18 completed, 10 unknown, 2 not yet recruiting, 2 recruiting. 33 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 33 | Completed 18, Unknown 10, Not yet recruiting 2, Recruiting 2, Terminated 1 |
Follow Lung Injury: new trials by email Literature Review of Lung Injury trials Research Report on Lung Injury
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of Higher Zinc Supplementation on Neonatal Weight Velocity 1 mg/day Zinc Supplementation, 3 mg/day Zinc Supplementation - Extreme Prematurity,Extremely Low Birthweight, BPD - Bronchopulmonary Dysplasia | Phase 4 | Recruiting | Augusta University | 30 | 2026-08-01 | 2026-10-26 |
| Perioperative Lidocaine for Lung Protection in Infants Undergoing Cardiac Surgery Lidocaine %2 ampoule, Normal Saline (0.9% NaCl) - Congenital Heart Disease, Postoperative Pulmonary Complications | Phase 4 | Not yet recruiting | The Children's Hospital of Zhejiang University School of Medicine | 320 | 2026-04-01 | 2026-03-30 |
| Ciprofol's Impact on Oxygenator Function in Extracorporeal Membrane Oxygenation (ECMO) Patients Ciprofol, Midazolam - ECMO Treatment, ARDS (Acute Respiratory Distress Syndrome) | Phase 4 | Not yet recruiting | First Affiliated Hospital of Wannan Medical College | 30 | 2025-05-01 | 2025-04-18 |
| Enteral Lipid Supplementation and Bronchoplumonary Dysplasia of Premature Infants Enteral supplementation with ARA and DHA (in a 2:1 ratio) in addition to standard care and feeding, Standard care and feeding - Bronchopulmonary Dysplasia (BPD) | Phase 4 | Recruiting | Aristotle University Of Thessaloniki | 74 | 2025-03-04 | 2026-06-17 |
| Efficacy of Intrathecal Administration of Budesonide to Prevent Bronchopulmonary Dysplasia Experimental - Bronchopulmonary Dysplasia (BPD) | Phase 4 | Completed | Universitas Indonesia | 86 | 2024-11-01 | 2026-07-24 |
| THE EFFECT OF NEBULIZED AZITHROMYCIN AS THERAPY FOR BRONCHOPULMONARY DYSPLASIA Azithromycin neubilization, Lung ultrasound - Bronchopulmonary Dysplasia, Premature | Phase 4 | Completed | Alexandria University | 100 | 2024-10-02 | 2025-07-20 |
| Pragmatic Research on Diuretic Management in Early BPD Pilot Furosemide (plus potassium chloride), Placebo (plus placebo electrolyte solution) - Bronchopulmonary Dysplasia | Phase 4 | Completed | Children's Hospital Medical Center, Cincinnati | 19 | 2023-08-17 | 2026-07-14 |
| The Caffeine Therapy in the Fetal to Neonatal Transition Early Caffeine administration, Control Group - Mechanical Ventilation Complication, Caffeine | Phase 4 | Unknown | Hospital de Clinicas de Porto Alegre | 50 | 2022-04-27 | 2025-04-02 |
| Continuous Infusion Versus Intermittent Boluses of Cisatracurium in the Early Management of Pediatric ARDS Intermittent boluses of Cisatracurium, Intravenous infusion of Cisatracurium for 24 hours - Respiratory Distress Syndrome, Pediatric, Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) | Phase 4 | Unknown | Tanta University | 60 | 2022-01-06 | 2022-06-22 |
| The Efect of Azithromicyn on Bronchopulmonary Displasia in Extremely Preterm and Very Preterm Infant Azithromycin Powder - Bronchopulmonary Dysplasia, Intraventricular Hemorrhage | Phase 4 | Completed | Universitas Indonesia | 120 | 2021-06-08 | 2024-03-08 |
| Nebulized Heparin for the Treatment of COVID-19 Induced Lung Injury Heparin, 0.9% Sodium-chloride - Covid-19, ARDS, Human | Phase 4 | Terminated | Frederick Health | 13 | 2020-06-01 | 2024-04-03 |
| Sargramostim in Patients With Acute Hypoxic Respiratory Failure Due to COVID-19 (SARPAC) Sargramostim, Control - COVID-19 | Phase 4 | Completed | University Hospital, Ghent | 87 | 2020-03-24 | 2022-11-16 |
| Intra-tracheal Instillation of Budesonide to Prevent Chronic Lung Disease Infants in the study group (S/B group) will receive surfactant 2.5 mls/kg and Budesonide 0.5 mg (1mL), Infants in the control group (S/P group) receive placebo (Normal saline 1mL) - Infant, Extremely Premature, Acute Lung Injury | Phase 4 | Unknown | University of Arizona | 25 | 2019-12-02 | 2022-11-01 |
| Zinc Supplementation on Very Low Birth Weight Infant Zinc Sulfate, Placebos - Early-Onset Sepses, Neonatal, Periventricular Haemorrhage Neonatal | Phase 4 | Unknown | Fakultas Kedokteran Universitas Indonesia | 364 | 2019-08-20 | 2019-08-15 |
| Intratracheal Budesonide/Surfactant Prevents BPD budesonide, Saline - Respiratory Distress Syndrome, Bronchopulmonary Dysplasia | Phase 4 | Completed | Taipei Medical University | 310 | 2019-07-01 | 2023-05-30 |
| Impact of Lidocaine Administration on Postoperative Complications During Lung Resection Surgery Lidocaine, Remifentanil - Lung Diseases, Lung Inflammation | Phase 4 | Completed | Francisco Andres de la Gala | 156 | 2019-01-28 | 2021-08-25 |
| Oxygenation Targets in Cardiac Surgery Patients - a Before-and-after Study Oxygen - Hyperoxia, Cardiac Surgery | Phase 4 | Unknown | Aalborg University Hospital | 50 | 2018-10-01 | 2019-10-28 |
| Efficacy of Adding Budesonide to Poractant Alfa to Prevent Bronchopulmonary Dysplasia. Budesonide, Poractant Alfa, Saline - Bronchopulmonary Dysplasia, Infant,Premature | Phase 4 | Unknown | Hospital Central "Dr. Ignacio Morones Prieto" | 108 | 2018-01-01 | 2019-08-07 |
| Early Caffeine in Preterm Neonates Caffeine Citrate, Placebo (Normal Saline) - BPD - Bronchopulmonary Dysplasia, Apnea of Prematurity | Phase 4 | Unknown | Jennifer Shepherd | 24 | 2017-02-01 | 2021-08-03 |
| Effects of SEvoflurane on Gas Exchange and Inflammation in Patients With ARDS (SEGA Study) sevoflurane, midazolam - Acute Respiratory Distress Syndrome | Phase 4 | Completed | University Hospital, Clermont-Ferrand | 50 | 2014-04-01 | 2026-04-21 |
Showing 20 of 33. Sign in to see all of them.
Bronchopulmonary Dysplasia (19) · Acute Lung Injury (12) · Respiratory Distress Syndrome (8) · Premature Birth (5) · COVID-19 (2) · Enterocolitis, Necrotizing (2) · Hypoxia (2) · Lung Diseases (2) · Meconium Aspiration Syndrome (2) · Respiratory Aspiration (2) · Apnea (1) · Critical Illness (1) · Disease (1) · Dyspnea (1)
Respiratory Tract Diseases (32) · Lung Diseases (31) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (22) · Infant, Newborn, Diseases (21) · Infant, Premature, Diseases (18) · Ventilator-Induced Lung Injury (18) · Pathological Conditions, Signs and Symptoms (15) · Respiration Disorders (13) · Pathologic Processes (10) · Female Urogenital Diseases and Pregnancy Complications (7) · Pregnancy Complications (7) · Urogenital Diseases (7) · Obstetric Labor Complications (5) · Obstetric Labor, Premature (5)
Budesonide (4) · Saline Solution (4) · Midazolam (3) · Sodium Chloride (3) · poractant alfa (3) · Air (2) · Surface-Active Agents (2) · (2-(1R)-1-cyclopropyl)ethyl-6-isopropyl-phenol (1) · Albuterol (1) · Azithromycin (1) · Bronchoalveolar Lavage (1) · Control Groups (1) · Dexmedetomidine (1) · Fentanyl (1) · Fundoplication (1)
Hospital de Clinicas de Porto Alegre (2) · Universitas Indonesia (2) · University Hospital, Clermont-Ferrand (2) · University of Arizona (2) · Zekai Tahir Burak Women's Health Research and Education Hospital (2) · Aalborg University Hospital (1) · Alexandria University (1) · Aristotle University Of Thessaloniki (1) · Augusta University (1) · Children's Hospital Medical Center, Cincinnati (1) · China Medical University, China (1) · Fakultas Kedokteran Universitas Indonesia (1) · First Affiliated Hospital of Wannan Medical College (1) · Francisco Andres de la Gala (1) · Frederick Health (1)
United States (10) · France (3) · Turkey (Türkiye) (3) · China (2) · Egypt (2) · Indonesia (2) · Australia (1) · Belgium (1) · Brazil (1) · Denmark (1) · Greece (1) · India (1) · Israel (1) · Japan (1) · Mexico (1)
Adhi Teguh Perma Iskandar, Dr. dr. Sp. A(K) (1) · Amanda Kim, MD (1) · Anna Maria Hibbs, MD, MSCE (1) · Bart Lambrecht (1) · Bodil S Rasmussen, MD (1) · Cynthia McEvoy, MD, MCR (1) · Evelyn Phangkawira, dr. Sp. A (1) · Francisco de la Gala, MD PhD (1) · Heather Kaplan, MD, MSCE (1) · Henri Azis, Master (1) · James R Miner, MD (1) · Jayendra R Gohil, MD (1) · Jennifer L Shepherd, MD (1)
PMID 26351971, PMID 18426851, PMID 20084586, PMID 20138301, PMID 20426859, PMID 25164872, PMID 26053233, PMID 26850232, PMID 26928567, PMID 27611637, PMID 29193276, PMID 30690595, PMID 31694684, PMID 32503663, PMID 32559419, PMID 32894857, PMID 33502773, PMID 35244208, PMID 36459994, PMID 40897588
2009 (1), R01HL095748 (1), R34HL158586 (1)