51 completed, 42 unknown, 16 recruiting, 10 not yet recruiting. 49 Not applicable, 23 Phase 4, 17 Phase 3, 6 Phase 2, 3 Phase 1.
Follow Esophageal and Gastric Varices: new trials by email Literature Review of Esophageal and Gastric Varices trials Research Report on Esophageal and Gastric Varices
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pre-emptive RTO for An Early Detected Gastric Varices in CT/MR Angiogram Trial Non-selective beta blockers, Retrograde transvenous obliteration - Gastric Varices | Not applicable | Not yet recruiting | University of California, Los Angeles | 68 | 2026-10-01 | 2026-07-02 |
| Baveno VIII Criteria for Portal Hypertension in Egyptian Patients Compensated Liver Disease, Esophageal Varices | Not yet recruiting | Assiut University | 125 | 2026-09-26 | 2026-09-25 | |
| Clinical Trial to Evaluate the Effectiveness of Liver Shear Wave Quantization Detector Spleen Stiffness Value in the Diagnosis of Esophageal Varices Chronic Liver Diseases, Spleen Stiffness | Not yet recruiting | Beijing Friendship Hospital | 246 | 2026-08-20 | 2026-08-07 | |
| Cyanoacrylate Glue Versus Absorbable Gelatin Sponge for Gastric Varices EUS-Guided Coil Embolization With Cyanoacrylate Glue and Lipiodol, EUS-Guided Coil Embolization With Absorbable Gelatin Sponge - Gastric Varices Bleeding, Gastric Varices | Not applicable | Not yet recruiting | Unity Health Toronto | 64 | 2026-08-01 | 2026-07-13 |
| Underdilated VCX-TIPS Versus EVL Plus NSBB for Secondary Prophylaxis of Variceal Bleeding in Cirrhosis Underdilated VCX-TIPS, Endoscopic Variceal Ligation, Nonselective Beta-Blockers - Liver Cirrhosis, Portal Hypertension | Not applicable | Not yet recruiting | West China Hospital | 240 | 2026-08-01 | 2026-05-14 |
| Case-Specific Health Care Professional Clinical Survey for Concerto Versa™ Detachable Coils Concerto Versa™ Detachable Coils - Arteriovenous Malformation, Gastrointestinal Bleed | Enrolling by invitation | Medtronic Endovascular | 30 | 2026-07-24 | 2026-10-15 | |
| Topical Application of Sucralfate in Promoting Healing of Esophageal Ulcers After Esophageal Varices Ligation Sucralfate - Ulcer Healing | Not applicable | Not yet recruiting | National Cheng-Kung University Hospital | 60 | 2026-07-01 | 2026-07-06 |
| A Prospective, Multicenter, Randomized Controlled Trial Investigating the Impact of Fasting Duration on Postoperative Rebleeding Following Esophageal Variceal Ligation. fasting periods of 24 hours, fasting periods of 48 hours, fasting periods of 6 hours - Esophageal Varices | Not applicable | Recruiting | The First Affiliated Hospital of Zhengzhou University | 339 | 2026-06-20 | 2026-08-19 |
| Ultrasound Prediction of Esophageal Variceal Bleeding Risk Variceal Bleeding, Ultrasonography | Not yet recruiting | Assiut University | 165 | 2026-04-01 | 2026-05-06 | |
| Apixaban-PK Trial: Preventing Portal Hypertension Complications in Cirrhosis Apixaban, Carvedilol, Placebo - Cirrhosis, Esophageal and Gastric Varices | Phase 4 | Recruiting | Asian Institute Of Medical Sciences | 220 | 2026-04-01 | 2026-04-09 |
| Pantoprazole After Prophylactic Endoscopic Variceal Treatment Pantoprazole - Esophageal and Gastric Varices, Liver Cirrhosis | Not applicable | Enrolling by invitation | General Hospital of Shenyang Military Region | 208 | 2026-03-27 | 2026-04-01 |
| Non-invasive Predictors of Esophageal Varices and Their Correlation to Upper Endoscopic Findings Esophageal Varices, Portal Hypertension | Not yet recruiting | Assiut University | 51 | 2026-03-20 | 2026-03-23 | |
| Optimizing Endoscopic and Interventional Treatment for Portal Hypertensive Bleeding Portal Hypertension, Gastroesophageal Varices Hemorrhage | Not yet recruiting | Shanghai Zhongshan Hospital | 1066 | 2026-03-17 | 2026-03-31 | |
| Evaluating the Efficacy of Vonoprazan in Preventing Post-Endoscopic Variceal Band Ligation Ulcers: A Randomized Controlled Trial Vonoprazan 20 mg, Placebo - Cirrhoses, Liver | Phase 2 | Recruiting | King Edward Medical University | 154 | 2025-12-16 | 2025-12-26 |
| The Diagnostic Value of Subharmonic Imaging Technology Combined With Liver Stiffness and Platelet Count for High-risk Esophageal and Gastric Varices in Patients With Liver Cirrhosis SHAPE - Liver Cirrhosis, Esophageal and Gastric Varices | Not applicable | Recruiting | The First Hospital of Jilin University | 380 | 2025-08-31 | 2026-05-05 |
| 2D-shear Wave Spleen Elastography in Clinically Significant Portal Hypertension and High-risk Varices Portal Hypertension Related to Cirrhosis, Esophageal Varices | Recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 450 | 2025-08-20 | 2025-11-25 | |
| Study on Portal Vein Pressure Gradient Measurement Under Endoscopic Ultrasound Guidance for Gastric Fundal Varices Esophageal and Gastric Varices | Completed | Second Affiliated Hospital, Zhejiang University, School of Medicine | 25 | 2025-07-01 | 2026-03-17 | |
| Prophylactic Endoscopic Variceal Ligation in Patients With High-risk Esophageal Varices Receiving Atezo/Bev for HCC Endoscopic variceal ligation (EVL) - Hepatocellular Carcinoma, Esophageal Varix | Phase 2 | Recruiting | Asan Medical Center | 44 | 2025-05-28 | 2025-07-24 |
| TIPS for Complicated Portal Hypertension Related to Porto-Sinusoidal Vascular Disease TIPS, Portal Hypertension | Recruiting | Centre Hospitalier Universitaire, Amiens | 360 | 2025-05-16 | 2025-11-19 | |
| Improve the Strategies of Endoscopic and Interventional Treatment of Gastroesophageal Hemorrhage in Portal Hypertension Esophageal Varices, Portal Hypertension | Recruiting | Shanghai Zhongshan Hospital | 1450 | 2025-03-01 | 2025-05-14 |
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Hypertension, Portal (49) · Liver Cirrhosis (36) · Fibrosis (30) · Gastrointestinal Hemorrhage (12) · Hemorrhage (10) · Carcinoma, Hepatocellular (5) · Hepatic Encephalopathy (5) · Liver Diseases (4) · Varicose Veins (4) · Ascites (3) · Hepatitis B (3) · Non-alcoholic Fatty Liver Disease (3) · Gastroesophageal Reflux (2) · Hematemesis (2)
Digestive System Diseases (135) · Gastrointestinal Diseases (135) · Esophageal Diseases (134) · Liver Diseases (131) · Hypertension, Portal (86) · Pathological Conditions, Signs and Symptoms (74) · Pathologic Processes (73) · Fibrosis (30) · Hemorrhage (11) · Cardiovascular Diseases (6) · Neoplasms (6) · Adenocarcinoma (5) · Brain Diseases, Metabolic (5) · Carcinoma (5) · Central Nervous System Diseases (5)
Carvedilol (15) · Endoscopy (10) · Propranolol (8) · Endoscopy, Digestive System (6) · Terlipressin (6) · Cyanoacrylates (4) · Enbucrilate (4) · Octreotide (4) · Polidocanol (4) · Cefotiam (2) · Ethiodized Oil (2) · Portasystemic Shunt, Transjugular Intrahepatic (2) · Rifaximin (2) · Somatostatin (2) · ambrisentan (2)
Shanghai Zhongshan Hospital (13) · Assiut University (8) · Tanta University (7) · West China Hospital (7) · Qilu Hospital of Shandong University (6) · Taipei Veterans General Hospital, Taiwan (6) · Beijing Friendship Hospital (3) · General Hospital of Shenyang Military Region (3) · Instituto Ecuatoriano de Enfermedades Digestivas (3) · Second Affiliated Hospital, Zhejiang University, School of Medicine (3) · Federal University of São Paulo (2) · Hvidovre University Hospital (2) · Kaohsiung Veterans General Hospital. (2) · King's College Hospital NHS Trust (2) · Mayo Clinic (2)
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Shiyao Chen, Professor (6) · Yanjing Gao, PhD.MD (3) · Rania M Elkafoury, MD (2) · Wen-Chi Chen, MD (2) · Xiaojuan Ou (2) · Adrian Reuben, M.D. (1) · Ahmed Maher, MD (1) · Ahmed Y Altonbary, MD (1) · Alban Denys, MD (1) · Alessandra Pivetti, MD (1) · Alvaro Koch, M.D. (1) · Amna Esmail Mohamed Tammam (1) · Amrik Shah, Sc.D. (1)
PMID 10922086, PMID 7721004, PMID 10744834, PMID 11176287, PMID 12003381, PMID 14687818, PMID 15044898, PMID 15100955, PMID 15544027, PMID 16437729, PMID 17141231, PMID 17643723, PMID 17997404, PMID 18167180, PMID 18760173, PMID 20073010, PMID 21135706, PMID 21199520, PMID 21889139, PMID 23891417, PMID 24947448, PMID 25339837, PMID 26047908, PMID 26139494, PMID 26452992, PMID 2679046, PMID 27786365, PMID 3262398, PMID 34115257, PMID 10343210, PMID 10643628, PMID 10643630, PMID 10922085, PMID 10934332, PMID 1109749, PMID 11328251, PMID 11343232, PMID 12648985, PMID 1421595, PMID 1446890, PMID 15094222, PMID 15562666, PMID 1568769, PMID 15691461, PMID 15743361, PMID 15743362, PMID 16306522, PMID 16374843, PMID 17227516, PMID 17352021
2018 (2), K24DK002650 (1), R01DK046580 (1)