35 completed, 3 recruiting, 3 unknown, 2 terminated. 10 Not applicable, 7 Phase 2, 7 Phase 3, 5 Phase 4, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 8, Recruiting 1, Unknown 1 |
| Phase 2 | 7 | Completed 7 |
| Phase 3 | 7 | Completed 5, Recruiting 1, Terminated 1 |
| Phase 4 | 5 | Completed 4, Terminated 1 |
| Phase 1 | 2 | Completed 2 |
Follow Bronchial Spasm: new trials by email Literature Review of Bronchial Spasm trials Research Report on Bronchial Spasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Compare Safety of 4 Weeks Exposure to Propellants Hydrofluoroalkane 1,1-difluoroethane (HFA-152a) and HFA-1,1,1,2-tetrafluoroethane (134a) HFA-152a, HFA-134a - Asthma | Phase 3 | Recruiting | GlaxoSmithKline | 110 | 2026-09-01 | 2026-09-30 |
| Perioperative Respiratory Adverse Events in Cleft Lip and Palate Surgery: Incidence, Risk Factors, and Clinical Scoring Standard General Anesthesia per Institutional Protocol - Cleft Palate, Cleft Lip | Not yet recruiting | Marmara University Pendik Training and Research Hospital | 150 | 2026-06-27 | 2026-06-16 | |
| Longitudinal Phenotyping and Endotyping Study in Adult Patients With Mild, Moderate, or Severe Asthma Asthma (Diagnosis) | Recruiting | Hvivo | 250 | 2025-08-08 | 2025-09-24 | |
| Intraoperative Paravertebral Block and Postoperative Complications Paravertebral Block (PVB) - Video-assisted Thoracoscopic Surgery (VATS), Lung Cancer (Diagnosis) | Not applicable | Recruiting | Tongji Hospital | 500 | 2025-03-25 | 2025-10-08 |
| A Study to Investigate the Effects of PT027 (Budesonide/Albuterol Sulfate) Metered-dose Inhaler Compared With Placebo on Exercise-Induced Bronchoconstriction in Adult Patients With Asthma Budesonide/albuterol metered-dose inhaler 160/180 μg, Placebo metered-dose inhaler - Asthma, Exercise-Induced | Phase 3 | Completed | AstraZeneca | 64 | 2023-12-22 | 2025-08-27 |
| Perioperative Vaping Complications Vaping, Complication of Anesthesia | Unknown | Navy Medical Center San Diego | 300 | 2023-07-28 | 2024-05-17 | |
| Study to Assess Bronchospasm Potentially Induced by Next-Generation Propellant vs HFA Propellant in an MDI in Participants With Well/Partially Controlled Asthma HFA MDI, HFO MDI - Asthma | Phase 3 | Completed | AstraZeneca | 52 | 2023-05-02 | 2026-02-06 |
| Wei Nasal Jet Tube vs Nasal Cannula Oxygen Support in Gastrointestinal Endoscopy Patients Wei Nasal Jet Tube, Nasal Cannula Oxygen Support - Supraglottic Airway Obstruction, Airway Complication of Anesthesia | Not applicable | Completed | Bezmialem Vakif University | 100 | 2023-03-30 | 2024-08-12 |
| INHALATION CHAMBER MANAGEMENT IN PEDIATRICS: EFFICACY OF AN EDUCATIONAL INTERVENTION IN PATIENTS DIAGNOSED WITH BRONCHOSPASM AND THEIR FAMILY CAREGIVERS. educational intervention - Bronchospasm | Not applicable | Completed | Puerta de Hierro University Hospital | 134 | 2023-01-10 | 2026-09-09 |
| Interest of Lidocaine in Children with Upper Airway Infection Undergoing General Anesthesia Lidocaine (drug), Saline (NaCl 0,9 %) (placebo) - Upper Respiratory Tract Infections, Perioperative Respiratory Complications | Phase 4 | Completed | Tunis University | 102 | 2023-01-02 | 2024-09-19 |
| Wei Nasal Jet Tube vs Gastro Laryngeal Tube in Endoscopic Retrograde Cholangiopancreatography Wei Nasal Jet Tube, Gastro Laryngeal Tube - Supraglottic Airway Efficiency, Airway Complication of Anesthesia | Not applicable | Completed | Bezmialem Vakif University | 114 | 2022-05-10 | 2022-09-15 |
| Bronchospasm During Anesthetic Induction: Study of Clinical Characteristics and Treatments Administered According to Etiology Bronchospasm | Completed | Central Hospital, Nancy, France | 31 | 2020-09-01 | 2021-08-27 | |
| Avoiding Neuromuscular Blockers to Reduce Complications Neuromuscular Blocking Agents, Anesthetic Adjuncts - Respiratory Failure, Respiratory Infection | Phase 4 | Terminated | Beth Israel Deaconess Medical Center | 3 | 2019-08-07 | 2026-06-04 |
| Comparing the Efficacy of Two Valved Holding Chambers in Acute Wheezing VHC 1, VHC 2 - Bronchitis Obstructive, Bronchiolitis; Obstruction | Not applicable | Completed | Tampere University | 80 | 2019-04-17 | 2026-01-29 |
| Efficacy and Safety of Continuous Infusion of Ketamine in Pediatric Intensive Care Unit (KISS Study) Analgesia, Ketamine Toxicity | Completed | Azienda Ospedaliera di Padova | 57 | 2019-04-01 | 2022-02-15 | |
| Virtual Teach-to-Goal Education vs. Brief Education for Children Virtual Teach to Goal, Brief Intervention - Asthma, Bronchospasm | Not applicable | Completed | University of Chicago | 70 | 2019-01-16 | 2021-04-29 |
| Change of Regional Ventilation During Spontaneous Breathing After Lung Surgery Perioperative pulmonary function tests - Pulmonary Infection, Respiratory Insufficiency | Completed | Wuerzburg University Hospital | 31 | 2016-06-01 | 2017-11-06 | |
| Driving Pressure And EFL in Adult Cardiac Surgery Respiratory Failure, Pneumothorax | Completed | Ospedale San Raffaele | 200 | 2015-11-01 | 2017-05-23 | |
| Ketamine Efficacy for Acute Severe Bronchospasm in ICU: MACANUDO Trial Ketamine, Fentanyl - Critical Illness, Asthma | Phase 2 / Phase 3 | Completed | Hospital Nossa Senhora da Conceicao | 45 | 2015-06-04 | 2024-05-21 |
| Perioperative Change of Regional Ventilation During Spontaneous Breathing Perioperative pulmonary function tests - Pulmonary Infection, Pleural Effusion | Completed | Wuerzburg University Hospital | 72 | 2015-01-01 | 2016-03-01 |
Showing 20 of 44. Sign in to see all of them.
Asthma (17) · Pulmonary Atelectasis (8) · Respiratory Insufficiency (8) · Pneumonia, Aspiration (6) · Pneumothorax (6) · Asthma, Exercise-Induced (4) · Cough (4) · Pleural Effusion (4) · Respiratory Tract Infections (4) · Bronchitis (3) · Dyspnea (3) · Laryngismus (3) · Pneumonia (3) · Pulmonary Disease, Chronic Obstructive (3)
Respiratory Tract Diseases (44) · Bronchial Diseases (43) · Lung Diseases (29) · Pathological Conditions, Signs and Symptoms (22) · Hypersensitivity, Immediate (20) · Immune System Diseases (20) · Lung Diseases, Obstructive (19) · Hypersensitivity (18) · Respiratory Hypersensitivity (17) · Respiration Disorders (16) · Signs and Symptoms (14) · Infections (13) · Pathologic Processes (11) · Signs and Symptoms, Respiratory (11) · Respiratory Tract Infections (9)
Albuterol (3) · Epinephrine (2) · Fluticasone-Salmeterol Drug Combination (2) · Ketamine (2) · Analgesics, Opioid (1) · Beclomethasone (1) · Budesonide (1) · Continuous Positive Airway Pressure (1) · Crisis Intervention (1) · Dexmedetomidine (1) · Early Intervention, Educational (1) · Fentanyl (1) · Fluticasone (1) · Inhalation (1) · Iron-Dextran Complex (1)
GlaxoSmithKline (6) · Amphastar Pharmaceuticals, Inc. (4) · AstraZeneca (2) · Bezmialem Vakif University (2) · European Society of Anaesthesiology (2) · Ospedale San Raffaele (2) · Wuerzburg University Hospital (2) · Azienda Ospedaliera di Padova (1) · Beth Israel Deaconess Medical Center (1) · Central Hospital, Nancy, France (1) · Hospital Nossa Senhora da Conceicao (1) · Hvivo (1) · Icagen (1) · Inmunotek S.L. (1) · Larissa University Hospital (1)
United States (16) · Italy (6) · Germany (4) · Brazil (3) · Spain (3) · Turkey (Türkiye) (3) · United Kingdom (3) · Belgium (2) · France (2) · Russia (2) · Albania (1) · Argentina (1) · Bosnia and Herzegovina (1) · Canada (1) · China (1)
Elena Bignami, MD (2) · Alexandre Lima, MD-PhD (1) · Allen T Funkhouser, MC (1) · Andreas Hoeft, MD (1) · Antonio Clavenna, MD (1) · Caterina B Bucca, MD (1) · Craig LaForce, MD (1) · David Miller, MD (1) · Emilie Jossen, BSc (1) · Francisco Javier Belda, MD (1) · Giuseppe Liistro, MD, PhD (1) · Harun Uysal, M.D. (1)
PMID 10573240, PMID 10892855, PMID 12620368, PMID 16055882, PMID 16226443, PMID 22743675, PMID 23067033, PMID 24534400, PMID 24901240, PMID 26020123, PMID 26036953, PMID 28592276, PMID 29865929, PMID 30224322, PMID 30431500, PMID 31351452, PMID 31607388, PMID 31613151, PMID 32387408, PMID 32423275, PMID 33705665, PMID 36870528, PMID 40551410, PMID 41729513, PMID 8499054
2009 (1)