20 completed, 5 unknown, 3 recruiting, 3 terminated. 15 Not applicable, 9 Phase 2, 4 Phase 1, 1 Phase 3, 1 Phase 4.
Follow Myalgic Encephalomyelitis: new trials by email Literature Review of Myalgic Encephalomyelitis trials Research Report on Myalgic Encephalomyelitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lumbrokinase for Adults With Long Covid, Post-treatment Lyme Disease Syndrome, and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Lumbrokinase - Long Covid, Post-treatment Lyme Disease Syndrome | Phase 1 / Phase 2 | Recruiting | Icahn School of Medicine at Mount Sinai | 120 | 2024-10-09 | 2026-03-13 |
| A Feasibility Study: Assessing Photobiomodulation in Myalgic Encephalomyelitis Photobiomodulation therapy - Myalgic Encephalomyelitis, Chronic Fatigue Syndrome | Not applicable | Unknown | Quadram Institute Bioscience | 10 | 2024-04-24 | 2024-04-29 |
| Low Dose Rapamycin in ME/CFS, Long-COVID, and Other Infection Associated Chronic Conditions Rapamycin - Myalgic Encephalomyelitis, Long-COVID | Enrolling by invitation | Simmaron Research Inc. | 150 | 2023-12-11 | 2026-05-18 | |
| The Long COVID-19 Wearable Device Study Wearable device - Long COVID, Postural Orthostatic Tachycardia Syndrome | Not applicable | Recruiting | Scripps Translational Science Institute | 100500 | 2023-11-16 | 2025-05-11 |
| Effect of Stellate Ganglion Block on ME/CFS Bupivacaine Injection - Encephalomyelitis, Myalgic, Chronic Fatigue Syndrome | Phase 1 | Completed | Neuroversion, Inc. | 10 | 2023-03-15 | 2024-12-06 |
| Melatonin and Zinc Administration on Cardinal Symptoms in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome melatonin plus zinc, isomaltose and magnesium stearate - Chronic Fatigue Syndrome, Myalgic Encephalomyelitis | Not applicable | Unknown | Laboratorios Viñas, S.A. | 106 | 2022-09-05 | 2022-07-12 |
| Inspiratory Muscle Training in ME/CFS and COVID-19 Survivors Inspiratory muscle training - Myalgic Encephalomyelitis, Post-acute COVID-19 Syndrome | Not applicable | Completed | York University | 40 | 2022-05-09 | 2023-04-12 |
| A 3-day Course for CFS/ME A 3-day course, Waiting list - Chronic Fatigue Syndrome, Myalgic Encephalomyelitis | Not applicable | Recruiting | Norwegian University of Science and Technology | 100 | 2022-03-21 | 2025-11-26 |
| RESTORE ME -- RCT of Oxaloacetate on Improving Fatigue in ME/CFS Placebo, Medical Food - Anhydrous Enol-Oxaloacetate - Myalgic Encephalomyelitis, Chronic Fatigue Syndrome | Not applicable | Completed | Terra Biological LLC | 82 | 2022-03-15 | 2025-02-04 |
| Does a Technology Enabled Multi-disciplinary Team-based Care Model for the Management of Long COVID and Other Fatiguing Illnesses Improve Clinical Care of Patients and Represent a Sustainable Approach Within a Federally Qualified Health Center? Extension for Community Healthcare Outcomes - SARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis | Not applicable | Active not recruiting | Family Health Centers of San Diego | 20 | 2021-11-30 | 2025-08-06 |
| Clinical Trial to Assess the Improvement of Fatigue, Sleep Problems, Anxiety / Depression, Neurovegetatives Alterations and Quality of Life After the Administration of ImmunoVita® in Chronic Fatigue Syndrome Patients Active, Placebo - Chronic Fatigue Syndrome, Myalgic Encephalomyelitis | Not applicable | Completed | Vitae Health Innovation | 67 | 2021-11-10 | 2023-03-15 |
| Long-term Sequelae of COVID-19 (Myalgic Encephalomyelitis): An International Cross-Sectional Study This is an observational cross-sectional study, there is no need for intervention - Myalgic Encephalomyelitis | Completed | Alexandria University | 2450 | 2021-09-01 | 2025-07-03 | |
| Cardiovascular Analysis of PEM Saline Infusion - Myalgic Encephalomyelitis, Chronic Fatigue Syndrome | Not applicable | Completed | Icahn School of Medicine at Mount Sinai | 106 | 2021-08-31 | 2025-12-18 |
| A Trial of Solriamfetol in the Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Solriamfetol Oral Tablet [Sunosi], Placebo - Chronic Fatigue Syndrome, Myalgic Encephalomyelitis | Phase 4 | Completed | Rochester Center for Behavioral Medicine | 44 | 2021-04-27 | 2025-04-06 |
| Assessment of N-Acetylcysteine as Therapy for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome NAC 900mg/day, NAC 3600mg/day, NAC 0mg/day (Placebo) - Chronic Fatigue Syndrome, Myalgic Encephalomyelitis | Phase 2 | Active not recruiting | Weill Medical College of Cornell University | 95 | 2020-09-01 | 2026-06-22 |
| Effect of Probiotics in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) GutMagnific™ H., GutMagnific™ L., Placebo - Myalgic Encephalomyelitis, Chronic Fatigue Syndrome | Not applicable | Completed | ImmuneBiotech Medical Sweden AB | 74 | 2020-03-30 | 2021-10-14 |
| A Non-Interventional Pilot Study to Explore the Role of Gut Flora in ME/CFS No Intervention - Myalgic Encephalomyelitis, Chronic Fatigue Syndrome | Withdrawn | ProgenaBiome | 2020-03-02 | 2025-06-05 | ||
| The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome Pyridostigmine Bromide, Placebo - Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Chronic Fatigue Syndrome | Phase 2 | Completed | Brigham and Women's Hospital | 45 | 2020-01-14 | 2022-11-08 |
| A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease There is no intervention in this study - Gut Microbiome, Gastrointestinal Microbiome | Suspended | ProgenaBiome | 1000 | 2019-07-11 | 2026-09-21 | |
| The Comeback Study Preprocessed thawed donor FMT, Preprocessed thawed autologous FMT - Chronic Fatigue Syndrome, Myalgic Encephalomyelitis | Phase 2 | Completed | University Hospital of North Norway | 80 | 2019-02-15 | 2024-02-23 |
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Fatigue Syndrome, Chronic (36) · Fatigue (8) · Post-Acute COVID-19 Syndrome (5) · Pain (4) · Fibromyalgia (3) · Orthostatic Intolerance (3) · Postural Orthostatic Tachycardia Syndrome (3) · Anxiety Disorders (2) · Autonomic Nervous System Diseases (2) · Depression (2) · Irritable Bowel Syndrome (2) · Lyme Disease (2) · Post-Lyme Disease Syndrome (2) · Acne Vulgaris (1) · Alzheimer Disease (1)
Chronic Disease (36) · Disease Attributes (36) · Muscular Diseases (36) · Musculoskeletal Diseases (36) · Nervous System Diseases (36) · Neuroinflammatory Diseases (36) · Neuromuscular Diseases (36) · Pathologic Processes (36) · Pathological Conditions, Signs and Symptoms (36) · Encephalomyelitis (35) · Signs and Symptoms (12) · Infections (7) · Neurologic Manifestations (6) · Post-Infectious Disorders (6) · COVID-19 (5)
Exercise Test (2) · Melatonin (2) · Rituximab (2) · Zinc (2) · Bupivacaine (1) · Clonidine (1) · Control Groups (1) · Etanercept (1) · Excipients (1) · Exercise (1) · Isomaltose (1) · Low-Level Light Therapy (1) · Methods (1) · ORALIT (1) · Oxaloacetic Acid (1)
Haukeland University Hospital (3) · Icahn School of Medicine at Mount Sinai (2) · Laboratorios Viñas, S.A. (2) · Norwegian University of Science and Technology (2) · ProgenaBiome (2) · AIM ImmunoTech Inc. (1) · Alexandria University (1) · BC Women's Hospital & Health Centre (1) · Brigham and Women's Hospital (1) · Family Health Centers of San Diego (1) · Hospital Universitari Vall d'Hebron Research Institute (1) · ImmuneBiotech Medical Sweden AB (1) · Ithaca College (1) · Karolinska University Hospital (1) · LUCINDA BATEMAN, MD (1)
United States (16) · Norway (8) · Spain (4) · Canada (2) · Sweden (2) · United Kingdom (2) · Egypt (1)
Olav Mella, PhD, MD (2) · Sabine Hazan, MD (2) · Arthur J Hartz, MD, PhD (1) · Benjamin Natelson, MD (1) · Betsy Keller, Ph.D. (1) · Christian Ramers, MD (1) · David Putrino, PhD, PT (1) · David R Strayer, MD (1) · David Systrom, MD (1) · Deborah L Duricka, PhD (1) · Dikoma C. Shungu, Ph.D. (1) · Egil Fors, prof MD (1) · Geoff Moore, M.D. (1) · Gunnar Gottschalk, PhD (1)
PMID 26132314, PMID 22431963, PMID 22871021, PMID 23600892, PMID 24493300, PMID 25287104, PMID 25386668, PMID 26212172, PMID 26357864, PMID 27149955, PMID 28111818, PMID 28494812, PMID 29202780, PMID 31169386, PMID 33119613, PMID 33516248, PMID 33596913, PMID 33912079, PMID 34201806, PMID 34444817, PMID 34539356, PMID 35483736, PMID 35526605, PMID 36397426, PMID 37573421, PMID 38858151, PMID 38965566, PMID 39374820, PMID 39664752, PMID 40642241, PMID 40958377, PMID 41121328, PMID 41138391, PMID 42432754
R01NS116887 (1), R01NS117638 (1), R21AT004537 (1), R21NS094644 (1), U54NS105541 (1)