7 completed, 3 terminated, 2 recruiting, 2 withdrawn. 15 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 15 | Completed 7, Terminated 3, Recruiting 2, Withdrawn 2, Suspended 1 |
Follow Lumbar Spinal Stenosis: new trials by email Literature Review of Lumbar Spinal Stenosis trials Research Report on Lumbar Spinal Stenosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of M640 in Acute Lumbosacral Musculoskeletal Conditions. Metaxalone 640 mg Oral Tablet - Sciatica Acute, Lumbar Spinal Stenosis | Phase 4 | Recruiting | Primus Pharmaceuticals | 50 | 2023-11-15 | 2026-09-14 |
| Dexamethasone as Adjuvant to Ropivacaine in Wound Infiltration for Postoperative Analgesia Following Spinal Surgery Ropivacaine 0.75% Injectable Solution, dexamethasone 8mg - Lumbar Spinal Stenosis, Lumbar Disc Herniation | Phase 4 | Completed | University Hospital Fattouma Bourguiba | 60 | 2023-01-01 | 2023-05-23 |
| Erector Spinae Plane Block as Pain Management After Lumbar Fusion Surgery Ropivacaine Hydrochloride Injection, Sodium chloride - Spondylolisthesis, Lumbar Disc Herniation | Phase 4 | Completed | Ilse van de Wijgert | 76 | 2022-06-01 | 2024-04-17 |
| Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine, normal saline - Lumbar Spinal Stenosis, Lumbar Disc Herniation | Phase 4 | Recruiting | John O'Toole | 125 | 2022-02-01 | 2026-02-17 |
| Liposomal Bupivacaine in One-level Instrumented Posterior Spinal Fusion Liposomal bupivacaine - Lumbar Spinal Stenosis, Lumbar Disc Herniation | Phase 4 | Suspended | Allina Health System | 60 | 2019-01-26 | 2024-12-11 |
| Particulate vs. Nonparticulate Epidural Steroid Injections for Lumbar Foraminal Stenosis Kenalog Injectable Product, Decadron Phosphate, Injectable, Epidural Steroid Injection - Lumbar Spinal Stenosis | Phase 4 | Withdrawn | Hospital for Special Surgery, New York | 2017-12-01 | 2017-12-06 | |
| Effectiveness Study of the Drug Tranexamic Acid to Reduce Post-surgery Blood Loss in Spinal Surgery Tranexamic Acid, Placebo - Lumbar Spinal Stenosis, Thoracic Spinal Stenosis | Phase 4 | Completed | Massachusetts General Hospital | 29 | 2012-08-01 | 2017-06-08 |
| Study on the Treatment of Degenerative Lumbar Spine Stenosis With a Percutaneous Interspinous Implant Spacer, physiotherapy - Lumbar Spinal Stenosis | Phase 4 | Terminated | University of Cologne | 22 | 2011-03-01 | 2016-11-07 |
| MiDAS II (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study lumbar decompression - Lumbar Spinal Stenosis | Phase 4 | Completed | Vertos Medical, Inc. | 55 | 2010-02-01 | 2013-04-01 |
| Study of Epidural Steroid Injection (ESI) Versus Minimally Invasive Lumbar Decompression (Mild®) in Patients With Symptomatic Lumbar Central Canal Stenosis MILD® (Minimally Invasive Lumbar Decompression), Epidural Steroid Injection - Lumbar Spinal Stenosis | Phase 4 | Completed | Coastal Orthopedics & Sports Medicine | 38 | 2009-08-01 | 2013-11-15 |
| MiDAS I (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study Interlaminar Decompression - Lumbar Spinal Stenosis | Phase 4 | Completed | Vertos Medical, Inc. | 78 | 2008-07-01 | 2013-04-04 |
| Lumbar Stenosis Outcomes Research II opana then darvocet then placebo, opana then placebo then darvocet, placebo then opana then darvocet - Lumbar Spinal Stenosis | Phase 4 | Terminated | University of Rochester | 24 | 2008-03-01 | 2016-03-25 |
| Lumbar Stenosis Outcomes Research (LUSTOR) Pregabalin, Diphenhydramine - Lumbar Spinal Stenosis | Phase 4 | Completed | University of Rochester | 29 | 2008-03-01 | 2016-06-20 |
| Effects of X-STOP® Versus Laminectomy Study X-STOP®, Laminectomy - Lumbar Spinal Stenosis | Phase 4 | Withdrawn | Medtronic Spine LLC | 2007-11-01 | 2017-12-08 | |
| Condition of Approval Study X-STOP PEEK - Lumbar Spinal Stenosis | Phase 4 | Terminated | Medtronic Spine LLC | 176 | 2007-08-01 | 2018-01-02 |
Spinal Stenosis (15) · Intervertebral Disc Displacement (4) · Spondylolisthesis (4) · Intervertebral disc disease (2) · Radiculopathy (2) · Spondylosis (2) · Intervertebral Disc Degeneration (1) · Pain, Postoperative (1) · Spinal Diseases (1) · Synovial Cyst (1)
Bone Diseases (15) · Musculoskeletal Diseases (15) · Spinal Diseases (14) · Hernia (4) · Pathological Conditions, Anatomical (4) · Pathological Conditions, Signs and Symptoms (4) · Spondylolysis (4) · Nervous System Diseases (2) · Neuromuscular Diseases (2) · Peripheral Nervous System Diseases (2) · Spondylosis (2) · Cysts (1) · Neoplasms (1) · Neurologic Manifestations (1) · Pain (1)
Ropivacaine (2) · Acetaminophen (1) · Clonidine (1) · Dexamethasone (1) · Diphenhydramine (1) · Injections (1) · Laminectomy (1) · Metered Dose Inhalers (1) · Oxymorphone (1) · Physical Therapy Modalities (1) · Pregabalin (1) · Saline Solution (1) · Single Person (1) · Sodium Chloride (1) · Tablets (1)
Medtronic Spine LLC (2) · University of Rochester (2) · Vertos Medical, Inc. (2) · Allina Health System (1) · Coastal Orthopedics & Sports Medicine (1) · Hospital for Special Surgery, New York (1) · Ilse van de Wijgert (1) · John O'Toole (1) · Massachusetts General Hospital (1) · Primus Pharmaceuticals (1) · University Hospital Fattouma Bourguiba (1) · University of Cologne (1)
United States (11) · Germany (1) · Netherlands (1) · Tunisia (1)
Bohdan W Chopko, MD (2) · Christopher Alcala-Marquez, MD (1) · David Caraway, MD (1) · David L Caraway, MD, PhD (1) · Jim Malcolm, MD (1) · John D Markman, M.D (1) · John D Markman, M.D. (1) · John O'Toole, MD (1) · Kirkham B Wood, MD (1) · Lora Brown, MD (1) · S Sodhi (1) · Thomas Kaulhausen, MD (1) · Volker Sonntag, MD (1)