13 completed, 3 terminated, 2 withdrawn, 1 recruiting. 19 Phase 2, 2 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 19 | Completed 13, Terminated 3, Withdrawn 2, Recruiting 1 |
| Phase 1 | 2 | Completed 1, Terminated 1 |
| Phase 3 | 1 | Withdrawn 1 |
Follow Obsessive Compulsive Disorder: new trials by email Literature Review of Obsessive Compulsive Disorder trials Research Report on Obsessive Compulsive Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| SONATA LIFU for OCD Low Intensity Focused Ultrasound, Sham (No Treatment) - Obsessive Compulsive Disorder | Phase 2 | Recruiting | University of Pennsylvania | 40 | 2026-07-01 | 2026-07-27 |
| China Refractory Obsessive-Compulsive Disorder Deep Brain Stimulation Study Bilateral Nucleus Accumbens DBS (Suzhou Sceneray), Sham Bilateral Nucleus Accumbens DBS - Obsessive Compulsive Disorder | Phase 2 / Phase 3 | Withdrawn | Ruijin Hospital | 2015-04-01 | 2016-12-06 | |
| Intravenous Ketamine in the Treatment of Obsessive-Compulsive Disorder Ketamine, Midazolam - Obsessive Compulsive Disorder | Phase 1 / Phase 2 | Terminated | Wayne Goodman MD | 3 | 2012-06-01 | 2018-01-18 |
| Novel Medication Strategies Targeting Brain Mechanisms in Pediatric OCD Minocycline, Placebo - Obsessive Compulsive Disorder | Phase 2 | Completed | New York State Psychiatric Institute | 31 | 2012-05-01 | 2019-11-13 |
| Efficacy Study of Transcranial Magnetic Stimulation for Treatment of Obsessive-Compulsive Disorder Repetitive Transcranial Magnetic Stimulation (rTMS), Sham repetitive transcranial magnetic stimulation - Obsessive Compulsive Disorder | Phase 2 | Completed | University of Brasilia | 22 | 2011-05-01 | 2012-02-28 |
| Internet-based Cognitive Behavior Therapy (CBT) for Obsessive Compulsive Disorder (OCD) Internet-based cognitive behavior therapy, Support therapy on Internet - Obsessive Compulsive Disorder | Phase 2 | Completed | Karolinska Institutet | 101 | 2011-02-01 | 2018-03-21 |
| Exercise and Health Intervention for Patients With Obsessive Compulsive Disorder (OCD) Aerobic exercise, Health and Wellness - Obsessive Compulsive Disorder | Phase 2 | Completed | Butler Hospital | 56 | 2010-11-01 | 2015-07-22 |
| Efficacy of Agomelatine in Patients With Obsessive-Compulsive Disorder Agomelatine A, Placebo - Obsessive Compulsive Disorder | Phase 2 | Completed | Institut de Recherches Internationales Servier | 74 | 2010-05-01 | 2024-07-25 |
| Marinol in Trichotillomania or Obsessive Compulsive Disorder Dronabinol - Trichotillomania, Obsessive Compulsive Disorder | Phase 2 | Completed | University of Chicago | 14 | 2010-04-01 | 2023-02-23 |
| A Randomized, Double-Blind, Placebo-Controlled Trial of Flumazenil for the Treatment of Obsessive Compulsive Disorder Flumazenil - Obsessive Compulsive Disorder | Phase 2 | Terminated | Parkway Medical Center | 11 | 2009-10-01 | 2014-04-22 |
| Videophone Administered Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder Cognitive-behavioral therapy, Wait-list control - Obsessive Compulsive Disorder | Phase 2 | Completed | University of South Florida | 31 | 2009-03-01 | 2015-06-11 |
| Pilot Study of Minocycline (NPL-2003) in Adults With Obsessive-Compulsive Disorder (OCD) NPL-2003 - Obsessive Compulsive Disorder | Phase 2 | Completed | New York State Psychiatric Institute | 9 | 2008-08-01 | 2012-04-02 |
| Study of NPL-2003 in Adolescents With Obsessive Compulsive Disorder (OCD) Minocycline - Obsessive Compulsive Disorder | Phase 2 | Terminated | Neuropharm | 6 | 2007-07-01 | 2012-04-27 |
| N-methyl Glycine (Sarcosine) for the Treatment of Obsessive Compulsive Disorder (OCD) N-methyl glycine - Obsessive Compulsive Disorder | Phase 2 | Completed | China Medical University Hospital | 30 | 2007-06-01 | 2009-12-29 |
| Subthalamic Nucleus (STN) Stimulation and Obsessive-Compulsive Disorder (OCD) deep brain stimulation, No stimulation - Obsessive Compulsive Disorder | Phase 1 / Phase 2 | Completed | Marie-laure Welter | 16 | 2005-10-01 | 2018-03-22 |
| D-Cycloserine Augmentation of Exposure and Response Prevention Treatment for Obsessive-Compulsive Disorder D-Cycloserine - Obsessive Compulsive Disorder | Phase 2 | Withdrawn | University of Florida | 2005-07-01 | 2013-09-30 | |
| Addition of Quetiapine in Obsessive Compulsive Disorder - Westenberg Study Quetiapine - Obsessive Compulsive Disorder | Phase 2 | Completed | AstraZeneca | 90 | 2003-12-01 | 2011-01-21 |
| St. John's Wort Vs. Placebo in Obsessive-Compulsive Disorder. St. John's Wort - Obsessive Compulsive Disorder | Phase 2 | Completed | National Center for Complementary and Integrative Health (NCCIH) | 60 | 2002-05-01 | 2006-08-04 |
| Preventive Measures for Childhood-Onset Obsessive-Compulsive Disorder and Tic Disorders (PANDAS Subgroup) Penicillin or Placebo - Mental Disorder Diagnosed in Childhood, Obsessive Compulsive Disorder | Phase 2 | Completed | National Institute of Mental Health (NIMH) | 90 | 1993-04-01 | 2008-03-04 |
Obsessive-Compulsive Disorder (19) · Anxiety Disorders (1) · Compulsive Personality Disorder (1) · Excoriation Disorder (1) · Motor Activity (1) · Psychological Well-Being (1) · Streptococcal Infections (1) · Tic Disorders (1) · Trichotillomania (1)
Mental Disorders (19) · Anxiety Disorders (18) · Behavior (3) · Bacterial Infections (1) · Bacterial Infections and Mycoses (1) · Behavioral Symptoms (1) · Central Nervous System Diseases (1) · Disruptive, Impulse Control, and Conduct Disorders (1) · Gram-Positive Bacterial Infections (1) · Infections (1) · Movement Disorders (1) · Nervous System Diseases (1) · Neurodevelopmental Disorders (1) · Personal Satisfaction (1) · Personality Disorders (1)
Minocycline (2) · Cognitive Behavioral Therapy (1) · Cycloserine (1) · Deep Brain Stimulation (1) · Dronabinol (1) · Exercise (1) · Flumazenil (1) · Health (1) · Hypericum extract LI 160 (1) · Ketamine (1) · Midazolam (1) · Penicillins (1) · Quetiapine Fumarate (1) · Sarcosine (1) · Transcranial Magnetic Stimulation (1)
New York State Psychiatric Institute (2) · AstraZeneca (1) · Butler Hospital (1) · China Medical University Hospital (1) · Institut de Recherches Internationales Servier (1) · Karolinska Institutet (1) · Marie-laure Welter (1) · National Center for Complementary and Integrative Health (NCCIH) (1) · National Institute of Mental Health (NIMH) (1) · Neuropharm (1) · Parkway Medical Center (1) · Ruijin Hospital (1) · University of Brasilia (1) · University of Chicago (1) · University of Florida (1)
United States (11) · Brazil (1) · China (1) · France (1) · Israel (1) · Netherlands (1) · Sweden (1) · Taiwan (1)
Eric Storch, Ph.D. (2) · Ana M Abrantes, Ph.D. (1) · Bomin Sun, MD,PhD (1) · Carolyn I. Rodriguez, M.D., Ph.D. (1) · Guochuan E Tsai, MD, PhD (1) · James G Sullivan, MD (1) · Joaquim Brasil-Neto, MD, PhD (1) · Jon E Grant, JD, MD, MPH (1) · Joseph Zohar, Prof. (1) · Kenneth Kobak, PhD (1) · Kyle Lapidus, MD (1) · Leslie Taylo, MD (1) · Luc Mallet, MD, PhD (1)
PMID 19005196, PMID 20621362, PMID 20923629, PMID 20951978, PMID 21590520, PMID 22348650, PMID 37243560, PMID 37330252
2009 (1), R01MH086513 (1), R34MH095502 (1)