47 completed. 47 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 47 | Completed 47 |
Follow Phantom Limb: new trials by email Literature Review of Phantom Limb trials Research Report on Phantom Limb
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Botulinum Toxin Type A Versus Local Anesthetic Injection for Chronic Neuroma Pain After Combat-Related Amputation Botulinum Toxin Type A (BoNT-A), Local Anesthetic Solution - Chronic Pain Due to Injury, Neuroma of Lower Limb | Not applicable | Completed | Ukrainian Society of Regional Anesthesia and Pain Therapy | 100 | 2026-05-30 | 2026-10-27 |
| Proximal Nerve Cryoablation Versus Perineuroma Cryoablation for Chronic Neuroma Pain After Combat-Related Amputation Perineuroma Cryoablation, Proximal Nerve Cryoablation - Neuroma, Cryoablation | Not applicable | Completed | Ukrainian Society of Regional Anesthesia and Pain Therapy | 50 | 2026-05-23 | 2026-10-26 |
| Intrathecal Dexmedetomidine and Acute Neuropathic Pain After Lower Limb Amputation Hyperbaric Bupivacaine plus Saline, Hyperbaric Bupivacaine plus Dexmedetomidine - Phantom Limb Pain, Neuropathic Pain | Not applicable | Completed | Universidad Juárez Autónoma de Tabasco | 30 | 2025-09-30 | 2026-10-21 |
| Cryoanalgesia to Treat Phantom Limb Pain Following Above-Knee Amputation ACTIVE cryoneurolysis, SHAM cryoneurolysis - Amputation, Surgical, Amputation, Traumatic | Not applicable | Completed | University of California, San Diego | 12 | 2024-02-12 | 2026-04-08 |
| Sensory Retraining for Phantom Limb Pain Sensory retraining device - Phantom Limb Pain | Not applicable | Completed | Teesside University | 109 | 2024-02-09 | 2025-09-29 |
| Operant Conditioning of Sensory Brain Responses to Reduce Phantom Limb Pain in People With Limb Amputation Operant Conditioning with Peripheral Stimulation, Control Group with Peripheral Stimulation Only - Phantom Limb Pain After Amputation, Lower Limb Amputation | Not applicable | Completed | VA Office of Research and Development | 20 | 2023-07-01 | 2026-01-16 |
| Graded Motor Imagery in Phantom Limb Pain (GraMI Protocol) GraMI - Phantom Limb Pain | Not applicable | Completed | University of Vic - Central University of Catalonia | 36 | 2023-01-15 | 2024-01-31 |
| Effects of Prosthesis Training on Pain, Prosthesis Satisfaction and Ambulatory Status of Lower Limb Amputees Prosthesis Training, Phantom Exercises - Lower Limb Amputation Below Knee (Injury) | Not applicable | Completed | University of Lahore | 50 | 2023-01-01 | 2025-04-02 |
| The Effect of Distant Reiki on Pain and Holistic Well-being Distant reiki group - Phantom Limb Pain | Not applicable | Completed | Aksaray University Training and Research Hospital | 15 | 2022-10-20 | 2024-01-31 |
| Pulsed Electromagnetic Fields for Post-Amputation Pain Active then Sham Treatment, Sham then Active Treatment - Phantom Limb Pain, Residual Limb Pain | Not applicable | Completed | University of California, San Diego | 14 | 2022-08-05 | 2024-09-19 |
| The Pain in Amputees Reduced by Administration of Diet Examination Low-Carbohydrate Diet - Amputation, Phantom Limb Pain | Not applicable | Completed | University of Alabama at Birmingham | 28 | 2022-07-01 | 2023-08-30 |
| The Effects of Targeted Phantom Motor Execution on Phantom Limb Control Targeted phantom limb motor execution (exercise) - Phantom Limb, Motor Activity | Not applicable | Completed | University of Saskatchewan | 30 | 2022-06-01 | 2023-12-08 |
| Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain VR treatment for phantom limb pain - Phantom Limb Pain | Not applicable | Completed | Albert Einstein Healthcare Network | 46 | 2022-05-10 | 2026-09-30 |
| The Comparison of Sympathetic Blockade of Stellate Ganglion Block and Thoracic Paravertebral Block US-SGB, US-TPVB - Complex Regional Pain Syndromes, Postherpetic Neuralgia | Not applicable | Completed | Seoul National University | 69 | 2021-07-21 | 2023-10-17 |
| A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 2) BreEStim 120, BreEStim 240 - Pain Management | Not applicable | Completed | The University of Texas Health Science Center, Houston | 17 | 2021-04-02 | 2025-03-20 |
| A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 1) BreEStim, EStim - Pain Management | Not applicable | Completed | The University of Texas Health Science Center, Houston | 15 | 2021-04-02 | 2025-03-12 |
| A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 3) BreEStim 240, EStim 240 - Pain Management | Not applicable | Completed | The University of Texas Health Science Center, Houston | 18 | 2021-04-02 | 2025-03-20 |
| C-RFA of Residual Limb Neuroma Cooled Radiofrequency Ablation - Phantom Limb Pain, Neuroma Amputation | Not applicable | Completed | University of Utah | 8 | 2019-10-27 | 2025-01-08 |
| Mixed Reality Based System to Manage Phantom Pain Phantom Pain for Patients With Lower Limb Amputation Mr. MAPP - Phantom Limb Pain | Not applicable | Completed | Dallas VA Medical Center | 11 | 2018-05-21 | 2024-07-03 |
| Virtual Reality Treatment for Phantom Limb Pain Distractor and Lower limb VR - Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury) | Not applicable | Completed | University of Pennsylvania | 14 | 2018-01-12 | 2020-06-16 |
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Neuralgia (8) · Complex Regional Pain Syndromes (4) · Pain (4) · Agnosia (3) · Amputation, Traumatic (3) · Chronic Pain (3) · Neuroma (2) · Pain, Postoperative (2) · Spinal Cord Injuries (2) · Wounds and Injuries (2) · Acute Pain (1) · Causalgia (1) · Facial Pain (1) · Motor Activity (1)
Nervous System Diseases (47) · Neurobehavioral Manifestations (47) · Neurologic Manifestations (47) · Pathologic Processes (47) · Pathological Conditions, Signs and Symptoms (47) · Perceptual Disorders (47) · Postoperative Complications (47) · Signs and Symptoms (47) · Pain, Postoperative (45) · Pain (43) · Neuromuscular Diseases (10) · Peripheral Nervous System Diseases (10) · Wounds and Injuries (6) · Autonomic Nervous System Diseases (4) · Trauma, Nervous System (3)
Cryosurgery (2) · Acupuncture Therapy (1) · Botulinum Toxins, Type A (1) · Cognitive Behavioral Therapy (1) · Control Groups (1) · Cryotherapy (1) · Dexmedetomidine (1) · Diet, Carbohydrate-Restricted (1) · Drug Delivery Systems (1) · Exercise (1) · Gabapentin (1) · Mirror Movement Therapy (1) · Palliative Care (1) · Rehabilitation (1) · Sodium Chloride (1)
The University of Texas Health Science Center, Houston (3) · University of California, San Diego (3) · VA Office of Research and Development (3) · Integrum (2) · Ukrainian Society of Regional Anesthesia and Pain Therapy (2) · Aksaray University Training and Research Hospital (1) · Albert Einstein Healthcare Network (1) · Centre d'Investigation Clinique et Technologique 805 (1) · Clinical Centre of Serbia (1) · Dallas VA Medical Center (1) · Danish Pain Research Center (1) · Emory University (1) · Hunter Holmes Mcguire Veteran Affairs Medical Center (1) · Indiana University (1) · Lee Fisher, PhD (1)
United States (26) · Canada (3) · Sweden (3) · Denmark (2) · Ukraine (2) · United Kingdom (2) · Cambodia (1) · France (1) · Germany (1) · Ireland (1) · Italy (1) · Mexico (1) · Netherlands (1) · Pakistan (1) · Serbia (1)
Sheng Li, MD, PhD (3) · Brian Ilfeld, MD, MS (2) · An-Fu Hsiao, M.D., Ph.D. (1) · Ashfaq Ahmad, PhD (1) · Audrey Zucker-Levin, Professor (1) · Branch Coslett (1) · Brian Chau, MD (1) · Brian Ilfeld, M.D., M.S. (1) · Cormac Ryan, Professor (1) · Denise Lester, MD (1) · Dheeraj Gandhi (1) · Edward Chang, M.D. (1) · Fredrik Sebelius, PhD (1)
PMID 23740337, PMID 24616655, PMID 25873101, PMID 26324857, PMID 27782861, PMID 27916234, PMID 28051969, PMID 28830632, PMID 30012784, PMID 30954936, PMID 31501600, PMID 31740443, PMID 33417885, PMID 34761694, PMID 35152915, PMID 35461007, PMID 36006951, PMID 36273191, PMID 37276273, PMID 37332478, PMID 37947407, PMID 38378671, PMID 39250328, PMID 41033797, PMID 41213687, PMID 41255083
I21RX004410 (1), R01HD104158 (1), UH3NS100541 (1), UH3NS109556 (1)