13 completed, 4 terminated, 3 withdrawn, 2 unknown. 14 Not applicable, 5 Phase 3, 2 Phase 2, 2 Phase 4.
Follow Meconium Aspiration Syndrome: new trials by email Literature Review of Meconium Aspiration Syndrome trials Research Report on Meconium Aspiration Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| CAffeine Use in Prolonged Oxygen Use in meConium aspIration Syndrome in Neonatal Outcomes (CAPUCINO) Caffeine citrate, Saline (NaCl 0,9 %) (placebo) - Meconium Aspiration Syndrome | Phase 2 | Not yet recruiting | University of Alberta | 20 | 2026-09-01 | 2026-06-01 |
| Predicting the Need for Prolonged Respiratory Support in Neonates Delivered in a Lower-Level NICU Setting Respiratory Distress Syndrome, Newborn, Respiratory Distress Syndrome in Premature Infant | Recruiting | Mayo Clinic | 500 | 2026-03-11 | 2026-03-18 | |
| Efficacy of Nebulised Inhalational Steroids in Neonates With Meconium Aspiration Syndrome Budesonide, Normal Saline - Meconium Aspiration Syndrome | Phase 3 | Completed | Khyber Teaching Hospital | 60 | 2025-11-28 | 2026-08-13 |
| Interleukin-6 in the Development of Meconium Aspiration Syndrome in Newborn serum interleukin 6 - Meconium Aspiration Syndrome | Not applicable | Completed | Benha University | 120 | 2023-01-01 | 2026-02-06 |
| Early Bolus Surfactant Replacement Therapy Versus Standard Care in Term Neonates With Meconium Aspiration Syndrome Bovine surfactant - Meconium Aspiration Syndrome, Surfactant Dysfunction | Not applicable | Completed | Lady Hardinge Medical College | 60 | 2022-03-12 | 2024-07-09 |
| Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing Abnormalities Room air - Perinatal Death, Respiratory Distress Syndrome, Newborn | Not applicable | Withdrawn | Loma Linda University | 2021-06-01 | 2021-08-17 | |
| Time of Positive Pressure Ventilation in Non-vigorous Infants Born Through Meconium-stained Amniotic Fluid Endotracheal suctioning, No endotracheal suctioning - Meconium Aspiration Syndrome, Infant, Newborn, Disease | Not applicable | Completed | University Hospital Padova | 40 | 2019-09-16 | 2020-04-06 |
| Meconium Aspiration and Tracheal Suctioning-Feasibility Study Immediate intubation, Immediate resuscitation - Meconium Aspiration Syndrome | Not applicable | Withdrawn | St. Louis University | 2019-07-01 | 2019-07-31 | |
| Pulmonary Function Using Non-invasive Forced Oscillometry Non-invasive forced airway oscillometry - Infant, Premature, Diseases, Infant, Newborn, Diseases | Not applicable | Active not recruiting | University of Alabama at Birmingham | 600 | 2017-12-06 | 2026-01-27 |
| High Flow Ventilation With Volume Guarantee HFV + and - VG - Rds, Pulmonary Hypertension | Not applicable | Unknown | Oslo University Hospital | 15 | 2015-11-01 | 2015-10-08 |
| Helium Oxygen Mixture in the Treatment of Meconium Aspiration Syndrome helium oxygen mixture - Neonatal Meconium Aspiration | Not applicable | Completed | Ma Juan | 60 | 2015-02-01 | 2020-01-07 |
| Lung Lavage With Dilute Poractant Alfa for Meconium Aspiration Syndrome Lung lavage with surfactant, Bolus surfactant - Meconium Aspiration Syndrome | Phase 4 | Completed | Zekai Tahir Burak Women's Health Research and Education Hospital | 30 | 2013-09-01 | 2016-08-03 |
| Role of Endotracheal Suction on the Occurrence of Meconium Aspiration Syndrome in Non-vigorous Meconium Stained Babies No endotracheal suction - Meconium Aspiration Syndrome | Not applicable | Completed | Lady Hardinge Medical College | 175 | 2012-05-01 | 2014-07-10 |
| Oral Sildenafil in Persistent Pulmonary Hypertension Secondary to Meconium Aspiration Syndrome in Newborns Oral Sildenafil, Placebo (distilled water) - Meconium Aspiration Syndrome, Persistent Pulmonary Hypertension of Newborn | Phase 4 | Completed | Sir Takhtasinhji General Hospital | 96 | 2011-12-01 | 2022-05-20 |
| Comparison Of Surfactant Lung Lavage With Standard Care In The Treatment Of Meconium Aspiration Syndrome Bovine surfactant - Meconium Aspiration Syndrome | Not applicable | Completed | Lady Hardinge Medical College | 60 | 2011-01-01 | 2014-07-15 |
| Efficacy and Safety of Gastric Suctioning During Neonatal Resuscitation Gastric suctioning - Respiratory Distress | Not applicable | Terminated | Benjamin T. Stevens | 173 | 2008-08-01 | 2017-03-13 |
| Effect Of Intrapartum Oropharyngeal (IP-OP) Suction on Meconium Aspiration Syndrome Intrapartum Oropharyngeal Suctioning - Meconium Aspiration Syndrome | Not applicable | Completed | Lady Hardinge Medical College | 540 | 2008-05-01 | 2015-09-29 |
| Inhaled PGE1 in Neonatal Hypoxemic Respiratory Failure Inhaled Prostaglandin E1 - Infant, Newborn, Respiratory Insufficiency | Phase 2 | Withdrawn | NICHD Neonatal Research Network | 2008-05-01 | 2019-03-22 | |
| Use of Heliox in the Management of Neonates With Meconium Aspiration Syndrome Heliox mechanical ventilation - Meconium Aspiration Syndrome | Not applicable | Completed | Poznan University of Medical Sciences | 8 | 2006-12-01 | 2011-01-12 |
| Antibody Secreting Cell and Cyotokine Profiles in Neonates on ECMO Persistent Fetal Circulation Syndrome, Diaphragmatic Hernia | Completed | The University of Texas Health Science Center, Houston | 12 | 2006-09-01 | 2020-11-05 |
Showing 20 of 25. Sign in to see all of them.
Respiratory Distress Syndrome, Newborn (6) · Hypertension, Pulmonary (5) · Persistent Fetal Circulation Syndrome (5) · Respiratory Insufficiency (3) · Dyspnea (2) · Methemoglobinemia (2) · Pneumonia, Aspiration (2) · Respiratory Distress Syndrome (2) · Transient Tachypnea of the Newborn (2) · Acute Lung Injury (1) · Asphyxia Neonatorum (1) · Birth Injuries (1) · Bronchopulmonary Dysplasia (1) · Disease (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (25) · Female Urogenital Diseases and Pregnancy Complications (25) · Fetal Diseases (25) · Lung Diseases (25) · Lung Injury (25) · Pregnancy Complications (25) · Respiration Disorders (25) · Urogenital Diseases (25) · Infant, Newborn, Diseases (24) · Respiratory Tract Diseases (24) · Pathological Conditions, Signs and Symptoms (9) · Cardiovascular Diseases (6) · Vascular Diseases (6) · Hypertension (5) · Infant, Premature, Diseases (5)
Surface-Active Agents (2) · Alprostadil (1) · Bronchoalveolar Lavage (1) · Budesonide (1) · Labor, Induced (1) · Saline Solution (1) · Sildenafil Citrate (1) · Sodium Chloride (1) · Standard of Care (1) · Water (1) · caffeine citrate (1) · integra artificial skin (1) · lucinactant (1) · poractant alfa (1)
Lady Hardinge Medical College (4) · NICHD Neonatal Research Network (3) · Benha University (1) · Benjamin T. Stevens (1) · Khyber Teaching Hospital (1) · Loma Linda University (1) · Ma Juan (1) · Mayo Clinic (1) · Oslo University Hospital (1) · Poznan University of Medical Sciences (1) · Sir Takhtasinhji General Hospital (1) · St. Louis University (1) · St. Olavs Hospital (1) · The Hospital for Sick Children (1) · The University of Texas Health Science Center, Houston (1)
United States (9) · India (5) · Canada (2) · China (1) · Egypt (1) · Italy (1) · Norway (1) · Pakistan (1) · Poland (1) · Turkey (Türkiye) (1)
Seetha Shankaran, MD (3) · Sushma Nangia, MBBS, MD, DM (3) · Avroy A. Fanaroff, MD (2) · Edward F. Donovan, MD (2) · Krisa P. Van Meurs, MD (2) · Lu-Ann Papile, MD (2) · Mary Wearden, MD (2) · Richard A. Ehrenkranz, MD (2) · Sheldon B. Korones, MD (2) · Waldemar A. Carlo, MD (2) · A. Johnston, MD (1) · A. Solimano, MD (1) · Abbot R. Laptook, MD (1) · Barbara J. Stoll, MD (1)
PMID 10802492, PMID 11416871, PMID 14510322, PMID 14993550, PMID 17307536, PMID 17329511, PMID 25496504, PMID 26449871, PMID 27255954, PMID 30690595, PMID 31935746, PMID 32666584, PMID 41458086, PMID 9036320, PMID 9190553
U10HD021364 (3), U10HD021385 (3), U10HD027880 (3), U10HD034216 (3), M01RR000070 (2), M01RR000750 (2), M01RR000997 (2), M01RR001032 (2), M01RR006022 (2), M01RR008084 (2), U01HD019897 (2), U10HD021373 (2), U10HD021397 (2), U10HD021415 (2), U10HD027853 (2)