49 completed, 15 unknown, 4 terminated, 3 not yet recruiting. 43 Not applicable, 14 Phase 2, 10 Phase 3, 6 Phase 4, 5 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Artificially Intelligent Robot Control Artificially Intelligent Robot (AIR) Control Intervention, Standard Asthma Education - Asthma in Children, Artificial Intelligence | Not applicable | Not yet recruiting | University of Miami | 80 | 2026-10-01 | 2026-09-16 |
| Efficacy of EMONO as an add-on Therapy to Conventional Antidepressants for the Treatment of Depressive Symptoms in Nursing-home Residents With Neurocognitive Disorders: a Randomized Controlled Trial- EMONO, Medical air - Depression, Neurocognitive Disorders | Phase 2 | Not yet recruiting | University Hospital, Tours | 96 | 2026-09-01 | 2026-06-17 |
| Air Tamponade Versus Fluorinated Gas Tamponade for Rhegmatogenous Retinal Detachment air, Gas SF6 (Sulfur Hexafluoride) and others - Retinal Detachment Rhegmatogenous | Not applicable | Not yet recruiting | Liverpool University Hospitals NHS Foundation Trust | 150 | 2026-03-20 | 2025-12-24 |
| AIR Support: Artificially Intelligent Robot (AIR) Support for Pediatric Asthma Education Standard Asthma Education, Artificially Intelligent Robot (AIR) Support Intervention - Asthma in Children, Artificial Intelligence | Not applicable | Completed | University of Miami | 98 | 2026-02-10 | 2026-06-22 |
| Nitrous Oxide and EMOtional Cognition Entonox, Medical Air - Depression | Not applicable | Recruiting | University of Oxford | 88 | 2024-07-10 | 2025-07-31 |
| Treatment of Suicidal Ideation in the Emergency Department Using Nitrous Oxide Nitrous oxide, Medical air - Suicidal Ideation, Emergency Psychiatric | Phase 2 | Unknown | University Hospital, Tours | 30 | 2024-06-01 | 2024-06-07 |
| Room Air a Safe Alternative to Dye Injection in Ureterography air injection - Ureteral Obstruction | Not applicable | Unknown | Assiut University | 24 | 2023-10-29 | 2023-10-31 |
| Comparing Endotracheal Tube Cuff Pressure in Laparoscopic Abdominal Surgery: Saline vs. Air Inflation Endotracheal intubation using an endotracheal tube with cuff inflated with air, Endotracheal intubation using an endotracheal tube with cuff inflated with saline - Endotracheal Intubation | Not applicable | Completed | Cukurova University | 60 | 2023-09-27 | 2023-12-13 |
| Retraining of the Amygdala and Insula for the Treatment of Persistent Covid AIR + Mindfulness, Relaxation condition - Mental Health Wellness | Not applicable | Completed | Hospital Miguel Servet | 120 | 2023-09-01 | 2025-09-16 |
| A Clinical Study of Inhaled Nitric Oxide in Moderate-to-Severe Chronic Obstructive Pulmonary Disease Inhaled nitric oxide (NO), air - Chronic Obstructive Pulmonary Disease | Not applicable | Recruiting | The First Affiliated Hospital with Nanjing Medical University | 24 | 2023-06-01 | 2025-06-18 |
| In Vivo Pulse Oximeter Validation Study Mixtures of nitrogen, air, and carbon dioxide - Hypoxia | Not applicable | Completed | Gabi SmartCare | 12 | 2023-02-28 | 2024-12-12 |
| Neuromuscular Fatigue During Exercise in COPD-HF Overlap Medical air, Hyperoxia - Pulmonary Disease, Chronic Obstructive, Heart Failure | Not applicable | Unknown | University Hospital, Grenoble | 40 | 2023-02-21 | 2024-06-24 |
| Hyperoxia Induced Pulmonary Inflammation and Organ Injury: a Human in Vivo Model Liquid oxygen, medical air - Oxygen Toxicity, Pulmonary Injury | Not applicable | Unknown | Belfast Health and Social Care Trust | 53 | 2022-12-02 | 2024-01-29 |
| How Urban Interventions in Lower Socioeconomic Areas Influence Health Behaviors (UrbASanté Study) Questionnaire, Food diary supply, Interviews (semi-structured) - Health-Related Behavior | Recruiting | Paris 12 Val de Marne University | 400 | 2022-06-01 | 2025-07-31 | |
| Inhaled Nitric Oxide (iNO) in Idiopathic Pulmonary Fibrosis (IPF). Nitric Oxide, Medical air - Idiopathic Pulmonary Fibrosis | Early Phase 1 | Unknown | Dr. Denis O'Donnell | 40 | 2022-04-21 | 2024-04-03 |
| Diaphragm Function and Diver Endurance Carbon monoxide 200 ppm in air - Respiratory Muscles | Not applicable | Completed | Duke University | 45 | 2022-04-14 | 2024-06-13 |
| Limitation of the Ventilatory Response to Exercise in the Master Athlete Heliox, Air - Healthy Volunteers | Not applicable | Terminated | Centre Hospitalier Universitaire de Nice | 3 | 2022-04-01 | 2023-09-08 |
| Supplemental Oxygen in Hypovolemia Oxygen gas, Air - Hypovolemia, Hyperoxia | Phase 1 | Completed | Oslo University Hospital | 15 | 2021-11-26 | 2022-07-05 |
| Nitrous Oxide for Late-Life Depression - PROTO-BRAIN EMONO, Medical Air - Late-Life Depression, Resistant Depression, Treatment | Not applicable | Completed | University Hospital, Tours | 60 | 2021-11-16 | 2025-11-24 |
| Voice Therapy With a Semi-occluded Vocal Tract Straw phonation in air, straw phonation in water, /u/ phonation - Voice Disorders | Not applicable | Completed | University Ghent | 58 | 2021-10-07 | 2024-10-30 |
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Pulmonary Disease, Chronic Obstructive (6) · Bronchopulmonary Dysplasia (3) · Idiopathic Pulmonary Fibrosis (3) · Migraine Disorders (3) · Pain (3) · Abdominal Pain (2) · Acute Pain (2) · Depression (2) · Dyspnea (2) · Headache (2) · Hypoxia (2) · Motor Activity (2) · Premature Birth (2) · Respiratory Distress Syndrome (2) · Retinal Detachment (2)
George Papanicolaou Hospital (3) · Schön Klinik Berchtesgadener Land (3) · University Hospital, Tours (3) · University Hospital, Toulouse (2) · University Medical Centre Ljubljana (2) · University of Miami (2) · University of Oxford (2) · Aier School of Ophthalmology, Central South University (1) · Air Liquide SA (1) · Air Liquide Santé International (1) · Assistance Publique Hopitaux De Marseille (1) · Assiut University (1) · Belfast Health and Social Care Trust (1) · Brigham and Women's Hospital (1) · Capnia, Inc. (1)
United States (18) · France (14) · United Kingdom (7) · Germany (6) · Canada (4) · Belgium (3) · China (3) · Greece (3) · Sweden (3) · Italy (2) · Slovenia (2) · Thailand (2) · Uganda (2) · Australia (1) · Austria (1)
Cynthia L Foronda, PhD (2) · Aikaterini Markopoulou, MD, PhD (1) · Amy Abernethy, MD (1) · Anil Gupta, MD, PhD (1) · Benno von Bormann, MD (1) · Benoit Conti (1) · Boris D Veysman, M.D. (1) · Chinenye R Dike, MD (1) · Craig J Railton, MD, PhD (1) · Cristina Geroldi, MD (1) · Danny McAuley, MD (1) · Data Santorino, MD (1)
PMID 26363332, PMID 19523621, PMID 20816546, PMID 20937993, PMID 21245991, PMID 22264664, PMID 23406077, PMID 24486835, PMID 25811584, PMID 26056838, PMID 26351971, PMID 26928567, PMID 27464582, PMID 27794080, PMID 27940278, PMID 29193276, PMID 30139771, PMID 31630398, PMID 32408387, PMID 33044394, PMID 33957299, PMID 34274251, PMID 35050957, PMID 36821847, PMID 36922807, PMID 37946190, PMID 37947905, PMID 39939102, PMID 40069946, PMID 42005916, PMID 42722424, PMID 6780678
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