6 completed, 2 withdrawn. 4 Phase 1, 3 Not applicable, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 2, Withdrawn 2 |
| Not applicable | 3 | Completed 3 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Oxaloacetic Acid: new trials by email Literature Review of Oxaloacetic Acid trials Research Report on Oxaloacetic Acid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pharmacodynamic Analyses of Metabolic Agents Following Brain Radiation Anhydrous Enol-oxaloacetate, Best Practice, Biospecimen Collection - Malignant Central Nervous System Neoplasm | Phase 1 | Withdrawn | Mayo Clinic | 2025-10-20 | 2025-10-22 | |
| Oxaloacetate in Myasthenia Gravis Oxaloacetate, Placebo - Myasthenia Gravis | Phase 1 | Withdrawn | University of Kansas Medical Center | 2025-08-01 | 2025-07-11 | |
| REGAIN: RCT of Oxaloacetate for Fatigue in Long COVID Anhydrous Enol-Oxaloacetate, a "Medical Food", White Rice Flour - Post-COVID-19 Syndrome, Fatigue Syndrome, Chronic | Not applicable | Completed | Terra Biological LLC | 70 | 2023-06-01 | 2025-02-04 |
| RESTORE ME -- RCT of Oxaloacetate on Improving Fatigue in ME/CFS Placebo, Medical Food - Anhydrous Enol-Oxaloacetate - Myalgic Encephalomyelitis, Chronic Fatigue Syndrome | Not applicable | Completed | Terra Biological LLC | 82 | 2022-03-15 | 2025-02-04 |
| Trial of Oxaloacetate in ALS Oxaloacetic Acid - ALS | Phase 1 | Completed | Omar Jawdat | 18 | 2020-03-17 | 2024-06-06 |
| Trial of Oxaloacetate in Alzheimer's Disease (TOAD) Oxaloacetate (OAA) 1g, Oxaloacetate (OAA) 2g - Alzheimer's Disease (AD) | Phase 1 | Completed | Russell Swerdlow | 32 | 2015-10-01 | 2021-07-09 |
| Oxaloacetate Pharmacokinetics and Safety Oxaloacetate (OAA) - Alzheimer's Disease | Not applicable | Completed | Russell Swerdlow, MD | 6 | 2014-02-01 | 2014-07-24 |
| A Pilot Study of Oxaloacetate in Subjects With Treated PD Oxaloacetate (OAA), Placebo - Parkinson's Disease | Phase 2 / Phase 3 | Completed | University of Kansas Medical Center | 33 | 2012-12-01 | 2016-03-17 |
Alzheimer Disease (2) · Fatigue (2) · Fatigue Syndrome, Chronic (2) · Central Nervous System Neoplasms (1) · Myasthenia Gravis (1) · Parkinson Disease (1) · Post-Acute COVID-19 Syndrome (1)
Terra Biological LLC (2) · University of Kansas Medical Center (2) · Mayo Clinic (1) · Omar Jawdat (1) · Russell Swerdlow (1) · Russell Swerdlow, MD (1)
United States (8)
Russell Swerdlow, MD (2) · Lucinda Bateman, MD (1) · Mazen Dimachkie, MD (1) · Omar Jawdat, MD (1) · Rajesh Pahwa, MD (1) · Suzanne D Vernon, Ph.D. (1) · Terence C. Burns, MD, PhD (1)