25 terminated. 25 Phase 2, 2 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 25 | Terminated 25 |
| Phase 1 | 2 | Terminated 2 |
| Phase 3 | 2 | Terminated 2 |
Follow Pain, Postoperative: new trials by email Literature Review of Pain, Postoperative trials Research Report on Pain, Postoperative
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Duloxetine Impact on Postoperative Pain Control and Outcomes Duloxetine 60 MG, Placebo - Acute Post-operative Pain, Chronic Post Operative Pain | Phase 2 | Terminated | Scripps Health | 17 | 2023-05-30 | 2025-05-04 |
| A Trial of SHR0410 Injection in Postsurgical Pain Management SHR0410 Injection, Placebo for SHR0410 Injection - Postsurgical Pain | Phase 2 | Terminated | Jiangsu HengRui Medicine Co., Ltd. | 31 | 2022-08-09 | 2025-06-22 |
| Evaluation of the Dexmedetomidine Transdermal Systems for Postoperative Analgesia Following Abdominoplasty DMTS Patch, Placebo Patch - Pain, Postoperative | Phase 2 | Terminated | Teikoku Pharma USA, Inc. | 179 | 2022-07-07 | 2025-12-24 |
| Study Assessing Pain Relief After Replacement of the Knee ATX-101, bupivacaine hydrochloride without epinephrine - Acute Postoperative Pain | Phase 2 | Terminated | Allay Therapeutics, Inc. | 112 | 2022-06-07 | 2025-08-14 |
| Non-Opioid Pain Medications After Intracapsular Adenotonsillectomy Oxycodone, Ibuprofen, Acetaminophen - Adenotonsillectomy, Post-operative Analgesia | Phase 1 / Phase 2 | Terminated | David Chi, MD | 73 | 2021-04-13 | 2024-08-30 |
| Dosing of Methadone for Spine Surgery Standard dosing of methadone, Aliquots of methadone titrated to apnea - Pain, Postoperative | Phase 2 | Terminated | University of Florida | 21 | 2019-03-19 | 2026-06-23 |
| Exparel Interscalene vs Indwelling Catheter Exparel, Indwelling Interscalene Catheter - Pain | Phase 2 | Terminated | Montefiore Medical Center | 23 | 2019-01-22 | 2023-03-07 |
| Non-opioids for Analgesia After Adenotonsillectomy in Children Oxycodone, Ibuprofen, Acetaminophen - Adenotonsillectomy, Post-operative Analgesia | Phase 1 / Phase 2 | Terminated | David Chi, MD | 268 | 2018-10-25 | 2021-11-10 |
| Efficacy of Intrathecal Oxytocin to Speed Recovery After Hip Surgery Oxytocin, Placebo - Postoperative Pain | Phase 2 | Terminated | Wake Forest University Health Sciences | 126 | 2017-01-12 | 2022-11-23 |
| Dose Escalation of Dexamethasone to Increase Duration of Transversus Abdominal Plane Block Following Cesarean Section 2mg Dexamethasone, 4mg Dexamethasone, Ropivacaine (TAP blocks) - Post Surgical Pain | Phase 2 / Phase 3 | Terminated | University of Alabama at Birmingham | 29 | 2016-07-01 | 2021-06-18 |
| Genetic Predictors of Analgesic Efficacy of Propranolol for Treating Postoperative Pain Propranolol PO, IV-PCA morphine, Placebo PO - Postoperative Pain | Phase 2 | Terminated | McGill University Health Centre/Research Institute of the McGill University Health Centre | 10 | 2015-05-18 | 2021-09-28 |
| Effect of Bupivacaine-infused Fibrin Sealant Application on Post-tonsillectomy Pain & Hemorrhage Bupivacaine, Fibrin Sealant - Pain, Postoperative, Postoperative Hemorrhage | Phase 2 | Terminated | Indiana University | 18 | 2015-03-01 | 2018-08-10 |
| Use of Tapentadol Oral Solution for Pain After Surgery in Children From Newborn to Less Than 2 Years Old Tapentadol - Moderate to Severe Acute Postoperative Pain | Phase 2 | Terminated | Grünenthal GmbH | 40 | 2014-11-05 | 2018-01-29 |
| Placebo-Controlled Evaluation of Intranasal Dexmedetomidine for Postoperative Analgesia Following Bunionectomy Intranasal Dexmedetomidine, Intranasal Placebo - Pain, Post-operative | Phase 2 | Terminated | Baudax Bio | 95 | 2014-06-01 | 2015-12-10 |
| A Prospective Trial to Reduce Post-Operative Pain in Implant Based Breast Reconstruction Bupivacaine, Botulinum Toxins, Analgesics - Post-operative Pain | Phase 2 | Terminated | Yale University | 2 | 2014-04-01 | 2017-04-10 |
| An Analgesic Study to of V117957 for the Treatment of Postsurgical Pain Due to Third Molar Extraction V117957, Ibuprofen, Placebo - Postsurgical Pain Due to Third Molar Extraction | Phase 2 | Terminated | Purdue Pharma LP | 114 | 2013-07-01 | 2013-12-05 |
| Ultrasound-guided PVB ultrasoundguided paravertebral catheter - Thoracotomy Surgery, Anesthesia | Phase 2 | Terminated | Centre Jean Perrin | 60 | 2013-04-01 | 2014-03-20 |
| Lidocaine 5% Medicated Plaster in Chronic Neuropathic Postoperative Pain Lidocaine 5% medicated plaster, Placebo topical plaster - Pain, Chronic Pain | Phase 2 | Terminated | Grünenthal GmbH | 74 | 2010-08-01 | 2019-10-16 |
| Dose Finding Posterolateral Thoracotomy Study Low Dose SKY0402, High Dose SKY0402, Placebo - Postoperative Pain | Phase 2 | Terminated | Pacira Pharmaceuticals, Inc | 3 | 2008-12-01 | 2012-05-15 |
| Post-Operative Pain Scores and Analgesic Requirements After Elective Inguinal Herniorrhaphy Gabapentin, placebo - Pain, Analgesia | Phase 2 / Phase 3 | Terminated | University of Oklahoma | 5 | 2008-11-06 | 2017-04-28 |
Showing 20 of 25. Sign in to see all of them.
Pain (9) · Agnosia (4) · Chronic Pain (2) · Acute Pain (1) · Breast Neoplasms (1) · Bunion (1) · Hemorrhage (1) · Hernia, Inguinal (1) · Neuralgia (1) · Opioid-Related Disorders (1) · Osteoarthritis (1) · Osteoarthritis, Hip (1) · Postoperative Hemorrhage (1)
Neurologic Manifestations (25) · Pathologic Processes (25) · Pathological Conditions, Signs and Symptoms (25) · Postoperative Complications (25) · Signs and Symptoms (25) · Pain (16) · Nervous System Diseases (5) · Neurobehavioral Manifestations (4) · Perceptual Disorders (4) · Musculoskeletal Diseases (2) · Arthritis (1) · Breast Diseases (1) · Chemically-Induced Disorders (1) · Foot Deformities (1) · Foot Deformities, Acquired (1)
Bupivacaine (4) · Ibuprofen (3) · Acetaminophen (2) · Morphine (2) · Oxycodone (2) · Analgesia, Patient-Controlled (1) · Analgesics (1) · Botulinum Toxins (1) · Botulinum Toxins, Type A (1) · Buprenorphine (1) · Calcium Dobesilate (1) · Dexamethasone (1) · Diazepam (1) · Duloxetine Hydrochloride (1) · Epinephrine (1)
David Chi, MD (2) · Grünenthal GmbH (2) · Purdue Pharma LP (2) · Allay Therapeutics, Inc. (1) · Baudax Bio (1) · Centre Jean Perrin (1) · Indiana University (1) · Innocoll (1) · Jiangsu HengRui Medicine Co., Ltd. (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · Merck Sharp & Dohme LLC (1) · Montefiore Medical Center (1) · Pacira Pharmaceuticals, Inc (1) · Scripps Health (1) · Teikoku Pharma USA, Inc. (1)
United States (18) · Canada (2) · France (2) · United Kingdom (2) · Australia (1) · China (1) · Germany (1) · Poland (1)
David H Chi, MD (2) · Asokumar Buvanendran, MD (1) · Badie Mansour, MD (1) · Bruce H Matt, MD,MSc (1) · Christoph Seubert, MD (1) · David Prior (1) · Elilary Montilla Medrano, MD (1) · Gregory M Mundis, MD (1) · James C Eisenach, MD (1) · James C. Eisenach, MD (1) · James Song, MS, MA (1) · Jean Bruxelle (1) · Joel Feinstein, MD (1)
PMID 20052461, PMID 20418538, PMID 22337568, PMID 24535482, PMID 40396501
2009 (1), 2014 (1), R37GM048085 (1)