18 completed. 18 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 18 | Completed 18 |
Follow Lung Injury: new trials by email Literature Review of Lung Injury trials Research Report on Lung Injury
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Intrathecal Administration of Budesonide to Prevent Bronchopulmonary Dysplasia Experimental - Bronchopulmonary Dysplasia (BPD) | Phase 4 | Completed | Universitas Indonesia | 86 | 2024-11-01 | 2026-07-24 |
| THE EFFECT OF NEBULIZED AZITHROMYCIN AS THERAPY FOR BRONCHOPULMONARY DYSPLASIA Azithromycin neubilization, Lung ultrasound - Bronchopulmonary Dysplasia, Premature | Phase 4 | Completed | Alexandria University | 100 | 2024-10-02 | 2025-07-20 |
| Pragmatic Research on Diuretic Management in Early BPD Pilot Furosemide (plus potassium chloride), Placebo (plus placebo electrolyte solution) - Bronchopulmonary Dysplasia | Phase 4 | Completed | Children's Hospital Medical Center, Cincinnati | 19 | 2023-08-17 | 2026-07-14 |
| The Efect of Azithromicyn on Bronchopulmonary Displasia in Extremely Preterm and Very Preterm Infant Azithromycin Powder - Bronchopulmonary Dysplasia, Intraventricular Hemorrhage | Phase 4 | Completed | Universitas Indonesia | 120 | 2021-06-08 | 2024-03-08 |
| Sargramostim in Patients With Acute Hypoxic Respiratory Failure Due to COVID-19 (SARPAC) Sargramostim, Control - COVID-19 | Phase 4 | Completed | University Hospital, Ghent | 87 | 2020-03-24 | 2022-11-16 |
| Intratracheal Budesonide/Surfactant Prevents BPD budesonide, Saline - Respiratory Distress Syndrome, Bronchopulmonary Dysplasia | Phase 4 | Completed | Taipei Medical University | 310 | 2019-07-01 | 2023-05-30 |
| Impact of Lidocaine Administration on Postoperative Complications During Lung Resection Surgery Lidocaine, Remifentanil - Lung Diseases, Lung Inflammation | Phase 4 | Completed | Francisco Andres de la Gala | 156 | 2019-01-28 | 2021-08-25 |
| Effects of SEvoflurane on Gas Exchange and Inflammation in Patients With ARDS (SEGA Study) sevoflurane, midazolam - Acute Respiratory Distress Syndrome | Phase 4 | Completed | University Hospital, Clermont-Ferrand | 50 | 2014-04-01 | 2026-04-21 |
| Preterm Infant Inhaled Albuterol Dosing Varied albuterol dose response - Bronchopulmonary Dysplasia, Very Low Birth Weight | Phase 4 | Completed | Oregon Health and Science University | 14 | 2013-10-24 | 2019-05-23 |
| Lung Lavage With Dilute Poractant Alfa for Meconium Aspiration Syndrome Lung lavage with surfactant, Bolus surfactant - Meconium Aspiration Syndrome | Phase 4 | Completed | Zekai Tahir Burak Women's Health Research and Education Hospital | 30 | 2013-09-01 | 2016-08-03 |
| Azithromycin in the Prevention of Lung Injury in Premature Newborn Azithromycin, Placebo - Bronchopulmonary Dysplasia | Phase 4 | Completed | Hospital de Clinicas de Porto Alegre | 80 | 2012-08-28 | 2018-04-02 |
| Oral Sildenafil in Persistent Pulmonary Hypertension Secondary to Meconium Aspiration Syndrome in Newborns Oral Sildenafil, Placebo (distilled water) - Meconium Aspiration Syndrome, Persistent Pulmonary Hypertension of Newborn | Phase 4 | Completed | Sir Takhtasinhji General Hospital | 96 | 2011-12-01 | 2022-05-20 |
| Laryngoscope Versus CMAC for Endotracheal Intubation in Patients Undergoing Emergent Airway Management CMAC videolaryngoscope, Direct Laryngoscopy - Acute Respiratory Distress | Phase 4 | Completed | Hennepin Healthcare Research Institute | 198 | 2011-10-01 | 2019-03-15 |
| Exogenous Surfactant in Very Preterm Neonates in Prevention of Bronchopulmonary Dysplasia Curosurf, Air - Infant, Premature, Diseases, Respiratory Distress Syndrome, Newborn | Phase 4 | Completed | Jean Michel Hascoet | 118 | 2009-12-01 | 2022-08-24 |
| Sleep Intervention During Acute Lung Injury Dexmedetomidine, Midazolam and Fentanyl - Critical Illness, Sleep | Phase 4 | Completed | University of Arizona | 90 | 2009-08-01 | 2021-08-04 |
| The Role of Anti-Reflux Surgery for Gastroesophageal Reflux Disease in Premature Infants With Bronchopulmonary Dysplasia Fundoplication - Gastroesophageal Reflux Disease, Bronchopulmonary Dysplasia | Phase 4 | Completed | The University of Texas Health Science Center, Houston | 2 | 2009-06-01 | 2014-12-11 |
| Recruitment Maneuver After Intubation Recruitment maneuver - Hypoxemia | Phase 4 | Completed | University Hospital, Clermont-Ferrand | 40 | 2008-12-01 | 2009-11-25 |
| Study of Sivelestat Sodium Hydrate in Acute Lung Injury (ALI) Associated With Systemic Inflammatory Response Syndrome (SIRS) in Japan Sivelestat sodium hydrate - Acute Lung Injury, Systemic Inflammatory Response Syndrome | Phase 4 | Completed | Ono Pharmaceutical Co., Ltd. | 649 | 2004-06-01 | 2015-04-23 |
Bronchopulmonary Dysplasia (9) · Acute Lung Injury (6) · Respiratory Distress Syndrome (4) · Hypoxia (2) · Lung Diseases (2) · Meconium Aspiration Syndrome (2) · Respiratory Aspiration (2) · COVID-19 (1) · Critical Illness (1) · Disease (1) · Dyspnea (1) · Enterocolitis, Necrotizing (1) · Gastroesophageal Reflux (1) · Hypertension, Pulmonary (1)
Respiratory Tract Diseases (17) · Lung Diseases (16) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (11) · Infant, Newborn, Diseases (11) · Pathological Conditions, Signs and Symptoms (10) · Infant, Premature, Diseases (8) · Respiration Disorders (8) · Ventilator-Induced Lung Injury (8) · Pathologic Processes (7) · Female Urogenital Diseases and Pregnancy Complications (3) · Pregnancy Complications (3) · Signs and Symptoms (3) · Signs and Symptoms, Respiratory (3) · Urogenital Diseases (3)
Midazolam (2) · poractant alfa (2) · Air (1) · Albuterol (1) · Azithromycin (1) · Bronchoalveolar Lavage (1) · Budesonide (1) · Dexmedetomidine (1) · Fentanyl (1) · Fundoplication (1) · Furosemide (1) · Lidocaine (1) · Procaterol (1) · Remifentanil (1) · Sevoflurane (1)
Universitas Indonesia (2) · University Hospital, Clermont-Ferrand (2) · Alexandria University (1) · Children's Hospital Medical Center, Cincinnati (1) · Francisco Andres de la Gala (1) · Hennepin Healthcare Research Institute (1) · Hospital de Clinicas de Porto Alegre (1) · Jean Michel Hascoet (1) · Ono Pharmaceutical Co., Ltd. (1) · Oregon Health and Science University (1) · Sir Takhtasinhji General Hospital (1) · Taipei Medical University (1) · The University of Texas Health Science Center, Houston (1) · University Hospital, Ghent (1) · University of Arizona (1)
United States (5) · France (3) · Indonesia (2) · Belgium (1) · Egypt (1) · India (1) · Japan (1) · Spain (1) · Taiwan (1) · Turkey (Türkiye) (1)
Adhi Teguh Perma Iskandar, Dr. dr. Sp. A(K) (1) · Amanda Kim, MD (1) · Anna Maria Hibbs, MD, MSCE (1) · Bart Lambrecht (1) · Cynthia McEvoy, MD, MCR (1) · Evelyn Phangkawira, dr. Sp. A (1) · Francisco de la Gala, MD PhD (1) · Heather Kaplan, MD, MSCE (1) · James R Miner, MD (1) · Jayendra R Gohil, MD (1) · KuoJen Tsao, M.D. (1) · Project Leader, Development Planning (1)
PMID 18426851, PMID 20138301, PMID 20426859, PMID 26351971, PMID 26850232, PMID 26928567, PMID 27611637, PMID 29193276, PMID 30690595, PMID 31694684, PMID 32503663, PMID 32559419, PMID 32894857, PMID 36459994, PMID 40897588
2009 (1), R01HL095748 (1), R34HL158586 (1)