25 unknown, 22 completed, 21 recruiting, 13 not yet recruiting. 26 Not applicable, 19 Phase 3, 13 Phase 2, 13 Phase 4, 1 Phase 1.
Follow Ischemic Stroke, Acute: new trials by email Literature Review of Ischemic Stroke, Acute trials Research Report on Ischemic Stroke, Acute
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lumbrokinase vs Placebo in Moderate-to-Severe Ischemic Stroke Lumbrokinase, Lumbrokinase Placebo - Ischemic Stroke, Acute | Phase 4 | Not yet recruiting | Xinqiao Hospital of Chongqing | 1196 | 2026-11-01 | 2026-08-13 |
| Tirofiban Combined With Aspirin in Moderate Ischemic Stroke Tirofiban, Tirofiban-matching placebo - Ischemic Stroke, Acute | Phase 4 | Not yet recruiting | Xinqiao Hospital of Chongqing | 1168 | 2026-10-01 | 2026-08-12 |
| Continuous Blood Pressure Variability and Small Vessel Disease in Acute Ischemic Stroke Cuffless ring-type continuous blood pressure monitor - Ischemic Stroke, Acute, Blood Pressure Variability | Not yet recruiting | Minyoul Baik | 450 | 2026-10-01 | 2026-10-29 | |
| Intra-arterial Thrombolysis For Acute Ischemic Stroke With Medium Vessel Occlusion Recombinant Tissue Plasminogen Activator (rt-PA), Intra-arterial Thrombolysis, Best Medical Management - Medium Vessel Occlusion, Ischemic Stroke, Acute | Phase 3 | Recruiting | The First Affiliated Hospital with Nanjing Medical University | 372 | 2026-09-19 | 2026-09-23 |
| Artificial Intelligence Support for Stroke AI-assisted thrombolysis decision support - Ischemic Stroke, Acute | Not applicable | Recruiting | Capital Medical University | 516 | 2026-08-26 | 2026-08-27 |
| A Trial of Adacolumn on Cerebral Edema After Anterior Circulation Ischemic Stroke Adacolumn®, Standard Reperfusion Therapy, Standard Medical Management - Cerebral Edema, Ischemic Stroke, Acute | Not applicable | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 10 | 2026-08-10 | 2026-08-07 |
| Clinical Efficacy and Mechanism Research of Getong Tongluo Capsule in Ischemic Stroke Getong Tongluo Capsule, Matched Starch Placebo Capsule, Standard Routine Therapy for Ischemic Stroke - Ischemic Stroke, Acute | Not applicable | Not yet recruiting | Nanfang Hospital, Southern Medical University | 216 | 2026-08-01 | 2026-07-08 |
| TeleStroke-Guided Thrombolysis for Acute Ischemic Stroke in Oman alteplase or tenecteplase - Ischemic Stroke, Acute, Ischemic Stroke | Phase 4 | Not yet recruiting | Oman Ministry of Health | 200 | 2026-08-01 | 2026-07-22 |
| MyStroke for Stroke Survivors and Caregivers MyStroke - Stroke, Acute, Ischemic Stroke, Acute | Not applicable | Not yet recruiting | University of Pennsylvania | 690 | 2026-08-01 | 2026-07-31 |
| A Trial of Edaravone Dexborneol in Acute Ischemic Stroke With Active Malignancy edaravone dexborneol injection, Standard therapeutic protocol - Ischemic Stroke, Acute, Active Malignancies | Phase 4 | Not yet recruiting | Nanfang Hospital, Southern Medical University | 144 | 2026-08-01 | 2026-04-16 |
| Benson Relaxation for Anxiety, Depression, and Insomnia After Stroke Benson Relaxation Technique, Structured Health Education - Ischemic Stroke, Acute, Post-stroke Anxiety | Not applicable | Completed | Changchun University of Traditional Chinese Medicine | 84 | 2026-07-28 | 2026-09-29 |
| Single Bolus Non-immunogenic Staphylokinase in Patients With Acute Ischemic Stroke Within 4.5-24 Hours of Symptom Onset non-immunogenic staphylokinase, Placebo - Ischemic Stroke, Acute | Phase 3 | Recruiting | Supergene, LLC | 990 | 2026-06-09 | 2026-10-01 |
| Safety and Efficacy of Remote Ischemic Conditioning in Patients With Acute Myocardial Injury Following Acute Ischemic Stroke Remote Ischemic Conditioning, Sham Remote Ischemic Conditioning - Ischemic Stroke, Acute, Myocardial Injury | Phase 3 | Not yet recruiting | Capital Medical University | 580 | 2026-05-01 | 2026-04-15 |
| Tegoprazan for Prevention of Gastrointestinal Complication in Ischemic Stroke Patients on Antiplatelet Therapy (TegoStroke) Tegoprazan 50 mg, Placebo - Ischemic Stroke, Ischemic Stroke, Acute | Phase 3 | Recruiting | Hanyang University Guri Hospital | 1524 | 2026-01-26 | 2026-07-08 |
| Predictors of Post-Thrombectomy Cognitive Impairment in Acute Ischemic Stroke Patients Ischemic Stroke, Acute | Not yet recruiting | Assiut University | 120 | 2025-12-01 | 2025-11-19 | |
| Expansion-floating Craniotomy for the Treatment of Malignant Cerebral Edema Caused by Acute Ischemic Stroke Expansion-floating Craniotomy, decompressive craniectomy, drug conservative therapeutic - Ischemic Stroke, Acute, Malignant Cerebral Edema | Not yet recruiting | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | 356 | 2025-10-01 | 2025-09-29 | |
| Methylprednisolone Sodium Succinate With Endovascular ThRombectomy for Large Ischemic STroke Methylprednisolone sodium succinate, Placebo - Ischemic Stroke, Acute | Not applicable | Not yet recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 912 | 2025-10-01 | 2025-09-16 |
| Human Induced Neural Stem Cell-derived Exosomes for Treating Acute Ischemic Stroke iNSC-EV01, Placebo - Ischemic Stroke, Acute | Phase 1 / Phase 2 | Not yet recruiting | Xuanwu Hospital, Beijing | 38 | 2025-10-01 | 2025-08-27 |
| Effects of Transcranial Magnetic Stimulation After Endovascular Treatment for Acute Ischemic Stroke Transcranial Magnetic Stimulation Active, Transcranial Magnetic Stimulation Sham - Ischemic Stroke, Acute, Endovascular Thrombectomy | Not applicable | Recruiting | Xijing Hospital | 60 | 2025-08-02 | 2025-12-04 |
| Cerebrolysin in Early Stroke Rehabilitation - Tertiary Study Cerebrolysin treatment, Standard treatment (including neurorehabilitation) of acute ischemic stroke - Ischemic Stroke, Acute, Rehabilitation Outcome | Not applicable | Recruiting | University Medical Centre Ljubljana | 30 | 2025-06-13 | 2025-07-09 |
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Ischemic Stroke (83) · Stroke (18) · Brain Diseases (3) · Cerebrovascular Disorders (3) · cyclopia sequence (3) · Brain Edema (2) · Cerebral Infarction (2) · Infarction, Middle Cerebral Artery (2) · Vertebrobasilar Insufficiency (2) · Anxiety Disorders (1) · Atrial Fibrillation (1) · Brain Infarction (1) · Brain Injuries, Traumatic (1) · Central Nervous System Diseases (1) · Cerebral Small Vessel Diseases (1)
Cardiovascular Diseases (83) · Nervous System Diseases (83) · Vascular Diseases (83) · Central Nervous System Diseases (82) · Brain Diseases (80) · Cerebrovascular Disorders (80) · Stroke (65) · Pathologic Processes (10) · Pathological Conditions, Signs and Symptoms (10) · Brain Ischemia (8) · Infarction (5) · Ischemia (5) · Necrosis (5) · Brain Infarction (4) · Intracranial Arterial Diseases (3)
Tenecteplase (6) · Aspirin (3) · Minocycline (3) · Tirofiban (3) · Physical Therapy Modalities (2) · Tissue Plasminogen Activator (2) · 3-n-butylphthalide (1) · Clopidogrel (1) · Decompressive Craniectomy (1) · Deferoxamine (1) · Injections (1) · Left Atrial Appendage Closure (1) · MAX protein, human (1) · Methylprednisolone (1) · Methylprednisolone Hemisuccinate (1)
Beijing Tiantan Hospital (12) · Nanfang Hospital, Southern Medical University (5) · Can Tho Stroke International Services Hospital (4) · Capital Medical University (4) · Dongzhimen Hospital, Beijing (3) · Xijing Hospital (3) · Hospital Universitari Vall d'Hebron Research Institute (2) · Xinqiao Hospital of Chongqing (2) · Ying Gao (2) · Afyonkarahisar Health Sciences University (1) · Assiut University (1) · Central Hospital, Nancy, France (1) · Changchun University of Traditional Chinese Medicine (1) · Chonbuk National University Hospital (1) · Daping Hospital and the Research Institute of Surgery of the Third Military Medical University (1)
China (37) · United States (5) · Vietnam (5) · Russia (4) · Germany (3) · South Korea (3) · Spain (3) · Australia (2) · France (2) · Brazil (1) · Canada (1) · Egypt (1) · Indonesia (1) · Mexico (1) · New Zealand (1)
Yongjun Wang (3) · Cuong Tran Chi, Doctor (2) · Yongjun Wang, MD, PhD (2) · Zhongming Qiu (2) · Arunodaya R Gujjar, MD, DM, FRCP (1) · Bruce Campbell, MD, PhD (1) · Chan-Hyuk Lee, Dr. (1) · Christopher G Favilla, MD (1) · Chuanzhi Duan, MD (1) · Craig Anderson, PhD (1) · Cuong C Tran, Doctor (1) · Cuong C Tran, PhD (1) · Dhanunjaya Lakkireddy, MD (1)
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2019 (1), U01NS131797 (1)