20 withdrawn. 20 Phase 2, 5 Phase 1, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 20 | Withdrawn 20 |
| Phase 1 | 5 | Withdrawn 5 |
| Phase 3 | 3 | Withdrawn 3 |
Follow Ischemic Stroke: new trials by email Literature Review of Ischemic Stroke trials Research Report on Ischemic Stroke
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Glenzocimab in Anterior Stroke With Large Ischemic Core Eligible for Endovascular Therapy glenzocimab, placebo - Acute Ischemic Stroke | Phase 2 / Phase 3 | Withdrawn | Fondation Ophtalmologique Adolphe de Rothschild | 2026-09-01 | 2026-09-09 | |
| Minocycline Efficacy in Improving Neurological Outcome of Patients Who Undergo Endovascular Revascularization for Acute Ischemic Stroke Minocyclin - Acute Ischemic Stroke | Phase 2 | Withdrawn | State University of New York at Buffalo | 2025-12-01 | 2026-03-06 | |
| A Study to Evaluate the Efficacy and Safety of BIIB131 for Participants With Ischemic Stroke Between 4.5 and 24 Hours After Last Known Well BIIB131, Placebo - Ischemic Stroke | Phase 2 | Withdrawn | Biogen | 2024-03-29 | 2024-02-12 | |
| PLAsticity, Security and Tolerance to Intermittent Hypoxic Conditioning Following Stroke Hypoxia, intermittent, Normoxia - Stroke, Ischemic, Stroke Sequelae | Phase 1 / Phase 2 | Withdrawn | University Hospital, Grenoble | 2024-01-01 | 2024-06-04 | |
| Safety and Efficacy of ALZT-OP1a as Adjuvant Treatment in Subjects With Post-Ischemic Stroke Cognitive Impairment (PSCI) Cromolyn, Placebo - Ischemic Stroke, Post-stroke Cognitive Impairment | Phase 2 | Withdrawn | AZTherapies, Inc. | 2023-12-01 | 2022-03-03 | |
| Endovascular Stroke Treatment And Reteplase Protocol Reteplase Injection - Ischemic Stroke | Phase 2 | Withdrawn | Zeenat Qureshi Stroke Institute | 2023-07-01 | 2024-04-09 | |
| Pilot Study of Ketamine Sedation for Aneurysmal Subarachnoid Hemorrhage Ketamine Hydrochloride, Propofol - Subarachnoid Hemorrhage, Aneurysmal | Phase 2 / Phase 3 | Withdrawn | Jenna L Leclerc MD, PhD | 2023-04-27 | 2023-05-01 | |
| Clinical Trial to Evaluate the Safety of Continuous IV Tirofiban in Acute Ischemic Stroke Tirofiban Hydrochloride, Placebo - Acute Ischemic Stroke, Ischemic Stroke | Phase 1 / Phase 2 | Withdrawn | University of Iowa | 2023-03-01 | 2022-09-21 | |
| OsciPulse D-dimer Efficacy Trial OsciPulse system, Flowtron ACS900 - Venous Thromboses, Ischemic Stroke | Phase 2 | Withdrawn | OsciFlex LLC | 2022-12-01 | 2023-11-07 | |
| A Study to Assess the Efficacy, Safety, and Pharmacokinetics of TB006 in Participants With Acute Ischemic Stroke TB006, Placebo - Acute Ischemic Stroke | Phase 2 | Withdrawn | TrueBinding, Inc. | 2022-07-26 | 2024-01-12 | |
| Study to Evaluate The Safety and Efficacy of Balovaptan in Participants With Acute Ischemic Stroke at a High Risk of Developing Malignant Brain Edema Balovaptan, Placebo - Acute Ischemic Stroke | Phase 2 | Withdrawn | Hoffmann-La Roche | 2022-06-22 | 2023-08-07 | |
| Sphenopalatine Ganglion Block for the Treatment of Post-Stroke Headache Liquid Lidocaine, Placebo - Headache, Stroke | Phase 2 | Withdrawn | University of Utah | 2022-03-23 | 2024-11-13 | |
| Combination of the Immune Modulator Dimethyl Fumarate With Intraarterial Treatment in Acute Ischemic Stroke Dimethyl Fumarate, Placebo - Acute Ischemic Stroke | Phase 2 | Withdrawn | Xuanwu Hospital, Beijing | 2021-06-01 | 2023-10-25 | |
| Dose-finding Study of Selective Serotonin Reuptake Inhibitors to Enhance Neuroplasticity Administration of SSRI escitalopram, Paired Associative stimulation, Administration of Placebo - Stroke, Ischemic | Phase 1 / Phase 2 | Withdrawn | Burke Medical Research Institute | 2020-03-11 | 2021-07-23 | |
| Mesenchymal Stromal Cells for Ischemic Stroke MSC Infusion, Placebo Comparator - Ischemic Stroke | Phase 1 / Phase 2 | Withdrawn | Sean Savitz | 2016-12-01 | 2018-04-18 | |
| Combinating Fingolimod With Alteplase Bridging With Mechanical Thrombectomy in Acute Ischemic Stroke Fingolimod - Stroke, Inflammation | Phase 2 | Withdrawn | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2016-11-01 | 2021-07-22 | |
| REperfusion With Cooling in CerebraL Acute IscheMia II Normothermia, Mild hypothermia, Trevo Pro Retriever (Stryker Corp.) - Ischemic Stroke, Hypothermia | Phase 2 | Withdrawn | WellStar Health System | 2016-02-01 | 2016-02-17 | |
| Safety of Escalating Doses of Intravenous Bone Marrow-Derived Mesenchymal Stem Cells in Patients With a New Ischemic Stroke bone marrow-derived mesenchymal stem cells, Placebo - Ischemic Stroke | Phase 1 / Phase 2 | Withdrawn | University of California, Irvine | 2016-01-01 | 2016-01-22 | |
| Tenecteplase Versus Alteplase in Ischemic Stroke Management (TALISMAN) Tenecteplase, Alteplase - Ischemic Stroke | Phase 2 / Phase 3 | Withdrawn | Reza Behrouz, DO | 2015-01-01 | 2015-09-23 | |
| Asia Africa Streptokinase Trial Streptokinase - Ischemic Stroke | Phase 2 | Withdrawn | University of Alberta | 2014-06-01 | 2022-05-27 |
Stroke (6) · Ischemia (3) · Cerebral Infarction (2) · Bites and Stings (1) · Body Temperature Changes (1) · Brain Diseases (1) · Brain Infarction (1) · Brain Ischemia (1) · Cardiovascular Diseases (1) · Central Nervous System Diseases (1) · Cerebrovascular Disorders (1) · Headache (1) · Hypothermia (1) · Inflammation (1)
Brain Diseases (19) · Cardiovascular Diseases (19) · Central Nervous System Diseases (19) · Cerebrovascular Disorders (19) · Nervous System Diseases (19) · Vascular Diseases (19) · Stroke (14) · Pathological Conditions, Signs and Symptoms (7) · Pathologic Processes (5) · Infarction (2) · Necrosis (2) · Brain Infarction (1) · Brain Ischemia (1) · Chemically-Induced Disorders (1) · Embolism and Thrombosis (1)
Cromolyn Sodium (1) · Dimethyl Fumarate (1) · Fingolimod Hydrochloride (1) · Hypothermia, Induced (1) · Ketamine (1) · Minocycline (1) · Propofol (1) · Reperfusion (1) · Sodium Chloride (1) · Streptokinase (1) · TB006 (1) · Tenecteplase (1) · Tirofiban (1) · Tissue Plasminogen Activator (1) · balovaptan (1)
AZTherapies, Inc. (1) · Biogen (1) · Burke Medical Research Institute (1) · Fondation Ophtalmologique Adolphe de Rothschild (1) · Hoffmann-La Roche (1) · Jenna L Leclerc MD, PhD (1) · OsciFlex LLC (1) · Reza Behrouz, DO (1) · Sean Savitz (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · State University of New York at Buffalo (1) · TrueBinding, Inc. (1) · University Hospital, Grenoble (1) · University of Alberta (1) · University of California, Irvine (1)
United States (8) · China (1) · France (1)
Adam H de Havenon, MD (1) · Adnan H Siddiqui, MD PhD (1) · Ashfaq Shuaib, MD, FRCPC (1) · David A. Brazier, BS (1) · Jenna L Leclerc, MD, PhD (1) · Min Lou, MD,PhD (1) · Reza Behrouz, DO (1) · Rishi Gupta, MD (1) · Sean Savitz, MD (1) · Steve Cramer, MD (1) · Tomoko Kitago, MD (1)
PMID 24127913, PMID 25338927, PMID 26387127, PMID 26926875, PMID 29285576, PMID 30054011, PMID 30152015, PMID 30877613, PMID 31694924, PMID 32583883, PMID 8656545