81 completed, 33 unknown, 17 recruiting, 13 terminated. 64 Phase 2, 61 Phase 3, 15 Phase 1, 12 Not applicable, 9 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treatment of Low-flow Vascular Malformations With Bleomycin Electrosclerotherapy (BEST) Bleomycin Sulfate - Vascular Malformations | Phase 2 | Recruiting | Institute of Oncology Ljubljana | 140 | 2026-09-10 | 2026-10-09 |
| Microneedling Alone Versus Microneedling Coupled With Either Bleomycin or 5flourouracil in the Treatment of Plantar Warts Bleomycin, Microneedling alone, 5 fluorouracil - Warts of Foot | Not applicable | Not yet recruiting | Assiut University | 60 | 2026-06-01 | 2025-06-27 |
| Primary RPLND Versus Systemic Chemotherapy in Good-prognosis Metastatic Testicular Cancer primary RPLND for low-stage metasatatic seminoma, 3 courses of chemotherapy; Blemocin, Etoposide and Platinum (BEP) - Testicular Cancer, Seminoma | Not applicable | Recruiting | Sahlgrenska University Hospital | 160 | 2026-03-19 | 2026-03-27 |
| Injection Sclerotherapy With Bleomycin VS Doxycycline in Patients With Lymphatic Malformations Bleomycin, doxycycline (tetracycline) - Lymphatic Abnormality | Phase 2 | Not yet recruiting | Basharat Hussain | 92 | 2026-01-26 | 2026-01-06 |
| A Self-controlled Study of Bleomycin and Pingyangmycin Injection in the Treatment of Plantar Warts Hyperthermia Therapy, Pingyangmycin Injection, Bleomycin injection - Plantar Wart | Phase 4 | Active not recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 200 | 2025-10-01 | 2026-07-02 |
| Intralesional Bleomycin Sclerotherapy for Low-Flow Vascular Malformations of the Head and Neck Bleomycin (Bleocel 15) - Vascular Malformations, Venous Malformation | Phase 4 | Completed | University Of Anbar | 20 | 2025-08-25 | 2026-07-27 |
| A Randomized Controlled Trial to Evaluate the Effectiveness of Bleomycin and Cryotherapy in Treating Plantar Warts. Bleomycin injection, Cryotherapy - Verruca Plantaris | Phase 1 / Phase 2 | Recruiting | The Fourth Affiliated Hospital of Zhejiang University School of Medicine | 70 | 2024-12-25 | 2025-03-24 |
| The Effect of Reduced Bleomycin in Electrochemotherapy Treatment Bleomycin - Cutaneous Metastasis, Cutaneous Malignant Mixed Tumor | Phase 4 | Recruiting | Julie Gehl | 55 | 2024-10-29 | 2026-09-15 |
| Electrochemotherapy for Desmoid Tumors Electrochemotherapy with bleomycin - Desmoid Fibromatosis | Withdrawn | Istituto Ortopedico Rizzoli | 2024-10-17 | 2026-05-14 | ||
| Paclitaxel-Bleomycin/Etoposide/Cisplatin vs Bleomycin/Etoposide/Cisplatin in Poor-prognosis Non-seminomatous Germ Cell Tumors (NSGCT) and Unfavorable Tumor Marker Decline Paclitaxel, Bleomycin, Etoposide - Germ Cell Cancer Metastatic | Phase 2 | Recruiting | Blokhin's Russian Cancer Research Center | 60 | 2024-10-01 | 2026-10-26 |
| Low-Dose Propranolol and Bleomycin for Infantile Hemangioma (IH) Propranolol + Bleomycin, Propranolol - Infantile Hemangioma (IH) | Not applicable | Completed | Wuhan Integrated Traditional Chinese and Western Medicine Hospital | 260 | 2024-01-01 | 2025-08-05 |
| Treatment of Low-flow Venous Malformations With Electrosclerotherapy. Prospective Observational Study Bleomycin - Vascular Malformations | Recruiting | Istituto Ortopedico Rizzoli | 65 | 2023-10-28 | 2026-05-22 | |
| PRIMETEST II - Clinical Stage II A/B Seminoma Treated With RA-RPLND Robot-assisted retroperitoneal lymph node dissection, Adjuvant therapy with one cycle of cisplatin, etoposide and bleomycin - Seminoma | Phase 2 | Recruiting | Heinrich-Heine University, Duesseldorf | 60 | 2023-08-28 | 2025-09-15 |
| ECT STUDY High-grade or Initially Invasive Vulva - GinOnc-ECT Study Bleomicina - Paget Disease of the Vulva, Vulva Cancer | Phase 2 | Active not recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 18 | 2023-05-23 | 2025-08-08 |
| A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab Biospecimen Collection, Bleomycin Sulfate, Brentuximab Vedotin - Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8 | Phase 3 | Recruiting | National Cancer Institute (NCI) | 1875 | 2023-05-11 | 2026-11-02 |
| Use of Bleomycin in the Sclerotherapy of Lymphatic Malformations for Pediatric Patients Bleomycin - Lymphatic Malformation | Phase 2 | Recruiting | West China Hospital | 200 | 2023-03-08 | 2024-06-03 |
| Anti-CD30 (Brentuximab Vedotin) With AVD Versus ABVD Chemotherapy Protocol Frontline Therapy in Patients With Advanced Classical Hodgkin Lymphoma Brentuximab Vedotin + Doxorubicin, Vinblastine, and Dacarbazine, Doxorubicin, Bleomycin, Vinblastine, and Dacarbazine - Anti-CD30, Brentuximab | Not applicable | Completed | Helwan University | 60 | 2023-03-01 | 2025-09-15 |
| Brentuximab Vedotin in Early Stage Hodgkin Lymphoma Involved site radiotherapy, Doxorubicin, Bleomycin - Hodgkin Lymphoma | Phase 3 | Recruiting | University College, London | 1042 | 2022-04-14 | 2026-07-08 |
| Electrochemotherapy With Carboplatinum Plus Bleomycin Versus Bleomycin Alone in Vulvar Cancer Carboplatin, Bleomycin - Vulvar Cancer | Phase 2 | Recruiting | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 92 | 2022-04-08 | 2022-05-27 |
| Bleomycin Jet Injections in Keloids Bleomycin, Normal saline - Keloid | Phase 4 | Unknown | Erasmus Medical Center | 14 | 2022-03-18 | 2022-11-09 |
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Hodgkin Disease (50) · Lymphoma (45) · Testicular Neoplasms (14) · HIV Infections (12) · Teratoma (12) · Acquired Immunodeficiency Syndrome (11) · Lymphoma, Large B-Cell, Diffuse (10) · Lymphoma, Non-Hodgkin (9) · Endodermal Sinus Tumor (8) · Head and Neck Neoplasms (8) · Carcinoma, Embryonal (7) · Neoplasms (7) · Sarcoma, Kaposi (7) · Testicular Germ Cell Tumor (7) · Lymphoma, Follicular (6)
Children's Oncology Group (9) · M.D. Anderson Cancer Center (8) · National Institute of Allergy and Infectious Diseases (NIAID) (8) · European Organisation for Research and Treatment of Cancer - EORTC (7) · University of Cologne (7) · Children's Cancer and Leukaemia Group (4) · Inovio Pharmaceuticals (4) · Memorial Sloan Kettering Cancer Center (4) · SWOG Cancer Research Network (4) · Stanford University (4) · Copenhagen University Hospital at Herlev (3) · Institute of Oncology Ljubljana (3) · Lymphoma Trials Office (3) · Medical Research Council (3) · PCI Biotech AS (3)
United States (68) · United Kingdom (30) · Canada (19) · Italy (18) · France (15) · Australia (14) · Denmark (13) · Germany (12) · Netherlands (12) · Belgium (11) · Puerto Rico (9) · Poland (8) · Spain (8) · China (7) · Switzerland (7)
Sandra J. Horning, MD (5) · Paul Goldfarb, MD (4) · Anas Younes, MD (3) · Ruth Pettengell, MD (3) · Volker Diehl, Prof. (3) · Alessandro M Gianni, MD (2) · Andreas Engert, Prof. (2) · Christophe Ferme (2) · Gill PS (2) · H. Eghbali, MD (2) · Kara Kelly, MD (2) · Levine A (2) · Lode J. Swinnen, MD (2) · Michael Williams, MD (2)
PMID 40135712, PMID 37505794, PMID 24121121, PMID 23509310, PMID 24239220, PMID 30010775, PMID 39969278, PMID 41074963, PMID 14508361, PMID 15837968, PMID 15936157, PMID 15999362, PMID 16314615, PMID 17097834, PMID 17235042, PMID 17846017, PMID 17989384, PMID 18645482, PMID 19584400, PMID 19828373, PMID 19875337, PMID 20551376, PMID 20713848, PMID 20818855, PMID 21059637, PMID 21079154, PMID 21774708, PMID 21990399, PMID 22149921, PMID 22371887, PMID 22456397, PMID 22689804, PMID 22731832, PMID 22911615, PMID 23182987, PMID 23356491, PMID 23386127, PMID 25001888, PMID 25311218, PMID 25344361, PMID 25456363, PMID 25897153, PMID 25964643, PMID 26373676, PMID 26834240, PMID 27114593, PMID 27282998, PMID 27332902, PMID 27475428, PMID 28601705
U10CA032102 (4), P30CA016672 (3), U10CA098543 (3), U10CA180886 (3), 2023 (2), 2004 (1), 2005 (1), 2009 (1), 2014 (1), 2017 (1), 2025 (1), P30CA006973 (1), P30CA043703 (1), U01AI068636 (1), U01CA079778 (1)