10 completed, 6 unknown, 2 not yet recruiting, 2 recruiting. 20 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 20 | Completed 10, Unknown 6, Not yet recruiting 2, Recruiting 2 |
Follow Pain, Procedural: new trials by email Literature Review of Pain, Procedural trials Research Report on Pain, Procedural
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pain Control During Hysterosalpingography: A Three-Arm Randomized Trial Indomethacin 100Mg Suppository, Lidocaine %2 ampoule - Hysterosalpingography-Related Pain | Phase 4 | Not yet recruiting | Balikesir University | 180 | 2026-11-01 | 2026-10-15 |
| Topical Lidocaine for Digital Nerve Block Pain Topical Lidocaine Spray, Placebo Spray - Finger Injuries, Procedural Pain | Phase 4 | Completed | Ankara City Hospital Bilkent | 240 | 2026-04-01 | 2026-09-22 |
| To Explore the Optimal Dose of Dexmedetomidine for Skull Pin Fixation in Intracranial Surgery Dexmedetomidine - Procedural Pain | Phase 4 | Not yet recruiting | Kaohsiung Medical University Chung-Ho Memorial Hospital | 40 | 2025-03-01 | 2025-02-20 |
| Comparison of Compounded Topical Anesthetics Lidocaine topical, BLT - Procedural Pain | Phase 4 | Completed | Dartmouth-Hitchcock Medical Center | 63 | 2024-10-22 | 2026-05-05 |
| To Explore the Optimal Dose of Alfentanil for Skull Pin Fixation in Intracranial Surgery Alfentanil - Procedural Pain | Phase 4 | Unknown | Kaohsiung Medical University Chung-Ho Memorial Hospital | 40 | 2024-08-13 | 2024-08-20 |
| SPI and Remifentanil in Skull Pin Fixation Remifentanil - Pain, Procedural | Phase 4 | Unknown | Kaohsiung Medical University Chung-Ho Memorial Hospital | 27 | 2024-04-01 | 2024-03-26 |
| Self-Adjusted Nitrous Oxide: A Feasibility Study in the Setting of Vasectomy Nitrous oxide - Procedural Pain, Pain Catastrophizing | Phase 4 | Recruiting | Beth Israel Deaconess Medical Center | 35 | 2023-05-24 | 2026-02-06 |
| ANI and Remifentanil in Skull Pin Fixation. Remifentanil - Pain, Procedural | Phase 4 | Completed | Kaohsiung Medical University Chung-Ho Memorial Hospital | 27 | 2023-04-19 | 2024-03-21 |
| Regional Anesthesia Following Pediatric Cardiac Surgery Regional Anesthesia, Wound infiltration, Ropivacaine 0.2% Injectable Solution - Atrial Septal Defect, Ventricular Septal Defect | Phase 4 | Completed | Duke University | 52 | 2023-03-29 | 2025-08-28 |
| Lignocaine Only Versus Lignocaine Plus Magnesium Sulphate for Pain Relief After Episiotomy. Magnesium sulfate - Episiotomy Wound, Pain, Procedural | Phase 4 | Unknown | Rawalpindi Medical College | 62 | 2022-09-01 | 2022-06-14 |
| Ketamine as a Supplement to Local Anesthesia for Minor Procedures Ketamine, Saline - Pain, Procedural, Minor Laceration | Phase 4 | Recruiting | Loyola University | 108 | 2022-05-25 | 2025-10-03 |
| Clonidine as Pain Relief During ROP Eye Examinations Clonidine Oral Liquid Product, Sterile water - Retinopathy of Prematurity, Pain, Procedural | Phase 4 | Unknown | Region Örebro County | 50 | 2022-04-25 | 2022-05-04 |
| Ketamine Versus Fentanyl for Surgical Abortions Ketamine, Fentanyl - Abortion in First Trimester, Pain, Procedural | Phase 4 | Completed | University of Washington | 110 | 2021-04-27 | 2022-03-24 |
| Addition of Buprenorphine to Paracervical Block for Pain Control During Osmotic Dilator Insertion Buprenorphine 0.15 MG, Lidocaine 1% Injectable Solution - Procedural Pain, Buprenorphine | Phase 4 | Completed | University of California, San Diego | 57 | 2020-05-28 | 2023-08-01 |
| Alveogyl and Gelatin Sponge in the Management of Pain After Epithelialized Free Gingival Graft Harvesting Gelatin Sponge Sheet, Alvogyl - Pain, Procedural | Phase 4 | Unknown | Karim ehab gerges | 36 | 2019-04-01 | 2019-02-08 |
| Comparison of Two Application Techniques for LET Gel LET Lidocaine (4%), Epinephrine (0.1%), and Tetracaine (0.5%) topical gel - Lacerations, Pain, Procedural | Phase 4 | Completed | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | 48 | 2017-05-22 | 2021-02-18 |
| 40% Orally Administered Dextrose Gel is More Effective Than 25% Dextrose Dextrose - Acute Pain | Phase 4 | Completed | University of Targu Mures, Romania | 200 | 2014-09-01 | 2016-12-06 |
| Impact of 50% Nitrous Oxide Inhalation on Pain and Anxiety Induced by Lumbar Puncture: a Double-blind Randomized Controlled Trial 50:50 mixture of nitrous oxide/oxygen - Lumbar Puncture | Phase 4 | Unknown | University Hospital, Clermont-Ferrand | 66 | 2014-07-01 | 2015-09-21 |
| NeoFent-I Study; Fentanyl Treatment in Newborn Infants; a Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Study Fentanyl (5 microgram/ml) prediluted ampoules - Pain | Phase 4 | Completed | Lund University | 32 | 2012-11-01 | 2019-04-01 |
| Skin Blood Flow Changes Using Laser Doppler Imager for Assessment of Pain and Analgesia in Newborn Infants sucrose 24% oral solution, sterile water - Procedural Pain | Phase 4 | Completed | Children's Hospital of Michigan | 56 | 2005-09-01 | 2008-06-10 |
Pain (5) · Abscess (1) · Acute Pain (1) · Agnosia (1) · Dilatation, Pathologic (1) · Finger Injuries (1) · Heart Septal Defects, Atrial (1) · Heart Septal Defects, Ventricular (1) · Infertility (1) · Lacerations (1) · Retinopathy of Prematurity (1)
Neurologic Manifestations (20) · Pathological Conditions, Signs and Symptoms (20) · Signs and Symptoms (20) · Pain (15) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Wounds and Injuries (2) · Cardiovascular Abnormalities (1) · Cardiovascular Diseases (1) · Congenital Abnormalities (1) · Eye Diseases (1) · Genital Diseases (1) · Hand Injuries (1) · Heart Defects, Congenital (1) · Heart Diseases (1) · Heart Septal Defects (1)
Fentanyl (2) · Ketamine (2) · Lidocaine (2) · Remifentanil (2) · Alfentanil (1) · Anesthesia, Conduction (1) · Buprenorphine (1) · Dexmedetomidine (1) · Epinephrine (1) · Gels (1) · Glucose (1) · Indomethacin (1) · Linear Energy Transfer (1) · Magnesium Sulfate (1) · Nitrous Oxide (1)
Kaohsiung Medical University Chung-Ho Memorial Hospital (4) · Ankara City Hospital Bilkent (1) · Balikesir University (1) · Beth Israel Deaconess Medical Center (1) · Children's Hospital of Michigan (1) · Dartmouth-Hitchcock Medical Center (1) · Duke University (1) · Karim ehab gerges (1) · Loyola University (1) · Lund University (1) · Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (1) · Rawalpindi Medical College (1) · Region Örebro County (1) · University Hospital, Clermont-Ferrand (1) · University of California, San Diego (1)
United States (8) · Taiwan (3) · Sweden (2) · France (1) · Romania (1) · Turkey (Türkiye) (1)
Brian J Simmons, MD (1) · Hamna Atta, MBBS (1) · Heidi Rayala, MD, PhD (1) · Jennifer Chin, MD (1) · Josef Cortez, M.D. (1) · Kelly D Young, MD (1) · Lisa M Einhorn, MD (1) · Marissa Kent, MD (1) · Nicole Economou, MD (1) · Peter Steinberg, MD (1) · Sheila K Mody, MD, MPH (1) · Trent Reed, DO (1) · Victoria Tutag Lehr, Pharm.D. (1)
PMID 24918475, PMID 32144515, PMID 35100752, PMID 35926204, PMID 36137627, PMID 41032451
2014 (1)