222 completed, 120 unknown, 29 recruiting, 28 terminated. 161 Not applicable, 77 Phase 2, 31 Phase 3, 26 Phase 1, 24 Phase 4.
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Multicenter Safety and Immunogenicity Window-of-opportunity Phase 1 Interventional Trial Assessing the Combination of IDH1 Vaccine (IDH1-vac) and Vorasidenib in Adult Patients With Recurrent IDH1R132H-mutant Astrocytoma, Grade 2 - 4 (iVOCAL) IDH1R132H-vac, Vorasidenib 40 mg Oral Tablet, Aldara - Imiquimod 5% - Recurrent IDH1R132H-mutant Astrocytoma, Grade 2 - 4 | Phase 1 | Not yet recruiting | Heidelberg University | 45 | 2027-01-01 | 2026-10-16 |
| Animated Storytelling to Promote Colorectal Cancer Screening Short animated storytelling video - Colorectal Cancer Screening | Not applicable | Not yet recruiting | Stanford University | 3000 | 2026-09-01 | 2026-09-04 |
| Effect of Insulin Lowering on Lipogenesis Placebo, Diazoxide Oral Suspension, 2 mg per kg per dose, Deuterated water (2H2O/D2O), 70% - Hyperinsulinemia, Insulin Resistance | Phase 1 | Recruiting | Columbia University | 25 | 2026-07-01 | 2026-07-06 |
| ProspectiveMaleAYA - Frequency and Prediction of Therapy-induced Testicular Dysfunction in AYA Cancer Survivors Cancer, Reproduction | Not yet recruiting | Karolinska Institutet | 1000 | 2026-06-01 | 2026-05-29 | |
| Assessing the Effects of Cool Roofs on Indoor Environments and Health in Tavua, Fiji Cool roof - Resting Heart Rate, Blood Glucose Control | Not applicable | Not yet recruiting | Aditi Bunker | 800 | 2026-05-18 | 2026-05-18 |
| Evaluation of 7-day vs 1-day Packaging of Small Quantity Lipid-based Nutrition Supplementation (SQ-LNS) 7dp SQ-LNS, 1dp SQ-LNS - Prevention, Malnutrition, Child | Not applicable | Not yet recruiting | University of California, San Francisco | 100 | 2026-05-01 | 2026-05-14 |
| A Mentalization Based Prevention Program to Foster Well-Being and Mental Health in Pre-Adolescent Children and Their Families Lighthouse Program, Mentalization Based Skills Training, Lighthouse program parenting guidebook - Mental Health, Well-being | Not applicable | Recruiting | Svenja Taubner | 15200 | 2026-04-14 | 2026-07-30 |
| Assessing the Effects of Cool Roofs on Indoor Environments and Health in Colima, Mexico Cool roof - Resting Heart Rate, Blood Glucose Control | Not applicable | Not yet recruiting | Aditi Bunker | 800 | 2026-04-01 | 2026-03-12 |
| Assessing the Effect of Cool Roofs on Health Using Smartwatches in Colima, Mexico Cool roof - Heart Rate, All-day Steps | Not applicable | Not yet recruiting | University of Auckland, New Zealand | 800 | 2026-04-01 | 2026-03-11 |
| The LUCENT Study - LUng Lesion Assessment Via BF-UCP190F for Central and Extended Nodal Targeting No Interventions - Bronchoscopy | Not yet recruiting | Olympus Europe SE & Co. KG | 200 | 2025-12-01 | 2025-11-28 | |
| Digital Home-Based Physical Activity Promotion for Older Adults After Total Hip Arthroplasty Digital exercise program, Personal coaching for physical activity promotion - Total Hip Arthroplasty (THA), Older Adults (65 Years and Older) | Not applicable | Recruiting | Heidelberg University | 213 | 2025-09-01 | 2025-09-02 |
| Hyperspectral Imaging for Prediction of Preeclampsia Preeclampsia (PE) Risk, Preeclampsia | Recruiting | Heidelberg University | 1430 | 2025-08-21 | 2026-09-04 | |
| Effectiveness of an Early Reading Intervention for Young Children With Intellectual Disabilities Who Need or Use Augmentative and Alternative Communication Early Literacy Intervention in Kindergarten, Literacy Intervention in First Grade - Education | Not applicable | Active not recruiting | Ostfold University College | 120 | 2025-08-15 | 2025-12-09 |
| Supervision of Clinicians in Oncology by Psycho-oncologists : Evaluation Supervision session - Healthy Participants | Not applicable | Enrolling by invitation | Centre Hospitalier Universitaire Vaudois | 62 | 2025-08-11 | 2025-12-16 |
| Empowering Patients to Improve Safety in Polymedication Medication Management Center - Polypharmacy | Not applicable | Completed | Leiden University Medical Center | 132 | 2025-07-27 | 2026-09-02 |
| A Trial to Investigate the Effects of Cannabidiol Plus Naltrexone on Alcohol Craving in Patients With Alcohol Dependence Cannabidiol capsules, Naltrexone (drug), Placebo - Alcohol Addiction, Alcoholism | Phase 2 | Recruiting | Central Institute of Mental Health, Mannheim | 150 | 2025-07-22 | 2026-02-03 |
| Fecal Microbiota Transfer in Liver Cancer to Overcome Resistance to Atezolizumab/Bevacizumab (FLORA) Fecal microbiota transfer, Vancomycin Oral Capsule, Atezolizumab + Bevacizumab - Immunotherapy, HCC - Hepatocellular Carcinoma | Phase 2 | Recruiting | Michael Dill | 48 | 2025-07-16 | 2025-08-06 |
| Surveillance, Assessment and Detection of Influenza Associated Respiratory Infections in HIV Positive and Negative Individual in Lusaka, Zambia. Influenza, RSV | Recruiting | Centre for Infectious Disease Research in Zambia | 594 | 2025-05-20 | 2026-08-05 | |
| Endothelial Dysfunction for Prognosis In Patients With preeClampSia Hyperspectral imaging, Further markers of endothelial dysfunction - Preeclampsia (PE), Hypertensive Disorder of Pregnancy | Recruiting | Heidelberg University | 385 | 2025-05-08 | 2026-09-04 | |
| Assessing the Effect of Cool Roofs on Health Using Smartwatches in Ouagadougou, Burkina Faso Cool roof - Heart Rate, All-day Steps | Not applicable | Not yet recruiting | Institut Supérieur des Sciences de la Population | 200 | 2025-03-20 | 2025-02-24 |
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Depression (17) · Motor Activity (15) · Hypertension, Pulmonary (14) · Breast Neoplasms (10) · Malaria (10) · Carcinoma, Non-Small-Cell Lung (9) · Psychological Well-Being (9) · Heat Stress Disorders (8) · Anxiety Disorders (7) · Diabetes Mellitus (7) · Kidney Failure, Chronic (7) · Neoplasms (7) · Pancreatic Neoplasms (7) · Pulmonary Disease, Chronic Obstructive (7) · Sarcoma (7)
Exercise (9) · Rituximab (6) · Radiotherapy (5) · Amodiaquine (4) · Artesunate (4) · Cetuximab (4) · Exercise Therapy (4) · Methylene Blue (4) · Sevoflurane (4) · Cyclosporine (3) · Kidney Transplantation (3) · Mycophenolic Acid (3) · Primaquine (3) · Respiratory Rate (3) · Respiratory Therapy (3)
Germany (339) · Switzerland (16) · Austria (12) · Burkina Faso (12) · Italy (12) · France (9) · United Kingdom (9) · United States (9) · Netherlands (8) · Spain (6) · Lithuania (5) · Portugal (5) · Belgium (4) · Czechia (4) · Hungary (4)
Dieter Buchheidt, MD (7) · Collin Tukuitonga, Sir. Dr. (5) · Walter E Haefeli, MD (5) · Juergen Debus, MD PhD (4) · Luise Pruessner (4) · Steffen Hartmann (4) · Christoph Dehnert, MD (3) · Daniela Gompelmann, MD (3) · Ekkehard Gruenig, MD (3) · Felix JF Herth, MD (3) · Gerlinde Egerer, MD (3) · Klaus Herfarth, MD (3) · Klaus Herfarth, Prof. Dr. (3)
PMID 23052695, PMID 23101946, PMID 29177407, PMID 29523450, PMID 33307491, PMID 35108029, PMID 39255452, PMID 10430723, PMID 10582706, PMID 10836297, PMID 11781034, PMID 12270445, PMID 12573746, PMID 14630977, PMID 14744931, PMID 1515244, PMID 15253732, PMID 15405683, PMID 15647341, PMID 15691277, PMID 15739091, PMID 15772249, PMID 15919463, PMID 16093916, PMID 16423907, PMID 16681848, PMID 16771810, PMID 16968322, PMID 16982941, PMID 16996930, PMID 17126719, PMID 17175311, PMID 17453366, PMID 17723147, PMID 17916243, PMID 17932823, PMID 17975182, PMID 18286187, PMID 18292468, PMID 18583190, PMID 18619571, PMID 18634982, PMID 18950491, PMID 19085584, PMID 19213790, PMID 19274605, PMID 19333040, PMID 19415120, PMID 19427992, PMID 19444412
2005 (2), 2004 (1), 2008 (1), 2009 (1), 2014 (1), 2015 (1), 2016 (1), 2023 (1), K23DK140614 (1), R01NS072248 (1)