16 completed, 4 unknown, 1 withdrawn. 15 Not applicable, 2 Phase 1, 2 Phase 3, 2 Phase 4, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 15 | Completed 11, Unknown 4 |
| Phase 1 | 2 | Completed 1, Withdrawn 1 |
| Phase 3 | 2 | Completed 2 |
| Phase 4 | 2 | Completed 2 |
| Phase 2 | 1 | Completed 1 |
Follow this drug Literature Review of Dental Devices, Home Care trials Research Report on Dental Devices, Home Care
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Powered Toothbrushing and Dental Flossing Sequence on Dental Plaque Removal Powered Toothbrushing, Dental Flossing - Dental Plaque | Not applicable | Completed | Lokman Hekim University | 46 | 2026-05-02 | 2026-07-30 |
| Comparative Efficacy of Floss and Essential Oil/CPC+Zn Mouthwashes in Reducing Dental Plaque and Gingivitis Mouthwash, Floss, Toothbrush - Dental Plaque, Gingivitis | Phase 4 | Completed | Colgate Palmolive | 228 | 2025-07-07 | 2025-10-30 |
| Comparative Study to Evaluate the Efficacy of an Alcohol-free Mouthwash Regimen With CPC+Zn, Flossing and Brushing, and an Alcohol-based Mouthwash Regimen With Essential Oils in Reducing Plaque and Gingivitis. Mouthwash CPC+Zn+F, Essential oils mouthwash, Dental floss - Gingival Bleeding, Plaque Induced Gingival Disease | Phase 3 | Completed | Colgate Palmolive | 120 | 2024-09-17 | 2025-04-14 |
| Comparative Study of CPC+Zn Mouthwash, Dental Floss, and Essential Oils Mouthwash on Plaque and Gingivitis Reduction Mouthwash CPC+Zn+F, Essential oils mouthrinse, Dental floss - Gingival Bleeding, Plaque Induced Gingival Disease | Phase 3 | Completed | Colgate Palmolive | 120 | 2024-09-16 | 2025-04-14 |
| Efficacy of Dental Hygiene Aids in Reducing Gingival Bleeding and Plaque Among Orthodontic Patients. water pik, Super floss - Gingival Bleeding, Dental Plaque | Not applicable | Completed | Ajman University | 102 | 2023-11-10 | 2024-08-15 |
| Effects of 0.2% Hyaluronic Acid Gel-Impregnated Dental Flosses on Clinical Gingival Parameters Dental floss+Gengigel, Dental Floss - Gingivitis | Not applicable | Completed | Özlem SARAÇ ATAGÜN | 30 | 2023-04-03 | 2024-03-12 |
| Assessment of Photodynamic Therapy With Annatto and Led for the Treatment of Halitosis in Mouth-Breathing Children Teeth Brushing, Dental Flossing, Tongue Scraping - Halitosis | Phase 1 / Phase 2 | Completed | University of Nove de Julho | 52 | 2023-02-01 | 2024-04-01 |
| Plaque Control Efficacy Between Interdental Brushes Versus Dental Floss Dental floss/Interdental brush - Periodontal Diseases, Dental Plaque | Not applicable | Completed | Fatima Jinnah Dental College | 90 | 2022-04-01 | 2022-06-30 |
| Effect of Local Cannabidiol on Clinical and Inflammatory Outcomes in Periodontal Maintenance Patients. cannabidiol, floss, proxabrush - Periodontitis, Adult, Inflammation Gum | Phase 1 | Withdrawn | University of Nebraska | 2020-05-14 | 2024-09-03 | |
| Oral Hygiene Tools for Biofilm Removal Around Implants • Dental Floss (Vitis®, Dentaid, Barcelona, Spain)., • Superfloss (Oral B®, Procter & Gamble, USA), • Oral irrigator (Waterpick®, Water Pik, Inc., CO., USA) - Healthy, Hygiene | Not applicable | Completed | Universitat Internacional de Catalunya | 120 | 2019-04-11 | 2024-11-20 |
| University of New Mexico Dental Hygiene Floss - Oral Plaque Biofilm | Not applicable | Completed | University of New Mexico | 72 | 2019-01-07 | 2019-03-15 |
| Effectiveness of the Use of Dental Floss Instructions oral hygiene with toothbrush plus dental floss, Instructions oral hygiene with toothbrush only - Gingivitis | Not applicable | Completed | Universidade Federal de Santa Maria | 76 | 2018-06-04 | 2022-05-18 |
| Halitosis During Active Orthodontic Treatment Manual Toothbrush, Dental floss, Waterjet - Halitosis | Not applicable | Unknown | Riyadh Colleges of Dentistry and Pharmacy | 60 | 2018-01-13 | 2019-04-03 |
| Effect of Dental Waterjet on Oral Hygiene for Patients With Braces Dental Water Jet, Dental Floss - Oral Hygiene | Not applicable | Unknown | Riyadh Colleges of Dentistry and Pharmacy | 30 | 2017-12-13 | 2018-12-31 |
| Curved Soft-Picks on Plaque Accumulation on Patients With Gingivitis Soft-Picks Advanced, Floss - Gingivitis | Not applicable | Completed | Sunstar Americas | 50 | 2016-12-01 | 2018-12-11 |
| Efficacy and Safety Study of Interproximal Cleaning Modalities on Oral Health AirFloss + BreathRx, AirFloss + Listerine, Dental Floss - Gingivitis | Not applicable | Completed | Philips Oral Healthcare | 290 | 2014-06-01 | 2016-03-08 |
| a Randomized Clinical Trial Evaluating Plaque Removal Around Dental Implants dental interproximal brush, dental floss - Peri Implantitis | Not applicable | Unknown | University of Manitoba | 32 | 2014-05-01 | 2016-04-06 |
| Oral Hygiene and Maternity Outcomes Multicenter Study (OHMOM) 0.243% sodium fluoride, toothbrush, dental floss - Gingivitis, Pregnancy | Not applicable | Completed | Procter and Gamble | 746 | 2012-02-01 | 2023-04-21 |
| Treatment of Initial Caries Lesions on Proximal Surfaces of Primary and Permanent Posterior Teeth Resin Infiltration, 30% Silver Diammine Fluoride, Dental Flossing - Dental Caries, Compliance Behavior | Not applicable | Unknown | University of Sao Paulo | 183 | 2012-01-01 | 2016-05-04 |
| A Controlled Clinical Study to Determine the Gingivitis Benefit of Flossing Experimental Floss - Gingivitis | Phase 4 | Completed | Procter and Gamble | 60 | 2009-01-01 | 2013-02-08 |
Showing 20 of 21. Sign in to see all of them.
Gingivitis (11) · Dental Plaque (7) · Periodontal Diseases (4) · Gingival Hemorrhage (3) · Halitosis (2) · Chronic Periodontitis (1) · Dental Caries (1) · Gingival Diseases (1) · Patient Compliance (1) · Peri-Implantitis (1) · Plaque, Amyloid (1)
Colgate Palmolive (3) · Procter and Gamble (2) · Riyadh Colleges of Dentistry and Pharmacy (2) · Ajman University (1) · Fatima Jinnah Dental College (1) · Lokman Hekim University (1) · Philips Oral Healthcare (1) · Sunstar Americas (1) · Universidade Federal de Santa Maria (1) · Universitat Internacional de Catalunya (1) · University of Lisbon (1) · University of Manitoba (1) · University of Nebraska (1) · University of New Mexico (1) · University of Nove de Julho (1)
United States (6) · Brazil (4) · Saudi Arabia (2) · Turkey (Türkiye) (2) · Canada (1) · Guatemala (1) · Mexico (1) · Pakistan (1) · Portugal (1) · Spain (1) · United Arab Emirates (1)
Aaron Biesbrock, DMD, PhD (1) · Andres Pascual La Rocca, PhD (1) · Antonio Moretti, DDS, MS (1) · Cassiano K Rosing, PhD (1) · Jeffery Milleman, DDS, MPA (1) · Joseph B Bavitz, DMD (1) · Mariana M Braga, PhD (1) · Mario F Bernardo, PhD (1) · Marjorie Jeffcoat, DMD (1) · Michael Reddy, DMD, DMSc (1) · Omar AlKadhi, BDS, MS (1) · Pejmon Amini, DDS (1)
PMID 25409545, PMID 26261052, PMID 35451656, PMID 37058047, PMID 37127210, PMID 38750375, PMID 39473003