4 unknown, 1 completed, 1 enrolling by invitation. 3 Phase 2, 2 Not applicable, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Unknown 2, Completed 1 |
| Not applicable | 2 | Enrolling by invitation 1, Unknown 1 |
| Early Phase 1 | 1 | Unknown 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Study on Deep Cervical Lymphatic Trunk Decompression Combined With Mid-Cervical Deep Lymph Node-External Jugular Vein Anastomosis for Alzheimer's Disease Treatment Bilateral Cervical Deep Lymphatic Trunk Decompression Combined with Mid-Cervical Deep Lymph Node-External Jugular Vein Anastomosis for Alzheimer's Disease - Alzheimer's Disease | Not applicable | Enrolling by invitation | Oriental Neurosurgery Evidence-Based-Study Team | 45 | 2025-01-08 | 2026-02-19 |
| To Evaluate the Therapeutic Efficacy of Hydrated Amniotic Membrane in Promoting Closure of Refractory Macular Holes. Hydrated Amniotic Membrane Plug, ILM filling, Conventional ILM peeling - Macular Holes | Not applicable | Unknown | Oriental Neurosurgery Evidence-Based-Study Team | 80 | 2022-06-01 | 2022-05-31 |
| 18F-S16 PET/CT in Healthy Volunteers and Patients With Neurodegenerative Dementia 18F-S16 - Neurodegenerative Dementia | Early Phase 1 | Unknown | Oriental Neurosurgery Evidence-Based-Study Team | 30 | 2017-08-20 | 2018-08-08 |
| 11C-PIB PET/CT in Patients With Parkinson's Disease and Parkinsonian Dementia Syndromes 11C-PiB - Parkinson Disease | Phase 2 | Unknown | Oriental Neurosurgery Evidence-Based-Study Team | 200 | 2017-07-12 | 2018-06-13 |
| The Clinical Study of Atorvastatin and Dexamethasone on Treatment for Chronic Subdural Hematoma in the Patients With Coagulation Disorders Atorvastatin, Atorvastatin and Dexamethasone - Chronic Subdural Hematoma | Phase 2 | Unknown | Oriental Neurosurgery Evidence-Based-Study Team | 60 | 2014-07-01 | 2015-03-26 |
| Effect and Safety Study of Atorvastatin to Treat Chronic Subdural Hematoma Atorvastatin, placebo - Chronic Subdural Hematoma | Phase 2 | Completed | Oriental Neurosurgery Evidence-Based-Study Team | 200 | 2013-12-01 | 2016-10-25 |
Hematoma, Subdural, Chronic (2) · Cognitive Dysfunction (1) · Dementia (1) · Parkinson Disease (1) · Retinal Perforations (1)
Atorvastatin (2) · 2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole (1) · Amyloid beta-Protein Precursor (1) · Dexamethasone (1)
China (6)
Hua Yan, MD,PhD (1) · Li Cai, MD (1) · Shuo Gao, MD (1)
PMID 26077718, PMID 26581842, PMID 29996134, PMID 30046111, PMID 30055243, PMID 30073290, PMID 30853828, PMID 35133631, PMID 35484910, PMID 36528776, PMID 36593948, PMID 36683509, PMID 38430054, PMID 39222666, PMID 39491236