119 completed, 30 terminated, 6 unknown, 5 withdrawn. 59 Phase 2, 38 Phase 3, 26 Phase 1, 25 Phase 4, 10 Not applicable.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treating Acutely Agitated Patients With Asenapine Sublingual Tablets Asenapine, Placebo - Agitation | Phase 4 | Completed | Unity Health Toronto | 120 | 2012-04-01 | 2016-05-16 |
| Gene Expression Profile After Gonadotropin Releasing Hormone (GnRH) Agonist Trigger of Oocyte Maturation GnRH agonist, hCG - Endometrial Receptivity, Ovarian Hyperstimulation Syndrome | Phase 4 | Terminated | UConn Health | 7 | 2012-04-01 | 2018-11-21 |
| Trial of Temozolomide, Bevacizumab Plus Bortezomib for Recurrent Glioblastoma Multiforme Temozolomide, bevacizumab and bortezomib - Glioblastoma Multiforme | Phase 1 | Completed | Emory University | 12 | 2011-12-01 | 2016-04-27 |
| Association Between Hepatitis C Infection and Renal Cell Carcinoma Hepatitis C testing - Hepatitis C, Renal Cell Carcinoma | Completed | Henry Ford Health System | 240 | 2011-01-01 | 2014-09-17 | |
| A Study of the Safety and Efficacy of CNTO 148 (Golimumab) in Children With Juvenile Idiopathic Arthritis (JIA) and Multiple Joint Involvement Who Have Poor Response to Methotrexate (GO KIDS) CNTO 148 (Golimumab), Placebo, Methotrexate - Juvenile Idiopathic Arthritis | Phase 3 | Terminated | Janssen Research & Development, LLC | 173 | 2010-12-01 | 2016-04-04 |
| Study of Subcutaneous Golimumab in Chinese Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy Golimumab, Placebo, Methotrexate (MTX) - Rheumatoid Arthritis | Phase 3 | Completed | Centocor, Inc. | 264 | 2010-09-01 | 2013-09-06 |
| SCH-900105 in Recurrent Glioblastoma SCH 900105 - Glioblastoma | Phase 1 | Withdrawn | M.D. Anderson Cancer Center | 2010-08-01 | 2012-02-20 | |
| EXtended Therapy in Hepatitis C Genotype 3 Infected Patients Peginterferon alfa-2b (Pegetron) plus ribavirin (Rebetol) - Chronic Hepatitis C | Phase 3 | Terminated | University Health Network, Toronto | 2 | 2010-02-01 | 2011-09-29 |
| Development of an Interactive Web-based Teaching Tool for in Vitro Fertilization (IVF) Patients Knowledge Questionnaire, Perceived Stress Scale, Satisfaction questionnaire - Education | Not applicable | Unknown | Ottawa Fertility Centre | 40 | 2010-01-01 | 2010-01-15 |
| The Effects of Oral Hypoglycemic Agents on Chronic Hepatitis C Patients Receiving Peg-Intron Plus Ribavirin Pioglitazone, Acarbose, Metformin - Chronic Hepatitis C | Phase 4 | Unknown | National Taiwan University Hospital | 80 | 2009-11-01 | 2012-11-27 |
| An Effectiveness and Safety Study of Intravenous Golimumab in Patients With Active Rheumatoid Arthritis Despite Treatment With Methotrexate Therapy Golimumab, Placebo, methotrexate (MTX) - Arthritis, Rheumatoid | Phase 3 | Completed | Centocor, Inc. | 592 | 2009-09-01 | 2013-12-25 |
| Pharmacokinetics of Posaconazole Prophylaxis in Acute Leukemia Posaconazole - Leukemia, Fungal Infection | Phase 2 | Completed | M.D. Anderson Cancer Center | 25 | 2009-09-01 | 2019-02-27 |
| Pilot Study of IFN α2b for Melanoma Patients IFNα2b, PEG- IFNα2b - Melanoma | Early Phase 1 | Terminated | University of Pittsburgh | 50 | 2009-09-01 | 2017-08-04 |
| Study of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Progeria Lonafarnib, Zoledronic Acid, and Pravastatin - Progeria | Phase 2 | Unknown | Boston Children's Hospital | 85 | 2009-08-01 | 2023-02-27 |
| Study of 18F-FEC for Positron Emission Tomography-Computed Tomography (PET-CT) Imaging of GBM External-beam radiation therapy, Temozolomide - Astrocytoma, Grade IV, Giant Cell Glioblastoma | Withdrawn | Centre hospitalier de l'Université de Montréal (CHUM) | 2009-06-01 | 2020-07-23 | ||
| 5-aza-2-deoxycytidine With Pegylated Interferon-alfa 2B: A Phase I Study With Molecular Correlates Decitabine and Pegylated Interferon-Alfa 2B - Cancer | Phase 1 | Terminated | Nevada Cancer Institute | 3 | 2009-04-01 | 2011-07-20 |
| A Study of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Progeria Lonafarnib, Zoledronic Acid, Pravastatin - Progeria, Hutchinson-Gilford Syndrome | Phase 2 | Completed | Boston Children's Hospital | 5 | 2009-03-01 | 2019-06-13 |
| Effectiveness of a School-Based Hand Sanitizer Program on Reducing Asthma Exacerbations Active Hand Sanitizer - Asthma | Not applicable | Completed | University of Alabama at Birmingham | 527 | 2009-01-01 | 2017-11-27 |
| Temozolomide and Sunitinib Malate in Treating Patients With Stage III or Stage IV Malignant Melanoma sunitinib malate, temozolomide - Metastatic Melanoma | Phase 1 | Completed | Jonsson Comprehensive Cancer Center | 16 | 2008-12-01 | 2020-08-03 |
| Lonafarnib in Metastatic Breast Cancer Lonafarnib - Metastatic Breast Cancer | Phase 2 | Terminated | George Sledge | 29 | 2008-10-01 | 2016-02-18 |
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Glioblastoma (16) · Brain Neoplasms (15) · Hepatitis C (14) · HIV Infections (12) · Melanoma (12) · Glioma (11) · Gliosarcoma (11) · Hepatitis C, Chronic (9) · Acquired Immunodeficiency Syndrome (7) · Arthritis, Rheumatoid (7) · Breast Neoplasms (7) · Astrocytoma (6) · AIDS-Related Opportunistic Infections (5) · Asthma (5) · Crohn Disease (5)
Temozolomide (34) · peginterferon alfa-2b (21) · Ribavirin (12) · Ezetimibe (9) · golimumab (9) · Methotrexate (8) · lonafarnib (8) · Infliximab (7) · Interferon alpha-2 (7) · Mometasone Furoate (7) · Bevacizumab (5) · Simvastatin (5) · liposomal doxorubicin (5) · Formoterol Fumarate (4) · Introns (4)
United States (95) · Canada (21) · Germany (14) · Spain (13) · France (12) · Belgium (11) · United Kingdom (11) · Poland (8) · Australia (7) · Mexico (7) · Netherlands (7) · Argentina (6) · Austria (6) · Hungary (6) · New Zealand (5)
Ahmad Tarhini, MD (2) · Annick Desjardins, MD (2) · Katherine B Peters, MD, PhD (2) · Mark W Kieran, MD, PhD (2) · Patrick Wen, MD (2) · Paul Chapman, MD (2) · Thomas Kaley, MD (2) · AA Levine (1) · Afshin Dowlati, MD (1) · Alberto Pappo, MD (1)
PMID 27803138, PMID 30412238, PMID 20663203, PMID 21883954, PMID 24757132, PMID 24795390, PMID 27400896, PMID 28606966, PMID 36507973, PMID 36919608, PMID 17484872, PMID 17894303, PMID 17894323, PMID 17943989, PMID 18295023, PMID 18634152, PMID 18765432, PMID 19248087, PMID 19380898, PMID 19547918, PMID 19560810, PMID 19663124, PMID 20131276, PMID 20233275, PMID 20361253, PMID 20393175, PMID 20403021, PMID 20443129, PMID 20456213, PMID 20492655, PMID 20493576, PMID 20498207, PMID 20506403, PMID 20807322, PMID 20819468, PMID 20876416, PMID 20878446, PMID 20925442, PMID 20969743, PMID 21083889, PMID 21122660, PMID 21239121, PMID 21262099, PMID 21421542, PMID 21622969, PMID 21663949, PMID 21692942, PMID 21730079, PMID 21737071, PMID 21792866
2008 (2), 2004 (1), 2005 (1), 2009 (1), P30CA006516 (1), P30CA008748 (1), P30CA016672 (1), P30CA072720 (1), R01HL086972 (1), U01DK062444 (1), U01DK062467 (1), U01DK062483 (1), U01DK062484 (1), U01DK062494 (1), U01DK062496 (1)