83 completed, 8 unknown, 7 terminated, 4 recruiting. 46 Not applicable, 19 Phase 2, 15 Phase 4, 5 Phase 3, 4 Phase 1.
Follow Obsessive Compulsive Disorder: new trials by email Literature Review of Obsessive Compulsive Disorder trials Research Report on Obsessive Compulsive Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| SONATA LIFU for OCD Low Intensity Focused Ultrasound, Sham (No Treatment) - Obsessive Compulsive Disorder | Phase 2 | Recruiting | University of Pennsylvania | 40 | 2026-07-01 | 2026-07-27 |
| Precision Analytic Research Methods in OCD Exposure and Response Prevention - Obsessive Compulsive Disorder | Not applicable | Recruiting | Icahn School of Medicine at Mount Sinai | 100 | 2025-07-09 | 2025-10-23 |
| Developing Brain, Impulsivity and Compulsivity Typical Development, Obsessive Compulsive Disorder | Recruiting | National Institute of Mental Health (NIMH) | 1100 | 2022-09-30 | 2026-09-25 | |
| Long-term Safety Study of Adjunctive Troriluzole in Subjects With Obsessive Compulsive Disorder Troriluzole (BHV-4157) - Obsessive Compulsive Disorder | Phase 3 | Terminated | Biohaven Pharmaceuticals, Inc. | 772 | 2021-03-30 | 2026-02-25 |
| ON/OFF Stimulation and Reward Motivation in Patients With Deep Brain Stimulators Deep Brain Stimulator - Obsessive Compulsive Disorder, Major Depressive Disorder | Not applicable | Completed | Massachusetts General Hospital | 13 | 2021-01-23 | 2026-04-28 |
| Neurostimulation and OCD, a MRI Study Sham rTMS, Active rTMS - Obsessive Compulsive Disorder | Not applicable | Completed | Hospital Center Guillaume Régnier | 30 | 2019-04-26 | 2025-10-06 |
| Combined Cortical/Subcortical Recording and Stimulation as a Circuit-Oriented Treatment for Obsessive-Compulsive Disorder Medtronic Percept Deep Brain Stimulation - Obsessive Compulsive Disorder | Not applicable | Active not recruiting | Massachusetts General Hospital | 2 | 2019-03-01 | 2025-12-19 |
| Neurobiology of Sensory Phenomena in Obsessive-Compulsive Disorder Tasked based functional MRI (fMRI), Eye Tracking Device - Obsessive Compulsive Disorder | Completed | NYU Langone Health | 308 | 2018-05-05 | 2024-07-26 | |
| Computerized Training for Individuals Diagnosed With Obsessive-Compulsive and Related Disorders Computerized Training - Obsessive Compulsive Disorder | Not applicable | Completed | Stanford University | 5 | 2018-04-30 | 2026-08-13 |
| Virtual Reality System to Increase Access to Exposure Therapy for Anxiety and OCD Virtual Reality - Anxiety, Obsessive Compulsive Disorder | Not applicable | Completed | Mayo Clinic | 40 | 2017-08-01 | 2018-11-13 |
| Integrating Pharmacogenomic Testing Into a Child Psychiatry Clinic Obsessive Compulsive Disorder, Major Depressive Disorder | Completed | University of Florida | 71 | 2016-09-01 | 2019-06-10 | |
| Inhibitory Control of the Mind : Neural Bases and Impact for Obsessive-compulsive Disorders Functional magnetic resonance imaging, behavioral measures, physiological measurements - Obsessive Compulsive Disorder, Healthy | Not applicable | Unknown | University Hospital, Caen | 48 | 2016-07-01 | 2016-08-01 |
| Tapering Off Antidepressants Two-Week Antidepressant Taper Regimen, One-Week Antidepressant Taper Regimen - Major Depressive Disorder, Anxiety Disorder | Not applicable | Terminated | Emory University | 2 | 2016-01-01 | 2018-09-25 |
| Deep Brain Stimulation of NAc/ALIC to Prevent Treatment-Refractory Obsessive Compulsive Disorder Deep brain stimulation, Fluoxetine - Obsessive Compulsive Disorder | Not applicable | Unknown | Tang-Du Hospital | 10 | 2015-11-01 | 2015-11-10 |
| Internet Delivered CBT for OCD in Adolescents With ASD - A Clinical Case Series Internet-delivered Cognitive Behavior Therapy - Obsessive Compulsive Disorder, Autism Spectrum Disorder | Not applicable | Completed | Karolinska Institutet | 4 | 2015-07-01 | 2016-09-07 |
| Transcranial Magnetic Stimulation (TMS) in Obsessive Compulsive Disorder (OCD): Mechanisms and Biomarkers Transcranial Magnetic Stimulation - Obsessive Compulsive Disorder | Not applicable | Completed | Massachusetts General Hospital | 26 | 2015-05-01 | 2026-02-13 |
| China Refractory Obsessive-Compulsive Disorder Deep Brain Stimulation Study Bilateral Nucleus Accumbens DBS (Suzhou Sceneray), Sham Bilateral Nucleus Accumbens DBS - Obsessive Compulsive Disorder | Phase 2 / Phase 3 | Withdrawn | Ruijin Hospital | 2015-04-01 | 2016-12-06 | |
| Fear Extinction and Mechanisms of Change in Obsessive Compulsive Disorder Behavior Therapy - Obsessive Compulsive Disorder | Not applicable | Completed | Massachusetts General Hospital | 54 | 2014-12-01 | 2022-03-31 |
| Sensory Gating Measured With Microelectrode Recording (MER) During Deep Brain Stimulation (DBS) Surgery Parkinson's Disease, Essential Tremor | Unknown | University of Colorado, Denver | 150 | 2014-12-01 | 2024-05-13 | |
| Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders Transdiagnostic Behavior Therapy, Behavioral Activation Therapy - Major Depressive Disorder, Persistent Depressive Disorder | Not applicable | Completed | VA Office of Research and Development | 105 | 2014-11-17 | 2019-08-28 |
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Obsessive-Compulsive Disorder (108) · Anxiety Disorders (13) · Tourette Syndrome (8) · Depressive Disorder, Major (6) · Mental Disorders (6) · Trichotillomania (5) · Dystonia (4) · Parkinson Disease (4) · Stress Disorders, Post-Traumatic (4) · Compulsive Behavior (3) · Compulsive Personality Disorder (3) · Depression (3) · Essential Tremor (3) · Generalized Anxiety Disorder (3) · Phobia, Social (3)
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PMID 19578654, PMID 20951978, PMID 19005196, PMID 19046587, PMID 19956460, PMID 19958042, PMID 20621362, PMID 20923629, PMID 21590520, PMID 21812991, PMID 21907540, PMID 22020357, PMID 22348650, PMID 22841131, PMID 23948637, PMID 24314349, PMID 24759852, PMID 25203167, PMID 25637377, PMID 26046412, PMID 27011177, PMID 28927961, PMID 29234089, PMID 29361268, PMID 29514116, PMID 29751168, PMID 30513489, PMID 31008633, PMID 31109199, PMID 31581800, PMID 31600432, PMID 31676206, PMID 31889307, PMID 31952071, PMID 32362128, PMID 32380442, PMID 32673037, PMID 33192400, PMID 34287023, PMID 34539777, PMID 34996343, PMID 35080598, PMID 35485920, PMID 36799958, PMID 36877480, PMID 37243560, PMID 37330252, PMID 39879875, PMID 41005270, PMID 41930538
2005 (2), R34MH095885 (2), 2009 (1), K23MH071754 (1), K23MH133997 (1), P30MH066386 (1), R01EB006136 (1), R01MH045436 (1), R01MH079217 (1), R01MH086513 (1), R01MH101163 (1), R21MH094537 (1), R21MH100444 (1), R21MH101441 (1), R34MH095502 (1)