28 unknown, 27 recruiting, 25 completed, 12 not yet recruiting. 64 Not applicable, 12 Phase 2, 12 Phase 3, 3 Phase 4, 2 Early Phase 1.
Follow Hematoma, Subdural, Chronic: new trials by email Literature Review of Hematoma, Subdural, Chronic trials Research Report on Hematoma, Subdural, Chronic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Template-Guided Burr-Hole Drainage With Middle Meningeal Artery Coagulation for Chronic Subdural Hematoma Standard Burr-Hole Drainage Group, 3D-Printed Template-Guided Burr-Hole Drainage With Attempted MMA Coagulation Group - Chronic Subdural Hematoma | Not applicable | Not yet recruiting | The Second Hospital of Anhui Medical University | 440 | 2027-01-01 | 2026-07-23 |
| Intra-Arterial Bevacizumab as an Adjunct to Middle Meningeal Artery Embolization for Chronic Subdural Hematoma Bevacizumab (intra-arterial) - Chronic Subdural Hematoma | Phase 1 | Not yet recruiting | Dheeraj Gandhi | 18 | 2027-01-01 | 2026-07-27 |
| Frontal vs Parietal Eminence Drainage for Chronic Subdural Hematoma Frontal-region puncture drainage, Parietal Eminence region puncture drainage - Chronic Subdural Hematoma | Not applicable | Not yet recruiting | The Second Hospital of Anhui Medical University | 440 | 2027-01-01 | 2026-07-28 |
| PHIL™ Middle Meningeal Artery Embolization for First-Line Treatment of Chronic Subdural Hematoma IDE Trial PHIL™ (Precipitating Hydrophobic Injectable Liquid), Surgical evacuation - Chronic Subdural Hematomas | Not applicable | Not yet recruiting | Microvention-Terumo, Inc. | 475 | 2026-12-31 | 2026-05-08 |
| Comparative Study of Embolic Agents in Patients With Subdural Hemorrhage Undergoing Middle Meningeal Artery (MMA) Embolization Particles (polyvinyl alcohol or similar microspheres), Liquid Embolics (Onyx, n-BCA, or equivalent), Phenox Coils (Avenir UNO Helical Coil) - Chronic Subdural Hematoma, Stroke | Not applicable | Not yet recruiting | Sanford Health | 30 | 2026-09-01 | 2026-08-11 |
| Middle Meningeal Artery Embolization in Patients With Chronic Subdural Hematoma middle meningeal artery embolization - Middle Meningeal Artery Embolization, Chronic Subdural Hematomas | Not applicable | Not yet recruiting | Assiut University | 35 | 2026-09-01 | 2026-09-08 |
| Post-Market Active Surveillance and Health Economic Evaluation of Cerebrovascular Diagnostic and Therapeutic Devices Endovascular Treatment for Acute Ischemic Stroke - Acute Ischemic Stroke, Intracranial Arterial Stenosis | Not yet recruiting | Changhai Hospital | 2000 | 2026-09-01 | 2026-09-18 | |
| MMA Embolization With NeoCast for Subacute and Chronic Subdural Hematoma NeoCast Embolic System, Onyx LES, an FDA-Approved Commercial Liquid Embolic - Subdural Hematoma | Not applicable | Recruiting | Arsenal Medical, Inc. | 360 | 2026-08-13 | 2026-09-30 |
| Middle Meningeal Artery Coagulation During Burr-Hole Drainage for Chronic Subdural Haematoma (BURR-MMA) CT-Guided Intra-Operative Middle Meningeal Artery Interruption - Chronic Subdural Hematomas | Not applicable | Recruiting | University College, London | 30 | 2026-08-01 | 2026-08-04 |
| Prospective MMA Embolization Registry Middle Meningeal Artery Embolization - Chronic Subdural Hematomas | Not yet recruiting | Charite University, Berlin, Germany | 100 | 2026-07-01 | 2026-06-04 | |
| Chronic Subdural Hematoma Embolization With Detachable Coils Balt coils: (Balt USA, LLC), MMA embolization - Chronic Subdural Hemorrhage (cSDH) | Recruiting | Icahn School of Medicine at Mount Sinai | 150 | 2026-06-02 | 2026-09-25 | |
| Middle Meningeal Artery Embolisation in Chronic Subdural Hematoma Middle Meningeal Artery Embolisation - Chronic Subdural Hematoma | Not applicable | Active not recruiting | University Hospital Hradec Kralove | 200 | 2026-06-01 | 2026-09-30 |
| Study On Histoacryl Used For Embolization Of Middle Meningeal Artery (MMA) In Chronic Subdural Hematoma (CSDH) Histoacryl® - Subdural Hematoma, Subdural Hematoma, Chronic | Recruiting | Aesculap AG | 178 | 2026-04-10 | 2026-10-27 | |
| Non-Thermal Plasma to Reduce Recurrence in Chronic Subdural Hematoma Standard Surgery Protocol, Non-Thermal Plasma - Chronic Subdural Hematoma, Subdural Hematoma | Not applicable | Recruiting | Benjamín Gonzalo Rodríguez Méndez | 40 | 2026-03-02 | 2026-06-18 |
| Adjuvant Tranexamic Acid (TXA) Versus Surgery Alone for Adult Patients With Chronic Subdural Hematoma (CSDH) Tranexamic Acid (Cyklokapron) - Chronic Subdural Hematoma | Phase 2 / Phase 3 | Recruiting | St. Olavs Hospital | 274 | 2025-12-10 | 2026-07-17 |
| Prospective Multi-center Single Arm Study for Subjects With Chronic Subdural Hematoma Treated With i-ED COILs, Either Alone or in Combination With Burr-holes or Mini-craniotomy Neuro endovascular embolic coil - Chronic Subdural Hematoma, cSDH | Not yet recruiting | Kaneka Medical America LLC | 200 | 2025-11-30 | 2025-10-09 | |
| The CHALLENGER Registry Numen SILK coil embolization system - Chronic Subdural Hematoma | Suspended | Icahn School of Medicine at Mount Sinai | 100 | 2025-11-20 | 2026-10-28 | |
| Neuroendoscopy-assisted Drainage Versus Burr Hole Drainage for Chronic Subdural Hematoma Endoscope-assisted hematoma drainage, Burr hole hematoma drainage - Chronic Subdural Hematoma | Not applicable | Recruiting | Beijing Tiantan Hospital | 770 | 2025-11-19 | 2026-02-09 |
| Microfabricated Microcatheter Advantages in Middle Meningeal Artery Embolization: an Early Experience at a Single Center Matched pair Aristotle 14 guidewire and Plato 17 microcatheter, Surgeon combination preference - Chronic Subdural Hematoma, Hemorrhage Brain | Recruiting | Ohio State University | 100 | 2025-11-03 | 2026-01-07 | |
| Aspirin Continuation or Discontinuation in Conservative Treatment for Chronic Subdural Hematoma Aspirin Continuation, Aspirin Discontinuation - Chronic Subdural Hematoma | Not applicable | Recruiting | Tao Liu | 143 | 2025-10-15 | 2025-11-21 |
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Recurrence (12) · Hematoma, Subdural (9) · Intracranial Hemorrhages (5) · Hemorrhage (4) · Brain Injuries, Traumatic (3) · Bronchiolitis Obliterans Syndrome (3) · Craniocerebral Trauma (3) · Hematoma (3) · Hematoma, Subdural, Intracranial (2) · Intracranial Hypotension (2) · Postoperative Complications (2) · Stroke (2) · Atrial Fibrillation (1) · Brain Diseases (1)
Cardiovascular Diseases (110) · Disease Attributes (110) · Intracranial Hemorrhage, Traumatic (110) · Nervous System Diseases (110) · Pathologic Processes (110) · Pathological Conditions, Signs and Symptoms (110) · Trauma, Nervous System (110) · Vascular Diseases (110) · Brain Diseases (109) · Central Nervous System Diseases (109) · Cerebrovascular Disorders (109) · Chronic Disease (109) · Wounds and Injuries (109) · Craniocerebral Trauma (107) · Hematoma (107)
Tranexamic Acid (7) · Dexamethasone (5) · Atorvastatin (4) · Surgical Procedures, Operative (3) · Trephining (3) · Adrenal Cortex Hormones (2) · Bevacizumab (2) · Calcium Dobesilate (2) · Craniotomy (2) · Ethanol (2) · Fentanyl (2) · Magnesium Sulfate (2) · Propofol (2) · ethylene-vinyl alcohol copolymer (2) · Amoxicillin-Potassium Clavulanate Combination (1)
Beijing Tiantan Hospital (6) · Chinese University of Hong Kong (3) · University of New Mexico (3) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (2) · Huashan Hospital (2) · Icahn School of Medicine at Mount Sinai (2) · Kasr El Aini Hospital (2) · Oriental Neurosurgery Evidence-Based-Study Team (2) · Sahlgrenska University Hospital (2) · St. Olavs Hospital (2) · The Second Hospital of Anhui Medical University (2) · Unity Health Toronto (2) · University Hospital, Montpellier (2) · University of Manitoba (2) · Aalborg University Hospital (1)
United States (21) · China (17) · Canada (8) · France (7) · Germany (6) · Sweden (5) · Switzerland (5) · Egypt (3) · Finland (3) · Hong Kong (3) · Netherlands (3) · Belgium (2) · Japan (2) · Norway (2) · Spain (2)
Weiming Liu, M.D. (4) · Adam Arthur, MD, MPH (1) · Ajith J Thomas, MD (1) · Alejandro Tomasello, MD (1) · Alexander Coon (1) · Andreas Bartley, MD (1) · Ansaar Rai, MD (1) · Aria Nouri (1) · Asgeir Jakola, MD, PhD (1) · Benjamin Yim (1) · Carsten R Bjarkam, MD, PhD, DMSc (1) · Chandrashekhar Gendle, MD PhD (1) · Charles Matouk, MD (1) · Christian Iorio-Morin, MD (1) · Christopher Kellner (1)
PMID 12359244, PMID 19782872, PMID 26581842, PMID 27059872, PMID 27150916, PMID 27847578, PMID 28287909, PMID 28583162, PMID 28644099, PMID 29021000, PMID 30073290, PMID 30665464, PMID 32565480, PMID 33787345, PMID 35042560, PMID 35133631, PMID 35593710, PMID 35996195, PMID 36129273, PMID 36348417, PMID 36409480, PMID 36933251, PMID 36941714, PMID 37881312, PMID 37948693, PMID 37979682, PMID 38021007, PMID 38059611, PMID 38307722, PMID 38647289, PMID 38753579, PMID 38753580, PMID 38753581, PMID 38852600, PMID 39565980, PMID 39815109, PMID 40024327, PMID 40287938, PMID 40335147, PMID 40471557, PMID 41254694, PMID 41326886, PMID 41546119, PMID 41608698, PMID 41608724, PMID 41628070, PMID 41845395, PMID 41985955, PMID 41999149, PMID 42055825
2023 (2), 2009 (1), 2015 (1), 2017 (1), UG3NS128397 (1), UH3NS128397 (1)