9 completed, 4 terminated, 1 active not recruiting, 1 suspended. 5 Phase 3, 3 Phase 1, 2 Not applicable, 2 Phase 2, 2 Phase 4.
Follow Oxymorphone: new trials by email Literature Review of Oxymorphone trials Research Report on Oxymorphone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure Carbidopa-Levodopa 25 Mg-100 Mg Oral Tablet, Naproxen 500 Mg, Opioids - Opioid Use, Opioid Dependence | Phase 2 | Active not recruiting | Northwestern University | 60 | 2021-01-01 | 2024-11-27 |
| Levorphanol as a Second Line Opioid in Reducing Pain in Patients With Cancer Hydrocodone, Hydromorphone, Levorphanol - Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm | Early Phase 1 | Terminated | M.D. Anderson Cancer Center | 43 | 2018-11-29 | 2025-08-03 |
| A Study to Evaluate the Abuse Potential of Oxymorphone Compared to Other Mu Opioid Agonists. Intravenous Challenge Drug - Opioid Use Disorder | Phase 2 | Completed | New York State Psychiatric Institute | 16 | 2018-03-15 | 2023-09-07 |
| Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis Automated recommendation at the start of the case, Automated notification at the start of surgery, Preoperative recommendations: by email - Postoperative Nausea and Vomiting | Not applicable | Completed | Vanderbilt University | 27034 | 2016-07-01 | 2019-03-07 |
| Clinical Study to Evaluate the Effectiveness, Safety, and Tolerability of Oxymorphone Immediate Release (IR) Oral Liquid in Post Surgical Pediatric Subjects Oxymorphone HCl, Placebo - Post-Operative Pain, Acute Pain | Phase 3 | Terminated | Endo USA Inc., a Keenova Therapeutics Company | 28 | 2016-04-01 | 2021-10-26 |
| Safety, Tolerability, Effectiveness, and Pharmacokinetic Data in Opioid-experienced Children Oxymorphone hydrochloride (HCl) - Chronic Pain, Postsurgical Pain | Phase 3 | Suspended | Endo USA Inc., a Keenova Therapeutics Company | 15 | 2013-03-11 | 2020-12-23 |
| Effectiveness, Safety, and Tolerability Study of Oxymorphone Immediate Release (IR) Oral Liquid in Post Surgical Pediatric Subjects oxymorphone HCl - Post Operative Pain | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 61 | 2010-12-13 | 2021-08-20 |
| Study to Compare Oxymorphone Extended-Release (Opana ER) Versus Oxycodone Controlled-Release (Oxycontin) Oxymorphone ER, Oxycodone CR, Placebo - Healthy | Phase 4 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 78 | 2009-06-01 | 2017-10-05 |
| Open-Label Safety and Tolerability of Oxymorphone IR and ER in Opioid Tolerant Pediatric Subjects Oxymorphone ER - Chronic Pain | Phase 3 | Terminated | Endo USA Inc., a Keenova Therapeutics Company | 27 | 2008-11-17 | 2020-12-16 |
| Bioequivalency Study of Oxymorphone Hydrochloride 10 mg Tablets Under Fasted Conditions Oxymorphone - Pain | Phase 1 | Completed | Roxane Laboratories | 42 | 2008-06-01 | 2018-01-23 |
| Lumbar Stenosis Outcomes Research II opana then darvocet then placebo, opana then placebo then darvocet, placebo then opana then darvocet - Lumbar Spinal Stenosis | Phase 4 | Terminated | University of Rochester | 24 | 2008-03-01 | 2016-03-25 |
| Bioavailability of Oxymorphone Hydrochloride 40 mg Extended Release Tablets Under Fed Conditions oxymorphone hydrochloride, Opana - Pain | Phase 1 | Completed | Sandoz | 32 | 2007-11-01 | 2017-03-29 |
| Bioavailability of Oxymorphone Hydrochloride 40 mg Extended Release Tablets Under Fasted Conditions oxymorphone, Oxymorphone - Pain | Phase 1 | Completed | Sandoz | 50 | 2007-11-01 | 2017-03-29 |
| A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation) Oxymorphone - Pain | Not applicable | Completed | Icahn School of Medicine at Mount Sinai | 12 | 2007-11-01 | 2016-02-03 |
| Efficacy and Safety of Oxymorphone Immediate Release in Post-surgical Acute Pain Oxymorphone immediate release - Acute Pain | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 320 | 2004-09-01 | 2024-01-02 |
Pain (6) · Chronic Pain (4) · Acute Pain (3) · Pain, Postoperative (3) · Back Pain (2) · Opioid-Related Disorders (2) · Arthritis (1) · Arthritis, Rheumatoid (1) · Back Injuries (1) · Complex Regional Pain Syndromes (1) · Contracture (1) · Diabetes Mellitus (1) · Diabetic Neuropathies (1) · Fibromyalgia (1) · Fractures, Bone (1)
Endo USA Inc., a Keenova Therapeutics Company (6) · Sandoz (2) · Icahn School of Medicine at Mount Sinai (1) · M.D. Anderson Cancer Center (1) · New York State Psychiatric Institute (1) · Northwestern University (1) · Roxane Laboratories (1) · University of Rochester (1) · Vanderbilt University (1)
United States (12) · Canada (1)
Daryl G. Ficklin, D.O. (2) · Akhila S Reddy (1) · Apkar V Apkarian, PhD (1) · John D Markman, M.D. (1) · Jonathan P Wanderer, MD, MPhil (1) · Marco Pappagallo, MD (1) · Saji Vijayan (1) · Saji Vijayan, MD (1) · Sandra D Comer, PhD (1) · Shannon Dalton (1) · Soran Hong, MD (1)