14 completed, 4 unknown, 2 active not recruiting, 2 recruiting. 25 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 25 | Completed 14, Unknown 4, Active not recruiting 2, Recruiting 2, Withdrawn 2, Terminated 1 |
Follow Head and Neck Cancer: new trials by email Literature Review of Head and Neck Cancer trials Research Report on Head and Neck Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Apixaban or Enoxaparin After Head and Neck Cancer Surgery Enoxaparin, Apixaban - Venous Thromboembolism, Head and Neck Cancer | Phase 4 | Recruiting | Kiranya Arnold | 76 | 2025-10-01 | 2025-10-08 |
| Efficacy of Botox Injection of the Masticatory Muscles in Head &Neck Cancer Patients with Trismus After Radiotherapy Echo-guided Botox injection, echo-guided normal saline injection - Trismus, Head and Neck Cancer | Phase 4 | Recruiting | National Taiwan University Hospital | 120 | 2024-12-01 | 2024-12-16 |
| Impact of the Oral Microbiota on Relapse in HNSCC Patients buccal swabs - Head and Neck Cancer | Phase 4 | Active not recruiting | Institut Sainte Catherine | 100 | 2024-11-18 | 2025-02-04 |
| Effects of Minimal-Flow Sevoflurane and Multimodal Analgesia in Head and Neck Cancer Surgery Multimodal analgesia using dexmedetomidine-ketamine-lidocaine mixture, Minimal flow sevoflurane - Head and Neck Cancer, Anesthesia | Phase 4 | Unknown | National Taiwan University Hospital | 60 | 2024-08-01 | 2024-07-26 |
| Mood Disorders in Head and Neck Cancer Patients Venlafaxine - Depressive Disorder, Head and Neck Cancer | Phase 4 | Withdrawn | University of Alabama at Birmingham | 2024-01-05 | 2025-02-04 | |
| Benzydamine Oromucosal Solution in Oral Mucositis (BOOM) Benzydamine Hydrochloride 0.15% w/v oromucosal solution - Radiation-Induced Mucositis, Head and Neck Cancer | Phase 4 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 100 | 2021-12-06 | 2022-11-16 |
| A Trial of Nimotuzumab and Pinkiller Efficacy and Pain in Advanced Head and Neck Squamous Cell Carcinoma Nimotuzumab, cis-platinum, IMRT combine with cisplatin concurrent chemotherapy - Head and Neck Cancer | Phase 4 | Active not recruiting | Biotech Pharmaceutical Co., Ltd. | 171 | 2021-05-15 | 2025-03-17 |
| Nutrition and Pharmacological Algorithm for Oncology Patients Study Dexamethasone, Dronabinol, Mirtazapine - Oncologic Complications, Quality of Life | Phase 4 | Terminated | Montefiore Medical Center | 1 | 2021-03-01 | 2022-11-16 |
| Individualization of Nutritive Sensory Support Of Radiation Therapy Oral nutritional supplements (ONS) with a cooling effect + ONS without a sensor component and taste + standard diet, ONS without a sensor component and taste + standard diet, Standard diet - Radiotherapy; Complications, Head and Neck Cancer | Phase 4 | Completed | National Medical Research Radiological Centre of the Ministry of Health of Russia | 100 | 2020-12-15 | 2023-03-24 |
| Comparison of Transdermal Fentanyl and Morphine for Oral Mucositis Pain in Nasopharyngeal Cancer Patients Fentanyl, Morphine - Pain, Nasopharyngeal Carcinoma | Phase 4 | Unknown | Jiarong Chen, MD | 300 | 2020-12-01 | 2020-07-29 |
| Treating Locally Advanced Head and Neck Malignant Tumor With Anlotinib and Chemoradiotherapy Anlotinib hydrochloride capsules - Head and Neck Cancer | Phase 4 | Unknown | Sun Yat-sen University | 30 | 2020-09-01 | 2020-08-28 |
| Multimodal Pain Study in Free Flap Patients Tylenol, Oxycodone, Morphine - Head and Neck Cancer, Analgesia | Phase 4 | Completed | University of Kansas Medical Center | 30 | 2019-11-01 | 2026-07-07 |
| Pre-Operative Pregabalin for Post-Operative Pain in Head and Neck Cancer Surgery Pregabalin 150mg, Placebo - Head and Neck Cancer, Pain, Postoperative | Phase 4 | Withdrawn | Augusta University | 2019-03-22 | 2020-07-09 | |
| Continous Popliteal Block for Microvascular Free Flap Reconstruction in Ear, Nose and Throat Surgery Levobupivacaine, Saline Solution - Head and Neck Cancer, Pain, Musculoskeletal | Phase 4 | Completed | Region Skane | 24 | 2018-09-01 | 2021-04-08 |
| Perioperative Gabapentin Use In Head And Neck Mucosal Surgery Patients Gabapentin, Placebo - Head and Neck Cancer, Acute Pain | Phase 4 | Completed | Washington University School of Medicine | 123 | 2016-06-24 | 2018-08-08 |
| A New Oral salIvary equivAlent Compared to Two moisturizinG Mouth sprAys in Patients With xeRostomiA: NIAGARA Study Salivary equivalent, Aequasyal, Biotene - Xerostomia, Hyposalivation | Phase 4 | Completed | Unither Pharmaceuticals, France | 210 | 2012-01-01 | 2014-01-29 |
| Skin Changes in Head and Neck Cancer During Immuno-(Chemo-) And Radiotherapy With Erbitux® (HICARE) Erbitux®, Fractionated Radiotherapy - Head and Neck Cancer | Phase 4 | Completed | University of Heidelberg Medical Center | 139 | 2011-06-01 | 2022-05-25 |
| The Effect on an Ionic Silver Dressing in Head and Neck Patients With Malignant Fungating Wound silver-releasing dressings - Head and Neck Neoplasms, Head and Neck Cancer | Phase 4 | Unknown | National Taiwan University Hospital | 70 | 2009-01-01 | 2009-05-19 |
| Assessment of the Effects of Pressors on Graft Blood Flow After Free Tissue Transfer Surgery Epinephrine, Norepinephrine, Dobutamine - Oral Cancer, Head and Neck Cancer | Phase 4 | Completed | Oxford University Hospitals NHS Trust | 25 | 2008-10-01 | 2011-08-16 |
| Health Education Counseling With or Without Bupropion in Helping African Americans Stop Smoking smoking cessation intervention, bupropion hydrochloride, gene expression analysis - Bladder Cancer, Cervical Cancer | Phase 4 | Completed | Lisa Sanderson Cox, PhD | 540 | 2007-12-01 | 2017-11-13 |
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Head and Neck Neoplasms (25) · Lung Neoplasms (4) · Esophageal Neoplasms (3) · Mouth Neoplasms (3) · Pain, Postoperative (3) · Pancreatic Neoplasms (3) · Agnosia (2) · Carcinoma, Hepatocellular (2) · Carcinoma, Non-Small-Cell Lung (2) · Carcinoma, Renal Cell (2) · Hypopharyngeal Neoplasms (2) · Hypotension (2) · Kidney Neoplasms (2) · Laryngeal Neoplasms (2) · Leukemia (2)
Neoplasms by Site (25) · Neoplasms (24) · Pathological Conditions, Signs and Symptoms (8) · Signs and Symptoms (7) · Stomatognathic Diseases (7) · Mouth Diseases (6) · Neurologic Manifestations (6) · Digestive System Diseases (5) · Respiratory Tract Diseases (5) · Digestive System Neoplasms (4) · Gastrointestinal Diseases (4) · Lung Diseases (4) · Neoplasms by Histologic Type (4) · Otorhinolaryngologic Diseases (4) · Pathologic Processes (4)
Gabapentin (2) · Morphine (2) · Norepinephrine (2) · Acetaminophen (1) · Benzydamine (1) · Bleomycin (1) · Bupivacaine (1) · Bupropion (1) · Cetuximab (1) · Cisplatin (1) · Counseling (1) · Dexamethasone (1) · Diet Therapy (1) · Dietary Supplements (1) · Dobutamine (1)
National Taiwan University Hospital (3) · Augusta University (1) · Aziende Chimiche Riunite Angelini Francesco S.p.A (1) · Biotech Pharmaceutical Co., Ltd. (1) · Fox Chase Cancer Center (1) · Inovio Pharmaceuticals (1) · Institut Sainte Catherine (1) · Jiarong Chen, MD (1) · Kiranya Arnold (1) · Lisa Sanderson Cox, PhD (1) · Montefiore Medical Center (1) · Mt. Sinai Medical Center, Miami (1) · National Medical Research Radiological Centre of the Ministry of Health of Russia (1) · Oxford University Hospitals NHS Trust (1) · Region Skane (1)
United States (9) · France (3) · China (2) · Taiwan (2) · Finland (1) · Germany (1) · Hungary (1) · Poland (1) · Russia (1) · Sweden (1) · United Kingdom (1)
Corinne Bouteloup, Doctor (1) · James K Byrd, MD (1) · Jessica Grayson, MD (1) · Jiarong Chen, PhD (1) · Justin Tang, MD (1) · Lisa S. Cox, PhD (1) · Lisa Shnayder, MD (1) · Louise Walther Sturesson, MD, PhD (1) · Marie-Paule Vasson, Professor (1) · Melanie Townsend, M.D. (1) · Michael A Samuels, MD (1) · Ming-Hui Hung, MD (1)
PMID 21266057, PMID 21775497, PMID 22241828, PMID 22929242, PMID 23733379, PMID 23855804, PMID 25575640, PMID 29710075, PMID 33300144, PMID 34611902, PMID 34791718, PMID 37230961, PMID 39868569
2008 (1), 2019 (1), R01CA091912 (1)