169 completed, 44 unknown, 22 terminated, 18 withdrawn. 104 Not applicable, 39 Phase 4, 34 Phase 3, 27 Phase 2, 14 Phase 1.
Follow Sinusitis: new trials by email Literature Review of Sinusitis trials Research Report on Sinusitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Post-market Clinical Follow-up Study of an Isotonic Saline Solution for the Relief of Nasal Congestion in Infants and Toddlers Quinton Medical Nasal Health Baby® - Nasal Congestion, Common Cold | Not yet recruiting | Laboratoires Quinton International S.L. | 83 | 2026-11-01 | 2026-10-13 | |
| Observational Study of RHINOSEDAL in Acute Nasal Obstruction RHINOSEDAL - Nasal Obstruction, Common Cold | Not yet recruiting | Laboratoires Elerte | 126 | 2026-10-15 | 2026-06-02 | |
| Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI) Respiratory Tract Infection, Smell Disorder | Recruiting | National Institute on Deafness and Other Communication Disorders (NIDCD) | 80 | 2026-10-01 | 2026-10-09 | |
| Comparative Effectiveness of Available Treatments for Sinus and Ear Infections in Children (Acute Sinusitis) Amoxicillin, Amoxi Clavulanate, Amoxicillin Placebo - ACUTE SINUSITIS, Sinusitis | Phase 4 | Recruiting | Nader Shaikh | 1100 | 2026-10-01 | 2026-10-20 |
| Efficacy of Bee Venom Phonophoresis in Treating Chronic Sinusitis: Bee Venom Phonophoresis, Standard Care (oral decongestants + saline nasal irrigation) - Chronic Sinusitis, Acute Sinusitis | Not applicable | Not yet recruiting | Sinai University | 30 | 2026-08-15 | 2026-08-04 |
| Biologics in Chronic Rhinosinusitis With Nasal Polyposis Biologic Agents - Chronic Sinusitis, Nasal Polyps | Phase 4 | Recruiting | Medical University of South Carolina | 504 | 2026-06-03 | 2026-09-28 |
| A Phase 1 Study of Cizutamig in IgE Mediated Diseases Cizutamig - IgE-Mediated Hypersensitivity, IgE Mediated Food Allergy | Phase 1 | Withdrawn | Candid Therapeutics | 2026-04-01 | 2026-07-22 | |
| RhinAV_Evaluation of Treatments for Acute Viral Rhinitis, Rhinosinusitis, and Rhinopharyngitis PIR, NS, NHE - Rhinitis Acute, Rhinitis Viral | Not applicable | Recruiting | University Hospital, Clermont-Ferrand | 150 | 2026-02-25 | 2026-06-15 |
| Herbal Tea Extract for Management of Rhinosinusitis mango leaves extract, local steroids, nasal saline - Rhino Sinusitis | Not applicable | Completed | Deraya University | 30 | 2025-11-20 | 2026-04-16 |
| Deviated Nasal Septum Effect on Maxillary Sinus Volumes and Development of Maxillary Sinusitis by CT Deviated Nasal Septum and Maxillary Sinusitis | Not yet recruiting | Assiut University | 120 | 2025-10-01 | 2025-10-07 | |
| Endoscopic Assessment of Schneiderian Membrane Perforation During Osseodensification-mediated Transcrestal Sinus Floor Elevation With Graftless Immediate Implant Placement in Subsinus Bone Height of 4-6 mm: A Pilot Study. Scheiderian Membrane Perforation - Sinusitis, Periodontal Disease | Not applicable | Completed | Saint-Joseph University | 6 | 2025-09-01 | 2026-05-01 |
| Radiological and Surgical Analysis of Frontal Recess Variations in Endoscopic Sinus Surgery endosocpic sinus surgery - Frontal Sinusitis, Endoscopic Sinus Surgery | Not applicable | Completed | Al-Azhar University | 40 | 2025-09-01 | 2026-08-06 |
| The Efficacy and Safety of Raphamin in the Treatment of Acute Rhinosinusitis in Adult Patients Raphamin, Placebo - Rhinosinusitis, Rhinosinusitis Acute | Phase 3 | Recruiting | Materia Medica Holding | 552 | 2025-04-03 | 2026-03-16 |
| Efficacy of Two Nasal Products Based on Diluted Seawater in the Treatment of Upper Respiratory Infections/Conditions administration of an isotonic seawater solution (9g/L) in the nose, administration of a hypertonic seawater solution (21g/L) in the nose - Rhinitis, Sinusitis | Not applicable | Completed | YSLab | 89 | 2025-03-18 | 2026-08-19 |
| Reducing Antibiotic Use by Implementation of Stewardship in Primary and Urgent Care Online Educational Modules, Prescribing Feedback Reports, Clinical Decision Support - Community Acquired Pneumonia (CAP), Sinusitis | Active not recruiting | Children's Hospital of Philadelphia | 420 | 2025-02-18 | 2026-04-14 | |
| Endoscopic Direct "Draf IIa" (Carolyn's Window Approach) Versus Endoscopic Angled "Draf IIa"Approach in Chronic Rhinosinusitis With Frontal Sinus Affection ( A Comparative Study ). Endoscopic direct Draf IIa, Endoscopic angled Draf IIa - Chronic Rhinosinusitis (CRS), Frontal Sinusitis | Not applicable | Not yet recruiting | Assiut University | 68 | 2025-01-01 | 2024-10-31 |
| How OMT Benefits Newly Diagnosed Patients With Respiratory Illness When Given Alongside Other Standard Care. Lymphatic Pump Osteopathic Manipulative Therapy - Pneumonia, Sinusitis | Not applicable | Recruiting | Geisinger Clinic | 68 | 2024-12-31 | 2026-08-11 |
| A Study to Investigate Changes in Symptoms in Adult Participants With Chronic Rhinosinusitis With Nasal Polyposis Initiating Treatment With Tezepelumab Tezepelumab - Chronic Rhinosinusitis With Nasal Polyps | Phase 3 | Active not recruiting | AstraZeneca | 181 | 2024-12-03 | 2026-10-07 |
| A Study to Evaluate 611 in Patients With Chronic Rhinosinusitis With Nasal Polyps 611, Placebo - Sinusitis, Nasal Polyps | Phase 3 | Active not recruiting | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | 243 | 2024-11-22 | 2025-12-03 |
| Harnessing Digital Medicine to Improve Allergic Rhinitis Management in Primary Care (DMAR) QHSLab Digital Tools (AME and ARIS) - Allergic Rhinitis, Sinusitis | Not applicable | Enrolling by invitation | QHSLab, Inc. | 240 | 2024-11-18 | 2026-02-09 |
Showing 20 of 283. Sign in to see all of them.
Rhinosinusitis (90) · Nasal Polyps (29) · Respiratory Tract Infections (20) · Rhinitis (18) · Bronchiolitis Obliterans Syndrome (17) · Maxillary Sinusitis (15) · Rhinitis, Allergic (14) · Asthma (13) · Paranasal Sinus Diseases (10) · Disease (9) · Bronchitis (8) · Common Cold (8) · Allergic Fungal Sinusitis (7) · Cystic Fibrosis (7)
Infections (280) · Nose Diseases (279) · Otorhinolaryngologic Diseases (277) · Respiratory Tract Diseases (277) · Paranasal Sinus Diseases (273) · Respiratory Tract Infections (263) · Rhinitis (89) · Pathological Conditions, Signs and Symptoms (62) · Immune System Diseases (52) · Lung Diseases (43) · Lung Diseases, Obstructive (37) · Bronchial Diseases (36) · Hypersensitivity (34) · Respiratory Hypersensitivity (34)
Amoxicillin-Potassium Clavulanate Combination (13) · Sodium Chloride (11) · Budesonide (9) · Amoxicillin (7) · Azithromycin (7) · dupilumab (6) · Levofloxacin (5) · Pseudoephedrine (5) · Moxifloxacin (4) · Saline Solution (4) · telithromycin (4) · Acetaminophen (3) · Anti-Bacterial Agents (3) · Guaifenesin (3) · Mometasone Furoate (3)
St. Paul's Hospital, Canada (8) · Entellus Medical, Inc. (6) · Integra LifeSciences Corporation (6) · GlaxoSmithKline (5) · Sanofi (5) · Assiut University (4) · Bayer (4) · Cairo University (4) · Greg Davis (4) · Pfizer (4) · University of Jena (4) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (3) · Oregon Health and Science University (3) · University of Alabama at Birmingham (3) · University of North Carolina, Chapel Hill (3)
United States (120) · Canada (30) · Germany (17) · France (14) · China (11) · Egypt (10) · Spain (8) · Israel (7) · Poland (7) · Finland (6) · Italy (6) · Saudi Arabia (6) · Czechia (5) · Russia (5) · Argentina (4)
Amin Javer, MD (5) · Amin R Javer, MD, FRCSC, FARS (4) · Ellen R Wald, MD (4) · Greg E Davis, MD, MPH (4) · Arif Janjua, MD (2) · Benjamin S Bleier, MD (2) · Brad Woodworth, MD (2) · Jay F Piccirillo, MD (2) · Jeff Grebner (2) · Jerome J Schentag, Pharm.D. (2) · Jochen Mainz, M.D. (2)
PMID 25137523, PMID 10480701, PMID 12049564, PMID 12091997, PMID 15023840, PMID 15125017, PMID 15316237, PMID 15510034, PMID 17063747, PMID 17178300, PMID 17405780, PMID 17424883, PMID 17882910, PMID 18559163, PMID 19344620, PMID 19419611, PMID 19559969, PMID 19564277, PMID 19794023, PMID 20422704, PMID 20428282, PMID 20500134, PMID 20513050, PMID 21038023, PMID 21271600, PMID 21453656, PMID 21844413, PMID 21994147, PMID 22170775, PMID 22287332, PMID 22287426, PMID 22337680, PMID 22736422, PMID 22764607, PMID 22887970, PMID 23136057, PMID 23255493, PMID 23378777, PMID 23424023, PMID 23621514, PMID 23626752, PMID 23682979, PMID 23710844, PMID 23785241, PMID 24358625, PMID 24594542, PMID 24598043, PMID 24610673, PMID 24753507, PMID 24889751
2005 (1), 2019 (1), 2023 (1), K08HL107142 (1), M01RR000069 (1), R01AI097172 (1), R01HL116213 (1), R37HL068546 (1), U01AI064655 (1), U01AI118506 (1)