Respiratory Hypersensitivity: Clinical Trials

3910 completed, 607 unknown, 343 recruiting, 268 terminated. 1406 Not applicable, 892 Phase 3, 891 Phase 2, 594 Phase 4, 499 Phase 1.

By phase and status

Phase	Trials	Status
Not applicable	1406	Completed 901, Unknown 207, Recruiting 107, Not yet recruiting 63, Terminated 48, Withdrawn 41, Active not recruiting 27, Enrolling by invitation 8, Suspended 4
Phase 3	892	Completed 707, Unknown 49, Recruiting 40, Terminated 39, Withdrawn 32, Active not recruiting 12, Not yet recruiting 11, Enrolling by invitation 1, Suspended 1
Phase 2	891	Completed 664, Terminated 64, Withdrawn 45, Unknown 44, Recruiting 40, Active not recruiting 19, Not yet recruiting 13, Enrolling by invitation 2
Phase 4	594	Completed 433, Unknown 59, Terminated 42, Recruiting 17, Withdrawn 16, Active not recruiting 15, Not yet recruiting 10, Enrolling by invitation 2
Phase 1	499	Completed 395, Terminated 38, Unknown 23, Withdrawn 17, Recruiting 15, Active not recruiting 6, Not yet recruiting 5
Early Phase 1	33	Completed 20, Terminated 4, Unknown 4, Active not recruiting 3, Enrolling by invitation 1, Recruiting 1

Follow Respiratory Hypersensitivity: new trials by email Literature Review of Respiratory Hypersensitivity trials Research Report on Respiratory Hypersensitivity

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
EFFECT OF AYURVEDA TREATMENT IN ALLERGIC RHINITIS AYURVEDA treatment protocol, Control(Citrizine 10mg) - Allergic Rhinitis (AR)	Not applicable	Not yet recruiting	Amrita Vishwa Vidyapeetham	104	2028-06-30	2026-06-04
Effect of Linvemastat in Patients With Partially Controlled Asthma (syMMPonia) linvemastat, Placebo - Asthma (Diagnosis), Pulmonary Function	Phase 2	Not yet recruiting	Foresee Pharmaceuticals Co., Ltd.	135	2027-03-01	2026-07-20
Preventing Childhood Asthma Using Prophylactic House Dust Mite Allergen Immunotherapy HDM sublingual Immunotherapy, Placebo - Asthma, Allergy	Phase 2	Withdrawn	Boston Children's Hospital		2027-02-01	2024-11-26
Prevent Wheeze Trial Dexamethasone 0.6 mg/kilogram body weight single dose, Placebo - Lower Respiratory Tract Infection (LRTI), Recurrent Wheezing	Phase 4	Not yet recruiting	Norwegian University of Science and Technology	486	2027-02-01	2026-10-05
Educational Needs of Patients With Severe Asthma on Targeted Immunotherapies Initial assesment interwiew, Intake Interview with the Patient - Severe Asthma		Not yet recruiting	University Hospital, Angers	20	2027-01-04	2026-10-02
Efficacy and Safety of Slow Release Dehydroepiandrosterone (DHEA ) Slow Release DHEA, Placebo - Asthma	Phase 2	Not yet recruiting	Indiana University	30	2027-01-01	2026-02-27
Nebulized Ketamine for Severe Asthma Attacks in Children Ketamine (1 mg/kg), Placebo - Asthma Acute, Exacerbation of Allergic Asthma	Phase 2	Not yet recruiting	Sultan Qaboos University	60	2027-01-01	2026-07-27
Sustained Asthma Remission and Reduced Relapse Using a Comprehensive Management Strategy (SARRE-COMS) Comprehensive Biomarker-Guided Management Strategy, Standard of Care - Asthma (Diagnosis)	Not applicable	Not yet recruiting	Hana Serajeddini	50	2026-12-02	2026-09-25
Allergy, Asthma, and Atopic Eczema in Finland No intervention, No Intervention: Observational Cohort - Asthma, Asthma in Children		Not yet recruiting	Tampere University	1200000	2026-12-01	2026-10-15
Development and Validation of the Indian Asthma Care Bundle for Reducing Readmission and Improving Post-hospitalisation Care After Discharge From Hospital Due to an Acute Asthma Exacerbation Indian Asthma Care Bundle (I-ACB) - Asthma Exacerbation, Asthma (Diagnosis)	Not applicable	Not yet recruiting	Ahmedabad University	260	2026-12-01	2026-09-11
Tezepelumab (Tezspire) Regulatory Postmarketing Surveillance in Korea Severe Asthma, Chronic Rhinosinusitis With Nasal Polyps(CRSwNP)		Not yet recruiting	AstraZeneca	210	2026-11-28	2026-06-04
Safety and Efficacy Comparison Between CHF5993 100/6 12.5µg pMDI to Seretide Evohaler 125/25µg pMDI in Adolescent Subjects With Asthma CHF5993 100/6/12.5 μg pMDI HFA-152a, Seretide Evohaler - Asthma	Phase 3	Not yet recruiting	Chiesi Farmaceutici S.p.A.	700	2026-11-16	2026-10-05
Changing Lifestyle to Improve Quality of Life in Spanish Adolescents With Asthma Lifestyle-change intervention - Asthma (Diagnosis)	Not applicable	Not yet recruiting	Universitat Internacional de Catalunya	96	2026-11-02	2026-10-22
Post-market Clinical Follow-up Study of an Isotonic Saline Solution for the Relief of Nasal Congestion in Infants and Toddlers Quinton Medical Nasal Health Baby® - Nasal Congestion, Common Cold		Not yet recruiting	Laboratoires Quinton International S.L.	83	2026-11-01	2026-10-13
Validation of 1 Minute Sit-to Stand Test for Assessment of Breathlessness at Exertion in Individuals With Chronic Lung Disease 1MSTS - COPD (Chronic Obstructive Pulmonary Disease), Asthma (Diagnosis)		Not yet recruiting	Jacob Sandberg	120	2026-11-01	2026-09-23
Anakinra Rescue Treatment for Moderate Asthma Attacks (ARTMA) Anakinra 100 Mg/0.67 Ml Inj Syringe, Saline Placebo/0.67 Ml Inj Syringe - Asthma (Diagnosis), Persistent Asthma	Phase 1	Not yet recruiting	University of North Carolina, Chapel Hill	60	2026-11-01	2026-07-15
Novel Method for Removal of Orally Deposited Inhaled Fluticasone Propionate Fluticasone Propionate, Water Mouthwash, EVOOW Mouthwash - Asthma	Phase 4	Not yet recruiting	University of Wisconsin, Madison	20	2026-11-01	2026-09-24
Fatty Acids in Airway Smooth Muscle of Asthmatics coconut oil - Asthma	Not applicable	Withdrawn	Brigham and Women's Hospital		2026-11-01	2024-10-23
Ginger's Therapeutic Potential in Asthma Ginger Extract, Placebo - Asthma	Phase 2	Not yet recruiting	Emily DiMango, MD	32	2026-11-01	2026-08-28
Real-World Effectiveness of Depemokimab in Allergic Bronchopulmonary Aspergillosis With Severe Eosinophilic Asthma Depemokimab - Allergic Bronchopulmonary Aspergillosis, ABPA	Not applicable	Not yet recruiting	Qianfoshan Hospital	10	2026-11-01	2026-09-24

Showing 20 of 5596. Sign in to see all of them.

Narrower conditions

Asthma (4460)  ·  Rhinitis, Allergic (680)  ·  Pulmonary Disease, Chronic Obstructive (442)  ·  Rhinitis, Allergic, Seasonal (384)  ·  Hypersensitivity (269)  ·  Rhinitis, Allergic, Perennial (178)  ·  Lung Diseases (149)  ·  Rhinitis (106)  ·  Obesity (93)  ·  Disease (87)  ·  Inflammation (79)  ·  Respiratory Sounds (75)  ·  Dyspnea (68)  ·  Heart Failure (68)  ·  Diabetes Mellitus (67)

Broader conditions

Hypersensitivity, Immediate (5579)  ·  Immune System Diseases (5575)  ·  Respiratory Tract Diseases (5539)  ·  Hypersensitivity (5327)  ·  Bronchial Diseases (4510)  ·  Lung Diseases, Obstructive (4432)  ·  Lung Diseases (4403)  ·  Otorhinolaryngologic Diseases (1207)  ·  Nose Diseases (1186)  ·  Rhinitis (1053)  ·  Pathological Conditions, Signs and Symptoms (999)  ·  Pathologic Processes (692)  ·  Disease Attributes (509)  ·  Rhinitis, Allergic (455)

Interventions

Fluticasone (214)  ·  Budesonide (188)  ·  montelukast (172)  ·  Albuterol (159)  ·  Formoterol Fumarate (105)  ·  Mometasone Furoate (94)  ·  Beclomethasone (87)  ·  Fluticasone-Salmeterol Drug Combination (86)  ·  Salmeterol Xinafoate (80)  ·  Budesonide, Formoterol Fumarate Drug Combination (79)  ·  Omalizumab (78)  ·  fluticasone furoate (57)  ·  ciclesonide (54)  ·  benralizumab (49)  ·  mepolizumab (49)

Sponsors

AstraZeneca (336)  ·  GlaxoSmithKline (324)  ·  Organon and Co (127)  ·  Novartis Pharmaceuticals (81)  ·  National Heart, Lung, and Blood Institute (NHLBI) (76)  ·  Boehringer Ingelheim (66)  ·  Chiesi Farmaceutici S.p.A. (62)  ·  Teva Branded Pharmaceutical Products R&D, Inc. (55)  ·  Sanofi (50)  ·  Imperial College London (48)  ·  National Institute of Allergy and Infectious Diseases (NIAID) (42)  ·  Brigham and Women's Hospital (41)  ·  University of California, San Francisco (35)  ·  National Institute of Environmental Health Sciences (NIEHS) (34)  ·  Johns Hopkins University (33)

Countries

United States (1856)  ·  United Kingdom (565)  ·  Canada (485)  ·  Germany (460)  ·  China (327)  ·  France (324)  ·  Poland (278)  ·  Spain (242)  ·  Italy (195)  ·  Netherlands (172)  ·  Russia (165)  ·  South Korea (162)  ·  Argentina (154)  ·  Belgium (152)  ·  Brazil (149)

Top investigators

Louis-Philippe Boulet, MD (20)  ·  Elliot Israel, MD (15)  ·  Luo Zhang (13)

Results publications

PMID 36472162, PMID 27881132, PMID 39393433, PMID 31319851, PMID 29400693, PMID 32926419, PMID 35691614, PMID 33217063, PMID 38127464, PMID 19001265, PMID 26704701, PMID 30954640, PMID 18331513, PMID 22329608, PMID 24184147, PMID 28065396, PMID 29174062, PMID 29536781, PMID 29656145, PMID 32180164, PMID 33305842, PMID 34098955, PMID 35636689, PMID 10573240, PMID 14713908, PMID 20075384, PMID 20851928, PMID 21060320, PMID 21439168, PMID 22464647, PMID 23374268, PMID 24035151, PMID 24838406, PMID 24966061, PMID 26369589, PMID 26498386, PMID 26612545, PMID 28602936, PMID 29768147, PMID 29768149, PMID 30802500, PMID 30876830, PMID 31047111, PMID 31251094, PMID 31447130, PMID 31613151, PMID 31760132, PMID 31798645, PMID 32298853, PMID 33223095

NIH funding

2015 (31), 2016 (30), 2009 (25), 2014 (24), 2023 (22), 2018 (20), 2017 (19), 2019 (18), 2025 (16), 2008 (13), U10HL098115 (8), 2004 (6), U10HL074212 (6), 2005 (5), P01HL107202 (5)