID 24184147, PMID 25066329, PMID 25359355, PMID 25496316, PMID 25918120, PMID 28065396, PMID 28419462, PMID 29174062, PMID 29536781, PMID 30077810, PMID 32180164, PMID 32462607, PMID 32671684, PMID 32848381, PMID 33152467
2015 (52), 2009 (47), 2017 (43), 2014 (40), 2016 (39), 2023 (37), 2018 (36), 2019 (32), 2025 (30), 2008 (28), U10HL098115 (8), 2005 (7), U10HL074212 (6), P01HL107202 (5), R01HL082480 (5)