37 completed, 26 unknown, 7 terminated, 5 active not recruiting. 87 Phase 1, 43 Phase 2.
Follow Foot Ulcer: new trials by email Literature Review of Foot Ulcer trials Research Report on Foot Ulcer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Placental Cells for Diabetic Foot Ulcers Placenta Stem Cells - Diabetic Foot Ulcer | Phase 1 | Not yet recruiting | Wake Forest University Health Sciences | 12 | 2027-03-01 | 2026-10-23 |
| Evaluating Autologous Platelet-Rich Fibrin Plasma for Chronic Diabetic Foot Ulcers PRFM, Standard of Care (SoC) - Diabetic Foot Ulcer (DFU), Ulcer | Phase 1 / Phase 2 | Not yet recruiting | Tiger Biosciences, LLC. | 55 | 2026-09-01 | 2026-09-25 |
| Standard Treatment Associated With Phage Therapy Versus Placebo for Diabetic Foot Ulcers Infected by S. Aureus Topical anti-Staphylococcus bacteriophage therapy, Topical placebo corresponding to anti-Staphylococcus bacteriophage therapy - Diabetic Foot, Staphylococcal Infections | Phase 1 / Phase 2 | Not yet recruiting | Centre Hospitalier Universitaire de Nīmes | 60 | 2026-09-01 | 2026-03-20 |
| Controlled Trial to Evaluate the Safety and Efficacy of CYWC628 (Human Dermal Fibroblast Spheroids) for the Treatment of Refractory Diabetic Foot Ulcers Compared With Standard of Care Standard of Care (SOC), SoC + Low dose CYWC628, SoC + High dose CYWC628 - Diabetic Foot Ulcer (DFU) | Phase 1 / Phase 2 | Recruiting | FibroBiologics | 120 | 2026-06-01 | 2026-08-26 |
| Phase 1 Study of VELGRAFT, a Living Cellular Construct, in the Management of Chronic Diabetic Foot Ulcers Which Have Attained Granulation Tissue an allogenic cell-based product, containing living human bone marrow-derived mesenchymal stem cells (MSCs) and MSCs differentiated into adipocytes on a porous chitosan-gelatin matrix, Standard of Care of Diabetic Foot Ulcers - Diabetic Foot Ulcer (DFU), Granulation of Chronic Diabetic Wounds | Phase 1 | Recruiting | Ayu, Inc. | 24 | 2026-03-11 | 2026-09-02 |
| Evaluation of ELU42 Topical Spray for the Treatment of Diabetic Foot Ulcers ELU42 Topical Spray - Diabetic Foot Ulcer, Wagner Grade 1 - 2 | Phase 1 / Phase 2 | Recruiting | Eluciderm Inc | 15 | 2025-11-10 | 2026-02-12 |
| Air-Dried Human Amniotic Membrane Terminally Sterilized by Gamma Irradiation for Multidisciplinary Clinical Application Air-Dried Human Amniotic Membrane (AD-hAM) - Diabetic Foot Ulcer (DFU), Ocular Disorder | Phase 1 | Active not recruiting | Libyan Center for Biotechnology Research | 2 | 2025-11-01 | 2026-06-29 |
| Safety and Preliminary Efficacy of TrophiPatch, an Adipose-Derived Stromal Cell Patch for Chronic Leg Ulcers TrophiPatch: allogeneic adipose-derived stromal cell patch - Diabetic Foot Ulcer (DFU), Venous Leg Ulcer (VLU) | Phase 1 / Phase 2 | Recruiting | Nicolò Brembilla | 18 | 2025-07-01 | 2025-07-02 |
| Use of Extracellular Vesicles (EV) for Diabetic Foot Ulcers Extracellular micro vesicles (EV) - Diabetic Foot Ulcer | Phase 1 | Active not recruiting | University of Jordan | 10 | 2024-12-01 | 2025-04-16 |
| Stem Cell Derived Exome for Treatment of Diabetic Foot Skin drug prepared with exome originated from stem cell - Diabetic Foot, Stem Cell | Phase 1 / Phase 2 | Not yet recruiting | Second Affiliated Hospital of Guangzhou Medical University | 50 | 2024-08-01 | 2024-06-28 |
| NOX1416 in Treatment of Chronic Non-Healing Diabetic Foot Ulcers NOX1416 and SOC, SOC (Standard of care) - Diabetic Foot Ulcer | Phase 1 | Active not recruiting | NOxy Health Products, LLC | 40 | 2024-06-06 | 2026-05-20 |
| Safety and Efficacy of Stem Cells for Diabetic Foot Ulcer Allogeneic mesenchymal stem cells (MSCs), Normal Saline - Diabetic Foot Ulcer | Phase 1 / Phase 2 | Unknown | Supergenics Life Science Sdn. Bhd. | 22 | 2024-05-01 | 2024-03-06 |
| Efficacy and Safety of Wharton's Jelly-Derived Mesenchymal Stem Cell Exosomes in the Treatment of Diabetic Foot Ulcers: A Double-blinded Randomized Controlled Clinical Trial WJ-MSC- Exosomes, SOC (Standard of care), Vehicle (placebo) - Diabetic Foot Ulcer (DFU), Exosomes | Phase 1 | Completed | Kafrelsheikh University | 110 | 2024-04-06 | 2025-04-29 |
| NOX1416 in Treatment of Chronic Non-Healing Diabetic Foot Ulcers (NTCDU) NOX-1416+SOC, Placebo+SOC - Diabetic Foot Ulcer | Phase 1 | Suspended | NOxy Health Products, LLC | 30 | 2023-08-16 | 2024-01-16 |
| Effect of Mesenchymal Stem Cells on Healing of Foot Ulcers in Diabetes Patients. Adipose tissue derived mesenchymal stromal/stem cells (Cell2Cure®) - Diabetic Foot Ulcer, Mesenchymal Stromal Cells | Phase 1 | Terminated | Cell to Cure ApS | 21 | 2022-12-15 | 2025-12-23 |
| Study to Assess the Safety of DERMASEAL for Diabetic Foot Ulcers DERMASEAL, Plasma Film, Standard of Care - Foot Ulcer, Diabetic | Phase 1 | Active not recruiting | Vitruvian Medical Devices, Inc. | 26 | 2022-10-03 | 2024-12-27 |
| Omeza Products in Combination With Standard of Care for the Treatment of Diabetic Foot Ulcers Omeza collagen matrix, Omeza lidocaine lavage, Omeza skin protectant - Diabetic Foot Ulcers | Phase 1 | Completed | Omeza, LLC | 25 | 2022-09-01 | 2024-06-21 |
| A Clinical Intervention Study of Tangningtongluo on Diabetic Foot Ulcer Standardized Western Medicine Treatment, Tangningtongluo tablet and cream, Tangningtongluo tablet - Diabetic Foot Ulcer | Phase 1 | Unknown | Affiliated Hospital of Nantong University | 80 | 2022-01-15 | 2022-03-18 |
| Study for Treatment of Chronic Diabetic Foot Ulcers With the Investigational Allogeneic Cell Therapy Product, hOMSC200 hOMSC200, Placebo - Diabetic Foot, Diabetic Foot Ulcer | Phase 1 | Unknown | Cytora Ltd. | 21 | 2022-01-06 | 2024-03-13 |
| Safety, Tolerability and Efficacy of CYP-006TK in Adults with Diabetic Foot Ulcers CYP-006TK - Diabetic Foot Ulcer, Cutaneous Ulcer | Phase 1 | Completed | Cynata Therapeutics Limited | 30 | 2022-01-04 | 2025-01-24 |
Showing 20 of 87. Sign in to see all of them.
Diabetic Foot (85) · Diabetes Mellitus (18) · Peripheral Vascular Diseases (7) · Ischemia (5) · Chronic Limb-Threatening Ischemia (4) · Diabetes Complications (4) · Ulcer (4) · Wounds and Injuries (4) · Bronchiolitis Obliterans Syndrome (3) · Leg Ulcer (3) · Burns (2) · Gangrene (2) · Inflammation (2) · Peripheral Arterial Disease (2)
Endocrine System Diseases (87) · Skin Diseases (87) · Skin and Connective Tissue Diseases (87) · Cardiovascular Diseases (85) · Diabetic Angiopathies (85) · Diabetic Neuropathies (85) · Skin Ulcer (85) · Vascular Diseases (85) · Leg Ulcer (84) · Diabetes Complications (81) · Diabetes Mellitus (69) · Glucose Metabolism Disorders (18) · Metabolic Diseases (18) · Nutritional and Metabolic Diseases (18)
Standard of Care (11) · Sodium Chloride (4) · Saline Solution (2) · Becaplermin (1) · Borates (1) · Cell- and Tissue-Based Therapy (1) · Ciprofloxacin (1) · Collagenases (1) · Debridement (1) · Doxycycline (1) · Drug Evaluation (1) · Drug Therapy (1) · Equipment and Supplies (1) · Excipients (1) · Extracorporeal Shockwave Therapy (1)
Jie Shen (3) · Hadassah Medical Organization (2) · Hanan Jafar (2) · NOxy Health Products, LLC (2) · South China Research Center for Stem Cell and Regenerative Medicine (2) · Stratatech, a Mallinckrodt Company (2) · Affiliated Hospital of Nantong University (1) · Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud (1) · Andalusian Network for Design and Translation of Advanced Therapies (1) · Anterogen Co., Ltd. (1) · Aposcience AG (1) · Aurealis Oy (1) · Ayu, Inc. (1) · Beijing Tongren Hospital (1) · Beike Biotech India Pvt.ltd (1)
United States (22) · China (9) · Israel (8) · Germany (4) · Taiwan (4) · India (3) · Poland (3) · United Kingdom (3) · Australia (2) · Denmark (2) · France (2) · Jordan (2) · New Zealand (2) · Spain (2) · Austria (1)
Jie Shen (3) · Abdallah Awidi, MD (1) · Albert Sotto, MD, PhD (1) · Alireza Goodarzi, MSc (1) · Andreas Kerstan, Dr. (1) · Antonio Chacon, MD, PhD (1) · Antonio de la Cuesta, MD (1) · Arthur Tucker, PhD (1) · Azra Mehmood, PhD (1) · Barbara Sosnowski, PhD (1) · Beata Mrozikiewicz-Rakowska, . Assoc.Prof. (1) · Behnam Molavi, MD (1) · Cecilia Low Wang, MD (1)
PMID 20798179, PMID 22289660, PMID 26054585, PMID 28133924, PMID 29631615, PMID 29854007, PMID 30917698, PMID 33011075, PMID 33407796, PMID 33504262, PMID 34052927, PMID 34398099, PMID 36064604, PMID 39740667, PMID 39838970
2018 (2), 2008 (1), 2015 (1), 2016 (1), R01HD036802 (1), R44AR046154 (1), R44DK069924 (1)