181 completed, 58 unknown, 27 recruiting, 21 not yet recruiting. 188 Not applicable, 19 Phase 3, 16 Phase 2, 10 Phase 4, 3 Phase 1.
Follow Foot Deformities, Acquired: new trials by email Literature Review of Foot Deformities, Acquired trials Research Report on Foot Deformities, Acquired
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 3 Bunionectomy Study CPL-01, saline placebo - Postoperative Pain, Bunion | Phase 3 | Not yet recruiting | Cali Pharmaceuticals LLC | 112 | 2027-03-01 | 2026-10-21 |
| Postsurgical Analgesia After Unilateral Bunionectomy AMT-143, Saline (NaCl 0,9 %) (placebo) - Bunionectomy, Bunion | Phase 2 | Not yet recruiting | AmacaThera Inc. | 60 | 2026-12-01 | 2026-10-22 |
| The Corrective Power of Subtalar Arthrodesis With Mini/Medial Bone Block (SAMBB) in Patients Affected by Progressive Collapsing Foot Deformity (PCFD): Analysis Using Weight-bearing Cone Beam CT. Weight-Bearing CT scan - Flat Foot | Not applicable | Not yet recruiting | Istituto Ortopedico Rizzoli | 20 | 2026-11-01 | 2026-10-09 |
| Correlation Between Soft Tissue Displacement and Functional Performance in Orthopedic Patients Nordic Hamstring Exercise Training, Custom Foot Orthoses and Exercise Therapy, Forearm Blood Flow Restriction Training - Hamstring Muscle Strain, Adult Acquired Flatfoot Deformity | Not applicable | Not yet recruiting | National Taiwan University Hospital | 80 | 2026-11-01 | 2026-10-21 |
| Effects of Custom 3D Printed Insoles and Short Foot Exercises in Pes Planus Custom 3D Printed Insoles and Short Foot Exercises - Pes Planus | Not applicable | Not yet recruiting | Kutahya Health Sciences University | 54 | 2026-10-26 | 2026-10-26 |
| Comparison Between Foot Segment Mulligan Mobilization and Ilium Mulligan Mobilization in Treatment Patellofemoral Pain Patients With Flatfeet: a Randomized Controlled Comparative Study mobilization with movement of the foot segment, Mobilization with movement of the Ilium, Hip-knee focused exercises - Patellofemoral Pain, PFP, Flatfeet | Not applicable | Not yet recruiting | Cairo University | 90 | 2026-10-01 | 2026-09-08 |
| Tibialis Posterior Muscle Morphology in Flexible Flatfeet Subjects Tibialis Posterior Muscle Morphology Assessment - Flexible Flatfoot | Not yet recruiting | Cairo University | 45 | 2026-10-01 | 2026-10-02 | |
| Comparing Effects of Custom Foot Orthotic Intervention to Foot-Core Training Protocol on Lower Extremity Kinematics in Runners With Pes Planus Custom foot orthoses, Intrinsic foot muscle strengthening exercises - Pes Planus, Running Related Injuries | Not applicable | Not yet recruiting | Dalhousie University | 24 | 2026-09-01 | 2026-07-23 |
| Acute Effects of Foot Orthoses on Muscle Mechanical Properties in Individuals With Pes Planus Insole, Medial Arch Support - Flatfoot | Not applicable | Not yet recruiting | Medipol University | 90 | 2026-09-01 | 2026-08-10 |
| Plantar Stimulation, Whole-Body Vibration, and Baduanjin for Muscle Activation Whole-body Vibration Training,Whole-Body Vibration With Regional Plantar Stimulation,Baduanjin - Flat Feet, Lower-Limb Muscle Activation | Not applicable | Recruiting | Nanfang Hospital, Southern Medical University | 30 | 2026-09-01 | 2026-09-10 |
| Immediate Effects of Plantar Fascia Release Combined With Foot Exercises on FMS Subscores in Young Adults With Pes Planus Protocol B: Foot Core Exercises, Plantar Fascia Stretching, and Myofascial Release, Protocol A: Foot core Exercises and Plantar Facia Streching - Pes Planus, FMS | Not applicable | Not yet recruiting | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | 29 | 2026-07-18 | 2026-06-29 |
| Effect of Foot Orthoses on Kneecap Position in Adults With Flexible Flatfoot Foot Orthoses - Patellofemoral Joint, Flatfoot | Not applicable | Not yet recruiting | Regionshospital Nordjylland | 10 | 2026-07-01 | 2026-07-28 |
| Return to Cross Country Skiing and Other Physical Activities After Arthrodesis of the First Metatarsophalangeal Joint Arthrodesis - Hallux Rigidus, Hallux Valgus | Not yet recruiting | Oslo University Hospital | 150 | 2026-06-01 | 2026-05-27 | |
| Investigation of the Relationship Between Pes Planus and Piriformis Syndrome: A Case-Control Study Piriformis Syndrome, Pes Planus | Active not recruiting | Kahramanmaras Sutcu Imam University | 70 | 2026-06-01 | 2026-06-29 | |
| Clinical Examination of Cavovarus Feet Clinical Examination - Cavus Foot | Recruiting | Royal National Orthopaedic Hospital NHS Trust | 30 | 2026-05-28 | 2026-06-12 | |
| Translation, Cross-cultural Adaptation, and Validation of the FPI-6 in Spain Spanish version of the Foot Posture Index (FPI-6) - Foot Deformities, Flatfoot | Not yet recruiting | Paloma López Ros | 100 | 2026-05-16 | 2026-05-15 | |
| Ultrasound Assessment of Achilles Tendon-Neurovascular Distance in Infants With Unilateral Clubfoot ultrasound - Clubfoot | Not yet recruiting | Assiut University | 40 | 2026-05-01 | 2026-03-16 | |
| Sensorimotor Technique on Navicular Drop in School Going Children sensorimotor technique, short foot exercise - Pes Planus | Not applicable | Completed | Riphah International University | 22 | 2026-04-14 | 2026-09-30 |
| Foot-Core Training With/Without Visual Feedback in Pediatric FPP Foot Core Training, Foot Core Training with Visual Feedback - Flexible Flatfoot | Not applicable | Completed | Riphah International University | 24 | 2026-04-13 | 2026-09-30 |
| Midfoot Osteotomy Versus 8-Plate Epiphysiodesis for Residual Metatarsal Adductus Midfoot Osteotomy, 8-Plate Epiphysiodesis - Club Foot | Not applicable | Not yet recruiting | Assiut University | 40 | 2026-03-30 | 2026-04-03 |
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Flatfoot (165) · Clubfoot (64) · Bunion (58) · Hallux Valgus (38) · Hallux Rigidus (29) · Pain, Postoperative (16) · Foot Deformities (13) · Pain (13) · Hallux Limitus (12) · Motor Activity (12) · Talipes Cavus (11) · Equinus Deformity (10) · Agnosia (7) · Ankylosis (7) · Acute Pain (6)
Musculoskeletal Diseases (327) · Foot Deformities (315) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (236) · Limb Deformities, Congenital (235) · Lower Extremity Deformities, Congenital (235) · Musculoskeletal Abnormalities (235) · Congenital Abnormalities (234) · Foot Deformities, Congenital (234) · Talipes (234) · Joint Diseases (57) · Pathological Conditions, Signs and Symptoms (56) · Signs and Symptoms (51) · Neurologic Manifestations (49) · Nervous System Diseases (27)
Foot Orthoses (12) · Bupivacaine (7) · Exercise (7) · Sodium Chloride (5) · Arthrodesis (4) · Exercise Therapy (4) · Gait Analysis (4) · Myofascial Release Therapy (4) · Botulinum Toxins, Type A (3) · Injections (3) · Muscle Stretching Exercises (3) · Oxycodone (3) · Restraint, Physical (3) · Ropivacaine (3) · Saline Solution (3)
Riphah International University (15) · Assiut University (9) · Cairo University (9) · Istituto Ortopedico Rizzoli (8) · Istanbul Medipol University Hospital (6) · University of British Columbia (6) · Hacettepe University (5) · National Taiwan University Hospital (5) · Pacira Pharmaceuticals, Inc (5) · Ankara Yildirim Beyazıt University (4) · Baudax Bio (4) · Heron Therapeutics (4) · Cali Pharmaceuticals LLC (3) · Chinese University of Hong Kong (3) · Istanbul University - Cerrahpasa (3)
United States (67) · Turkey (Türkiye) (58) · Pakistan (25) · Egypt (20) · Canada (15) · Italy (12) · Spain (11) · Taiwan (11) · France (9) · United Kingdom (7) · Denmark (6) · Hong Kong (5) · Sweden (5) · China (4) · Czechia (4)
Christine Alvarez, MD (3) · Rene Verdonk, MD, PhD (3) · Caterina Guerra, RN (2) · Christof Radler, MD (2) · Erol Onel (2) · Martin Gottliebsen, PhD-student (2) · Neil Singla, MD (2) · Pervez Ali, FCPS (2) · Samuel KK Ling, MBChB (2)
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