27 completed, 17 recruiting, 11 unknown, 2 active not recruiting. 59 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 59 | Completed 27, Recruiting 17, Unknown 11, Active not recruiting 2, Not yet recruiting 1, Terminated 1 |
Follow Multiple System Atrophy: new trials by email Literature Review of Multiple System Atrophy trials Research Report on Multiple System Atrophy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ultra-High Resolution PET in Aging, Neurodegeneration and Psychotic Disorders UHR PET/CT scan of the brain with ¹⁸F-FDG, UHR PET/CT scan of the brain with ¹⁸F-PE2I, UHR PET/CT scan of the brain with ¹⁸F-SynVesT-1 - Alzheimer Dementia (AD), ALS - Amyotrophic Lateral Sclerosis | Not applicable | Recruiting | Universitaire Ziekenhuizen KU Leuven | 300 | 2026-02-13 | 2026-04-03 |
| Individualized Transcranial Magnetic Stimulation in Parkinsonian Disorders TMS - Parkinson's Disease, Multiple System Atrophy | Not applicable | Recruiting | Peking University First Hospital | 50 | 2025-12-22 | 2026-06-29 |
| Slowing Cognitive Decline in Alpha-synucleinopathies by Enhancing Physical Activity Increase of physical activity volume and intensity with the use of a motivational smartphone application - Parkinson Disease, Prodromal Stage | Not applicable | Recruiting | University Hospital, Bonn | 130 | 2025-12-04 | 2026-01-16 |
| Epidural Electrical Stimulation to Support Hemodynamic Management in Individuals With Parkinson's Disease ARC-IM Investigational System - Hypotension Symptomatic, Parkinson's Disease | Not applicable | Recruiting | Ecole Polytechnique Fédérale de Lausanne | 5 | 2025-07-03 | 2026-07-07 |
| Efficacy and Safety of Bilateral Cervical Lymphatic-Venous Anastomosis in the Treatment of Multiple System Atrophy Immediate LVA, Delayed LVA - Multiple System Atrophy | Not applicable | Not yet recruiting | Ruijin Hospital | 46 | 2025-07-01 | 2025-06-25 |
| Cardiovascular Function and Response to Stimulation Within the First Year After Spinal Cord Injury spinal cord transcutaneous stimulation, Ice testing - Spinal Cord Injuries (SCI), Orthostatic Hypotension, Dysautonomic | Not applicable | Recruiting | Kessler Foundation | 15 | 2025-04-01 | 2026-07-01 |
| The STAND-UP Study Angioplasty or stenting - Orthostatic Hypotension, Dysautonomic, Orthostatic Intolerance | Not applicable | Recruiting | St. Francis Hospital, New York | 100 | 2025-01-23 | 2025-09-29 |
| Parkinson Atypical Rating of Oculometric Patterns Evaluated Routinely NeuraLight PD, NeuraLight PSP, NeuraLight MSA - Parkinson Disease, Progressive Supranuclear Palsy(PSP) | Not applicable | Unknown | NeuraLight | 40 | 2024-09-10 | 2025-03-11 |
| The Use of the CUE1/CUE1+ in People With Parkinson's Disease and Related Disorders CUE1 non-invasive device, CUE1+ device active vs sham CUE1+ device - Parkinson's Disease and Parkinsonism, Progressive Supranuclear Palsy | Not applicable | Recruiting | Queen Mary University of London | 70 | 2024-03-25 | 2024-11-21 |
| Transcutaneous Spinal Cord Stimulation Home Study Spinal COrd NEuromodulation ("SCONE") Device - Spinal Cord Injuries, Multiple System Atrophy, Parkinson Variant | Not applicable | Recruiting | Michael Berger | 6 | 2024-02-15 | 2025-02-20 |
| Medical Decision Making in Multiple System Atrophy Telemedicine visits, Multidisciplinary, personalized symptomatic treatment - Multiple System Atrophy | Not applicable | Recruiting | Medical University Innsbruck | 92 | 2023-10-01 | 2025-02-05 |
| Integrated Management of Atypical Parkinsonism: A Home-based Patient-Centered Healthcare Delivery Based on Telenursing (IMPACT Study) Telemonitoring, Standard-of-care - Atypical Parkinsonism, MSA - Multiple System Atrophy | Not applicable | Active not recruiting | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | 164 | 2023-08-17 | 2026-03-27 |
| Therapeutic Education for Multiple System Atrophy (MSA) Patients and Their Caregivers Therapeutic Education Program (TEP) - Multiple System Atrophy | Not applicable | Completed | University Hospital, Toulouse | 15 | 2023-05-30 | 2026-05-06 |
| Differential Diagnosis Between Parkinson's Disease and Multiple System Atrophy Using Digital Speech Analysis - Part 2 voice recordings - Parkinson Disease, Multiple System Atrophy | Not applicable | Completed | University Hospital, Bordeaux | 28 | 2023-03-21 | 2026-06-24 |
| Unstructured Eye Tracking as a Diagnostic and Prognostic Biomarker in Parkinsonian Disorders Free-viewing eye tracking - Parkinson's Disease and Parkinsonism, Progressive Supranuclear Palsy | Not applicable | Unknown | Conor Fearon | 122 | 2022-12-01 | 2023-03-15 |
| Proactive and Integrated Management and Empowerment in Parkinson's Disease (PRIME-UK): A New Model of Care (PRIME-RCT) PRIME Parkinson Care, Usual Care - Parkinsonism | Not applicable | Completed | University of Bristol | 214 | 2022-10-28 | 2025-09-29 |
| Optimizing BCI-FIT: Brain Computer Interface - Functional Implementation Toolkit BCI-FIT multi-modal access, BCI-FIT adaptive signal modeling, BCI-FIT active querying - Amyotrophic Lateral Sclerosis, Brainstem Stroke | Not applicable | Completed | Oregon Health and Science University | 55 | 2022-07-15 | 2025-05-16 |
| CPAP for the Treatment of Supine Hypertension Active CPAP, Sham CPAP, Sleeping in a head-up tilt (HUT) position - Autonomic Failure, Pure Autonomic Failure | Not applicable | Recruiting | Vanderbilt University Medical Center | 59 | 2022-06-23 | 2026-04-07 |
| Community Outreach for Palliative Engagement -- Parkinson Disease Parkinson Disease Standard Care, Online Community-Supported Palliative Care - Parkinson Disease Dementia, Parkinson Disease | Not applicable | Active not recruiting | University of Rochester | 632 | 2022-04-26 | 2026-11-12 |
| MotIoN aDaptive Deep Brain Stimulation for MSA Deep brain stimulation - MSA - Multiple System Atrophy | Not applicable | Completed | University of Oxford | 3 | 2021-12-03 | 2025-11-17 |
Showing 20 of 59. Sign in to see all of them.
Parkinson Disease (26) · Supranuclear Palsy, Progressive (15) · Shy-Drager Syndrome (11) · Hypotension, Orthostatic (10) · Parkinsonian Disorders (10) · Pure Autonomic Failure (8) · Corticobasal Degeneration (7) · Lewy Body Disease (7) · Hypertension (5) · Alzheimer Disease (4) · Amyotrophic Lateral Sclerosis (4) · Cerebellar Ataxia (4) · Dementia (4) · Neurodegenerative Diseases (4)
Autonomic Nervous System Diseases (59) · Basal Ganglia Diseases (58) · Central Nervous System Diseases (58) · Primary Dysautonomias (58) · Brain Diseases (57) · Nervous System Diseases (57) · Movement Disorders (56) · Synucleinopathies (52) · Neurodegenerative Diseases (49) · Pathological Conditions, Signs and Symptoms (28) · Signs and Symptoms (27) · Neurologic Manifestations (25) · Cardiovascular Diseases (23) · Vascular Diseases (23) · Parkinsonian Disorders (19)
Deep Brain Stimulation (3) · Blood Specimen Collection (2) · Sugars (2) · Transcranial Direct Current Stimulation (2) · 2-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole (1) · Angioplasty (1) · Atomoxetine Hydrochloride (1) · Colonoscopy (1) · Continuous Positive Airway Pressure (1) · Diet, Gluten-Free (1) · Droxidopa (1) · Fluoxetine (1) · Levodopa (1) · Magnetic Resonance Spectroscopy (1) · Mental Status and Dementia Tests (1)
University Hospital, Bordeaux (6) · University Hospital, Toulouse (4) · Vanderbilt University Medical Center (4) · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (3) · University of Oxford (3) · Samsung Medical Center (2) · Vanderbilt University (2) · China Medical University Hospital (1) · Conor Fearon (1) · Ecole Polytechnique Fédérale de Lausanne (1) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (1) · General University Hospital, Prague (1) · Icahn School of Medicine at Mount Sinai (1) · Institut National de la Santé Et de la Recherche Médicale, France (1) · Kessler Foundation (1)
United States (14) · France (13) · United Kingdom (5) · China (4) · Italy (4) · Austria (3) · South Korea (3) · Canada (2) · Germany (2) · Belgium (1) · Czechia (1) · Indonesia (1) · Ireland (1) · Spain (1) · Sweden (1)
Italo Biaggioni, MD (6) · Alberto Benussi, MD (3) · Barbara Borroni, MD (3) · Alastair Noyce, PhD (1) · Alessandra Fanciulli, MD PhD (1) · Alex L Green, FRCS(SN) (1) · Alexander L Green, FRCS(SN) (1) · Andrei Krassioukov, MD, FRCPC (1) · Begum Unlu, PT, MSc (1) · Benzi Kluger, MD (1) · Benzi M Kluger, MD, MS (1) · Biao Chen, MD,PHD (1) · Christine Brefel-Courbon, MD (1)
PMID 33739123, PMID 12885750, PMID 15666063, PMID 23017648, PMID 24656908, PMID 28011164, PMID 28800338, PMID 29254664, PMID 30135258, PMID 32956556, PMID 34006157, PMID 34489348, PMID 34937781, PMID 36601916, PMID 37349632, PMID 37838080, PMID 37955923, PMID 38692728, PMID 39793200, PMID 39894518, PMID 40190837, PMID 40288787, PMID 40765498, PMID 41526364, PMID 41812391, PMID 41864233, PMID 42399256
2008 (1), R01HL161095 (1), R01NR016037 (1)