8 recruiting, 7 completed, 3 withdrawn, 2 suspended. 6 Not applicable, 6 Phase 2, 5 Phase 1, 1 Early Phase 1, 1 Phase 3.
Follow this condition Literature Review of Post-Lyme Disease Syndrome trials Research Report on Post-Lyme Disease Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Precision Mito- Mito Map COMPASS Study Mito Map Energy Score and Home Functional Assessments - Mitochondrial Diseases, Myalgic Encephalomyelitis Chronic Fatigue Syndrome | Not yet recruiting | AI Agent Vault, Inc. d/b/a Precision Mito | 400 | 2026-11-01 | 2026-10-02 | |
| Ceftriaxone for Post-Treatment Lyme Disease Ceftriaxone treatment, Placebo - Post-Treatment Lyme Disease Syndrome | Phase 1 / Phase 2 | Withdrawn | Hackensack Meridian Health | 2026-05-14 | 2026-05-18 | |
| Transcranial Direct Current Stimulation for Post Treatment Lyme Disease Transcranial Direct Current Stimulation (tDCS), Cognitive training - Post-Treatment Lyme Disease | Not applicable | Recruiting | Columbia University | 110 | 2025-07-14 | 2026-05-06 |
| Experiences and Care Pathways Shared on Social Media Regarding 5 Conditions Causing Chronic Pain Lyme Borreliosis, Fibromyalgia | Completed | Central Hospital, Nancy, France | 501 | 2025-03-17 | 2026-10-13 | |
| Ceftriaxone Pulse Dose for Post-Treatment Lyme Disease Ceftriaxone (Rocephin®), Dextrose 5% (D5W) - Post-Treatment Lyme Disease | Early Phase 1 | Recruiting | State University of New York - Upstate Medical University | 44 | 2025-02-03 | 2026-03-19 |
| Lumbrokinase for Adults With Long Covid, Post-treatment Lyme Disease Syndrome, and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Lumbrokinase - Long Covid, Post-treatment Lyme Disease Syndrome | Phase 1 / Phase 2 | Recruiting | Icahn School of Medicine at Mount Sinai | 120 | 2024-10-09 | 2026-03-13 |
| Sana Device for Post-Treatment Lyme Disease Syndrome Chronic Pain Sana Pain Reliever, Sham SPR - Post-treatment Lyme Disease Syndrome, Chronic Pain | Not applicable | Recruiting | Icahn School of Medicine at Mount Sinai | 20 | 2024-10-04 | 2026-05-18 |
| Navigating Pregnancy and Parenthood With Lyme Disease Quantitative surveys and qualitative interview - Lyme Disease, Post Treatment Lyme Disease | Recruiting | Children's National Research Institute | 30 | 2024-03-20 | 2026-06-17 | |
| Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research Post-Acute COVID-19 Syndrome, ME/CFS | Recruiting | Brain Inflammation Collaborative | 10000 | 2023-07-05 | 2026-01-22 | |
| Pregnancy and Early Neurodevelopmental Outcomes Following In Utero Lyme Disease Exposure Neurodevelopmental assessments and follow-up - Lyme Disease, Post-Treatment Lyme Disease | Recruiting | Children's National Research Institute | 40 | 2023-07-01 | 2026-06-16 | |
| taVNS for Persistent Symptoms From Lyme Disease taVNS - Post-Treatment Lyme Disease | Not applicable | Recruiting | Columbia University | 24 | 2023-05-08 | 2026-05-06 |
| Tetracycline Treatment Tolerability Trial Tetracycline 500 Mg, Placebo - Post-Treatment Lyme Disease | Phase 2 | Completed | Johns Hopkins University | 60 | 2022-11-02 | 2026-09-28 |
| Effects of Psilocybin in Post-Treatment Lyme Disease Psilocybin - Post-Treatment Lyme Disease, Chronic Lyme Disease | Phase 1 | Completed | Johns Hopkins University | 20 | 2022-07-01 | 2025-08-20 |
| Effect of Auricular Vagal Nerve Electrical Stimulation on Post-Treatment Lyme Disease Syndrome respiratory-gated auricular vagal afferent nerve stimulation (RAVANS), Sham RAVANS - Post-Treatment Lyme Disease Syndrome | Completed | Spaulding Rehabilitation Hospital | 15 | 2022-05-31 | 2026-02-12 | |
| Meditation and Kundalini Yoga for Persistent Lyme-related Symptoms - an Online Study Meditation, Kundalini Yoga - Post-Treatment Lyme Disease | Not applicable | Withdrawn | Research Foundation for Mental Hygiene, Inc. | 2021-06-20 | 2021-11-19 | |
| A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Lyme Disease No intervention - Lyme Disease, Lyme Disease, Chronic | Withdrawn | ProgenaBiome | 2020-03-02 | 2025-06-05 | ||
| A Novel Nutraceutical to Combat Post-Lyme Disease Syndrome RLP, Placebo - Post-Lyme Disease Syndrome (PLDS) | Phase 2 / Phase 3 | Completed | Optimal Health Research | 100 | 2019-11-29 | 2021-04-12 |
| Disulfiram: A Test of Symptom Reduction Among Patients With Previously Treated Lyme Disease Disulfiram - Fatigue, Quality of Life | Phase 1 / Phase 2 | Completed | Research Foundation for Mental Hygiene, Inc. | 11 | 2019-07-31 | 2025-01-09 |
| A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease There is no intervention in this study - Gut Microbiome, Gastrointestinal Microbiome | Suspended | ProgenaBiome | 1000 | 2019-07-11 | 2026-09-21 | |
| Treating Post-Lyme Disease Syndrome With Acetogenins ReaLife+ (RLP), Inert Brown powder - Post-Lyme Disease Syndrome (PLDS) | Phase 1 / Phase 2 | Completed | Optimal Health Research | 30 | 2019-07-01 | 2020-02-11 |
Showing 20 of 22. Sign in to see all of them.
Lyme Disease (13) · Fatigue (4) · Fatigue Syndrome, Chronic (3) · Fibromyalgia (3) · Post-Acute COVID-19 Syndrome (3) · Anxiety Disorders (2) · Arthritis, Rheumatoid (2) · Celiac Disease (2) · Chronic Pain (2) · Colitis, Ulcerative (2) · Crohn Disease (2) · Depression (2) · Endometriosis (2) · Generalized Anxiety Disorder (2)
Bacterial Infections (22) · Bacterial Infections and Mycoses (22) · Borrelia Infections (22) · Chronic Disease (22) · Disease Attributes (22) · Gram-Negative Bacterial Infections (22) · Infections (22) · Pathologic Processes (22) · Pathological Conditions, Signs and Symptoms (22) · Post-Infectious Disorders (22) · Spirochaetales Infections (22) · Vector Borne Diseases (22) · Tick-Borne Diseases (20) · Lyme Disease (9) · Signs and Symptoms (8)
Meditation (2) · Ceftriaxone (1) · Cognitive Training (1) · Disulfiram (1) · Glucose (1) · Psilocybin (1) · Tetracycline (1) · Transcranial Direct Current Stimulation (1) · lumbrokinase (1)
Research Foundation for Mental Hygiene, Inc. (3) · Children's National Research Institute (2) · Columbia University (2) · Icahn School of Medicine at Mount Sinai (2) · Johns Hopkins University (2) · Optimal Health Research (2) · ProgenaBiome (2) · Spaulding Rehabilitation Hospital (2) · AI Agent Vault, Inc. d/b/a Precision Mito (1) · Brain Inflammation Collaborative (1) · Central Hospital, Nancy, France (1) · Hackensack Meridian Health (1) · State University of New York - Upstate Medical University (1)
United States (19) · France (1)
Brian A Fallon, MD (4) · Sabine Hazan, MD (2) · Albert Garcia-Romeu, PhD (1) · Andrew Friedl, MS, MBA (1) · Bindu Balani, MD (1) · Brian A. Fallon, MD (1) · David Putrino, PT, PhD (1) · David Putrino, PhD, PT (1) · Deborah Manst, MD (1) · John N. Aucott, MD (1) · Kristopher Paolino, MD (1) · Megan L Fitzgerald, PhD (1) · Nevena Zubcevik, DO (1)