12 completed, 3 terminated, 3 unknown, 2 recruiting. 4 Not applicable, 4 Phase 2, 3 Phase 3, 3 Phase 4, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 3, Unknown 1 |
| Phase 2 | 4 | Completed 2, Active not recruiting 1, Withdrawn 1 |
| Phase 3 | 3 | Terminated 2, Completed 1 |
| Phase 4 | 3 | Recruiting 2, Terminated 1 |
| Phase 1 | 1 | Completed 1 |
Follow Penicillins: new trials by email Literature Review of Penicillins trials Research Report on Penicillins
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comperasion the Postoperative Effect of Low Laser Therapy and Platelet Rich Fibrin on Mandibular Third Molar Surgery. Diagnoses, traditional osteotomies, platelet rich fibrin - Impacted Third Molar Tooth | Completed | Beste Erismen | 60 | 2024-01-02 | 2024-02-16 | |
| Evaluation of a Direct Oral Penicillin Challenge in a Rural Community Screening, Low dose Penicillin, Standard dose Penicillin - Allergy Penicillin | Not applicable | Unknown | Northern Ontario School of Medicine | 100 | 2023-10-06 | 2024-01-05 |
| Linezolid for Syphilis Pilot Study Group B, Linezolid 10d, Group A, Penicillin - Syphilis | Phase 2 | Active not recruiting | University of Southern California | 24 | 2023-09-28 | 2026-03-12 |
| Comparing Oral Versus Parenteral Antimicrobial Therapy Amoxicillin, amoxicillin-clavulanate, cefadroxil, cefpodoxime, cefalexin, ciprofloxacin, delafloxacin, doxycycline, levofloxacin, linezolid, Ampicillin, ampicillin-sulbactam, cefazolin, cefepime, ceftaroline, ceftazidime, ceftazidime-avibactam, dalbavancin, daptomycin, ertapenem - Endovascular Infection, Bone and Joint Infection | Phase 4 | Terminated | West Virginia University | 94 | 2023-08-04 | 2025-08-26 |
| NextGen - Clinical Implication of Next Generation Sequencing Antibiotic, Next Gen - Urinary Tract Infections | Phase 4 | Recruiting | Wake Forest University Health Sciences | 100 | 2022-05-17 | 2025-12-08 |
| Staphylococcus Aureus Network Adaptive Platform Trial Cefazolin, Penicillin, Clindamycin - Staphylococcus Aureus Bacteremia | Phase 4 | Recruiting | University of Melbourne | 8000 | 2022-02-16 | 2026-05-06 |
| Antibiotic Profile of Pathogenic Bacteria Isolated in Public Hospitals in Northern Jordan ciprofloxacin - Bacterial Infections, Antibiotic Resistant Infection | Completed | Yarmouk University | 24 | 2019-08-01 | 2021-11-04 | |
| Comparison The Postoperative Effects of Local and Systemic Antibiotics Applied With Platelets Rich Fibrin Diagnosis, traditional osteotomies, Platelet Rich Fibrin - Impacted Wisdom Tooth | Completed | Ceren Melahat Donmezer | 75 | 2019-03-17 | 2024-03-22 | |
| Beta-lactam Pharmacokinetics in Secondary Care Beta-lactam antibiotic - Pharmacokinetics, Beta Lactam Adverse Reaction | Completed | Imperial College London | 65 | 2017-07-12 | 2021-08-30 | |
| Population Pharmacokinetics of Anti-infective Drugs in Children With Infectious Diseases cephalosporins,penicillins,macrolides,carbapenems and antiviral drugs - Children; Infection | Unknown | Beijing Children's Hospital | 800 | 2017-06-21 | 2017-12-19 | |
| Innovative Treatments in Pneumonia (ITIP) 3 oral amoxicillin or parenteral ampicillin/ penicillin and gentamicin, parenteral ampicillin/ penicillin, gentamicin - Pneumonia | Completed | Save the Children | 1001 | 2016-10-19 | 2021-02-21 | |
| AllogeneiC Human Mesenchymal Stem Cells (hMSC) in Patients With Aging FRAilTy Via IntravenoUS Delivery Allogeneic Human Mesenchymal Stem Cells (allo-hMSCs), Placebo, Penicillin/Streptomycin-Free Allogeneic Human Mesenchymal Stem Cells (allo-hMSCs) - Frailty | Phase 1 / Phase 2 | Completed | Longeveron Inc. | 65 | 2014-03-03 | 2021-07-14 |
| Antibiotic Treatment and Intravenous Immunoglobulin Trial for PANDAS Sertraline+Antibiotic (penicillin/azithromycin), Sertraline+placebo, IVIG - Pandas | Phase 2 | Withdrawn | CNS Onlus | 2013-06-01 | 2023-02-21 | |
| Penicillin and Metronidazole in Treatment of Peritonsillar Abscess penicillin and metronidazole in peritonsillar abscess - Peritonsillar Abscess | Not applicable | Completed | Helsinki University Central Hospital | 200 | 2010-02-01 | 2021-05-11 |
| Simplified Antibiotic Regimens for Outpatient Treatment of Suspected Sepsis in Neonates and Young Infants in Bangladesh Gentamicin & Amoxicillin x 7days, Penicillin & gentamicin x 2 d + Amoxicillin X 5 d, Standard reference therapy - Sepsis | Not applicable | Completed | Johns Hopkins Bloomberg School of Public Health | 2490 | 2009-03-01 | 2014-09-16 |
| TELI TON - Telithromycin in Tonsillitis Telithromycin (HMR3647), Penicillin - Tonsillitis, Pharyngitis | Phase 3 | Terminated | Sanofi | 314 | 2006-03-01 | 2009-04-03 |
| TELI TAD - Telithromycin in Tonsillitis in Adolescents and Adults Telithromycin, Penicillin - Tonsillitis, Pharyngitis | Phase 3 | Terminated | Sanofi | 233 | 2006-02-01 | 2009-04-03 |
| Do Penicillin-allergic Patients Presents a High Risk of Sinus Lift Failure Penicillin - Maxillary Sinus Disease | Unknown | Universitat Internacional de Catalunya | 400 | 2004-07-01 | 2024-07-17 | |
| Study of Acupuncture and Care Interventions for the Treatment of Breast Inflammation During Breastfeeding Acupuncture treatment, Administration of oxytocin nasal spray, Improved breast milk removal - Mastitis | Not applicable | Completed | Karlstad University | 210 | 2002-01-01 | 2006-12-04 |
| Preventive Measures for Childhood-Onset Obsessive-Compulsive Disorder and Tic Disorders (PANDAS Subgroup) Penicillin or Placebo - Mental Disorder Diagnosed in Childhood, Obsessive Compulsive Disorder | Phase 2 | Completed | National Institute of Mental Health (NIMH) | 90 | 1993-04-01 | 2008-03-04 |
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Infections (3) · Pharyngitis (2) · Pneumonia (2) · Tonsillitis (2) · Anemia, Sickle Cell (1) · Bacterial Infections (1) · Breast Feeding (1) · Frailty (1) · Hematologic Diseases (1) · Hemoglobinopathies (1) · Mastitis (1) · Obsessive-Compulsive Disorder (1) · Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections (1) · Peritonsillar Abscess (1) · Recurrence (1)
Sanofi (2) · Beijing Children's Hospital (1) · Beste Erismen (1) · CNS Onlus (1) · Ceren Melahat Donmezer (1) · Helsinki University Central Hospital (1) · Imperial College London (1) · Institute of Child Health (1) · Johns Hopkins Bloomberg School of Public Health (1) · Karlstad University (1) · Longeveron Inc. (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · National Institute of Mental Health (NIMH) (1) · Northern Ontario School of Medicine (1) · Save the Children (1)
United States (8) · Argentina (2) · Canada (2) · Chile (2) · Costa Rica (2) · Cyprus (2) · Sweden (2) · United Kingdom (2) · Australia (1) · Bangladesh (1) · China (1) · Finland (1) · France (1) · Germany (1) · Israel (1)
A-Dong Shen, Master (1) · Abdullah H Baqui, MBBSMPHDrPH (1) · Alan Schwartz (1) · Alison H Holmes, MD MPH MBBS (1) · Amy Ginsburg, MD MPH (1) · Ann Bjornson (1) · Arif R. Sarwari, MD, MSc, MBA (1) · Beste Erismen Agan (1) · Bodil Wilde Larsson, PhD (1) · C. Holbrook (1) · Charles Pegelow (1) · David Becton (1) · Doris Wethers (1) · Elliott Vichinsky (1)
PMID 23254142, PMID 23945570, PMID 25155587, PMID 25628457, PMID 25841891, PMID 26289222, PMID 26755499, PMID 26968881, PMID 29507070, PMID 30962334, PMID 32075790, PMID 32129861, PMID 33020163, PMID 33627192, PMID 35012490, PMID 36403158, PMID 39934879, PMID 40134000, PMID 41419216, PMID 41433510, PMID 42308484, PMID 42309115