28 completed, 13 unknown, 3 recruiting, 3 terminated. 27 Not applicable, 6 Phase 2, 4 Phase 1, 3 Phase 4, 2 Phase 3.
Follow Headache, Migraine: new trials by email Literature Review of Headache, Migraine trials Research Report on Headache, Migraine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treatment Response to GON Pulsed Radiofrequency in Elderly Patients With Chronic Migraine Headache, Migraine | Not yet recruiting | Ankara City Hospital Bilkent | 100 | 2026-03-01 | 2026-02-10 | |
| Adolescent Lifestyle Medicine Headache Study Lifestyle Medicine Group Medical Visits - Headache, Migraine | Not applicable | Enrolling by invitation | MaineHealth | 50 | 2026-02-10 | 2026-05-06 |
| Migraines Accepted Laser Acupuncture Compared in Blood Test of MMP2 and CGRP Laser Pen, Observation - Headache, Migraine | Not applicable | Recruiting | Taichung Veterans General Hospital | 60 | 2025-04-07 | 2026-09-30 |
| Trial Designs for Evaluating Migraine Treatment Active drug for acute migraine treatment, Placebo Oral Tablet - Migraine With Aura, Migraine Without Aura | Not applicable | Recruiting | University of Aarhus | 128 | 2024-11-13 | 2026-04-13 |
| Stellate Ganglion Blockade for Refractory Chronic Migraine Procedure/Surgery: Ultrasound-Guided Stellate Ganglion Block - Headache, Migraine, Chronic Migraine Headache | Not applicable | Completed | Ankara City Hospital Bilkent | 42 | 2024-03-06 | 2026-09-09 |
| Cross-cultural Adaptation, Reliability and Validity of the Turkish Version of the Headache Disability Questionnaire Survey study - Headache, Headache Disorders | Completed | Gazi University | 130 | 2024-01-01 | 2025-04-08 | |
| Intranasal Ketorolac Trial Ketorolac, Prochlorperazine, Diphenhydramine - Headache, Migraine | Phase 2 | Terminated | Washington University School of Medicine | 41 | 2024-01-01 | 2026-01-16 |
| Onabotulinum Toxin A (Botox) for the Treatment of Persistent Post-Stroke and Vascular Headache Botox 200 UNT Injection, Non Botox based Standard of Care Treatments for Headache/Migraine - Stroke (CVA) or TIA, Headache, Migraine | Phase 1 | Withdrawn | University of Alberta | 2023-12-01 | 2024-09-19 | |
| Responding With Evidence and Access for Childhood Headaches CBT, Amitriptyline - Headache, Headache Disorders | Not applicable | Recruiting | Children's Hospital Medical Center, Cincinnati | 400 | 2023-08-22 | 2026-09-21 |
| Study of Two Digital Therapeutics for the Prevention of Episodic Migraine Receiving CGRP Therapy (ReMMiD-C) Click Digital Therapeutic - Migraine, Episodic Migraine | Phase 3 | Completed | Click Therapeutics, Inc. | 110 | 2023-07-21 | 2024-12-18 |
| Study of Two Digital Therapeutics for the Prevention of Episodic Migraine ReMMi-D Digital Therapeutic - Migraine, Episodic Migraine | Not applicable | Completed | Click Therapeutics, Inc. | 568 | 2023-03-28 | 2025-07-03 |
| Cross-cultural Adaptation, Reliability and Validity of the Turkish Version of the Headache Impact Questionnaire Survey study - Headache, Headache Disorders | Completed | Gazi University | 102 | 2022-11-01 | 2025-04-08 | |
| Migraine Difficult to Treat: the Importance of Psychological Care in the Chronic Patient MIDITRA - Migraine Disorders, Headache, Migraine | Not applicable | Completed | University of Valencia | 30 | 2022-10-29 | 2024-02-20 |
| Ubrogepant treatmeNt in mIgraine Patients Utilizing mOnoclonal aNtibodies Ubrogepant 50 MG [Ubrelvy], Ubrogepant 100 MG [Ubrelvy] - Headache, Migraine | Phase 4 | Unknown | Chicago Headache Center & Research Institute | 164 | 2022-09-06 | 2024-08-20 |
| The Effect of Two Different Massages on Migraine Connective tissue massage, Classical massage - Headache, Migraine, Manuel Therapy | Not applicable | Completed | Biruni University | 30 | 2022-07-18 | 2026-08-13 |
| Validating a Modified COMPASS 31questionnaire for Treatment Outcomes COMPASS 31 questionnaire - Headache, Migraine, Persistent Post Traumatic Headache | Unknown | Brooke Army Medical Center | 35 | 2022-04-15 | 2022-07-21 | |
| Headache Inducing Effect of NN414 in Migraine Patients NN414, Saline - Headache, Migraine | Not applicable | Unknown | Danish Headache Center | 16 | 2022-02-25 | 2023-02-13 |
| Monoclonal Antibody Duration of REsponse in MIgraine After Treatment Interruption Headache calendar completion - Migraine, Headache, Migraine | Unknown | Hospital Clínico Universitario de Valladolid | 200 | 2022-02-15 | 2024-04-29 | |
| Evaluating the Effectiveness of a Headache Management Program in Primary Care Settings CarePath - Headache, Migraine, Headache | Not applicable | Completed | Geisinger Clinic | 203 | 2021-12-06 | 2023-12-20 |
| Feasibility of Using Holographic Memory Resolution® (HMR) in Patients/Clients With Pain Holographic Memory Resolution® (HMR) - Chronic Pain, Headache, Migraine | Not applicable | Completed | Billings Clinic | 60 | 2021-10-25 | 2022-11-02 |
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Migraine Disorders (52) · Headache (16) · Headache Disorders (6) · Migraine with Aura (4) · Migraine without Aura (4) · Headache Disorders, Primary (3) · Tension-Type Headache (3) · Bronchiolitis Obliterans Syndrome (1) · Chronic Pain (1) · Depression (1) · Digestive System Diseases (1) · Dysmenorrhea (1) · Emergencies (1) · Epilepsy (1) · Fatigue (1)
Brain Diseases (52) · Central Nervous System Diseases (52) · Nervous System Diseases (51) · Headache Disorders, Primary (49) · Headache Disorders (46) · Pathological Conditions, Signs and Symptoms (22) · Signs and Symptoms (21) · Neurologic Manifestations (19) · Pain (19) · Pathologic Processes (3) · Cardiovascular Diseases (2) · Cerebrovascular Disorders (2) · Vascular Diseases (2) · Aneurysm (1) · Behavior (1)
Sodium Chloride (7) · Amitriptyline (2) · Cognitive Behavioral Therapy (2) · Cromakalim (2) · Diphenhydramine (2) · Longitudinal Studies (2) · Acetaminophen (1) · Adenosine (1) · Adrenomedullin (1) · Air (1) · Auriculotherapy (1) · BMS204352 (1) · Botulinum Toxins, Type A (1) · Carbon Monoxide (1) · Coping Skills (1)
Danish Headache Center (11) · Children's Hospital Medical Center, Cincinnati (3) · Ankara City Hospital Bilkent (2) · Click Therapeutics, Inc. (2) · Gazi University (2) · Amgen (1) · Anne Ducros (1) · Billings Clinic (1) · Biruni University (1) · Bnai Zion Medical Center (1) · Brooke Army Medical Center (1) · Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer (1) · Centre Hospitalier Universitaire de Besancon (1) · Chicago Headache Center & Research Institute (1) · Clinvest (1)
United States (22) · Denmark (12) · Turkey (Türkiye) (5) · France (3) · Israel (2) · Spain (2) · Canada (1) · Italy (1) · Taiwan (1)
Scott Powers, PhD (3) · Messoud Ashina (2) · Abby Rhoads, DO (1) · Apoorva Pradhan, BAMS, MPH (1) · Bradley Torphy, MD (1) · Chi Sheng Wang, M.D. (1) · Chi-Hsiang Chou, M.D. (1) · Christopher Lloyd, D.O. (1) · Debra Kimless, M.D. (1) · Eric Wright, PharmD, MPH (1) · Gerardo Serra (1) · Hao-Yuan Chang, Asst. Prof. (1)
PMID 42129417, PMID 19788468, PMID 22384463, PMID 22622909, PMID 25164919, PMID 25500317, PMID 26381856, PMID 27910097, PMID 29765218, PMID 30152015, PMID 30232673, PMID 30617735, PMID 30963506, PMID 31292608, PMID 32295400, PMID 32847403, PMID 33106278, PMID 33454126, PMID 33827963, PMID 34252916, PMID 34322089, PMID 35500528, PMID 36251971, PMID 37284181, PMID 38270379, PMID 38501895, PMID 38510483, PMID 38729773, PMID 39161224, PMID 39669537, PMID 39696036
R01AT010171 (1), R01NS101321 (1), U01AT010132 (1), UL1TR001082 (1)