15 completed, 5 unknown, 2 recruiting, 1 not yet recruiting. 7 Phase 4, 6 Phase 1, 4 Phase 2, 4 Phase 3, 2 Early Phase 1.
Follow Benzydamine: new trials by email Literature Review of Benzydamine trials Research Report on Benzydamine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oral Care Interventions in PEG-Fed Palliative Care Patients Ankaferd Hemostat, Benzydamine Hydrochloride 0.15% w/v oromucosal solution, Combined Oral Care Solution - Oral Mucosal Integrity, Palliative Care | Not applicable | Not yet recruiting | University of Yalova | 60 | 2026-09-07 | 2026-09-01 |
| Benzydamine Hydrochloride and Post-operative Sore Throat Benzydamine Hydrochloride - Sore Throat, Postoperative Care | Early Phase 1 | Recruiting | KK Women's and Children's Hospital | 106 | 2025-08-11 | 2026-08-06 |
| Benzydamine for Radiation-Induced Oral Mucositis in Patients Receiving High-Dose Radiotherapy benzydamine hydrochloride, saline mouth rinse - Radiation-induced Oral Mucositis | Phase 4 | Completed | Latakia University | 35 | 2025-07-20 | 2026-03-17 |
| Palatability Study of Five Formulations of Benzydamine HCl Lozenges benzydamine HCl - Healthy Volunteers, Palatability | Phase 1 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 120 | 2025-04-13 | 2025-09-30 |
| Study to Evaluate the Efficacy and Safety of Different Doses of Graminidin With Anesthetic, a Metered Dose Topical Spray, in the Treatment of Acute Infectious and Inflammatory Pharyngeal Diseases Compared With Drug Septolete Total, Lozenges Grammidin with anesthetic, Septolete Total - Pharyngitis Acute, Pharyngitis | Phase 2 | Recruiting | Valenta Pharm JSC | 300 | 2024-11-14 | 2025-07-10 |
| Comparison Between the Effect of Aloe Vera and Benzydamine Hydrochloride Mouth Gel on Prevention of Pain and Progression of Radiation-induced Oral Mucositis Aloe vera gel, Benzydamine Hydrochloride 0.15% Oral gel, bioadhesive gel - Radiation Indused Oral Mucositis | Phase 1 / Phase 2 | Completed | Minia University | 30 | 2023-11-01 | 2025-03-06 |
| Effect of Over-the-counter NSAIDS on Cough Reflex Sensitivity in Patients with Upper Respiratory Tract Infections Flurbiprofen Oral Lozenge, Difflam, Flurbiprofen 8.75 MG - Cough, Upper Respiratory Tract Infections | Early Phase 1 | Completed | University of Melbourne | 101 | 2023-07-01 | 2024-12-06 |
| Evaluation of the Efficacy of Aloe-Vera el Versus Bezydamine Hydrochloride in the Prevention of Radiation Induced Oral Mucositis A Randamized Controlled Clinical Trial Aloe vera gel, Benzydamine Hydrochloride 0.15% Oral gel - Head and Neck Cancer Patients Treated With Radiotherapy | Phase 4 | Completed | October 6 University | 40 | 2023-06-01 | 2025-03-17 |
| The Use of Tulsi Extract for The Management of Oral Mucositis in Head & Neck Cancer Patients Undergoing Radiotherapy tulsi extract, Benzydamine Hydrochloride - Stomatitis | Phase 2 | Unknown | Cairo University | 42 | 2022-07-01 | 2022-05-11 |
| Study for the Prevention of Oral Mucositis (SPOM) Bocaliner, Benzydamine - Oral Mucositis | Phase 1 / Phase 2 | Unknown | E2Bio Life Sciences, LLC | 100 | 2022-04-15 | 2023-09-08 |
| Preoperative Aspirin and Benzydamine Hydrochloride Gargles on Severity and Duration of Post-Operative Sore Throat Benzydamine hydrochloride, Aspirin - Sore Throat | Phase 4 | Unknown | Rehman Medical Institute - RMI | 60 | 2022-04-01 | 2022-05-12 |
| Benzydamine Oromucosal Solution in Oral Mucositis (BOOM) Benzydamine Hydrochloride 0.15% w/v oromucosal solution - Radiation-Induced Mucositis, Head and Neck Cancer | Phase 4 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 100 | 2021-12-06 | 2022-11-16 |
| Treatment of Chemotherapy and Radiotherapy Induced Oral Mucositis Benzydamine Hydrochloride, Solcoseryl and pumpkin seed oil - Mucositis Oral | Phase 3 | Unknown | Ghada zaki | 54 | 2021-12-01 | 2021-08-06 |
| Effect of St. John's Wort and Olive Oils on the Postoperative Complications Chlorhexidine Gluconate 0.12 % Mouthwash + benzydamine hydrochloride, St. John's wort oil, Virgin olive oil - Impacted Third Molar Tooth | Phase 4 | Completed | Yuzuncu Yil University | 90 | 2018-08-15 | 2021-11-01 |
| Benzydamine Hydrochloride Gargle in Reducing Propofol for ERCP Benzydamine Hydrochloride 0.15% Oral Rinse, Water - ERCP | Not applicable | Completed | Universitas Indonesia | 72 | 2018-08-01 | 2019-11-19 |
| A Novel Mouthwash Formulation CTP/BNZ With Mucus Adhesive Polymer Cetylpyridinium Chloride 0.05% + Benzydamine HCl 0.15% + mucus adhesive polymer, Cetylpyridinium Chloride 0.05% + Benzydamine HCl 0.15% - Healthy | Phase 1 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 26 | 2017-11-14 | 2020-08-05 |
| Evaluation of the Effects of Different Analgesics on Pericoronitis Pain and Quality of Life Diclofenac, Flurbiprofen, Benzydamine - Pain, Quality of Life | Phase 4 | Completed | Near East University, Turkey | 60 | 2017-11-01 | 2018-11-19 |
| Effect of Benzydamine Hydrochloride to Postoperative Sore Throat in Pediatric Patients Benzydamine Hydrochloride, Normal saline - Intubation Complication | Phase 4 | Completed | Seoul National University Hospital | 142 | 2017-03-08 | 2018-04-11 |
| Tolerability and Pharmacokinetic Study of Econazole Nitrate Plus Benzydamine HCl Vaginal Pessary Econazole nitrate 150 mg plus Benzydamine HCl 6 mg vaginal pessary, Placebo plus Econazole nitrate 150 mg vaginal pessary, Placebo plus Benzydamine HCl 6 mg vaginal pessary - Healthy Women | Phase 1 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 49 | 2016-03-04 | 2017-02-07 |
| Tolerability and Pharmacokinetic Study of Econazole Nitrate and Benzydamine HCl Intravaginal Cream Econazole nitrate 1% plus Benzydamine HCl 0.12% intravaginal cream, Placebo plus Econazole nitrate 1% intravaginal cream, Placebo plus Benzydamine HCl 0.12% intravaginal cream - Healthy | Phase 1 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 48 | 2015-09-01 | 2018-01-17 |
Showing 20 of 23. Sign in to see all of them.
Stomatitis (5) · Pharyngitis (4) · Head and Neck Neoplasms (2) · Mucositis (2) · Pain (2) · Cough (1) · Inflammation (1) · Nasopharyngitis (1) · Oral Ulcer (1) · Pericoronitis (1) · Respiratory Tract Infections (1)
Aziende Chimiche Riunite Angelini Francesco S.p.A (5) · Cairo University (1) · E2Bio Life Sciences, LLC (1) · Ghada zaki (1) · Juravinski Cancer Centre Foundation (1) · KK Women's and Children's Hospital (1) · Latakia University (1) · McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. (1) · Minia University (1) · Near East University, Turkey (1) · October 6 University (1) · Prince of Songkla University (1) · Rehman Medical Institute - RMI (1) · Seoul National University Hospital (1) · Universitas Indonesia (1)
Switzerland (4) · Egypt (2) · Turkey (Türkiye) (2) · Armenia (1) · Australia (1) · Canada (1) · Hungary (1) · Indonesia (1) · Pakistan (1) · Poland (1) · Russia (1) · Singapore (1) · South Korea (1) · Syria (1) · Thailand (1)
Milko Radicioni, MD (2) · Abdullah AlAlwani, DDS (1) · Adhrie Sugiarto, MD (1) · Ban Leong Sng (1) · Bassam Saad, PhD (1) · Hee-Soo Kim (1) · Joda Kuk, MD (1) · Milko Radicioni (1) · Mohammad Shafiq, FCPS (1) · Rama Ibrahim, PhD (1) · Stuart Mazzone, PhD (1) · Yervand Hakobyan, MD (1)
PMID 32247315, PMID 17000820, PMID 22066487, PMID 22174478, PMID 23991600, PMID 24263969, PMID 26171894, PMID 26470672, PMID 27158989, PMID 30617677, PMID 32410819, PMID 32446304, PMID 40742572