12 completed, 3 unknown, 2 terminated, 1 active not recruiting. 20 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 20 | Completed 12, Unknown 3, Terminated 2, Active not recruiting 1, Recruiting 1, Withdrawn 1 |
Follow Respiratory Failure: new trials by email Literature Review of Respiratory Failure trials Research Report on Respiratory Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of Gas Exchange Between Two Invasive Mechanical Ventilation Modes in Children Respiratory support a, Respiratory support b - Respiratory Failure | Phase 4 | Completed | University Children's Hospital, Zurich | 59 | 2024-01-15 | 2024-12-13 |
| The Effect of an Additional Pre-extubational Loading Dose of Caffeine-citrate Caffeine citrate - Apnea of Prematurity, Premature Birth | Phase 4 | Recruiting | Semmelweis University | 226 | 2023-12-21 | 2024-05-06 |
| High-dose L-Carnitine and Diaphragmatic Function Assessed by Ultrasonography in Patients With Respiratory Failure. L Carnitine ( low dose), L-Carnitine ( high dose) - Respiratory Failure | Phase 4 | Completed | Ain Shams University | 60 | 2022-04-15 | 2022-10-17 |
| Use of Dexmedetomidine in Light to Moderate Sedation in the Patient in the Palliative Situation of a Sars-cov-2 / COVID-19 Infection Treatment with Dexmedetomidine - COVID-19 Infection, Sars-cov-2 | Phase 4 | Withdrawn | University Hospital, Limoges | 2020-04-20 | 2020-09-02 | |
| Rapid Atrial Fibrillation Treatment Strategy Amiodarone in Parenteral Dosage Form, Amiodarone Pill, Direct Current Cardioversion (DCC) - New Onset Atrial Fibrillation, Sepsis | Phase 4 | Unknown | Our Lady of the Lake Hospital | 40 | 2019-09-16 | 2019-09-17 |
| Avoiding Neuromuscular Blockers to Reduce Complications Neuromuscular Blocking Agents, Anesthetic Adjuncts - Respiratory Failure, Respiratory Infection | Phase 4 | Terminated | Beth Israel Deaconess Medical Center | 3 | 2019-08-07 | 2026-06-04 |
| Pan-genotypic Direct Acting Antiviral Therapy in Donor HCV-positive to Recipient HCV-negative Lung Transplant Clinically prescribed direct acting antiviral (Mavyret or Epclusa) HCV treatment for 8 weeks - Respiratory Failure, Hepatitis C | Phase 4 | Terminated | Massachusetts General Hospital | 19 | 2019-02-05 | 2023-04-25 |
| Veno-venous Extracorporeal Membrane Oxygenation (VV-ECMO) Heparin Study subcutaneous heparin anticoagulation - ECMO, Heparin | Phase 4 | Active not recruiting | Baylor Research Institute | 100 | 2018-10-10 | 2026-01-30 |
| The Study of Pharmacokinetics and Pharmacodynamics of Cisatracurium cisatracurium - Critical Illness, Respiratory Distress Syndrome, Adult | Phase 4 | Completed | Mahidol University | 10 | 2017-12-15 | 2019-03-06 |
| Checklists and Upright Positioning in Endotracheal Intubation of Critically Ill Patients (Check-UP) Trial Written Checklist, Head of Bed Up - Respiratory Failure | Phase 4 | Completed | Vanderbilt University | 260 | 2015-07-01 | 2016-09-19 |
| A Trial Comparing SGC and Conventional Empiric Treatment for Glucose Control in Critically Ill Patients With Mechanical Ventilation in ICU conventional empirical glycemic control, SGC directed glycemic control - Hyperglycemia, Respiratory Failure | Phase 4 | Unknown | Peking Union Medical College Hospital | 46 | 2014-10-01 | 2015-07-08 |
| Study of Sedative Medications in Patients With Severe Infection and Respiratory Failure Propofol, Dexmedetomidine, Fentanyl - Sepsis, Respiratory Failure | Phase 4 | Completed | Texas Tech University Health Sciences Center | 36 | 2014-08-01 | 2020-03-02 |
| Brain Oxygenation and Function of Preterm Newborns During Administration of Two Different Surfactant Preparations Poractant alfa instillation, Beractant instillation - Respiratory Distress Syndrome, Newborn, Respiratory Failure | Phase 4 | Completed | Poznan University of Medical Sciences | 22 | 2013-03-03 | 2020-03-05 |
| Closed Loop Ventilation Strategy in Intensive Care Unit (ICU) Patients Adaptive Support Ventilation, Pressure Controlled Ventilation - Respiratory Failure, All Intubated Patients | Phase 4 | Completed | Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital | 229 | 2012-04-01 | 2014-03-06 |
| Prevention of Pressure Ulcers in Patients Under Non-Invasive Mechanical Ventilation Allevyn Thin®, Askina Transorbent Border®, Linovera® - Respiratory Failure | Phase 4 | Completed | B. Braun Medical SA | 152 | 2012-02-01 | 2015-08-18 |
| Proportional Assist Ventilation (PAV) in Early Stage of Critically Ill Patients Mechanical ventilation mode (PAV+ vs. ACV) - Respiratory Failure, Mechanical Ventilation | Phase 4 | Completed | Althaia Xarxa Assistencial Universitària de Manresa | 110 | 2010-09-01 | 2012-11-27 |
| Comparison of the Efficacy for Stress Ulcer Prophylaxis Between the Patients Received Lansoprazole OD and Control Group Weaning From Mechanical Ventilator in Respiratory Care Center: a Randomized Control Trial lansoprazole OD, placebo - Respiratory Failure | Phase 4 | Completed | Far Eastern Memorial Hospital | 120 | 2009-06-01 | 2013-01-08 |
| Inspiratory Muscle Training in Hypercapnic COPD inspiratory muscle training - COPD, Respiratory Failure | Phase 4 | Unknown | Krankenhaus Kloster Grafschaft | 40 | 2006-02-01 | 2006-08-21 |
| Inhaled Nitric Oxide by Oxygen Hood in Neonates inhaled Nitric Oxide, Oxygen (>90% by hood) - standard therapy - Respiratory Failure, Infant | Phase 4 | Completed | University of Alabama at Birmingham | 8 | 1999-03-01 | 2008-08-12 |
| Chronic Obstructive Pulmonary Disease and Weaning From Mechanical Ventilation in Difficult to Wean Patients Weaning from mechanical ventilation - Respiratory Failure | Phase 4 | Completed | Dr. Josip Benčević General Hospital | 2006-10-26 |
Respiratory Insufficiency (20) · Critical Illness (2) · Pulmonary Disease, Chronic Obstructive (2) · Respiratory Aspiration (2) · Sepsis (2) · Apnea (1) · Bronchial Spasm (1) · COVID-19 (1) · Hepatitis C (1) · Hyperglycemia (1) · Hypoxia (1) · Infections (1) · Lung Diseases (1) · Microcephaly, Primary Autosomal Recessive, 6 (1) · Paralysis (1)
Respiration Disorders (20) · Respiratory Tract Diseases (20) · Pathological Conditions, Signs and Symptoms (9) · Lung Diseases (7) · Pathologic Processes (7) · Disease Attributes (4) · Infections (4) · Signs and Symptoms (4) · Chronic Disease (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Infant, Newborn, Diseases (2) · Inflammation (2) · Lung Diseases, Obstructive (2) · Nervous System Diseases (2) · Neurologic Manifestations (2)
Dexmedetomidine (3) · Propofol (2) · Amiodarone (1) · Analgesics, Opioid (1) · Carnitine (1) · Checklist (1) · Electric Countershock (1) · Fentanyl (1) · Injections (1) · Interactive Ventilatory Support (1) · Ketamine (1) · Neuromuscular Blocking Agents (1) · Nitric Oxide (1) · Oxygen (1) · Patient Positioning (1)
Ain Shams University (1) · Althaia Xarxa Assistencial Universitària de Manresa (1) · B. Braun Medical SA (1) · Baylor Research Institute (1) · Beth Israel Deaconess Medical Center (1) · Dr. Josip Benčević General Hospital (1) · Far Eastern Memorial Hospital (1) · Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital (1) · Krankenhaus Kloster Grafschaft (1) · Mahidol University (1) · Massachusetts General Hospital (1) · Our Lady of the Lake Hospital (1) · Peking Union Medical College Hospital (1) · Poznan University of Medical Sciences (1) · Semmelweis University (1)
United States (7) · Spain (2) · China (1) · Croatia (1) · Egypt (1) · France (1) · Germany (1) · Hungary (1) · Poland (1) · Switzerland (1) · Taiwan (1) · Thailand (1) · Turkey (Türkiye) (1)
Bin Du, Dr (1) · Cenk Kirakli, MD (1) · Chu C Lin, MD (1) · Dieter Koehler, Prof. Dr. (1) · Dominic Dellweg, M.D. (1) · Gary Schwartz, MD (1) · Hollis R O'Neal, MD (1) · Kenneth Nugent, MD (1) · Maximilian S Schaefer, MD (1) · Namasivayam Ambalavanan, MD (1) · Rafael Fernandez, M.D. (1) · Raymond T Chung, MD (1) · Rebeca Mozun, MD PhD (1)
PMID 10712328, PMID 16394778, PMID 25742308, PMID 27855722, PMID 28487139, PMID 28836546, PMID 28917549, PMID 35065599, PMID 39800404, PMID 39804861