9 completed, 3 terminated, 2 not yet recruiting, 1 active not recruiting. 6 Phase 4, 3 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 6 | Completed 4, Terminated 2 |
| Phase 2 | 3 | Active not recruiting 1, Completed 1, Withdrawn 1 |
| Phase 3 | 2 | Not yet recruiting 1, Terminated 1 |
| Phase 1 | 1 | Completed 1 |
Follow Neuromuscular Blocking Agents: new trials by email Literature Review of Neuromuscular Blocking Agents trials Research Report on Neuromuscular Blocking Agents
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Associations Between Time to Reduction and Complications in Patients With Dislocated Total Hip Arthroplasty Time in minutes from admission to closed reduction - Closed Reduction, Arthroplasty, Replacement, Hip | Not yet recruiting | Nordsjaellands Hospital | 3700 | 2025-08-20 | 2025-08-20 | |
| Management of Neuromuscular Blocking Agents and Their Antagonism Neuromuscular Blocking Agent - Neuromuscular Blocking Agents, Neuromuscular Monitoring | Unknown | Erasme University Hospital | 3000 | 2024-04-17 | 2024-04-19 | |
| Muscle Relaxation for Pediatric Adenotonsillectomy Rocuronium, Sugammadex, Anesthesia without neuromuscular blockade - Tonsillectomy | Phase 4 | Completed | University of Texas Southwestern Medical Center | 172 | 2024-04-10 | 2025-07-28 |
| Individualized Positive End-expiratory Pressure Guided by End-expiratory Lung Volume in the Acute Respiratory Distress Syndrome Invasive Mechanical ventilation, Neuromuscular Blocking Agents, Prone positioning - Respiratory Distress Syndrome, Adult | Phase 3 | Terminated | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 18 | 2022-11-01 | 2025-09-30 |
| Trial of Therapeutic Hypothermia in Patients With ARDS Hypothermia, Neuromuscular Blocking Agents, Standard of care - Respiratory Distress Syndrome, Adult | Phase 2 | Active not recruiting | University of Maryland, Baltimore | 340 | 2021-06-29 | 2026-09-09 |
| Paediatric Ards Neuromuscular Blockade Study Neuromuscular Blocking Agents, Isotonic saline - ARDS | Phase 4 | Terminated | University Medical Center Groningen | 3 | 2019-12-01 | 2025-02-07 |
| Neuromuscular Blockade in the Intentive Care Unit, an Observational Study. Neuromuscular Blocking Agents - Critical Care, Mechanical Ventilation | Completed | French Society for Intensive Care | 282 | 2019-11-02 | 2021-12-16 | |
| Comparison of Sugammadex and Neostigmine During PACU Stay Neuromuscular Blocking Agents - Neuromuscular Blockade | Phase 3 | Not yet recruiting | University of South Florida | 50 | 2019-10-15 | 2019-09-19 |
| Avoiding Neuromuscular Blockers to Reduce Complications Neuromuscular Blocking Agents, Anesthetic Adjuncts - Respiratory Failure, Respiratory Infection | Phase 4 | Terminated | Beth Israel Deaconess Medical Center | 3 | 2019-08-07 | 2026-06-04 |
| The Effect of Deep Neuromuscular Block and Reversal With Sugammadex on Surgical Conditions and Perioperative Morbidity in Shoulder Surgery Using a Deltopectoral Approach Deep neuromuscular block, Moderate neuromuscular block, Neuromuscular Blocking Agents and reversing agents - Shoulder Pain, Anesthesia | Phase 4 | Completed | Universitaire Ziekenhuizen KU Leuven | 52 | 2018-12-18 | 2024-12-12 |
| Provider Variability in the Use of Neuromuscular Blocking Drugs and Reversal Neuromuscular blocking agents - Neuromuscular Blockade, Residual Curarisation, Postoperative | Completed | Beth Israel Deaconess Medical Center | 265537 | 2018-06-29 | 2021-08-25 | |
| Pilot RCT of Therapeutic Hypothermia Plus Neuromuscular Blockade in COVID-19 Patients With ARDS Hypothermia, Neuromuscular Blocking Agents, Standard of Care - Respiratory Distress Syndrome, Adult, Sars-CoV2 | Phase 2 | Withdrawn | University of Maryland, Baltimore | 2018-05-01 | 2021-04-30 | |
| Deep vs Moderate Neuromuscular Blockade in Day Case Laparoscopic Cholecystectomy. Rocuronium Bromide - Muscle Relaxation | Phase 4 | Completed | Wahba bakhet | 80 | 2017-04-01 | 2019-10-29 |
| Myorelaxation Practice in Paediatric Anesthesia Neuromuscular Blocking Agent - Neuromuscular Blockade | Completed | Brno University Hospital | 1650 | 2017-03-05 | 2018-11-19 | |
| Deep NMB in Ambulatory Gynecological Laparoscopy Rocuronium, Rocuronium bromide - Muscle Relaxation | Phase 4 | Completed | Wahba bakhet | 80 | 2016-12-01 | 2019-12-10 |
| Strategy of UltraProtective Lung Ventilation With Extracorporeal CO2 Removal for New-Onset Moderate to seVere ARDS ECCO2R will be initiated during the 2-hour run-in time, Neuromuscular blocking agents (NMBA), Ventilation - Moderate Acute Respiratory Distress Syndrome | Phase 1 / Phase 2 | Completed | European Society of Intensive Care Medicine | 95 | 2015-11-01 | 2017-08-04 |
| Incidence of Incomplete Postoperative Neuromuscular Recovery From Anesthesia (P07535)(Completed) Neuromuscular Blocking Agent (NMBA) - Neuromuscular Blockade | Completed | Merck Sharp & Dohme LLC | 350 | 2010-07-01 | 2015-10-14 |
Respiratory Distress Syndrome (3) · Acute Lung Injury (1) · Bronchial Spasm (1) · COVID-19 (1) · Delayed Emergence from Anesthesia (1) · Muscle Hypotonia (1) · Pneumonia (1) · Pneumonia, Aspiration (1) · Pulmonary Atelectasis (1) · Respiratory Insufficiency (1) · Respiratory Tract Infections (1) · Shoulder Pain (1) · Sleep Apnea Syndromes (1) · Sleep Apnea, Obstructive (1) · Snoring (1)
Beth Israel Deaconess Medical Center (2) · University of Maryland, Baltimore (2) · Wahba bakhet (2) · Brno University Hospital (1) · Erasme University Hospital (1) · European Society of Intensive Care Medicine (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · French Society for Intensive Care (1) · Merck Sharp & Dohme LLC (1) · Nordsjaellands Hospital (1) · Universitaire Ziekenhuizen KU Leuven (1) · University Medical Center Groningen (1) · University of South Florida (1) · University of Texas Southwestern Medical Center (1)
United States (6) · Belgium (3) · Czechia (1) · Denmark (1) · Egypt (1) · France (1) · Italy (1) · Kuwait (1) · Netherlands (1)
Jeffrey D Hasday, MD (2) · Domenico Luca Grieco, MD (1) · Enrico M Camporesi, MD (1) · Harm Hoekstra, Prof. Dr. (1) · Maha Balouch, MA (1) · Massimo Antonelli, MD (1) · Maximilian S Schaefer, MD (1) · Michael Albrink, MD (1) · Philipp Fassbender, MD (1) · Proshad Efune, MD (1)
PMID 23344123, PMID 30790030, PMID 33784416, PMID 35057852, PMID 35101098, PMID 41123780, PMID 42107449