8 completed, 1 not yet recruiting, 1 terminated, 1 unknown. 7 Not applicable, 2 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 5, Not yet recruiting 1, Unknown 1 |
| Phase 3 | 2 | Completed 2 |
| Phase 4 | 1 | Terminated 1 |
Follow Lactase: new trials by email Literature Review of Lactase trials Research Report on Lactase
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Lactase-Treated Feeds on Feeding Intolerance in Preterm Infants Lactase enzyme, Distilled water - Feeding Intolerance in Preterm Infants | Not applicable | Completed | Ain Shams University | 70 | 2025-11-20 | 2026-08-31 |
| Lactase-Assisted Control Trial On Weight GAin in INfants. Lactase - Prematurity | Not applicable | Completed | Aristotle University Of Thessaloniki | 100 | 2025-08-27 | 2026-10-08 |
| The Role of Irritable Bowel Syndrome in Lactose Intolerance (LION) alverine-citrate + simethicone and lactase, alverin-citrate + simethicone with placebo - Irritable Bowel Syndrome, Lactose Intolerance | Not applicable | Not yet recruiting | University of Pecs | 200 | 2022-09-01 | 2021-10-29 |
| Comparison of the Effectiveness of Oral Lactase Enzyme and Lactose Free Formula Lactase enzyme, Lactose-free formula feed - Secondary Lactose Intolerance | Not applicable | Completed | Muhammad Aamir Latif | 50 | 2022-06-01 | 2025-02-19 |
| Effect of a Probiotic With High Beta-galactosidase Activity on Patients With Lactose Intolerance Tropical juice with probiotics (B.coagulans), a Tropical juice with no probiotics, lactase tablet - Lactose Intolerance | Not applicable | Completed | Instituto de Investigación Hospital Universitario La Paz | 40 | 2021-02-22 | 2022-05-10 |
| Evaluation of Lactate in Patients Undergoing Glial and Non Glial Mass Surgery With Craniotomy lactate level, Glasgow Outcome Scale - Lactate, Brain Tumor | Completed | Trakya University | 100 | 2019-12-10 | 2023-01-19 | |
| Effect of Probiotic Supplementation on Lactose Maldigestion Induced by Lactose Solution Probiotic, Lactase, Placebo - Lactose Intolerance | Not applicable | Completed | Danisco | 34 | 2018-11-05 | 2019-08-13 |
| Treatment of Acute Sinusitis With High-Dose vs. Standard-Dose Amoxicillin/Clavulanate Amoxicillin 875 mg, Placebo (lactase) - Sinusitis, Acute | Phase 4 | Terminated | Paul Sorum, MD | 157 | 2018-02-26 | 2021-08-12 |
| Lactate Clearance Goal-directed Therapy in Sepsis Lactate clearance 10% target group, Lactate clearance 20% target group, Standard EGDT group - Sepsis | Not applicable | Unknown | Nanfang Hospital, Southern Medical University | 1128 | 2017-08-21 | 2017-08-22 |
| A Non-inferiority, Multicenter and Randomized, Single-Dose Study About a Treatment to Hypolactasia (LAILAI) Lactase - Hypolactasia | Phase 3 | Completed | Eurofarma Laboratorios S.A. | 140 | 2011-07-01 | 2012-06-26 |
| A Non-inferiority, Multicenter and Randomized, Multiple-Dose Study About a Treatment to Hypolactasia Lactase Oral Tablets - Lactose Intolerance | Phase 3 | Completed | Eurofarma Laboratorios S.A. | 140 | 2011-06-01 | 2012-06-28 |
Lactose Intolerance (5) · Brain Neoplasms (1) · Irritable Bowel Syndrome (1) · Postoperative Complications (1) · Premature Birth (1) · Sepsis (1) · Sinusitis (1) · Weight Gain (1)
Eurofarma Laboratorios S.A. (2) · Ain Shams University (1) · Aristotle University Of Thessaloniki (1) · Danisco (1) · Instituto de Investigación Hospital Universitario La Paz (1) · Muhammad Aamir Latif (1) · Nanfang Hospital, Southern Medical University (1) · Paul Sorum, MD (1) · Trakya University (1) · University of Pecs (1)
Brazil (2) · China (1) · Egypt (1) · France (1) · Greece (1) · Hungary (1) · Pakistan (1) · Spain (1) · Turkey (Türkiye) (1) · United States (1)
Heda Amarante, M.D (2) · Marta Machado, M.D (2) · Mauro Bafutto, M.D (2) · Sender Miszputen, M.D (2) · Wilson Catapani, M.D (2) · Carlos Fernando Francesconi, M.D (1) · Carlos Francesconi, M.D (1) · Chen Zhongqing, Ph.D (1) · Christos Tsakalidis (1) · Fatima Ghayas, FCPS (1) · Flavio Steinwurtz, MD (1) · Heena Ghayas, FCPS (1)
PMID 27144617, PMID 27706451, PMID 33755168, PMID 36149331, PMID 42668931