30 completed, 4 unknown, 2 not yet recruiting, 2 terminated. 39 Phase 3, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 39 | Completed 30, Unknown 4, Not yet recruiting 2, Terminated 2, Recruiting 1 |
| Phase 2 | 5 | Completed 4, Unknown 1 |
Follow Intraabdominal Infections: new trials by email Literature Review of Intraabdominal Infections trials Research Report on Intraabdominal Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Piperacillin/Tazobactam Versus Ceftriaxone and Metronidazole for Children With Perforated Appendicitis Piperacillin/Tazobactam, Ceftriaxone + Metronidazole - Appendicitis Perforated, Appendectomy, Laparoscopic | Phase 3 | Not yet recruiting | McMaster Children's Hospital | 180 | 2027-04-01 | 2026-10-09 |
| Study to Assess the Efficacy and Safety of Meropenem and Pralurbactam in CIAI Meropenem and Pralurbactam, Saline, Ceftazidime-avibactam - Intra-abdominal Infections | Phase 3 | Not yet recruiting | Qilu Pharmaceutical Co., Ltd. | 786 | 2024-10-31 | 2024-10-09 |
| Intravenous Ketorolac Vs. Morphine In Children With Acute Abdominal Pain Ketorolac Tromethamine, Morphine Sulfate, normal saline - Acute Pain, Abdomen, Acute | Phase 3 | Recruiting | University of Calgary | 495 | 2024-05-27 | 2024-06-24 |
| Comparison of Ketorolac at Three Doses in Children With Acute Pain Ketorolac Tromethamine - Acute Pain, Abdominal Pain | Phase 3 | Completed | Hamilton Health Sciences Corporation | 171 | 2023-06-01 | 2025-07-09 |
| Pharmacokinetics of Meropenem and Aztreonam After Intraperitoneal Administration Via Cycler-therapy in APD Patients Without Peritonitis Meropenem 1000 mg, Aztreonam 2000 mg, automated peritoneal dialysis with following long time dwell - Peritoneal Dialysis Associated Peritonitis, Peritoneal Dialysis (PD) | Phase 2 / Phase 3 | Completed | Karl Landsteiner Insitute for Nephrology and Haemato-Oncology | 12 | 2021-08-31 | 2025-08-11 |
| Ketorolac for Moderate to Severe Abdominal Pain in Children Ketorolac Tromethamine 10 MG/ML, Morphine Sulfate 10Mg/1mL Injection - Abdominal Pain, Appendicitis | Phase 3 | Completed | Hamilton Health Sciences Corporation | 105 | 2021-05-05 | 2023-02-28 |
| Sulopenem Versus Ertapenem for Complicated Intra-abdominal Infection (cIAI) Ertapenem, Sulopenem-Etzadroxil/Probenecid, Ciprofloxacin - Intra Abdominal Infections | Phase 3 | Completed | Iterum Therapeutics, International Limited | 674 | 2018-09-18 | 2020-12-01 |
| Non-operative Treatment of Acute Non-perforated Appendicitis Meronem and flagyl, Appendectomy - Acute Appendicitis | Phase 2 / Phase 3 | Completed | King Edward Medical University | 180 | 2018-09-01 | 2021-02-18 |
| Two Strategies of Primary Prophylaxis of Spontaneous Bacterial Peritonitis in Severe Cirrhotic Patients With Ascites Rifaximin, Placebo - Cirrhosis, Ascites | Phase 3 | Completed | Centre Hospitalier Universitaire de Besancon | 160 | 2018-06-05 | 2025-04-10 |
| Phase 3 Study of Reltecimod vs Placebo in Patients With Sepsis-associated Acute Kidney Injury Reltecimod 0.5 mg/kg, Placebo - Acute Kidney Injury, Peritonitis | Phase 3 | Terminated | Atox Bio Ltd | 58 | 2018-05-24 | 2021-10-12 |
| Study of Primary Fascial Closure Rate in Patients With Open Abdomen Treated With Abthera Versus Barker Technique Abthera, Barker - Abdominal Trauma, Abdominal Sepsis | Phase 3 | Unknown | Sociedade Brasileira de Atendimento Integrado ao Trauma | 94 | 2017-07-01 | 2017-04-25 |
| Study of Ceftolozane/Tazobactam (MK-7625A) in Combination With Metronidazole in Japanese Participants With Complicated Intra-abdominal Infection (MK-7625A-013) MK-7625A 1.5 g (ceftolozane 1 g/tazobactam 0.5 g), metronidazole 500 mg - Intra-abdominal Infection, Complicated Intra-abdominal Infection | Phase 3 | Completed | Merck Sharp & Dohme LLC | 100 | 2016-04-08 | 2018-08-09 |
| The Onset Time of Rocuronium in Emergency and Elective Surgery Rocuronium elective surgery, Rocuronium emergency surgery, Propofol - Inguinal Hernia, Acute Appendicitis | Phase 3 | Unknown | Diskapi Yildirim Beyazit Education and Research Hospital | 50 | 2015-12-01 | 2015-12-18 |
| Efficacy, Safety, Tolerability of Vabomere Compared to Best Available Therapy in Treating Serious Infections in Adults Vabomere, Best Available Therapy - Urinary Tract Infection Complicated, Acute Pyelonephritis | Phase 3 | Completed | Rempex (a wholly owned subsidiary of Melinta Therapeutics, Inc.) | 77 | 2014-07-01 | 2019-03-04 |
| Effect Study of Tigecycline to Treat Severe Sepsis and Septic Shock glycopeptide plus carbapenem, Haizheng Li Xing ® plus tazocin ® - Abdominal Infection | Phase 2 / Phase 3 | Unknown | Tianjin Medical University Cancer Institute and Hospital | 100 | 2014-05-01 | 2014-07-16 |
| Antibiotic Safety (SCAMP) ampicillin and metronidazole and gentamicin, ampicillin and gentamicin and clindamycin, gentamicin and Piperacillin- tazobactam - Complicated Intra Abdominal Infections | Phase 2 / Phase 3 | Completed | Michael Cohen-Wolkowiez | 260 | 2013-12-01 | 2019-05-30 |
| Feasibility of Outpatient Appendectomy for Acute Appendicitis outpatient surgery - Acute Appendicitis | Phase 3 | Completed | Centre Hospitalier Universitaire, Amiens | 120 | 2013-04-01 | 2025-09-22 |
| Laparoscopic Appendectomy by Multi-port vs Single Port. Single incision laparoscopic appendectomy, Multiport laparoscopic appendectomy - Acute Appendicitis | Phase 3 | Unknown | Associazione Chirurghi Ospedalieri Italiani | 300 | 2013-03-01 | 2012-11-05 |
| A Phase 3 Study Of Intravenous Metronidazole For Intrabdominal Infection Metronidazole, Ceftriaxone sodium - Intra-abdominal Infections | Phase 3 | Completed | Pfizer | 38 | 2011-11-01 | 2014-01-24 |
| Duration of Antibiotic Therapy in the Treatment of Severe Postoperative Peritonitis Admitted in ICU Duration of antibiotic therapy limited to 8 days - Postoperative Peritonitis | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 244 | 2011-05-01 | 2015-12-09 |
Showing 20 of 39. Sign in to see all of them.
Appendicitis (17) · Peritonitis (10) · Abdominal Pain (5) · Abdomen, Acute (2) · Abdominal Abscess (2) · Acute Pain (2) · Bacterial Infections and Mycoses (2) · Cholecystitis (2) · Cross Infection (2) · Emergencies (2) · Pancreatitis (2) · Sepsis (2) · Abdominal Injuries (1) · Acute Kidney Injury (1)
Infections (38) · Digestive System Diseases (26) · Cecal Diseases (17) · Gastroenteritis (17) · Gastrointestinal Diseases (17) · Intestinal Diseases (17) · Pathological Conditions, Signs and Symptoms (16) · Pathologic Processes (12) · Peritoneal Diseases (11) · Disease Attributes (6) · Neurologic Manifestations (6) · Signs and Symptoms (6) · Pain (5) · Signs and Symptoms, Digestive (5)
Metronidazole (9) · Meropenem (4) · Amoxicillin-Potassium Clavulanate Combination (3) · Ceftriaxone (3) · Doripenem (3) · Ertapenem (3) · Ketorolac Tromethamine (3) · Moxifloxacin (3) · Piperacillin, Tazobactam Drug Combination (3) · Saline Solution (3) · Amoxicillin (2) · Morphine (2) · Sodium Chloride (2) · AB103 (1) · Acetylcysteine (1)
Bayer (2) · Hamilton Health Sciences Corporation (2) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (2) · Merck Sharp & Dohme LLC (2) · All India Institute of Medical Sciences (1) · Assistance Publique - Hôpitaux de Paris (1) · Associazione Chirurghi Ospedalieri Italiani (1) · Atox Bio Ltd (1) · Centre Hospitalier Universitaire de Besancon (1) · Centre Hospitalier Universitaire, Amiens (1) · Chinese University of Hong Kong (1) · Diskapi Yildirim Beyazit Education and Research Hospital (1) · Heidelberg University (1) · Hospital Universitario Virgen de la Arrixaca (1) · Iterum Therapeutics, International Limited (1)
United States (8) · Canada (6) · China (5) · France (5) · Argentina (3) · Latvia (3) · Brazil (2) · Bulgaria (2) · Chile (2) · Colombia (2) · Czechia (2) · Germany (2) · Greece (2) · Hungary (2) · Italy (2)
Mohamed Eltorki, MBChB (2) · Alexandra Heurgue-Berlot, MD (1) · Alexandre Louvet, MD, PhD (1) · Anthony Y Teoh, FRCSEd (Gen) (1) · Azra Bihorac, MD (1) · Barbara Culbreath, RN (1) · Christophe Bureau, MD, PhD (1) · Claire Francoz, MD (1) · Didier Payen, MD (1) · Dr Govind K Makharia, MD, DM, DNB (1) · Edouard Bardou-Jacquet, MD (1) · Eric Nguyen-Khac, MD, PhD (1)
PMID 19670912, PMID 20211892, PMID 17359318, PMID 17916243, PMID 19036670, PMID 20663130, PMID 21339413, PMID 22533576, PMID 23154391, PMID 23386239, PMID 23616495, PMID 23772043, PMID 24022431, PMID 25073872, PMID 25442806, PMID 25862039, PMID 25969531, PMID 25992746, PMID 27437029, PMID 29356761, PMID 29484469, PMID 30270406, PMID 30528561, PMID 31096041, PMID 33565042, PMID 33902072, PMID 35383071, PMID 40653111, PMID 40913503, PMID 41066173
2009 (2), R01GM081510 (1)