15 completed, 2 terminated, 2 unknown, 1 recruiting. 20 Phase 2, 7 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 20 | Completed 15, Terminated 2, Unknown 2, Recruiting 1 |
| Phase 3 | 7 | Completed 4, Recruiting 1, Terminated 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
Follow Ischemic Attack, Transient: new trials by email Literature Review of Ischemic Attack, Transient trials Research Report on Ischemic Attack, Transient
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| European Blood Pressure Intensive Control After Stroke anti-hypertensive, home blood pressure measurement, telemonitoring and medication titration, Standard of Care Blood Pressure Management with Antihypertensives - Ischemic Stroke, Transient Ischemic Attack | Phase 2 | Unknown | University College Dublin | 142 | 2024-05-02 | 2024-07-11 |
| Ticagrelor Based De-Escalation of Dual Antiplatelet Therapy in Ischemic Stroke Ticagrelor 60 + Aspirin, Ticagrelor 90 + aspirin - Ischemic Stroke, Transient Ischemic Attack | Phase 2 / Phase 3 | Recruiting | Mazandaran University of Medical Sciences | 100 | 2024-04-01 | 2025-04-27 |
| A Study on BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel BMS-986177, Placebo, Clopidogrel - Acute Ischemic Stroke, Transient Ischemic Attack (TIA) | Phase 2 | Completed | Bristol-Myers Squibb | 2366 | 2019-01-27 | 2023-06-12 |
| Platelet Reactivity in Acute Non-disabling Cerebrovascular Events Ticagrelor and Acetylsalicylic acid, Clopidogrel and Acetylsalicylic acid - Stroke, Ischemic Attack, Transient | Phase 2 / Phase 3 | Completed | Beijing Tiantan Hospital | 675 | 2015-08-01 | 2020-07-24 |
| Dabigatran Following Transient Ischemic Attack and Minor Stroke Dabigatran, Acetylsalicylic acid - Transient Ischemic Attack, Minor Ischemic Stroke | Phase 2 | Completed | University of Alberta | 300 | 2015-01-01 | 2019-01-30 |
| Rivaroxaban Versus Warfarin in Acute Ischemic Stroke With Atrial Fibrillation Rivaroxaban, Warfarin - Ischemic Stroke, Transient Ischemic Attack | Phase 2 | Completed | Asan Medical Center | 195 | 2014-01-01 | 2017-02-08 |
| Revacept in Symptomatic Carotid Stenosis Revacept, Placebo - Carotid Stenosis, Atherosclerosis | Phase 2 | Completed | AdvanceCor GmbH | 158 | 2013-03-08 | 2021-01-28 |
| NUTRITION: Natural Tocotrienol Against Ischemic Stroke Event Vitamin E tocotrienol (TCT) capsules ; Low dose Aspirin, Placebo vehicle control - Ischemic Stroke, Transient Ischemic Attack (TIA) | Phase 1 / Phase 2 | Completed | Andrew Slivka | 210 | 2012-03-01 | 2021-09-20 |
| Dabigatran Treatment Following Transient Ischemic Attack and Minor Stroke Dabigatran 110/150 mg BID - Transient Ischemic Attack, Minor Ischemic Stroke | Phase 2 | Completed | University of Alberta | 53 | 2012-02-01 | 2014-10-30 |
| Program of Rehabilitative Exercise and Education to Avert Vascular Events After Non-disabling Stroke or Transient Ischemic Attack: A Multi-site RCT PREVENT program, Usual Care - Transient Ischemic Attack, Non-disabling Stroke | Phase 2 | Completed | Marilyn MacKay-Lyons | 187 | 2011-10-30 | 2018-03-23 |
| A Study Evaluating Safety and Tolerability of YM150 Compared to Warfarin in Subjects With Atrial Fibrillation YM150, Warfarin - Atrial Fibrillation | Phase 2 | Completed | Astellas Pharma Inc | 1280 | 2009-06-01 | 2011-01-20 |
| Diagnosis and Treatment of Sleep Apnea in Cerebrovascular Disease CPAP Therapy for Newly Diagnosed Obstructive Sleep Apnea (OSA) - Obstructive Sleep Apnea, Stroke | Phase 2 / Phase 3 | Completed | VA Office of Research and Development | 225 | 2008-12-23 | 2017-06-14 |
| VISSIT Intracranial Stent Study for Ischemic Therapy Pharos Vitesse Neurovascular Stent System (Stent implantation) + Medical therapy (Aspirin and Clopidogrel), Aspirin and Clopidogrel (Medical therapy) - Ischemic Stroke, Transient Ischemic Attack | Phase 2 / Phase 3 | Terminated | Codman & Shurtleff | 125 | 2008-10-01 | 2015-02-20 |
| AtriCure Exclusion of the LAA in Patients Undergoing Concomitant Cardiac Surgery AtriCure LAA Exclusion System - Left Atrial Appendage Exclusion | Phase 2 | Completed | AtriCure, Inc. | 70 | 2008-09-01 | 2013-06-04 |
| Effects of Oral Levosimendan on Ambulatory Electrocardiographic Variables Levosimendan, Placebo - Transient Ischemic Attack, Stroke | Phase 2 | Completed | Orion Corporation, Orion Pharma | 32 | 2008-08-01 | 2009-11-25 |
| WATCHMAN Left Atrial Appendage System for Embolic PROTECTion in Patients With Atrial Fibrillation WATCHMAN Left Atrial Appendage Closure Technology, Warfarin - Atrial Fibrillation, Stroke | Phase 2 / Phase 3 | Completed | Boston Scientific Corporation | 800 | 2005-02-01 | 2015-05-15 |
| Diagnosis and Treatment of Sleep-Disordered Breathing in the Homes of Patients With Transient Ischemic Attack auto-titrating continuous positive airway pressure - Transient Ischemic Attack, Sleep Apnea | Phase 2 | Completed | Yale University | 62 | 2004-11-01 | 2009-03-03 |
| Evaluation of the STARFlex® Septal Closure System in Patients With a Stroke or TIA Due to the Possible Passage of a Clot of Unknown Origin Through a Patent Foramen Ovale (PFO) STARFlex septal closure system, Best medical therapy - Patent Foramen Ovale, Stroke | Phase 2 / Phase 3 | Unknown | NMT Medical | 900 | 2003-06-01 | 2008-12-30 |
| Fast Assessment of Stroke and Transient Ischemic Attack to Prevent Early Recurrence (FASTER) Aspirin, Clopidogrel, Simvastatin - Transient Ischemic Attack, Stroke | Phase 2 / Phase 3 | Completed | University of Calgary | 500 | 2003-05-01 | 2008-04-08 |
| E-Selectin Nasal Spray to Prevent Stroke Recurrence E-Selectin nasal spray - Cerebrovascular Accident, Transient Ischemic Attack | Phase 2 | Terminated | National Institute of Neurological Disorders and Stroke (NINDS) | 60 | 2001-03-01 | 2010-05-04 |
Stroke (13) · Ischemic Stroke (6) · Atrial Fibrillation (3) · Hypertension (2) · Recurrence (2) · Sleep Apnea Syndromes (2) · Amaurosis Fugax (1) · Atherosclerosis (1) · Brain Ischemia (1) · Camurati-Engelmann Syndrome (1) · Carotid Stenosis (1) · Foramen Ovale, Patent (1) · Heart Septal Defects, Atrial (1) · Ischemia (1)
Brain Diseases (20) · Cardiovascular Diseases (20) · Central Nervous System Diseases (20) · Cerebrovascular Disorders (20) · Nervous System Diseases (20) · Vascular Diseases (20) · Brain Ischemia (19) · Pathological Conditions, Signs and Symptoms (7) · Pathologic Processes (6) · Heart Diseases (5) · Stroke (4) · Arrhythmias, Cardiac (3) · Apnea (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Disease Attributes (2)
Aspirin (7) · Clopidogrel (4) · Warfarin (3) · Dabigatran (2) · Antihypertensive Agents (1) · BID protein, human (1) · Capsules (1) · Control Groups (1) · Revacept (1) · Rivaroxaban (1) · Simendan (1) · Simvastatin (1) · Thrombin Time (1) · Ticagrelor (1) · milvexian (1)
University of Alberta (2) · AdvanceCor GmbH (1) · Andrew Slivka (1) · Asan Medical Center (1) · Astellas Pharma Inc (1) · AtriCure, Inc. (1) · Beijing Tiantan Hospital (1) · Boston Scientific Corporation (1) · Bristol-Myers Squibb (1) · Codman & Shurtleff (1) · Marilyn MacKay-Lyons (1) · Mazandaran University of Medical Sciences (1) · NMT Medical (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1) · Orion Corporation, Orion Pharma (1)
United States (9) · Canada (5) · Germany (5) · Czechia (3) · Hungary (3) · South Korea (3) · United Kingdom (3) · Australia (2) · Austria (2) · China (2) · Finland (2) · France (2) · Israel (2) · Japan (2) · Poland (2)
Alastair M Buchan (1) · Anthony Furlan, MD (1) · Byung-Woo Yoon, PhD (1) · David Holmes, MD (1) · Dawn M Bravata, MD (1) · Dawn M. Bravata, MD (1) · Eung-Gyu Kim, PhD (1) · Holger Poppert, Prof. Dr. (1) · Ian M Loftus, MD (1) · Irja Korpela (1) · Jaekwan Cha, PhD (1) · James Kennedy (1) · Keun-Sik Hong, PhD (1) · Kyung-Ho Yu, PhD (1)
PMID 17931979, PMID 19683639, PMID 21051670, PMID 21143864, PMID 21242484, PMID 21885958, PMID 21906756, PMID 22334806, PMID 22417252, PMID 22968110, PMID 23325525, PMID 23500276, PMID 24458967, PMID 25147037, PMID 25346499, PMID 25399274, PMID 25803346, PMID 26082815, PMID 26304866, PMID 26627989, PMID 28381198, PMID 28585903, PMID 28892526, PMID 31171523, PMID 31752643, PMID 32052517, PMID 32098609, PMID 32587571, PMID 34788569, PMID 35695006, PMID 35902169, PMID 36398903, PMID 36907985, PMID 38038437, PMID 38101902, PMID 39788764