190 completed, 26 unknown, 15 terminated, 10 withdrawn. 259 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 259 | Completed 190, Unknown 26, Terminated 15, Withdrawn 10, Recruiting 7, Active not recruiting 6, Not yet recruiting 5 |
Follow Nose Diseases: new trials by email Literature Review of Nose Diseases trials Research Report on Nose Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparative Effectiveness of Available Treatments for Sinus and Ear Infections in Children (Acute Sinusitis) Amoxicillin, Amoxi Clavulanate, Amoxicillin Placebo - ACUTE SINUSITIS, Sinusitis | Phase 4 | Recruiting | Nader Shaikh | 1100 | 2026-10-01 | 2026-10-20 |
| A Study to Visualize Multi-Symptom Allergy in Adults With Seasonal Allergic Rhinitis Fluticasone propionate - Rhinitis Allergic, Rhinitis Seasonal | Phase 4 | Not yet recruiting | HALEON | 16 | 2026-09-01 | 2026-09-14 |
| Comparison of Antihistamine and Antileukotriene Add-On Therapy to Intranasal Corticosteroid in Allergic Rhinitis Mometasone Furoate Nasal spray, Loratadine 10 Mg, Montelukast 10 mg - Allergic Rhinitis (AR) | Phase 4 | Not yet recruiting | Liaquat National Hospital & Medical College | 32 | 2026-09-01 | 2026-04-16 |
| Evaluation of ALLERgen Specific Vaccination of DOG Allergic Patients in Swedish Practice ALK Alutard SQ Dog - Allergic Rhinitis, Asthma (Diagnosis) | Phase 4 | Recruiting | Karolinska Institutet | 40 | 2026-08-01 | 2026-06-29 |
| Efficacy and Safety of Depemokimab Monotherapy Without Concomitant Use of Intranasal Corticosteroids (INCS) in Japanese Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) Depemokimab - Nasal Polyps | Phase 4 | Recruiting | GlaxoSmithKline | 28 | 2026-07-15 | 2026-09-08 |
| Biologics in Chronic Rhinosinusitis With Nasal Polyposis Biologic Agents - Chronic Sinusitis, Nasal Polyps | Phase 4 | Recruiting | Medical University of South Carolina | 504 | 2026-06-03 | 2026-11-10 |
| Dymista in Chinese Adolescents Treatment with 137 µg azelastine hydrochloride and 50 μg of fluticasone propionate - Allergic Rhinitis Due to Allergens | Phase 4 | Completed | Viatris Inc. | 100 | 2026-05-08 | 2026-11-03 |
| The Efficacy of Local Application of B-sitosterol Versus Vasline in Cases of Idiopathic Epistaxis vasline, B-sitosterol - Epistaxis | Phase 4 | Not yet recruiting | Assiut University | 162 | 2026-05-01 | 2026-04-15 |
| A Prospective, Randomized, Controlled Study Comparing the Efficacy of Intranasal Corticosteroids (INCS) Combined With Intranasal Antihistamines (INAH) and INCS Combined With Oral Antihistamines (OAH) in the Treatment of Moderate to Severe Allergic Rhinitis Symptoms Intranasal corticosteroids (INCS) combined with oral antihistamines (OAH) used for treatment, Intranasal corticosteroids (INCS) combined with nasal antihistamines (INAH) used for treatment. - Allergic Rhinitis | Phase 4 | Not yet recruiting | China-Japan Union Hospital | 50 | 2026-01-01 | 2025-12-19 |
| Steroids for Rhinoplasty: Pain, Nausea, Edema and Ecchymosis Medrol 4 MG Oral Tablet Includes Medrol Dosepak - Edema, Bruising | Phase 4 | Withdrawn | Vanderbilt University Medical Center | 2026-01-01 | 2025-11-18 | |
| Study to Assess Safety and Efficacy of Fexofenadine Hydrochloride (HCL) + Pseudoephedrine HCL Fixed Dose Combination in Indian Male and Female Participants With Allergic Rhinitis (AR) Who Are 12 Years and Above Fexofenadine HCL and pseudoephedrine HCL - Rhinitis Allergic | Phase 4 | Completed | Sanofi | 203 | 2025-06-15 | 2026-02-17 |
| Complete Remission After Treatment With Biologics for Nasal Polyps DUPIXENT®, NUCALA®, Dupi discontinuation - Nasal Polyps | Phase 4 | Recruiting | Copenhagen University Hospital, Rigshospitalet | 66 | 2025-04-03 | 2025-12-05 |
| Evaluation of Treatments for Allergic Rhinitis (Rhinal 2) ALLERSPRAY-G (device A), PCNS (device B) - Allergic Rhinitis | Phase 4 | Completed | University Hospital, Clermont-Ferrand | 35 | 2025-03-03 | 2025-06-13 |
| Budesonide Irrigation in Allergic Rhinitis The budesonide nasal irrigation, The budesonide nasal spray - Allergic Rhinitis | Phase 4 | Not yet recruiting | Siriraj Hospital | 78 | 2025-02-12 | 2025-01-21 |
| Oxymetazoline Bridge Therapy With Intranasal Corticosteroids in Pediatric Allergic Rhinitis Mometasone Furoate (MF) Metered Dose Inhaler (MDI), 100 mcg, Oxymetazoline 0.05% nasal solution - Persistent Allergic Rhinitis | Phase 4 | Completed | Dr. Behcet Uz Children's Hospital | 76 | 2025-01-02 | 2026-05-18 |
| Tranexamic Acid Versus Blood Stopper Treatments in Epistaxis Management Blood Stopper (Ankaferd) - Epistaxis Nosebleed | Phase 4 | Unknown | Ankara Ataturk Sanatorium Training and Research Hospital | 186 | 2024-10-01 | 2024-07-08 |
| Dietary Supplement (Beta-Glucans) in Allergic Patients Undergoing Subcutaneous Immunotherapy. Specific immunotherapy (SIT) treatment, Dietary Supplement: ABB C1, Mini-tablets with pork extract - Rhinitis, Allergic Rhinoconjunctivitis | Phase 4 | Completed | Gala Servicios Clinicos S.L. | 60 | 2024-05-29 | 2025-08-29 |
| Dexmedetomidine Infusion in Either Total Intravenous Anesthesia or Inhalational Anesthesia to Improve Surgical Field Visibility in Endoscopic Sinus Surgery functional endoscopic sinus surgery, Dexmedetomidine - Rhinosinusitis | Phase 4 | Completed | Menoufia University | 50 | 2024-05-01 | 2025-09-08 |
| NOVAPAK Nasal Packing in Shellfish Allergic Patients NOVAPAK nasal packing applied to forearm, NOVAPAK nasal packing applied to nasal cavity - Shellfish Hypersensitivity, Epistaxis | Phase 4 | Unknown | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 20 | 2024-03-15 | 2023-09-11 |
| Comparison of Remimazolam and Propofol for Recovery of Ambulatory Upper Airway Surgery Remimazolam, Propofol - Laryngeal Disease, Pharyngeal Diseases | Phase 4 | Unknown | Chung-Ang University Gwangmyeong Hospital | 116 | 2024-01-22 | 2024-07-18 |
Showing 20 of 259. Sign in to see all of them.
Rhinitis, Allergic (96) · Rhinitis, Allergic, Seasonal (53) · Rhinitis, Allergic, Perennial (34) · Rhinitis (28) · Sinusitis (28) · Asthma (24) · Nasal Polyps (19) · Nasal Obstruction (17) · Rhinosinusitis (15) · Hypersensitivity (13) · Epistaxis (10) · Anosmia (3) · Bronchitis (3) · Dermatitis, Atopic (3) · Rhinorrhea (3)
Respiratory Tract Diseases (258) · Otorhinolaryngologic Diseases (257) · Immune System Diseases (176) · Hypersensitivity, Immediate (172) · Respiratory Hypersensitivity (171) · Rhinitis (169) · Hypersensitivity (162) · Rhinitis, Allergic (71) · Infections (69) · Respiratory Tract Infections (67) · Pathological Conditions, Signs and Symptoms (50) · Paranasal Sinus Diseases (39) · Lung Diseases (31) · Lung Diseases, Obstructive (29)
Fluticasone (22) · Mometasone Furoate (18) · fexofenadine (18) · levocetirizine (18) · montelukast (18) · Loratadine (12) · desloratadine (12) · Cetirizine (11) · azelastine (11) · fluticasone furoate (9) · Budesonide (8) · Sodium Chloride (8) · Amoxicillin-Potassium Clavulanate Combination (6) · Oxymetazoline (6) · Omalizumab (5)
Organon and Co (22) · GlaxoSmithKline (16) · University of Chicago (12) · Sanofi (11) · Bayer (6) · UCB Pharma (6) · University of Dundee (6) · Alcon Research (5) · Medical University of Lodz (5) · Stanford University (4) · Brian J Lipworth (3) · Washington University School of Medicine (3) · AstraZeneca (2) · Bayside Health (2) · Beijing Tongren Hospital (2)
United States (88) · Canada (20) · Italy (11) · United Kingdom (11) · China (10) · Poland (9) · Turkey (Türkiye) (6) · Germany (5) · South Korea (5) · Spain (5) · Thailand (5) · Belgium (4) · Egypt (4) · Argentina (3) · Australia (3)
Robert M Naclerio, MD (6) · Phyllis Diener (5) · Brian J Lipworth, MD (3) · Brian Lipworth, MD, FRCP (3) · Anne K Ellis, MD (2) · Brian Lipworth, MD (2) · Claus Bachert, MD, PhD (2) · Jay F Piccirillo, MD (2) · Luo Zhang (2)
PMID 20167147, PMID 20642206, PMID 11558866, PMID 16140398, PMID 16278257, PMID 16846553, PMID 16913264, PMID 17424883, PMID 18331513, PMID 18399898, PMID 18430310, PMID 18559163, PMID 18710420, PMID 19127072, PMID 19187327, PMID 19344620, PMID 19428097, PMID 19504468, PMID 19696440, PMID 19788025, PMID 19804441, PMID 19823201, PMID 20110036, PMID 20203244, PMID 20350147, PMID 20377116, PMID 20471615, PMID 20674827, PMID 20819468, PMID 21038023, PMID 21055665, PMID 21067660, PMID 21357906, PMID 21377716, PMID 21453656, PMID 21518040, PMID 21676042, PMID 21844413, PMID 22192967, PMID 22230419, PMID 22289724, PMID 22328829, PMID 22337680, PMID 23147964, PMID 23282980, PMID 23331565, PMID 23406601, PMID 23636036, PMID 23682979, PMID 23786282
2004 (2), 2005 (2), 2015 (2), R37HL068546 (1), U01AI064655 (1)