22 completed, 5 terminated, 3 not yet recruiting, 3 unknown. 36 Phase 3, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 36 | Completed 22, Terminated 5, Not yet recruiting 3, Unknown 3, Recruiting 2, Active not recruiting 1 |
| Phase 2 | 7 | Completed 4, Recruiting 1, Terminated 1, Unknown 1 |
Follow Ischemic Attack, Transient: new trials by email Literature Review of Ischemic Attack, Transient trials Research Report on Ischemic Attack, Transient
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Upfront Lipid-Lowering Therapy With Statins Combined With Hybutimibe in Patients With Acute Ischemic Stroke or Transient Ischemic Attack. Atorvastatin, Hybutimibe 10mg QD - Ischemia Stroke, TIA (Transient Ischemic Attack) | Phase 3 | Not yet recruiting | First Affiliated Hospital of Wannan Medical College | 520 | 2026-11-30 | 2026-11-04 |
| Zastaprazan for the prEvention of Upper GI Bleeding in Ischemic Stroke Zastaprazan, Placebo - Ischemic Stroke, Transient Ischemic Attack | Phase 3 | Not yet recruiting | Asan Medical Center | 984 | 2026-10-15 | 2026-10-09 |
| Cilostazol for Prevention of Recurrent Stroke Trial Cilostazol 100 mg Tablets, Placebo - Stroke Recurrence, Myocardial Infarction | Phase 3 | Not yet recruiting | Stanford University | 2000 | 2026-10-01 | 2026-10-26 |
| Tegoprazan for Prevention of Gastrointestinal Complication in Ischemic Stroke Patients on Antiplatelet Therapy (TegoStroke) Tegoprazan 50 mg, Placebo - Ischemic Stroke, Ischemic Stroke, Acute | Phase 3 | Recruiting | Hanyang University Guri Hospital | 1524 | 2026-01-26 | 2026-07-08 |
| Regular Physical Exercise in Patients With Symptomatic Intracranial Arterial Stenosis Regular physical exercise, Control group - Ischemic Stroke, Transient Ischemic Attack | Phase 3 | Active not recruiting | Capital Medical University | 1300 | 2024-10-10 | 2025-11-25 |
| Ticagrelor Based De-Escalation of Dual Antiplatelet Therapy in Ischemic Stroke Ticagrelor 60 + Aspirin, Ticagrelor 90 + aspirin - Ischemic Stroke, Transient Ischemic Attack | Phase 2 / Phase 3 | Recruiting | Mazandaran University of Medical Sciences | 100 | 2024-04-01 | 2025-04-27 |
| Efficacy of Ticagrelor Plus Aspirin in Mild Non-cardioembolic Ischemic Stroke Ticagrelor 90mg, Clopidogrel 75 mg - Ischemic Stroke, Transient Ischemic Attack | Phase 3 | Completed | Mazandaran University of Medical Sciences | 90 | 2021-08-08 | 2023-10-19 |
| NBP in Patients With Moyamoya Disease of High Risk for Ischemic Cerebrovascular Events dl-3-n-butylphthalide (NBP), Normal Saline 0.9% Infusion Solution - Moyamoya Disease, Ischemic Cerebral Infarction | Phase 3 | Unknown | yuanli Zhao | 450 | 2020-01-01 | 2019-12-19 |
| Clopidogrel With Aspirin in High-risk Patients With Acute Non-disabling Cerebrovascular Events II Ticagrelor and Aspirin, Clopidogrel and Aspirin - Stroke, Transient Ischemic Attack | Phase 3 | Completed | Beijing Tiantan Hospital | 6412 | 2019-09-23 | 2021-12-02 |
| Intensive Medical Therapy for High-risk Intracranial or Extracranial Atherosclerosis Intensive antiplatelet, Standard antiplatelet, Immediate high-intensity statin - Acute Stroke, Transient Ischemic Attack | Phase 3 | Unknown | Beijing Tiantan Hospital | 6100 | 2018-09-17 | 2023-07-18 |
| THALES - Acute STroke or Transient IscHaemic Attack Treated With TicAgreLor and ASA for PrEvention of Stroke and Death Ticagrelor, Placebo - Acute Ischaemic Stroke, Transient Ischaemic Attack | Phase 3 | Completed | AstraZeneca | 11016 | 2018-01-22 | 2020-12-22 |
| Colchicine for Prevention of Vascular Inflammation in Non-cardio Embolic Stroke Colchicine - Ischemic Attack, Transient, Stroke | Phase 3 | Completed | University College Dublin | 3154 | 2016-12-12 | 2025-03-13 |
| Platelet Reactivity in Acute Non-disabling Cerebrovascular Events Ticagrelor and Acetylsalicylic acid, Clopidogrel and Acetylsalicylic acid - Stroke, Ischemic Attack, Transient | Phase 2 / Phase 3 | Completed | Beijing Tiantan Hospital | 675 | 2015-08-01 | 2020-07-24 |
| Apixaban for Early Prevention of Recurrent Embolic Stroke and Hemorrhagic Transformation Apixaban, Warfarin - Transient Ischemic Attack, Stroke | Phase 3 | Completed | University of South Florida | 91 | 2015-04-01 | 2021-11-30 |
| Field Randomization of Nerinetide (NA-1) Therapy in Early Responders Nerinetide (NA-1), Placebo - Acute Cerebral Ischemia | Phase 3 | Completed | NoNO Inc. | 532 | 2015-03-26 | 2023-05-12 |
| Rivaroxaban Versus Aspirin in Secondary Prevention of Stroke and Prevention of Systemic Embolism in Patients With Recent Embolic Stroke of Undetermined Source (ESUS) Rivaroxaban (Xarelto, BAY59-7939), Acetylsalicylic acid (Aspirin, BAY1019036), Rivaroxaban-Placebo - Stroke | Phase 3 | Terminated | Bayer | 7213 | 2014-12-23 | 2019-01-09 |
| [SOCRATES -Acute Stroke Or Transient IsChaemic Attack TReated With Aspirin or Ticagrelor and Patient OutcomES] ticagrelor, Acetylsalicylic acid (ASA) - Acute Ischaemic Stroke, Transient Ischaemic Attack | Phase 3 | Completed | AstraZeneca | 13307 | 2014-01-07 | 2017-06-12 |
| Explore the Efficacy and Safety of Once-daily Oral Rivaroxaban for the Prevention of Cardiovascular Events in Subjects With Nonvalvular Atrial Fibrillation Scheduled for Cardioversion Rivaroxaban (Xarelto, BAY59-7939), Vitamin K antagonist (VKA) - Atrial Fibrillation | Phase 3 | Completed | Bayer | 1504 | 2012-10-01 | 2015-04-30 |
| Gadobutrol Enhanced MRA of the Supra-aortic Vessels Gadobutrol (Gadovist, BAY86-4875) - Carotid Stenosis | Phase 3 | Completed | Bayer | 479 | 2011-05-12 | 2019-01-04 |
| Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial Clopidogrel, placebo - Ischemic Attack, Transient | Phase 3 | Terminated | University of California, San Francisco | 4881 | 2010-05-28 | 2018-12-04 |
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Stroke (23) · Ischemic Stroke (11) · Atrial Fibrillation (3) · Atherosclerosis (2) · Carotid Stenosis (2) · Cerebral Infarction (2) · Cerebrovascular Disorders (2) · Hypertension (2) · Ischemia (2) · Recurrence (2) · Thromboembolism (2) · Brain Infarction (1) · Brain Ischemia (1) · Cataplexy (1)
Brain Diseases (36) · Cardiovascular Diseases (36) · Central Nervous System Diseases (36) · Nervous System Diseases (36) · Brain Ischemia (35) · Vascular Diseases (35) · Cerebrovascular Disorders (34) · Pathologic Processes (12) · Pathological Conditions, Signs and Symptoms (12) · Stroke (10) · Heart Diseases (5) · Arterial Occlusive Diseases (4) · Embolism and Thrombosis (4) · Infarction (4) · Ischemia (4)
Aspirin (10) · Clopidogrel (7) · Ticagrelor (5) · Warfarin (4) · Rivaroxaban (2) · disufenton sodium (2) · 3-n-butylphthalide (1) · Acetaminophen (1) · Atorvastatin (1) · Cardiac Rehabilitation (1) · Cerebral Revascularization (1) · Cilostazol (1) · Colchicine (1) · Control Groups (1) · Saline Solution (1)
AstraZeneca (4) · Beijing Tiantan Hospital (4) · Bayer (3) · Assistance Publique - Hôpitaux de Paris (2) · Boston Scientific Corporation (2) · Mazandaran University of Medical Sciences (2) · Asan Medical Center (1) · Capital Medical University (1) · Codman & Shurtleff (1) · First Affiliated Hospital of Wannan Medical College (1) · Hanyang University Guri Hospital (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · Merck Sharp & Dohme LLC (1) · NMT Medical (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1)
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Alastair M Buchan (1) · Anthony Furlan, MD (1) · Anthony S. Kim, MD, MAS (1) · Athena Sharifi-Razavi (1) · Bum Joon Kim, Ph.D. (1) · Cheryl Fontana, BSN (1) · David Holmes, MD (1) · Dawn M. Bravata, MD (1) · J. Donald Easton, MD (1) · James Kennedy (1) · Jim Christenson, M.D. (1) · L. Nelson Hopkins, MD (1)
PMID 29915123, PMID 35538232, PMID 16467546, PMID 17050890, PMID 17687131, PMID 17931979, PMID 18353175, PMID 18774745, PMID 19683639, PMID 20542776, PMID 21051670, PMID 21242484, PMID 21885958, PMID 22068990, PMID 22221076, PMID 22334806, PMID 22417252, PMID 22968110, PMID 23101451, PMID 23128283, PMID 23237679, PMID 23325525, PMID 23500276, PMID 23803136, PMID 23879752, PMID 24458967, PMID 24699050, PMID 25082808, PMID 25147037, PMID 25399274, PMID 25803346, PMID 25957224, PMID 26012640, PMID 26330567, PMID 26464429, PMID 26627989, PMID 27001965, PMID 27160892, PMID 27160944, PMID 27328699, PMID 27613582, PMID 27738237, PMID 27899747, PMID 28238711, PMID 28289237, PMID 28381198, PMID 28455318, PMID 28655834, PMID 28720658, PMID 28959461
1UG3NS133209-01A1 (1), 2015 (1), 2016 (1)