2 completed, 2 withdrawn, 1 active not recruiting, 1 available. 4 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Active not recruiting 1, Completed 1, Terminated 1, Withdrawn 1 |
| Phase 1 | 3 | Completed 2, Withdrawn 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 2a Multicenter Clinical Trial of TB006 in Participants With Parkinson's Disease TB006, Placebo - Parkinson's Disease (PD) | Phase 2 | Active not recruiting | TrueBinding, Inc. | 62 | 2025-03-20 | 2026-04-23 |
| A Long Term Extension Study to Assess the Safety of TB006 in Participants With Alzheimer's Disease TB006 - Alzheimer's Disease | Phase 2 | Terminated | TrueBinding, Inc. | 119 | 2022-09-15 | 2026-05-06 |
| A Study to Assess the Efficacy, Safety, and Pharmacokinetics of TB006 in Participants With Acute Ischemic Stroke TB006, Placebo - Acute Ischemic Stroke | Phase 2 | Withdrawn | TrueBinding, Inc. | 2022-07-26 | 2024-01-12 | |
| Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of TB006 in Participants With Alzheimer's Disease TB006, Placebo - Alzheimer's Disease | Phase 1 / Phase 2 | Completed | TrueBinding, Inc. | 154 | 2021-10-08 | 2023-11-18 |
| Sequential Dose-escalation Study to Assess the Safety, Tolerability and Pharmacokinetics of TB006 in Healthy Subjects TB006, Sterile saline (Placebo) - Alzheimer Disease | Phase 1 | Completed | TrueBinding, Inc. | 48 | 2021-06-01 | 2024-12-09 |
| Study of TB006 in Outpatient Patients With Mild to Moderate COVID-19 TB006, Placebo - Covid19 | Phase 1 | Withdrawn | TrueBinding, Inc. | 2021-06-01 | 2022-05-18 | |
| TB006 Expanded Access (EA) Compassionate Use TB006 - Alzheimer Disease | Available | TrueBinding, Inc. | 2024-12-09 |
Alzheimer Disease (4) · COVID-19 (1) · Ischemia (1) · Ischemic Stroke (1) · Parkinson Disease (1) · Stroke (1)
TB006 (7)
United States (4)
Alan K Jacobs, MD (1) · David Walling, MD (1) · George Haig, PharmD (1)