15 terminated. 15 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 15 | Terminated 15 |
Follow Nose Diseases: new trials by email Literature Review of Nose Diseases trials Research Report on Nose Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treatment of Acute Sinusitis With High-Dose vs. Standard-Dose Amoxicillin/Clavulanate Amoxicillin 875 mg, Placebo (lactase) - Sinusitis, Acute | Phase 4 | Terminated | Paul Sorum, MD | 157 | 2018-02-26 | 2021-08-12 |
| Effects of Intranasal Fluticasone Plus Azelastine on Airway Inflammation in Patients With Asthma & Allergic Rhinitis Azelastine-Fluticasone Nasal, Placebos - Asthma, Allergic, Rhinitis,Allergic | Phase 4 | Terminated | University of Dundee | 7 | 2017-01-20 | 2019-04-08 |
| Topical Intranasal Tranexamic Acid for Epistaxis in the Emergency Department Tranexamic Acid, 0.9% Sodium Chloride - Epistaxis | Phase 4 | Terminated | University of California, Davis | 35 | 2016-02-01 | 2021-11-30 |
| An Open-label Study to Identify Molecular Markers of Steroid Resistance mometasone furoate - Nasal Polyps | Phase 4 | Terminated | Massachusetts General Hospital | 11 | 2013-07-01 | 2018-06-12 |
| Corticosteroid Therapy for Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) Prednisone, Topical mometasone - Chronic Rhinosinusitis Without Nasal Polyps | Phase 4 | Terminated | Northwestern University | 9 | 2012-08-01 | 2018-03-30 |
| Compare the Effects of Fluticasone Furoate Nasal Spray vs Placebo in Patients With Nasal Polypoid Disease fluticasone furoate, placebo - Patients With Nasal Polyps | Phase 4 | Terminated | Johns Hopkins University | 7 | 2009-11-01 | 2017-09-13 |
| Interventional Cryotherapy for the Eradication of Benign Airway Disease ("ICE the BAD") CryoSpray Ablation - Lung Diseases, Obstructive, Sarcoidosis | Phase 4 | Terminated | CSA Medical, Inc. | 5 | 2008-10-01 | 2015-08-18 |
| Study of the Use of LUMA Lightwire Functional Endoscopic Sinus Surgery with Balloon Dilatation - Sinusitis | Phase 4 | Terminated | Lahey Clinic | 50 | 2008-03-01 | 2009-02-18 |
| Surgical Reduction of the Inferior Turbinates for Nasal Obstruction Surgical turbinate reduction procedure - Chronic Rhinitis, Inflammation of the Nasal Mucosa | Phase 4 | Terminated | ArthroCare Corporation | 30 | 2007-10-01 | 2015-08-26 |
| Study of Nasonex® in Improving Sleep Disturbances Related to Perennial Allergic Rhinitis (Study P04909)(TERMINATED) Mometasone Furoate Nasal Spray, Placebo - Perennial Allergic Rhinitis | Phase 4 | Terminated | Schering-Plough | 2006-09-01 | 2009-01-06 | |
| Treatment of Olfactory Dysfunction in Seasonal Allergic Rhinitis Mometasone, Placebo - Seasonal Allergic Rhinitis | Phase 4 | Terminated | University of Chicago | 17 | 2006-08-01 | 2014-02-28 |
| Study to Evaluate the Efficacy and Safety of Moxifloxacin Versus Amoxicillin/Clavulanate in the Treatment of Acute Bacterial Rhinosinusitis Moxifloxacin (Avelox, BAY12-8039), Amoxicillin/Clavulanate - Sinusitis, Bacterial Infections | Phase 4 | Terminated | Bayer | 293 | 2006-02-01 | 2014-11-07 |
| Study to Measure the Impact of Antibiotics on Bacterial Flora in Adults With Acute Sinusitis Azithromycin, Telithromycin - Maxillary Sinusitis | Phase 4 | Terminated | CPL Associates | 192 | 2005-12-01 | 2007-10-31 |
| The Addition of Montelukast to Fluticasone in the Treatment of Perennial Allergic Rhinitis Placebo, Montelukast, Fluticasone propionate - Rhinitis, Allergic, Perennial | Phase 4 | Terminated | University of Chicago | 102 | 2005-07-01 | 2014-02-28 |
| Seasonal Allergic Rhinitis and Driving Ability 1 week of treatment discontinuation - Seasonal Allergic Rhinitis | Phase 4 | Terminated | Utrecht Institute for Pharmaceutical Sciences | 22 | 2004-09-01 | 2008-04-15 |
Sinusitis (4) · Nasal Polyps (3) · Rhinitis, Allergic, Perennial (2) · Rhinitis, Allergic, Seasonal (2) · Asthma (1) · Bacterial Infections (1) · Epistaxis (1) · Focal Facial Dermal Dysplasias (1) · Granulomatosis with Polyangiitis (1) · Hypersensitivity (1) · Lung Diseases, Obstructive (1) · Maxillary Sinusitis (1) · Nasal Obstruction (1) · Paranasal Sinus Diseases (1) · Recurrent respiratory papillomatosis (1)
Otorhinolaryngologic Diseases (15) · Respiratory Tract Diseases (15) · Immune System Diseases (6) · Infections (6) · Respiratory Tract Infections (6) · Hypersensitivity (5) · Hypersensitivity, Immediate (5) · Respiratory Hypersensitivity (5) · Paranasal Sinus Diseases (4) · Pathological Conditions, Signs and Symptoms (4) · Rhinitis (4) · Rhinitis, Allergic (4) · Pathological Conditions, Anatomical (3) · Polyps (3)
Mometasone Furoate (4) · Amoxicillin (1) · Amoxicillin-Potassium Clavulanate Combination (1) · Azithromycin (1) · Cryoelectron Microscopy (1) · Cryosurgery (1) · Cryotherapy (1) · Fluticasone (1) · Glucocorticoids (1) · Lactase (1) · Moxifloxacin (1) · Prednisone (1) · Saline Solution (1) · Sodium Chloride (1) · Tranexamic Acid (1)
University of Chicago (2) · ArthroCare Corporation (1) · Bayer (1) · CPL Associates (1) · CSA Medical, Inc. (1) · Johns Hopkins University (1) · Lahey Clinic (1) · Massachusetts General Hospital (1) · Northwestern University (1) · Paul Sorum, MD (1) · Schering-Plough (1) · University of California, Davis (1) · University of Dundee (1) · Utrecht Institute for Pharmaceutical Sciences (1)
United States (10) · Italy (1) · Netherlands (1) · United Kingdom (1)
Aimee Moulin, MD (1) · Anthony M Magit, MD (1) · Brian Lipworth, MD (1) · Bruce Tan, MD (1) · Daniel Hamilos, MD (1) · Edmund Volkerts, PhD (1) · Jayant M Pinto, MD (1) · Jerome J Schentag, Pharm.D. (1) · Joris Verster, PhD (1) · Joseph Paladino, Pharm.D. (1) · Michael Machuzak, M.D. (1) · Paul C Sorum, MD, PhD (1) · Peter J Catalano, M.D. (1) · Robert M Naclerio, MD (1)
PMID 20674827, PMID 20819468, PMID 33755168
2005 (1), 2015 (1)