94 completed, 40 unknown, 25 recruiting, 13 not yet recruiting. 99 Not applicable, 15 Phase 4, 5 Phase 2, 4 Phase 3, 3 Early Phase 1.
Follow Lumbar Spinal Stenosis: new trials by email Literature Review of Lumbar Spinal Stenosis trials Research Report on Lumbar Spinal Stenosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Continuous Erector Spinae Block for Analgesia Following Lumbar Decompression Continuous erector spinae plane block - Lumbar Spinal Stenosis, Lumbar Radiculopathy | Not applicable | Not yet recruiting | Nova Scotia Health Authority | 100 | 2026-12-01 | 2026-02-17 |
| Kore Fiber PLF Study Kore Fiber, Autologous bone graft - Degenerative Lumbar Spine Diseases, Lumbar Degenerative Disc Disease | Not applicable | Not yet recruiting | Kolosis Bio, LLC | 75 | 2026-11-01 | 2026-10-22 |
| Surgical Treatment of Adjacent Segment Stenosis Microsurgical Decompression with Extension of Fusion, Microsurgical Decompression Alone - Adjacent Segment Disease, Lumbar Spinal Stenosis | Not applicable | Recruiting | Charite University, Berlin, Germany | 338 | 2026-10-27 | 2026-10-28 |
| CLE-PAD : Prevalence of PAD in Patients With Surgically Lumbar Spinal Stenosis contrast-enhanced CT scan - PAD - Peripheral Arterial Disease, Lumbar Spinal Stenosis | Not applicable | Recruiting | Rennes University Hospital | 49 | 2026-08-01 | 2026-08-12 |
| Role of Intraoperative Computed Tomography in Assessment of Spine Instability in Lumbar Degenerative Disease Intraoperative Computed Tomography (O-arm) - Degenerative Lumbar Spine Diseases, Lumbar Spinal Instability | Not yet recruiting | 4th Military Clinical Hospital with Polyclinic, Poland | 100 | 2026-08-01 | 2026-06-12 | |
| Hybrid vs Fluoroscopy-Guided Interlaminar Epidural Injection in Lumbar Spinal Stenosis Ultrasound-guided lumbar interlaminar epidural steroid injection with fluoroscopic confirmation, Fluoroscopy-guided lumbar interlaminar epidural steroid injection - Lumbar Spinal Stenosis | Not applicable | Not yet recruiting | Marmara University | 44 | 2026-07-01 | 2026-05-29 |
| Effect of Obesity Phenotype on Intraabdominal Pressure and Bleeding in Major Lumbar Spinal Surgery Intraabdominal Pressure Measurement via Urinary Bladder Catheter, Total Intravenous Anesthesia (TIVA) - Lumbar Spinal Stenosis, Lumbar Degenerative Disease | Not yet recruiting | Marmara University Pendik Training and Research Hospital | 90 | 2026-06-15 | 2026-07-07 | |
| Comparative Analysis of Two Transforaminal Lumbar Interbody Fusion (TLIF) Procedures in the Treatment of Single-Level Lumbar Spinal Stenosis (LSS): A Single-Center, Prospective, Randomized Controlled Trial LUSE-TLIF, MIS-TLIF - Lumbar Spinal Stenosis | Not applicable | Recruiting | The Third Affiliated Hospital of Southern Medical University | 276 | 2026-03-18 | 2026-05-14 |
| Effect of Irrigation Pressure on Postoperative Complications and Surgical Field Clarity in Unilateral Biportal Endoscopic Surgery Unilateral Biportal Endoscopic Surgery - Lumbar Disc Herniation, Lumbar Spinal Stenosis | Not applicable | Recruiting | Fan Zhang | 80 | 2026-02-05 | 2026-09-23 |
| Gait and Paraspinal sEMG in Degenerative Spinal Diseases Gait analysis and surface electromyography analysis - Adult Spinal Deformity, Degenerative Scoliosis | Not yet recruiting | Xuanwu Hospital, Beijing | 120 | 2025-12-10 | 2025-12-30 | |
| Opioid Free and Opioid Based Anesthesia in Elective Lumbar Spine Surgery Opioid-free Anesthesia, Erector Spinae Plane Block, Opioid based Anesthesia - Lumbar Spinal Stenosis, Lumbar Disc Herniation With Radiculopathy | Recruiting | Marmara University | 75 | 2025-12-09 | 2026-03-23 | |
| Presence of Dural Pulsation in Patients Diagnosed With Lumbar Spinal Stenosis Lumbar Spinal Stenosis, Numerical Rating Scale | Recruiting | Marmara University | 100 | 2025-12-07 | 2026-03-11 | |
| Decompressive Laminectomy Versus Laminectomy With Transpedicular Fixation in Lumbar Spinal Stenosis Decompressive Laminectomy, Decompressive Laminectomy With Transpedicular Screw Fixation - Lumbar Spinal Stenosis | Early Phase 1 | Recruiting | Punjab Health Care Commission | 60 | 2025-10-01 | 2025-12-15 |
| Artificial Intelligence (AI)-Based Prediction of Treatment Response in Sciatica Patients Receiving Transforaminal Epidural Steroid Injection Sciatica, Low Back Pain | Not yet recruiting | Marmara University | 1500 | 2025-07-01 | 2025-07-23 | |
| Lumbar Spinal Stenosis and Central Sensitization Lumbar Spinal Stenosis | Completed | Karabuk University | 81 | 2025-06-17 | 2026-04-22 | |
| A Study on the Clinical Use of a New Expandable OLIF Cage With Posterior Bone Grafting in Lumbar Spine Surgery Expandable OLIF cage with posterior bone grafting, Conventional OLIF cage - Lumbar Spondylolisthesis, Degenerative Lumbar Scoliosis | Not applicable | Not yet recruiting | The Affiliated Hospital of Qingdao University | 340 | 2025-06-10 | 2025-06-19 |
| The Effect of Oxytocin Nasal Spray on Preventing Postoperative Delirium in Elderly Patients Undergoing Orthopedic Surgery oxytocin nasal spray - Cervical Spinal Stenosis, Thoracic Spinal Stenosis | Phase 2 | Completed | Zhejiang University | 227 | 2025-06-01 | 2026-08-20 |
| Radiological Lumbar Spinal Stenosis Level and Patient Questionnaires Lumbar Spinal Stenosis, Low Back Pain | Completed | Sisli Hamidiye Etfal Training and Research Hospital | 120 | 2025-06-01 | 2025-11-19 | |
| 124I-Evuzamitide PET/CT Imaging In Patients With Lumbar Spinal Stenosis and Carpal Tunnel Syndrome 124I-evuzamitide - Lumbar Spinal Stenosis, Carpal Tunnel Syndrome (CTS) | Phase 2 | Enrolling by invitation | University of Tennessee Graduate School of Medicine | 40 | 2025-05-22 | 2026-07-21 |
| Frailty and Associated Factors in Lumbar Spinal Stenosis Lumbar Spinal Stenosis | Completed | Karabuk University | 91 | 2025-05-02 | 2026-04-22 |
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Spinal Stenosis (202) · Spondylolisthesis (30) · Intervertebral Disc Displacement (29) · Radiculopathy (16) · Intervertebral Disc Degeneration (13) · Low Back Pain (13) · Intervertebral disc disease (7) · Motor Activity (6) · Spinal Diseases (6) · Pain, Postoperative (5) · Spondylosis (5) · Back Pain (4) · Chronic Pain (3) · Constriction, Pathologic (3) · Intermittent Claudication (3)
Bone Diseases (202) · Musculoskeletal Diseases (202) · Spinal Diseases (196) · Pathological Conditions, Signs and Symptoms (59) · Signs and Symptoms (37) · Pathological Conditions, Anatomical (33) · Neurologic Manifestations (31) · Spondylolysis (30) · Hernia (29) · Pain (27) · Spondylosis (27) · Nervous System Diseases (24) · Neuromuscular Diseases (22) · Peripheral Nervous System Diseases (21) · Back Pain (15)
Decompression (5) · Laminectomy (5) · Surgical Procedures, Operative (5) · Acetaminophen (4) · Gene Fusion (4) · Physical Therapy Modalities (4) · Acupuncture Therapy (3) · Injections (3) · Surveys and Questionnaires (3) · Control Groups (2) · Cupping Therapy (2) · Dexamethasone (2) · Electroacupuncture (2) · Exercise (2) · Gabapentin (2)
Peking University Third Hospital (8) · Marmara University (5) · Assiut University (4) · Boston Scientific Corporation (4) · Vertos Medical, Inc. (4) · Jaseng Medical Foundation (3) · Karabuk University (3) · Medtronic Spine LLC (3) · Premia Spine (3) · University Hospital, Basel, Switzerland (3) · Université du Québec à Trois-Rivières (3) · VA Office of Research and Development (3) · Xuanwu Hospital, Beijing (3) · Assistance Publique - Hôpitaux de Paris (2) · Baxano Surgical, Inc. (2)
United States (62) · China (21) · Turkey (Türkiye) (19) · South Korea (10) · Canada (8) · France (7) · Denmark (6) · Switzerland (6) · Netherlands (4) · Russia (4) · Spain (4) · Czechia (3) · Egypt (3) · Germany (3) · Italy (3)
Natalie Bloom Lyons (3) · Bohdan W Chopko, MD (2) · Cordula Netzer, PD Dr. med. (2) · Debra K. Weiner, MD (2) · Nicolai Maldaner, MD (2) · Oliver B Zielinski, MD (2) · Alberto Gotfryd, PhD (1) · Alessandro Gasbarrini, MD (1) · Alfredo Conti, Prof. (1) · Andrey Grin, MD, PhD (1) · Angela M Carrascosa-Granada, M.D.,M.Sc.,Ph.D. (1) · Annegret Muendermann, Prof. Dr. MD (1)
PMID 39313282, PMID 10976589, PMID 16231283, PMID 19219713, PMID 20047458, PMID 20648206, PMID 20664045, PMID 21309472, PMID 21429671, PMID 21728727, PMID 21802441, PMID 21859765, PMID 22215593, PMID 22272730, PMID 22922544, PMID 23575742, PMID 23992774, PMID 24228747, PMID 24716251, PMID 24996648, PMID 25575084, PMID 25608246, PMID 25705958, PMID 25760812, PMID 26076437, PMID 26507388, PMID 26824399, PMID 27074066, PMID 27074067, PMID 27107209, PMID 27501016, PMID 28087128, PMID 28289281, PMID 28327114, PMID 28362963, PMID 28467893, PMID 28586471, PMID 28629540, PMID 28930284, PMID 28965836, PMID 29048602, PMID 29372860, PMID 29499383, PMID 30173327, PMID 30227869, PMID 30573489, PMID 30646197, PMID 30703349, PMID 31042663, PMID 31233803
2019 (1), R01AG081582 (1), R01AT012534 (1)