53 completed, 12 unknown, 8 terminated, 7 recruiting. 36 Phase 2, 20 Not applicable, 10 Phase 4, 6 Phase 3, 5 Phase 1.
Follow Postherpetic Neuralgia: new trials by email Literature Review of Postherpetic Neuralgia trials Research Report on Postherpetic Neuralgia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Simultaneous Engagement of Networks for Alleviating Pain (SENAP) PFM-guided cortical stimulation - Neuropathic Pain, Postherpetic Neuralgia | Phase 1 | Not yet recruiting | University of Minnesota | 20 | 2026-11-01 | 2026-07-23 |
| Efficacy and Safety of High-Concentration 35 kDa Hyaluronan Gel for Herpes Zoster-Associated Pain 10% High-Concentration 35 kDa Hyaluronan (HA35) Topical Analgesic Gel - Herpes Zoster, Zoster-Associated Pain | Not applicable | Completed | Nakhia Impex LLC | 30 | 2026-05-01 | 2026-09-23 |
| Y-4 to Treat the Postherpetic Neuralgia Y-4 tables, Pregabalin - Postherpetic Neuralgia, Y-4 | Phase 2 | Recruiting | Neurodawn Pharmaceutical Co., Ltd. | 160 | 2026-02-02 | 2026-05-13 |
| Efficacy of Transcutaneous Pulsed Radiofrequency in Postherpetic Neuralgia Transcutaneous Pulsed Radiofrequency - Postherpetic Neuralgia, Chronic Pain | Recruiting | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization | 35 | 2026-02-01 | 2026-02-05 | |
| Brain Stimulation for Postherpetic Neuralgia: A Randomized Sham-Controlled Trial Non-invasive transcranial stimulation, Sham Non-invasive transcranial stimulation - Postherpetic Neuralgia | Not applicable | Not yet recruiting | Huazhong University of Science and Technology | 94 | 2026-01-20 | 2026-01-20 |
| The Analgesic Efficacy and Safety of Venlafaxine for Prevention of Postherpetic Neuralgia in Patients With Acute Herpes Zoster Venlafaxine combined conventional therapy, Conventional therapy - Herpes Zoster, Pain | Not applicable | Recruiting | Beijing Tiantan Hospital | 832 | 2025-12-15 | 2026-09-02 |
| Erector Spinae Plane Block Versus Transcutaneous Radiofrequency in Postherpetic Neuralgia Erector Spinae Plane Block - Postherpetic Neuralgia, Neuropathic Pain | Recruiting | Diskapi Teaching and Research Hospital | 50 | 2025-06-01 | 2026-02-25 | |
| The Effectiveness of Ultra-Sound Guided Erector Spinae Block With Betamethasone for Management of Truncal Chronic Post Herpetic Neuralgia. Medical management regimen, Erector spinae plane (ESP) block - Postherpetic Neuralgia, Chronic Pain | Not applicable | Recruiting | Cairo University | 40 | 2025-05-01 | 2025-06-05 |
| Esketamine Combined Pregabalin and Duloxetine for Postherpetic Neuralgia esketamine group, control group - Postherpetic Neuralgia | Not applicable | Recruiting | Beijing Tiantan Hospital | 150 | 2025-04-01 | 2025-04-27 |
| Esketamine Combined With PRF of DRG for Postherpetic Neuralgia esketamine+PRF treatment group, PRF treatment group - Postherpetic Neuralgia | Not applicable | Not yet recruiting | Beijing Tiantan Hospital | 186 | 2025-04-01 | 2025-04-09 |
| A Study of ONO-1110 in Patients With Postherpetic Neuralgia ONO-1110, Placebo - Postherpetic Neuralgia | Phase 2 | Completed | Ono Pharmaceutical Co., Ltd. | 142 | 2025-02-12 | 2026-07-15 |
| The Treatment of Postherpetic Neuralgia in the Head and Face With Superficial Needling Combined With Electroacupuncture electroacupuncture, Pregabalin - Postherpetic Neuralgia, Electroacupuncture | Not applicable | Unknown | Zhejiang Chinese Medical University | 124 | 2024-07-12 | 2025-04-06 |
| Relationship Between Serum Vitamin D Levels and Postherpetic Neuralgia. Postherpetic Neuralgia | Active not recruiting | Feng Gao | 144 | 2023-12-01 | 2024-01-30 | |
| Ultrasound-Guided Thoracic Paravertebral Block With Steroid and Local Anesthetic for Acute Herpes Zoster: Effects on Pain Control and Prevention of Postherpetic Neuralgia Valacyclovir + Paracetamol (Acetaminophen) + Gabapentin (standard medical therapy), Ultrasound-guided thoracic paravertebral block (TPVB) with bupivacaine 0.25% + methylprednisolone 40 mg - Postherpetic Neuralgia | Phase 3 | Completed | Assiut University | 100 | 2023-03-15 | 2026-01-20 |
| Clinical Trial of the Safety and Efficacy of Peripheral Nerve Stimulation in the Treatment of Peripheral Neuropathic Pain. Active electrostimulation, Placebo electrostimulation - Postherpetic Neuralgia, Peripheral Neuropathic Pain | Not applicable | Recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 60 | 2023-02-09 | 2025-07-28 |
| Correlation Between Thermal Patterns of Infrared Thermal Imaging and Clinical Phenotype in Patients With Postherpetic Neuralgia Postherpetic Neuralgia, Infrared Thermal Imaging | Unknown | Xianwei Zhang,MD | 166 | 2022-10-01 | 2022-10-05 | |
| Dorsal Root Ganglion Stimulation in Postherpetic Neuropathy Postherpetic Neuralgia | Completed | Istituti Clinici Scientifici Maugeri SpA | 77 | 2022-08-08 | 2026-03-19 | |
| Single-dose to Evaluate the Pharmacokinetics of GTX-101 and Subcutaneous Injectable Bupivacaine in Healthy Subjects GTX-101, Bupivacaine HCl subcutaneous injection - Postherpetic Neuralgia | Phase 1 | Unknown | Grace Therapeutics Inc. | 48 | 2022-07-26 | 2023-01-23 |
| To Evaluate the Efficacy and Safety of SR419 in Patients With Postherpetic Neuralgia (PHN) SR419 - Postherpetic Neuralgia | Phase 2 | Completed | Shanghai SIMR Biotechnology Co., Ltd. | 83 | 2022-05-13 | 2024-01-05 |
| Combined Application of Pulsed RF and Steroids to the DRG for PHN Epidural steroid, PRF plus steroids injection - Postherpetic Neuralgia, Chronic Pain | Not applicable | Completed | Mansoura University | 40 | 2022-02-01 | 2022-10-18 |
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Neuralgia, Postherpetic (86) · Herpes Zoster (22) · Neuralgia (17) · Pain (13) · Diabetic Neuropathies (7) · Chronic Pain (5) · Complex Regional Pain Syndromes (5) · Pain, Postoperative (4) · Peripheral Nerve Injuries (4) · Agnosia (3) · Peripheral Nervous System Diseases (3) · Chickenpox (2) · Polyneuropathies (2) · Trigeminal Neuralgia (2) · Acute Pain (1)
Nervous System Diseases (86) · Neurologic Manifestations (86) · Neuromuscular Diseases (86) · Pathological Conditions, Signs and Symptoms (86) · Signs and Symptoms (86) · Peripheral Nervous System Diseases (83) · Pain (73) · Neuralgia (69) · DNA Virus Infections (22) · Herpesviridae Infections (22) · Infections (22) · Varicella Zoster Virus Infection (22) · Virus Diseases (22) · Diabetes Complications (7) · Diabetes Mellitus (7)
Pregabalin (8) · Lidocaine (6) · Botulinum Toxins, Type A (3) · Gabapentin (3) · Valacyclovir (3) · 2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (2R)- (2) · Duloxetine Hydrochloride (2) · Etoricoxib (2) · Lidoderm (2) · Sodium Chloride (2) · 4-(3-chloro-5-(1,2-dihydroxyethyl)-2-pyridyl)-N-(5-(trifluoromethyl)-2-pyridyl)-3,6-dihydro-2H-pyridine-1-carboxamide (1) · Acetaminophen (1) · Acupuncture Therapy (1) · Administration, Cutaneous (1) · Amitriptyline (1)
Beijing Tiantan Hospital (4) · Pfizer (4) · Second Affiliated Hospital, Zhejiang University, School of Medicine (3) · Seoul National University (3) · Asan Medical Center (2) · Endo USA Inc., a Keenova Therapeutics Company (2) · Hospital Ambroise Paré Paris (2) · Janssen Pharmaceutical K.K. (2) · NeurogesX (2) · Ruhr University of Bochum (2) · UCB Pharma (2) · Winston Laboratories (2) · Aestus Therapeutics (1) · Albany Medical College (1) · Allergan (1)
United States (30) · China (18) · South Korea (7) · Germany (6) · Egypt (4) · Japan (4) · Australia (2) · Canada (2) · Denmark (2) · France (2) · South Africa (2) · Turkey (Türkiye) (2) · Austria (1) · Brazil (1) · Czechia (1)
Min Yan, Doctor (2) · Adelaide A. Hebert, MD (1) · Alexander Herman, MD (1) · Christoph Maier, Dr.med (1) · Christoph Maier, Prof.Dr.med (1) · Chunxia Lu (1) · David Darrow, MD (1) · David Lineberry (1) · Dexiong Han, M.D (1)
PMID 15930418, PMID 16466610, PMID 17258129, PMID 18164488, PMID 18419349, PMID 19469706, PMID 19475609, PMID 19712037, PMID 20439572, PMID 20863322, PMID 21356040, PMID 21422774, PMID 22151211, PMID 22182397, PMID 22828595, PMID 23633406, PMID 26359327, PMID 26947719, PMID 28158151, PMID 29189275, PMID 29381569, PMID 30954936, PMID 33298154, PMID 33400438, PMID 34095161, PMID 34254233, PMID 35257579, PMID 36729473, PMID 37024268, PMID 37366590, PMID 38015658, PMID 38050854, PMID 39320907, PMID 40950954, PMID 42189557, PMID 42765056
2009 (1), 2014 (1), R43AR052998 (1), R44NS059140 (1)