7 completed, 1 not yet recruiting, 1 terminated, 1 unknown. 10 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 10 | Completed 7, Not yet recruiting 1, Terminated 1, Unknown 1 |
Follow Hypotension, Orthostatic: new trials by email Literature Review of Hypotension, Orthostatic trials Research Report on Hypotension, Orthostatic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ceasing Alpha-blockers Early After Resection of the Prostate (The CLEAR Trial) Tamsulosin hydrochloride 0.2 mg, Placebo - Benign Prostatic Hyperplasia | Phase 4 | Not yet recruiting | Shanghai East Hospital | 400 | 2026-12-01 | 2026-09-29 |
| RaGuS Trial by Postoperative Patients Midodrine Hydrochloride, Placebo - Vasoplegic Syndrome, Sirs Due to Noninfectious Process Without Organ Dysfunction | Phase 4 | Unknown | Bürgerspital Solothurn | 50 | 2020-09-14 | 2020-06-19 |
| Lundbeck TOMs Orthostatic Hypotension Droxidopa 100 MG [Northera] - Orthostatic Hypotension, Idiopathic Parkinson Disease | Phase 4 | Completed | Alberto Espay, MD, MSc | 9 | 2019-02-11 | 2022-09-26 |
| Dose Response to the Norepinephrine Precursor Droxidopa in Hypotensive Individuals With Spinal Cord Injury Northera, Placebo - Hypotension, Orthostatic, Hypotension | Phase 4 | Completed | James J. Peters Veterans Affairs Medical Center | 22 | 2018-06-01 | 2025-03-07 |
| Efficacy and Safety of Midodrine and Atomoxetine for Neurogenic OH Midodrine, Atomoxetine - Neurogenic Orthostatic Hypotension | Phase 4 | Completed | Seoul National University Hospital | 50 | 2018-01-01 | 2019-04-05 |
| Dawn Simulation and Postural Hypotension Light - Orthostatic Hypotension | Phase 4 | Completed | VA Palo Alto Health Care System | 35 | 2016-09-01 | 2019-10-25 |
| Tilt-Table Study of the Clinical Efficacy of Midodrine in Symptomatic Orthostatic Hypotension Midodrine HCl, Placebo - Orthostatic Hypotension | Phase 4 | Completed | Shire | 24 | 2012-05-14 | 2021-06-08 |
| Study to Assess the Benefit of Midodrine in the Treatment of Patients With Neurogenic Orthostatic Hypotension Midodrine hydrochloride, Placebo - Hypotension, Orthostatic | Phase 4 | Completed | Shire | 24 | 2004-09-08 | 2021-06-14 |
| A Phase IV Study in Subjects With Neurogenic Orthostatic Hypotension midodrine hydrochloride (ProAmatine®) - Hypotension, Orthostatic | Phase 4 | Terminated | Shire | 150 | 2002-09-05 | 2021-06-29 |
| A Study for Patients With Neurogenic Orthostatic Hypotension Midodrine Hydrochloride - Hypotension, Orthostatic | Phase 4 | Completed | Shire | 140 | 1997-12-01 | 2021-06-11 |
Hypotension (1) · Parkinson Disease (1) · Prostatic Hyperplasia (1) · Spinal Cord Injuries (1) · Vasoplegia (1)
Autonomic Nervous System Diseases (10) · Cardiovascular Diseases (10) · Nervous System Diseases (10) · Orthostatic Intolerance (10) · Primary Dysautonomias (10) · Vascular Diseases (10) · Hypotension (9) · Central Nervous System Diseases (2) · Basal Ganglia Diseases (1) · Brain Diseases (1) · Genital Diseases (1) · Genital Diseases, Male (1) · Male Urogenital Diseases (1) · Movement Disorders (1) · Neurodegenerative Diseases (1)
Midodrine (6) · Droxidopa (2) · Atomoxetine Hydrochloride (1) · Tamsulosin (1) · Ultraviolet Therapy (1)
Shire (4) · Alberto Espay, MD, MSc (1) · Bürgerspital Solothurn (1) · James J. Peters Veterans Affairs Medical Center (1) · Seoul National University Hospital (1) · Shanghai East Hospital (1) · VA Palo Alto Health Care System (1)
United States (7) · South Korea (1)
Chu Kon (1) · Jill M Wecht, Ed.D (1) · Marcos Delgado, MD (1)
PMID 23845791, PMID 26492477, PMID 26953217, PMID 27372462, PMID 28327122, PMID 29223724, PMID 31107279, PMID 31334462, PMID 32145658, PMID 32307533